• Inhaled fluticasone propionate (FP) is widely used to reduce pulmonary inflammation in chronic obstructive pulmonary disease, but the potential effects of FP on airway epithelial cells from patients with cystic fibrosis (CF) are unknown. (ersjournals.com)
  • In CF disease, a nonregulated inflammatory lung response occurs through exaggerated nuclear factor (NF)-κB activation and elevated pro-inflammatory cytokines production by airway epithelial cells. (ersjournals.com)
  • Cystic fibrosis (CF) is a lethal inherited disorder caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) in airway epithelial cells 1 . (ersjournals.com)
  • One of the major clinical manifestations of CFTR mutations is neutrophil dominated inflammation 2 , 3 , implying that defective CFTR affects the immune function of airway epithelial cells, in particular the production of nuclear factor (NF)-κB-dependent chemokines. (ersjournals.com)
  • 16-membered) on MUC5AC and MUC2 gene expression and secretion from human airway epithelial cells. (karger.com)
  • The present study demonstrates that AZM and MDM suppress the synthesis of mucin and TNF-α from human airway epithelial cells. (karger.com)
  • Kim YD, Cho JS, Kim HS, Song SH: Effect of macrolide on the interleukin-1 β-mediated MUC2/5AC genes expression and mucin secretion in human airway epithelial cells. (karger.com)
  • Shimizu T, Shimizu S: Azithromycin inhibits mucus hypersecretion from airway epithelial cells. (karger.com)
  • Cigana C, Assael BM, Melotti P: Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells. (karger.com)
  • Finally, ODE-induced Muc5ac levels were enhanced in MyD88-deficient airway epithelial cells in vitro. (cdc.gov)
  • The isolated CTCs are then cultured in tissue culture plates pre-coated with antibodies which capture the secreted protein of interest. (medscape.com)
  • The EasySep™ procedure involves labeling unwanted non-epithelial cells with biotinylated antibodies and magnetic particles. (stemcell.com)
  • They are also called epithelial reticular cells, or epithelioreticular cells (ERC). (wikipedia.org)
  • To determine whether FP reduces cytokine production in bronchial epithelial cells via NF-κB, the authors investigated the nonstimulated and the Pseudomonas aeruginosa lipopolysaccharide (LPS) stimulated production of NF-κB-dependent interleukin (IL)-6, IL-8 and RANTES (regulated on activation, T-cell expressed and secreted) along with the activation of NF-κB in non-CF and CF human bronchial gland epithelial cells. (ersjournals.com)
  • It was demonstrated that a relevant concentration of FP (10 −8 M) inhibited constitutive and P. aeruginosa LPS-induced IL-6 and IL-8 production of non-CF and CF bronchial epithelial cells. (ersjournals.com)
  • Interestingly, the expression of two IκB kinases (IKK)-α/β, the degradation of cytosolic IκB-β inhibitor and the NF-κB deoxyribonucleic acid binding activity were markedly reduced after FP treatment in both CF and non-CF bronchial epithelial cells. (ersjournals.com)
  • It was shown by the authors that fluticasone propionate exerts an anti-inflammatory effect by blocking a signal transduction leading to a reduced level of IκB-α/β kinases in bronchial epithelial cells. (ersjournals.com)
  • In particular the strong effect on the IκB-β kinase, which is known to be elevated in bronchial epithelial cells in cystic fibrosis patients, was observed. (ersjournals.com)
  • The present authors and previous studies, have previously demonstrated that epithelial expression of interleukin (IL)-8 is excessively elevated in the bronchial epithelial cells of human CF adults 6 . (ersjournals.com)
  • Case-control studies have shown that the E1A DNA from group C adenoviruses is present in greater amounts in the lungs of patients with COPD than in controls with normal lung function matched for age, sex and smoking history 5 , and that the excess inflammation in the lungs of smokers with severe emphysema is associated with increased numbers of alveolar epithelial cells expressing E1A 6 . (ersjournals.com)
  • Discussion: In conclusion, our data indicate that bronchial and alveolar epithelial cells respond differently to hypoxia and profibrotic stimuli. (lu.se)
  • The in vitro treatment of intestinal epithelial cell lines with cytokines resulted in increased CK2 expression and nuclear translocation of its catalytic alpha subunit. (diva-portal.org)
  • Ribosomal protein L10 (RPL10) is one of large ribosomal proteins and plays a role in Wilms' tumor and premature ovarian failure. (jcancer.org)
  • However, the function of RPL10 in human epithelial ovarian cancer (EOC) remains unknown. (jcancer.org)
  • Prior small studies have shown increased expression of sperm protein 17 (Sp17) in epithelial ovarian cancer (EOC) tissue and suggest Sp17 as a potential biomarker for EOC. (biomedcentral.com)
  • Epithelial ovarian cancer (EOC) is the fifth most common cause of female cancer-related deaths. (biomedcentral.com)
  • One CTA that has been proposed as a potential biomarker for ovarian cancer is sperm protein 17 (Sp17). (biomedcentral.com)
  • Recent studies have shown that cancer-associated fibroblasts (CAFs) and the epithelial-mesenchymal transition (EMT) contribute to invasive and metastatic abilities of ovarian cancer (OC) cells. (oncotarget.com)
  • To investigate the effects of zerumbone on cell invasion, epithelial-mesenchymal transition (EMT) and the potential signaling pathway involved in ovarian cancer cells. (ajol.info)
  • Background: The neural transcription factor SOX11 has been described as a prognostic marker in epithelial ovarian cancers (EOC), however its role in individual histological subtypes and tumour grade requires further clarification. (lu.se)
  • Role of serotype and virulence determinants of Streptococcus pyogenes biofilm bacteria in internalization and persistence in epithelial cells in vitro. (lu.se)
  • Dive into the research topics of 'Role of serotype and virulence determinants of Streptococcus pyogenes biofilm bacteria in internalization and persistence in epithelial cells in vitro. (lu.se)
  • Thymic epithelial cells (TECs) are specialized cells with high degree of anatomic, phenotypic and functional heterogeneity that are located in the outer layer (epithelium) of the thymic stroma. (wikipedia.org)
  • Cortical thymic epithelial cells (cTECs) are presented in the outer thymic cortex region, in comparison with medullary thymic epithelial cells (mTECs) located in the inner thymic medulla. (wikipedia.org)
  • These cells are also called thymic epithelial progenitors cells (TEPCs) and they provide that cortical and medullary epithelial thymocytes share an origin in the postnatal thymus. (wikipedia.org)
  • Thymic epithelial neoplasms or tumors, also known as thymoma and thymic carcinoma, are the most common primary neoplasms of the anterior mediastinum. (medscape.com)
  • The Masaoka-Koga classification describes the extent and spread of thymic epithelial malignancies. (medscape.com)
  • The eighth edition of the TNM classification of malignant tumors includes an official staging system for thymic epithelial tumors recognized by the American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC). (medscape.com)
  • Thymic epithelial tumors with clearly invasive or metastatic features seen on CT are associated with having higher AJCC/UICC pathologic TNM stage. (medscape.com)
  • Sp17 expression was limited in other benign and non-epithelial malignant neoplasms. (biomedcentral.com)
  • Dysregulation of Notch has been implicated in the tumorigenesis of some odontogenic neoplasms but its role in the calcifying epithelial odontogenic tumor (CEOT) remains unclarified. (um.edu.my)
  • Epithelial-mesenchymal transformation is now recognised as an important feature of tissue remodelling. (ersjournals.com)
  • Reports from several laboratories suggest that a phenomenon termed epithelial-mesenchymal transformation, in which epithelial cells transform into fibroblasts capable of producing connective tissue matrix, is an important feature of tissue remodelling 10 , 11 . (ersjournals.com)
  • In the present study, the hypothesis that adenoviral infection followed by persistent expression of its E1A gene is capable of producing epithelial-mesenchymal transformation was examined by investigating guinea pig PLECs that express adenoviral E1A. (ersjournals.com)
  • More importantly, through direct chromatin binding and induction of epigenetic alterations, GRHL factors function as potent suppressors of oncogenic cellular dedifferentiation program - epithelial-mesenchymal transition and its associated tumor -promoting phenotypes such as tumor cell migration and invasion. (bvsalud.org)
  • Epithelial-mesenchymal transition (EMT) is defined as switching of polarized epithelial cells to a migratory fibroblastoid phenotype. (biomedcentral.com)
  • Loss of epithelial proteins and/or acquisition of the expression of mesenchymal proteins were observed in lung adenocarcinoma. (biomedcentral.com)
  • Epithelial-mesenchymal transition (EMT) consists of a rapid and often reversible change of cell phenotype. (biomedcentral.com)
  • During EMT, cells lose or redistribute epithelial proteins and acquire mesenchymal proteins. (biomedcentral.com)
  • Mal interacted with several protein kinase C (PKC) isoforms in a Caco-2 model of intestinal epithelia and inhibition of Mal or PKC increased permeability and bacterial invasion via a paracellular route, while a pan-PKC inhibitor increased susceptibility to oral infection in mice. (elsevierpure.com)
  • Dive into the research topics of 'MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C'. Together they form a unique fingerprint. (elsevierpure.com)
  • The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. (cancerindex.org)
  • E1A transfection results in the transformation of peripheral lung epithelial cells and normal lung fibroblasts to a phenotype intermediate between that of the two primary cells. (ersjournals.com)
  • The changes that occur during adenoviral E1A transformation of primary guinea pig PLECs were also compared with those occurring during the transformation of the fibroblasts that frequently contaminate primary epithelial cultures, and evidence is presented that both cell types are transformed to an intermediate phenotype. (ersjournals.com)
  • GRHL proteins are essentially associated with the development and maintenance of the epithelial phenotype across diverse physiological conditions such as epidermal differentiation and craniofacial development as well as pathological functions including hearing impairment and neural tube defects . (bvsalud.org)
  • As a result, cells loss epithelial polarity and acquire a spindle-shaped, highly motile fibroblastoid phenotype. (biomedcentral.com)
  • TEC development require activity of other molecules and transcriptional regulators, such as protein 63 (p63) that is involved in homeostasis of various epithelial lineages, chromobox homolog 4 (Cbx4) which regulates cell proliferation and differentiation, fibroblast growth factors Fgf7 and Fgf10 that initiate TEC expansion, TNFT, CD40, lymfotoxin β receptor (LTβR) and Hedgehog signaling pathway, which could reduce TEC cells in fetal and postnatal thymus. (wikipedia.org)
  • These results demonstrate that ChoK plays an essential role in both normal human mammary epithelial cell proliferation and breast tumor progression. (aacrjournals.org)
  • Here, we have investigated the role of ChoK in the development of breast cancer and found that ChoK is both necessary and sufficient for growth factor-induced proliferation in primary human mammary epithelial cells and an absolute requirement for the specific mitogenic response to heregulin in breast tumor-derived cells. (aacrjournals.org)
  • Note that trans‐Golgi cisternae in lactating mammary cells contain large amounts of casein and other milk proteins and are grossly expanded due to the osmolarity of the secreted fluid. (cellimagelibrary.org)
  • The EasySep™ Mouse Epithelial Cell Enrichment Kit II is designed to isolate epithelial cells from freshly dissociated mouse mammary tissues by immunomagnetic negative selection. (stemcell.com)
  • Enhanced mucosal CK2 protein expression and activity were observed in animal models of chronic colitis, particularly within intestinal epithelial cells (IECs). (diva-portal.org)
  • RPL10 protein expression was detected by immunohistochemistry and Western blot. (jcancer.org)
  • The ITCM was harvested from all donor explant cultures and placed on recipient HaCaT cells to observe any change in protein expression caused by the bystander signals. (tudublin.ie)
  • A down-regulation of mRNA expression was observed for the main regulators of p53 protein stability during infection by the complete set of viruses tested, and a significant decrease in p53 mRNA expression was also observed in H5N1 infected cells. (nih.gov)
  • Increased expression of specific heat shock proteins (HSPs) in CD patients protects intestinal epithelial cells (IECs) from death. (dal.ca)
  • Increasing evidence suggests that respiratory epithelial cells with dysfunctional CFTR have exaggerated activation of NF-κB/inhibitor of NF-κB complex associated with upregulated expression of chemokines 4 , 5 . (ersjournals.com)
  • AZM and MDM attenuated PMA-induced MUC5AC and MUC2 gene and protein expression in NCI-H292 cells. (karger.com)
  • The expression of EMT-related proteins including cytokeratin, E-cadherin, TTF-1, β-catenin, vimentin, Snail, Twist, CD44 was evaluated by immunohistochemistry using a tissue array method in the lung adenocarcinoma tissues of 95 patients. (biomedcentral.com)
  • In addition, clinicopathological characteristics and survival were compared with the expression of EMT-related proteins. (biomedcentral.com)
  • Specifically, enteral exposure of 2 wk-old mice to commensal E. coli for 24 h selectively increased both IFN-αA and GBP-1 mRNA expression and prevented staurosporine-induced epithelial apoptosis. (elsevierpure.com)
  • These findings identify a role for IFN-αA-mediated GBP-1 expression in the prevention of intestinal epithelial apoptosis by commensal bacteria. (elsevierpure.com)
  • mRNA expression of genes and proteins related to disease pathology were. (lu.se)
  • Protein expression was determined by western blot. (ajol.info)
  • MyD88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultur al organic dust exposure. (cdc.gov)
  • Compared with ODE-challenged WT mice, ODE-challenged, MyD88-deficient mice demonstrated significantly increased Muc5ac immunostaining, protein levels by immunoblot, and expression by quantitative PCR. (cdc.gov)
  • Scope includes mutations and abnormal protein expression. (cancerindex.org)
  • Expression of the L1 protein using recombinant DNA technology produces noninfectious virus-like particles (VLPs). (cdc.gov)
  • Introduction: Changes in the expression of Wnt proteins in oral squamous cell carcinoma allowed the construction of hypothesis about the role of Wnt-5a in potential malignant disorders. (bvsalud.org)
  • Objective: To evaluate the immunohistochemistry expression of the protein wnt-5a in oral epithelial dysplasia. (bvsalud.org)
  • The expression of Wnt-5a protein was evaluated as membranous, cytoplasmatic and/or nuclear. (bvsalud.org)
  • Conclusion: The increased immuno-expression of the protein Wnt-5a observed in oral epithelial dysplasias, differ significantly from the normal pattern of healthy oral mucosa and shows a phenotypic change of epithelial cells as part of the events precursors of oral carcinogenesis. (bvsalud.org)
  • It was not possible to verify the relation between histological grading of oral epithelial dysplasia and expression of Wnt-5a. (bvsalud.org)
  • Demethylation was successfully performed using 5'-Aza-2'deoxycytidine (5-Aza-dC) resulting in SOX11 mRNA and protein expression in a previously negative EOC cell line. (lu.se)
  • Here, live respiratory epithelial cells were inoculated with broth-grown or biofilm bacteria of different M-types, as well as with isogenic mutants lacking common virulence factors. (lu.se)
  • There was also no change in the production of tight junction proteins regardless of lactoferrin metal saturation status. (springer.com)
  • Furthermore, LPS-triggered partial disruption of epithelial integrity was reduced after FWGE application. (hindawi.com)
  • Although IFN-β promotes apoptosis, IFN-α activates specific antiapoptotic target genes whose actions preserve epithelial barrier integrity. (elsevierpure.com)
  • We have recently identified guanylate binding protein-1 (GBP-1) as an antiapoptotic protein, regulated by both type I and type II IFNs, that promotes intestinal epithelial barrier integrity in mature intestine. (elsevierpure.com)
  • Determining the transepithelial electrical resistance and paracellular permeability of Caco-2 monolayer/macrophage co-cultured system suggested that the OJPs-loaded nanoparticles effectively protected the intestinal epithelial barrier integrity against the damage caused by LPS-stimulated macrophage inflammation and attenuated the defects of intestinal epithelial TJ barrier and permeability. (tmu.edu.tw)
  • The rate-limiting constituent of collecting duct sodium transport is the epithelial sodium channel (ENaC). (portlandpress.com)
  • Further in vitro studies revealed that CK2 activity promotes epithelial restitution, and protects normal IECs from cytokine-induced apoptosis. (diva-portal.org)
  • However, the mechanisms by which commensal bacteria regulate epithelial apoptosis during colonization of immature intestine and the contributions of GBP-1 are unknown. (elsevierpure.com)
  • The recombinant nacrein protein inhibited the precipitation of calcium carbonate from a saturated solution containing CaCl 2 and NaHCO 3 , indicating that it can act as a negative regulator for calcification in the shells of molluscs. (bioone.org)
  • Hiroshi Miyamoto , Fumiko Miyoshi , and Jun Kohno "The Carbonic Anhydrase Domain Protein Nacrein is Expressed in the Epithelial Cells of the Mantle and Acts as a Negative Regulator in Calcification in the Mollusc Pinctada fucata ," Zoological Science 22(3), 311-315, (1 March 2005). (bioone.org)
  • Guinea pig primary peripheral lung epithelial cells (PLECs) transfected with adenovirus E1A (E1A-PLECs) were compared to guinea pig normal lung fibroblasts (NLFs) transfected with E1A (E1A-NLFs). (ersjournals.com)
  • Adenoviral DNA is retained by peripheral epithelial cells of the lung (PLECs) in humans in whom the viral E1A gene is expressed 4 without replication of a complete virus 5 . (ersjournals.com)
  • The aim was to evaluate that whether EMT-related proteins' alterations are associated with clinicopathological features and prognosis in lung adenocarcinoma. (biomedcentral.com)
  • The number of EMT-related proteins' alteration is a significant prognostic marker to predict overall survival in patients with lung adenocarcinoma. (biomedcentral.com)
  • The aim was to evaluate changes in EMT-related protein and to investigate their association with clinicopathological parameters and prognosis in lung adenocarcinoma. (biomedcentral.com)
  • 2. The aim of this work was to investigate how hypoxia affects human lung epithelial cells in combination with profibrotic stimuli and its correlation to pathogenesis. (lu.se)
  • By virtue of expressions of glial and neural surface markers and capability of neurotransmitter metabolism, amniotic epithelial cells are considered as candidate cell type for transplantation strategies to treat neurological disorders. (scielo.org.ar)
  • Appropriate microbial colonization protects the developing intestine by promoting epithelial barrier function and fostering mucosal tolerance to luminal bacteria. (elsevierpure.com)
  • Therefore, the main objective of this study was to elucidate how iron-depleted, iron-saturated, and manganese-saturated forms of lactoferrin regulate intestinal barrier function via interactions with epithelial cells and macrophages. (springer.com)
  • Epithelial cell counts in BAL after Cl2 exposure were greater in TCR-delta-/- mice, but macrophages showed a later peak and granulocyte numbers were lower in TCR-delta-/- than in wild type mice. (cdc.gov)
  • some is secondarily produced by alveolar macrophages and epithelial cells. (msdmanuals.com)
  • High temperature protein G (HtpG), a gene encoding a bacterial HSP, is less abundant in pediatric CD patients than in healthy individuals. (dal.ca)
  • In Drosophila , the function of grainyhead (grh) gene is essential during developmental processes such as epithelial differentiation, tracheal tube formation, maintenance of wing and hair polarity, and epidermal barrier wound repair. (bvsalud.org)
  • Furthermore, investigations focusing on the epithelial-specific activation of grh and GRHL factors have revealed that these factors potentially act as a pioneer factor in establishing a cell -type/ cell - state specific accessible chromatin landscape that is exclusive for epithelial gene transcription. (bvsalud.org)
  • What does this gene/protein do? (cancerindex.org)
  • Results showed that in cultured human-derived retinal pigment epithelial ARPE-19 cells , the extract of Chlorella zofingiensis and its nutritional ingredient astaxanthin exhibited significant inhibitory effects on the formation of endogenous N ε -carboxymethyllysine (CML), a key AGE representative, through the suppression of intracellular oxidative stress. (rsc.org)
  • Using RNA-Seq, we identified a total of 163 and 568 differentially expressed genes in primary normal human bronchial epithelial (NHBE) cells that were exposed to diacetyl and 2,3-pentanedione, respectively. (nature.com)
  • In this study, we utilized primary normal human bronchial epithelial (NHBE) cells that are cultured at an air-liquid interface (ALI) to mimic the in vivo airway characteristics 30 . (nature.com)
  • Identification of Key Proteins in Human Epithelial Cells Responding to" by Hayley Furlong, Richard Smith et al. (tudublin.ie)
  • Human epididymis protein 4 (HE4) appears to have similar diagnostic performance as CA-125 [ 3 ], but is currently only approved for monitoring women with EOC for disease recurrence or progression. (biomedcentral.com)
  • Confluent NCI-H292 human mucoepidermoid airways epithelial cells were pretreated with AZM or MDM for 2 h and then stimulated with 200 nmol/l phorbol 12-myristate 13-acetate (PMA) for 8 h. (karger.com)
  • Nanopore Sequencing Unveils Diverse Transcript Variants of the Epithelial Cell-Specific Transcription Factor Elf-3 in Human Malignancies. (nih.gov)
  • Previously, we have reported neurotrophism exhibited by human amniotic epithelial cells when transplanted after spinal cord injury in bonnet monkeys. (scielo.org.ar)
  • The effects of corticosteroids are predominantly mediated by the inhibition of NF-κB deoxyribonucleic acid (DNA)-binding activity, which controls genes encoding inflammatory cytokines, chemokines and adhesion molecules in respiratory epithelial cells 10 - 13 . (ersjournals.com)
  • In this study, the protective effect of a fermented wheat germ extract (FWGE) against LPS-induced inflammation and oxidative stress in IPEC-J2 porcine intestinal epithelial cells was studied. (hindawi.com)
  • In addition, chronic diagnostic test for follow-up of patients cy and for biochemical determination inflammation associated with the infec- with H. pylori gastritis and were able of tissue COX-2 activity using COX tion leads to damage in proteins, the to predict the risk of development of Activity Assay Kit (Cayman Chemical production of reactive oxygen species stomach cancer. (who.int)
  • This necessitates the investigation of past experimental approaches in their attempt to correlate oxidative stress and ocular diseases in humans in both the epithelial cells plus the capsule (LECs/capsule) and in the aqueous humor (AH). (molvis.org)
  • One class of proteins with high potential as oncologic biomarkers are cancer-testis antigens (CTAs). (biomedcentral.com)
  • Recently, our conclusion of usefulness of amniotic epithelial cells transplantation to treat spinal cord injuries has been confirmed in rodent models of spinal cord injury (Zhi-yuan et al. (scielo.org.ar)
  • CONCLUSION: The severity of airway epithelial injury after Cl2 is greater in TCR-delta-/- mice but the inflammatory response and the change in airway responsiveness to methacholine are reduced. (cdc.gov)
  • We examined the abundance of ENaC subunit mRNAs and proteins in puromycin aminonucleoside (PAN)-induced nephrotic syndrome. (portlandpress.com)
  • The proteomic changes measured in HaCaT cells receiving the ITCM revealed that exposure to 0.5 Gy induced an upregulation of annexin A2 and cingulin and a downregulation of Rho-GDI2, F-actin-capping protein subunit beta, microtubule-associated protein RP/EB family member, and 14-3-3 proteins. (tudublin.ie)
  • The 0.1 Gy dose also induced a downregulation of Rho-GDI2, hMMS19, F-actin-capping protein subunit beta, and microtubule-associated protein RP/EB family member proteins. (tudublin.ie)
  • So how can the Wireless protein work/regulate Rho1 activity at junctions? (biologists.com)
  • Its junctional enrichment is controlled by the G proteins Gβ13F/Gγ1, previously found to regulate medio-apical and junctional Myosin II. (biologists.com)
  • Protein markers commonly used for circulating tumor cells investigations. (medscape.com)
  • These proteins' alteration was associated with poor cell differentiation and poor patients' outcome, respectively. (biomedcentral.com)
  • At this juncture, through the present study it was found that, chicken neural retinal cells when grown alone failed to survive and contrarily when either co-cultured with chicken amniotic epithelial cells / cultured in amniotic epithelial cell conditioned medium not only survived but also showed extensive differentiation. (scielo.org.ar)
  • While abnormal keratin filament structure and function can explain hypohidrosis and epithelial differentiation abnormalities, the absence of dermatoglyphics is not well understood. (medscape.com)
  • Addition of a GPI anchor to the ectodomain of Herpes simplex gD-1, secreted without polarity, led to basolateral localization of the fusion protein, gD1-DAF. (rupress.org)
  • The slow rate of change of protein carbonyls strongly suggests a long-term implication of OS in ocular disease pathogenesis. (molvis.org)
  • the remaining patients are probably able to degrade the abnormal protein, although the exact protective mechanism is unclear. (msdmanuals.com)
  • Here, we use primary nasal epithelial cells (NECs) from children and adults, differentiated at an air-liquid interface to show that the ancestral SARS-CoV-2 replicates to significantly lower titers in the NECs of children compared to those of adults. (plos.org)
  • A higher number of EMT-related proteins' alteration was found to be significantly associated with unfavorable outcome. (biomedcentral.com)
  • Metabolic activity was significantly increased by hypoxia in both epithelial cell types. (lu.se)
  • CheKine™ microquantitative test kits and recombinant proteins help you explore cells with ease! (abbkine.com)
  • It was concluded that circulating epithelial cells may be present in patients with benign inflammatory colon which were detectable by CTC assays. (medscape.com)
  • Alternatively, indirect methods for assessing oxidative stress have been applied and focus mainly on the oxidative damage ROS cause in biomolecules, such are lipids, proteins, and DNA. (molvis.org)