SuperfamilyEnzymeGlycoside hydrolaseHydrolysisCatalyticKinaseCONTAINS InterPro DOMAINStructural ClassifiEnzymesAbundantResiduesGenesExohydrolaseMolecularEncodesBacterialInteractionActivityExtracellularFoldSequenceAminoRibosomalBiologicalCorrespondsGeneBetaFunctionMotifNucleotideMicrobialPredictionStructureFamilies
Superfamily1
- BEST Arabidopsis thaliana protein match is: RNI-like superfamily prote. (riken.jp)
Enzyme2
- The heterodimeric glucosidase II enzyme has an important function in protein folding and catalyzes the hydrolysis of glucose residues. (wikipedia.org)
- A multidisciplinary approach is required to achieve this goal, involving precursor synthesis, enzyme screening, heterologous protein expression, enzyme mutagenesis, biocatalyst (co)-immobilization, bioreactor design and chiral product analysis. (cost.eu)
Glycoside hydrolase2
- The presence of all epitopes can be differentially modulated in vitro using glycoside hydrolase family 43 and family 51 arabinofuranosidases. (megazyme.com)
- Other β-agarases belong to glycosyl hydrolase families 16 and 50, with all three groups containing a conserved glycoside hydrolase region responsible for catalysis (Fu and Kim 2010). (worthington-biochem.com)
Hydrolysis2
- Chitinases are glycosyl hydrolases that catalyze the hydrolysis of the β-1,4 linkages in complex carbohydrates and those that contain GlcNAc. (researchgate.net)
- Agarases are glycoside hydrolases that catalyze the hydrolysis of agar. (worthington-biochem.com)
Catalytic2
- Based on catalytic domain similarities, β-Agarase II of Pseudoalteromonas atlantica has been designated part of the glycosyl hydrolase 86 (GH86) family. (worthington-biochem.com)
- We also analyzed the evolutionary modularity of a data set of α -amylase catalytic domain homologs, and the dynamic modularity of the Niemann-Pick C1 (NPC1) protein N-terminal domain. (biomedcentral.com)
Kinase1
- Recent research shows that the treatment with protein kinase C (PKC) inhibitor may help to mimic the increase of PKD3, by RacV12 and aluminum fluoride. (wikipedia.org)
CONTAINS InterPro DOMAIN1
- CONTAINS InterPro DOMAIN/s: Protein-tyrosine phosphatase-like, PTPLA (InterP. (riken.jp)
Structural Classifi2
- SCOPe: Structural Classification of Proteins - extended. (berkeley.edu)
- SCOP: Structural Classification of Proteins and ASTRAL. (berkeley.edu)
Enzymes3
- We show that these microarrays are suitable for the high throughput characterization of the recognition capabilities of monoclonal antibodies, carbohydrate-binding modules, and other oligosaccharide-binding proteins of biological significance and also that they have potential for the characterization of carbohydrate-active enzymes. (megazyme.com)
- The sequence similarities of the enzymes with their respective closest homologues are 59 % for HEX1 and 51 % for HEX2 on the protein level. (dtu.dk)
- Furthermore, the transcriptional responses of B5 at different temperature by using rice straw as sole carbon sources were also analyzed, based on which the mechanism of lignocellulose degradation at high temperature was revealed that B5 could resist the heat by up-regulating the heat shock proteins (HSP) and then secrete various Carbohydrate-Active enzymes (CAZymes) to realize energy balance. (researchsquare.com)
Abundant1
- Various differentially abundant transcripts encoded glycosyl hydrolases (GHs). (mpg.de)
Residues2
- This involves a large conformational change in residues 81 to 83 and smaller shifts that extend 20 angstroms across the protein surface. (rcsb.org)
- The 37-Mb genome was predicted to contain a total of 12,074 genes encoding proteins with a length greater than 100 amino acid residues (see Methods). (nature.com)
Genes1
- In winter, greatest transcript levels were observed for stress-responsive genes known to encode proteins that efficiently protect microbial cells against freezing damage, such as GroEL and Hsp20. (mpg.de)
Exohydrolase1
- Three-dimensional structure of a barley beta-D-glucan exohydrolase, a family 3 glycosyl hydrolase. (expasy.org)
Molecular1
- The tertiary structure of proteins provides crucial information for understanding molecular mechanisms of biological functions. (biomedcentral.com)
Encodes1
- Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. (thermofisher.com)
Bacterial3
- Here we report the temporal measurements of absolute RNA and protein levels per gene within a mixed bacterial-archaeal consortium. (nature.com)
- Our analysis of this data reveals an absolute protein-to-RNA ratio of 10 2 -10 4 for bacterial populations and 10 3 -10 5 for an archaeon, which is more comparable to Eukaryotic representatives' humans and yeast. (nature.com)
- Indeed, the protein-to-RNA ratio per sample of the bacterial populations matched previous calculations for the existing example from axenically cultured E. coli 2 . (nature.com)
Interaction2
- Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules. (pdbj.org)
- DctA and DcuB exert regulatory functions and link transport to metabolic control through interaction with regulatory proteins. (bvsalud.org)
Activity2
- Glycosyl hydrolase family GH32 cleaves sucrose into fructose and glucose via beta-fructofuranosidase activity, producing invert sugar that is a mixture of dextrorotatory D-glucose and levorotatory D-fructose, thus named invertase (EC 3.2.1.26). (unl.edu)
- FUNCTIONS IN: hydrolase activity, inositol or phosphatidylinosi. (riken.jp)
Extracellular1
- The NH 2 terminus of the protein may function as a signal peptide in the export of extracellular β-agarase. (worthington-biochem.com)
Fold6
- To seek the most effective definition of residue contacts for template-based protein structure prediction, we evaluated 45 different contact definitions, varying bases of contacts and distance cutoffs, in terms of their ability to identify proteins of the same fold. (biomedcentral.com)
- Lower fold recognition accuracy was observed when inaccurate threading alignments were used to identify common residue contacts between protein pairs. (biomedcentral.com)
- In the case of threading, alignment accuracy strongly influences the fraction of common contacts identified among proteins of the same fold, which eventually affects the fold recognition accuracy. (biomedcentral.com)
- The largest deterioration of the fold recognition was observed for β-class proteins when the threading methods were used because the average alignment accuracy was worst for this fold class. (biomedcentral.com)
- When results of fold recognition were examined for individual proteins, we found that the effective contact definition depends on the fold of the proteins. (biomedcentral.com)
- Residue contacts defined by Cβ−Cβ distance of 7.0 Å work best overall among tested to identify proteins of the same fold. (biomedcentral.com)
Sequence1
- Most attempts made focus on sequence motifs of protein-protein interactions, binding sites, or sequence conservancy. (biomedcentral.com)
Amino2
- To investigate the relation between protein stability and the predicted stabilities of individual secondary structural elements, residue Pro86 in an alpha-helix in phage T4 lysozyme was replaced by ten different amino acids. (rcsb.org)
- Unexpectedly, all ten amino acid substitutions marginally reduce protein thermostability. (rcsb.org)
Ribosomal1
- Vater CA, Bartle LM, Leszyk JD, Lambert JM, Goldmacher VS. Ricin A chain can be chemically cross-linked to the mammalian ribosomal proteins L9 and L10e. (umassmed.edu)
Biological1
- The presence of this motif in proteins found only in organisms that are not typically exposed to light raises the possibility of direct biological relevance for this new type of protein reaction. (ox.ac.uk)
Corresponds2
- This domain corresponds to the N-terminal domain of glycosyl hydrolase family 32 which forms a five bladed beta propeller structure. (nih.gov)
- For example, when Escherichia coli is grown axenically in steady state, we can expect that each RNA molecule corresponds to 10 2 -10 4 of the matching protein (absolute protein-to-RNA ratio, hereafter referred protein-to-RNA ratio) and the variation in the level of cellular RNA explains ~29% of the variation in the amount of detectable protein 2 . (nature.com)
Gene2
- Polycystic kidney disease 3 (autosomal dominant) is a protein that in humans is encoded by the PKD3 gene. (wikipedia.org)
- 5 of the mutations from the GANAB gene were predicted to result in a short protein (frameshift, nonsense, or splicing), and 3 missense mutations. (wikipedia.org)
Beta1
- Glycosyl hydrolase family 32, beta-fructosidases. (unl.edu)
Function2
- While the field of microbiology has adapted to the study of complex microbiomes via modern meta-omics techniques, we have not updated our basic knowledge regarding the quantitative levels of DNA, RNA and protein molecules within a microbial cell, which ultimately control cellular function. (nature.com)
- In the cytoplasm, a chain or cluster of ribosomes form polyribosomes which function as a continuous protein factory that translates mRNA into polypeptide chains. (kenyon.edu)
Motif2
- Unprecedented photochemical, site-selective cleavage of a His-Trp (HW) motif in the GH1 family TIM-barrel proteins is observed upon exposure to 240-308 nm light to cleanly release N-terminal primary amide and C-terminal indolylenamide fragments. (ox.ac.uk)
- We also show that this photocleaveable motif can be transferred to fusion proteins for use in photoresponsive affinty purification. (ox.ac.uk)
Nucleotide1
- FUNCTIONS IN: protein binding, nucleotide bindi. (riken.jp)
Microbial2
- In this context, the exploration of temporal interplay between populations with different lifestyles (comprising metabolism, motility, sporulation, etc.) becomes of primary importance to interpret the changes in fundamental quantities in a microbial community, such as the protein-to-RNA ratio that ultimately impacts the overarching community phenotype(s). (nature.com)
- In order to perform studies of such design and test if previously defined quantitative data about the functioning of microorganisms (i.e., protein-to-RNA ratio) is applicable to real world consortia, we must first sample microbial communities across transition events and employ quantification techniques that are absolute. (nature.com)
Prediction2
- Effective encoding of residue contact information is crucial for protein structure prediction since it has a unique role to capture long-range residue interactions compared to other commonly used scoring terms. (biomedcentral.com)
- A proper encoding of residue contact information is crucial for structure prediction because in principle, a full distance map or a residue contact map has sufficient information for reconstructing the tertiary structure of a protein[ 25 ]. (biomedcentral.com)
Structure3
- Among various structure-based terms, residue-residue contact potentials[ 21 - 23 ] are unique in that they capture long-range interactions in a protein structure[ 24 ]. (biomedcentral.com)
- In the protein world, the phenotype is the structure and the phenotypic variance is given by slight variations in protein structure shape. (biomedcentral.com)
- Nonenzymatic, chemical methods for the controlled cleavage of proteins at predictable sites in a site-specific manner are rare and of strong potential utility in clean, post-translational manipulation of protein structure for use in, for example, proteomics, sequencing, and tagged-protein production. (ox.ac.uk)
Families1
- the glycosyl hydrolase 31 families of proteins. (wikipedia.org)