Tumor Suppressor Protein p53Tumor Suppressor ProteinsGenes, Tumor SuppressorProto-Oncogene Proteins c-mdm2Protein Kinase CProtein KinasesVon Hippel-Lindau Tumor Suppressor ProteinProtein BindingPhosphorylationApoptosisCell Line, TumorCyclin-Dependent Kinase Inhibitor p21Molecular Sequence DataCell LineNuclear ProteinsTumor Suppressor Protein p14ARFTransfectionMutationGenes, p53Protein-Serine-Threonine KinasesProto-Oncogene ProteinsTumor Cells, CulturedCyclinsDNA-Binding ProteinsAmino Acid SequenceSignal TransductionRetinoblastoma ProteinBase SequenceCell CycleTranscriptional ActivationDNA DamageCell Cycle ProteinsTranscription FactorsBinding SitesTranscription, GeneticPromoter Regions, GeneticCyclic AMP-Dependent Protein KinasesBlotting, WesternProtein Structure, TertiaryGene Expression Regulation, NeoplasticCalcium-Calmodulin-Dependent Protein KinasesCells, CulturedRNA, MessengerUbiquitin-Protein LigasesCell DivisionDown-RegulationCell ProliferationHeLa CellsGene Expression RegulationPhosphatidylinositol 3-KinasesMitogen-Activated Protein KinasesFibroblastsMAP Kinase Signaling SystemRecombinant Fusion ProteinsProtein Kinase InhibitorsOncogene Proteins, ViralEnzyme ActivationDNAPrecipitin Testsp38 Mitogen-Activated Protein KinasesAdenovirus E1B ProteinsRecombinant ProteinsUltraviolet RaysCell NucleusSerineNeoplasmsUbiquitinsDNA PrimersNeurofibromin 2Consensus SequenceProteasome Endopeptidase Complexbcl-2-Associated X ProteinTrans-ActivatorsAntigens, Polyomavirus TransformingAdenomatous Polyposis Coli ProteinCyclin-Dependent Kinase Inhibitor p16Models, BiologicalSpodopteraMice, KnockoutMitogen-Activated Protein Kinase 1Cell Transformation, NeoplasticCell SurvivalProteinsPTEN PhosphohydrolaseRNA, Small InterferingGenes, SuppressorPhosphoproteinsCarrier ProteinsCyclin-Dependent KinasesJNK Mitogen-Activated Protein KinasesNeoplasm ProteinsMitogen-Activated Protein Kinase KinasesProto-Oncogene Proteins c-bcl-2Protein Kinase C-alphaMitogen-Activated Protein Kinase 3Enzyme InhibitorsRepressor ProteinsIntracellular Signaling Peptides and ProteinsProtein Kinase C-deltaAcetylation