• In enzymology, a protein-histidine N-methyltransferase (EC 2.1.1.85) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + protein L-histidine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + protein Ntau-methyl-L-histidine Thus, the two substrates of this enzyme are S-adenosyl methionine and protein L-histidine, whereas its two products are S-adenosylhomocysteine and protein Ntau-methyl-L-histidine. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction: [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrosarcinapterin ⇌ {\displaystyle \rightleftharpoons } [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrosarcinapterin This enzyme catalyses the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction [Methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate ⇌ {\displaystyle \rightleftharpoons } a [Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate This enzyme catalyses the transfer of a methyl group from the N5 position of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein. (wikipedia.org)
  • In both types of histone methyltransferases, cofactor S-Adenosyl methionine (SAM) serves as a cofactor and methyl donor group. (wikipedia.org)
  • Recent findings indicate that protein carboxyl methyltransfer-ases (PCMTs) from mammalian brain and erythrocytes selectively and stoichiometrically methylate peptides and proteins which contain L-isoaspartyl (isoAsp) sites, i. e., aspartate which is linked via its side-chain β -carboxyl group, rather than via the typical α -carboxyl linkage (reviewed in reference 1). (springer.com)
  • This enzyme catalyses the following chemical reaction dimethylamine + [Co(I) dimethylamine-specific corrinoid protein] ⇌ {\displaystyle \rightleftharpoons } [methyl-Co(III) dimethylamine-specific corrinoid protein] + methylamine This enzyme is involved in methanogenesis from dimethylamine. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction S-adenosyl-L-methionine + [phosphatase 2A protein]-leucine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + [phosphatase 2A protein]-leucine methyl ester Methylates the C-terminal leucine of phosphatase 2A. (wikipedia.org)
  • The enzyme catalyzes the chemical reaction S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester Thus, the two substrates of this enzyme are S-adenosyl methionine and protein C-terminal S-farnesyl-L-cysteine, whereas its two products are S-adenosylhomocysteine and protein C-terminal S-farnesyl-L-cysteine methyl ester. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M ⇌ {\displaystyle \rightleftharpoons } methyl-CoM + [Co(I) methanol-specific corrinoid protein] Free methylcob(I)alamin can substitute for the corrinoid protein in vitro. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction [methyl-Co(III) tetramethylammonium-specific corrinoid protein] + coenzyme M ⇌ {\displaystyle \rightleftharpoons } methyl-CoM + [Co(I) tetramethylammonium-specific corrinoid protein] This enzyme catalyses the transfer of a methyl group from a corrinoid protein. (wikipedia.org)
  • This enzyme catalyses the following chemical reaction [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M ⇌ {\displaystyle \rightleftharpoons } methyl-CoM + [Co(I) methylamine-specific corrinoid protein] This enzyme contains zinc. (wikipedia.org)
  • The yeast two-hybrid protein-protein interaction assay led to the identification of an array of receptor-interacting factors in David Moore's laboratory and RIP140 repressive protein was discovered in Malcolm Parker's laboratory. (wikipedia.org)
  • The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor. (semanticscholar.org)
  • Transcriptional activation by NRs is mediated by the NR (or p160) coactivators, a family of three related 160-kD proteins that includes SRC-1, GRIP1/TIF2, and pCIP/RAC3/ACTR/AIB1/TRAM1 ( 2 ). (sciencemag.org)
  • Interestingly, these altered protein levels are due to post-transcriptional mechanisms as the corresponding mRNA levels are unaffected. (jneurosci.org)
  • NCoA-2 is also frequently called glucocorticoid receptor-interacting protein 1 (GRIP1), steroid receptor coactivator-2 (SRC-2), or transcriptional mediators/intermediary factor 2 (TIF2). (wikipedia.org)
  • NCoA-2 is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. (wikipedia.org)
  • PRDM2 has been shown to interact with Estrogen receptor alpha and Retinoblastoma protein. (wikipedia.org)