Protein and gene lipid transfer proteins carrier proteins. Medical search. Frequent questions

Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate Golgi functionality. (tamu.edu)
An interface coordinating lipid metabolism with proteins that regulate membrane trafficking is necessary to regulate Golgi morphology and dynamics. (tamu.edu)
Importantly, Sec14 and Sec14-like proteins are a unique superfamily of proteins that sense specific aspects of lipid metabolism, employing this information to potentiate phosphoinositide production. (tamu.edu)
Therefore, Sec14 and Sec14 like proteins form central conduits to integrate multiple aspects of lipid metabolism with productive phosphoinositide signaling. (tamu.edu)
The CYS-3 transcription factor bound the promoters and regulated genes involved in sulfur metabolism. (escholarship.org)
During sulfur starvation, genes involved in nitrogen metabolism, such as amino acid and nucleic acid metabolic pathways, along with genes encoding proteases and nucleases that are necessary for scavenging nitrogen, were activated. (escholarship.org)
Sulfur starvation also caused changes in the expression of genes involved in carbohydrate metabolism, such as those encoding glycosyl hydrolases. (escholarship.org)
Along with genes involved in sulfur metabolism, this transcription factor regulated a number of uncharacterized transporter genes and genes involved in mitochondrial electron transfer. (escholarship.org)
Hooper AJ, van Bockxmeer FM, Burnett JR. Monogenic hypocholesterolaemic lipid disorders and apolipoprotein B metabolism. (medlineplus.gov)
Microsomal triglyceride transfer protein expression in adipocytes: a new component in fat metabolism. (medlineplus.gov)
In recent decades, many lipid metabolism genes and pathways have been identified, but the molecular mechanisms that underlie species differences in seed oil biosynthesis are not fully understood. (researchsquare.com)
Compared to rapeseed and castor bean, fewer lipid biosynthesis genes but more lipid metabolism genes were regulated in the maize embryo. (researchsquare.com)
This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. (fn-test.com)
These genes increase oxygen availability by inducing erythropoiesis and angiogenesis, and also reduce its demand via regulation of energy metabolism by reducing oxidative phosphorylation and inducing non-oxygen-demanding glycolysis [ 5 , 6 , 7 ]. (springer.com)
Our data suggests that TMEM106B is one of a growing list of major dementia risk genes that affect glial lipid metabolism. (biomedcentral.com)
these apolipoproteins have lipid-soluble segments, the beta apolipoproteins, which remain part of the lipoprotein throughout its metabolism. (medscape.com)
Such reactions are involved in carbohydrate, protein and lipid metabolism as well as in the metabolic conversion of vitamins B 6 and B 9 into their biologically active forms [ 1 ]. (biomedcentral.com)
Endothelial lipase (EL) is a major determinant of high-density lipoprotein-cholesterol (HDL-C) metabolism, but the association of endothelial lipase gene ( LIPG ) polymorphism and serum HDL-C levels is scarce and conflicting in diverse populations. (biomedcentral.com)
Key proteins involved in lipoprotein metabolism, such as PCSK9, angiopoietin-related protein 3, cholesteryl ester transfer protein and apolipoprotein(a), have been identified as viable targets for therapeutic intervention through observational and genetic studies. (cdc.gov)

this mutation replaces the protein building block (amino acid) glycine with a premature stop signal at position 865 (written as Gly865Ter or G865X) in the instructions used to make the microsomal triglyceride transfer protein. (medlineplus.gov)
In addition, recent placental epithelial transcriptome analysis identified several glucose, amino acid, lipid, vitamin, mineral and hormone transporter mechanisms within the placenta. (biomedcentral.com)
This single-chain 535 amino acid long protein causes the symptoms of acute diphtheria infection. (org.ua)

Sterol carrier protein-2 ( SCP-2) is an intracellular, small, basic protein domain that in vitro enhances the transfer of lipids between membranes. (slu.se)
[ 4 ] Protein hZIP4 transports zinc ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, where it is available to other newly synthesized proteins. (medscape.com)
Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. (fn-test.com)
MTP mediates intracellular lipid transport in the intestine and liver and thus ensures the normal function of chylomicrons (CMs) in enterocytes and of VLDL in hepatocytes. (medscape.com)

The MTTP gene provides instructions for making a protein called microsomal triglyceride transfer protein. (medlineplus.gov)
Most MTTP gene mutations lead to the production of microsomal triglyceride transfer protein with reduced or absent function, preventing the formation of beta-lipoproteins. (medlineplus.gov)
Gunduz M, Ozaydin E, Atar MB, Koc N, Kirsaclioglu C, Kose G, Cefalu AB, Averna M, Tarugi P. Microsomal triglyceride transfer protein gene mutations in Turkish children: A novel mutation and clinical follow up. (medlineplus.gov)
Walsh MT, Di Leo E, Okur I, Tarugi P, Hussain MM. Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects. (medlineplus.gov)
It is caused by a homozygous autosomal recessive mutation in the gene for microsomal triglyceride transfer protein (MTP). (medscape.com)

The genes encoding non-specific lipid transfer proteins (nsLTPs), members of a small multigene family, show a complex pattern of expressional regulation, suggesting that some diversification may have resulted from changes in their expression after duplication. (korea.ac.kr)
Additionally, CYS-3 directly activated the expression of a number of uncharacterized transporter genes, suggesting that regulation of sulfur import is an important aspect of regulation by CYS-3. (escholarship.org)
Telomerase is excessively activated in most of tumors and is involved in the regulation of cell cycle proteins, such as p16Ink4a and p21WAF1, which induce epithelial cell apoptosis [7]. (docksci.com)
In castor bean, we observed differential regulation of vital oil biosynthetic enzymes and extremely high expression levels of oil biosynthetic genes, which were consistent with the rapid accumulation of oil in castor bean developing seeds. (researchsquare.com)
This process allows a variety of important applications, including the study of gene regulation, the analysis of the expression of proteins within eukarotic cells such as those of mammals, the production of transgenic organisms , and the methods of gene therapy. (newworldencyclopedia.org)
Understanding gene function and regulation requires rigorous testing in live cells and organisms. (cshlpress.com)
These include viral and nonviral methods of gene delivery, transgenic approaches, strategies for the regulation of transgene expression, and modification of the host response. (cshlpress.com)

The exact molecular mechanism of C-domain transport across the lipid bilayer is unknown but it is known that T-domain is strongly involved in this process. (org.ua)

HSD17B4, SCPX, HSDL2, and STOML1 encode fusion proteins with SCP-2 downstream of another protein domain, whereas C20orf79 encodes an unfused SCP-2. (slu.se)
HSD17B4 which encodes a D-bifunctional protein ( DBP) with domains for D-3-hydroxyacyl-CoA dehydrogenase, enoyl-CoA hydratase, and SCP-2 are found in animals from insects to mammals and also in fungi. (slu.se)
The DOLK gene encodes dolichol phosphate (DOLK), an enzyme that catalyzes the transfer of a phosphate molecule onto dolichol following dolichol biosynthesis. (cdghub.com)
The DOLK gene encodes the enzyme dolichol kinase (DOLK), which is also called DK1. (cdghub.com)
The SLC30A2 gene encodes a zinc transporter, ZnT2. (medscape.com)
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2) , as a result of transcription initiation from 2 independently regulated promoters. (fn-test.com)
The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. (fn-test.com)
Encodes a protein predicted to act as a carboxylesterase. (or.jp)

To solve the problems of low siRNA transfection efficiency and degradation by nucleases, we used Lipid-polycation-nucleic acid (LPN) complex nanocarrier vectors. (docksci.com)
Many existing tissue-engineering approaches focus on delivery of selected proteins (growth factors, transcription factors etc.) or nucleic acids to host or implanted stem cells to achieve lineage specific differentiation. (frontiersin.org)
Gene Transfer: Delivery and Expression of DNA and RNA provides the first comprehensive guide to technical approaches for delivering nucleic acids into cells and organisms and of ensuring (even manipulating) appropriate expression. (cshlpress.com)
Exosomes have gradually become the focus of research, exosomes are rich in nucleic acids and proteins, including a large amount of microRNAs. (imrpress.com)
EVs are a natural carrier system that can transfer nucleic acids, proteins, and lipids between donor and recipient cells in an autocrine, paracrine, and endocrine manner. (imrpress.com)

All MTTP gene mutations that cause abetalipoproteinemia impair beta-lipoprotein formation and result in a severe shortage of chylomicrons, LDLs, and VLDLs. (medlineplus.gov)
Each lipoprotein is characterized by its lipid composition and by the type and number of apolipoproteins it possesses. (medscape.com)

DOLK catalyzes the transfer of phosphate from cytidine triphosphate (CTP) to dolichol following biosynthesis of dolichol, generating dolichol phosphate (Dol-P). Dol-P is a lipid carrier of the oligosaccharide precursor in N-glycosylation and as a donor of glucose and mannose for several glycosylation pathways 1,2,8,12 . (cdghub.com)
Therefore, Bmi-1 and hTERT may inhibit apoptosis through different pathways and affect the expression levels of other genes in return. (docksci.com)
They play a crucial role in cell-based assays in drug discovery , focusing on signaling pathways, gene expression , among other endpoints. (marinbio.com)

CYS-3 also directly regulated the expression of genes involved in mitochondrial electron transfer. (escholarship.org)
These mitochondrial responses are governed by general principles of regulatory biology exemplified by changes in gene expression, protein translation, protein complex formation, transmembrane transport, enzymatic activities and metabolite levels. (nature.com)
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese. (nature.com)
Now, a variety of genes that cause mitochondrial disease have been discovered. (medlink.com)
Reducing equivalents produced in the Krebs cycle and in the beta-oxidation spirals are passed along a series of protein complexes embedded in the inner mitochondrial membrane (the electron transport chain). (medlink.com)

LLO) and the 14-sugar oligosaccharide is transferred onto asparagine (N) residues of newly synthesized proteins in the ER lumen. (cdghub.com)
We used comparative protein-structure modelling to predict residues that interact with two amino acids known to be critical for hRFVT-2 function (the clinical mutants L123 and L339), site-directed mutagenesis, and truncation approach in the human-derived brain U87 cell model. (biomedcentral.com)
These investigations report on identification of residues/sequences in the hRFVT-2 protein that is important for its physiological function and cell biology. (biomedcentral.com)
Our aim in this study was to expand our knowledge in these areas, and we used a comparative protein-structure modelling to predict residues that interact with two amino acids known to be critical for hRFVT-2 function, i.e. (biomedcentral.com)

Such an interface facilitates the membrane deformations required for vesicularization, forms platforms for protein recruitment and assembly on appropriate sites on a membrane surface and provides lipid co-factors for optimal protein activity in the proper spatio-temporally regulated manner. (tamu.edu)
Dolichol is a lipid that can be found in the membrane of the ER and is important for glycosylation in two ways: it acts a lipid carrier for the 14-sugar oligosaccharide that is transferred onto nascent proteins during N-glycosylation and is a monosaccharide donor of mannose and glucose sugars for N-glycosylation, O- and C-mannosylation and GPI anchor biosynthesis (Figure 1) 8,13 . (cdghub.com)
[ 3 ] This protein controls zinc uptake across the plasma membrane of various cell types, including the intestine. (medscape.com)
In addition to electroporation, transfection can be carried out using calcium phosphate, or by mixing a cationic lipid with the material to produce liposomes, which fuse with the cell plasma membrane and deposit their cargo inside. (newworldencyclopedia.org)
B-subunit is composed of two domains: receptor domain or R-domain, which is responsible for binding to cell DT receptor, and transmembrane or T-domain, which is involved in the process of C-domain transfer in the cytosol across endosomal membrane. (org.ua)
Truncating the N- and C- terminals of hRFVT-2 led to significant inhibition in RF uptake, which was associated with changes in protein stability/translation efficiency (it was also associated with a partial impairment in membrane targeting in the case of the N-terminal truncation). (biomedcentral.com)

Mutations in the DOLK gene reduce the availability of dolichol, leading to proteins with abnormal sugar chains. (cdghub.com)
More than 60 mutations in the MTTP gene have been found to cause abetalipoproteinemia. (medlineplus.gov)
Cancer is a multigene disorder that arises from gene mutations as well as changes in transcriptional, epigenetic, and proteomic profiles. (takarabio.com)

Sulfur is an important nutrient source found in a number of biological macromolecules, including proteins and lipids. (escholarship.org)
Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. (lookformedical.com)
Recent advances in cancer biology have highlighted the importance of exosomes as carriers of genetic and biological messages between cancer cells and their immediate and distant environments. (takarabio.com)
Cancer cells secrete exosomes containing diverse molecules that can be transferred to recipient cells and vice versa to induce a plethora of biological processes, including angiogenesis, metastasis formation, and therapeutic resistance. (takarabio.com)
In its biologically active forms, flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN), the vitamin plays key metabolic roles as an intermediate in the transfer of electrons in biological oxidation-reduction reactions. (biomedcentral.com)

Biosynthesis of dolichol is one of the first steps in glycosylation , where dolichol acts as a lipid carrier for the oligosaccharide precursor in the early stages of N-glycosylation of proteins. (cdghub.com)
These results shed light on molecular mechanisms of lipid biosynthesis in rapeseed, castor bean, and maize. (researchsquare.com)

This protein helps produce beta-lipoproteins, which are molecules that are made up of proteins (including one called apolipoprotein B), cholesterol, and particular types of fats called phospholipids and triglycerides. (medlineplus.gov)
Layers of lipid molecules which are two molecules thick. (lookformedical.com)
In anabolism, water is removed from molecules (through energy requiring enzymatic chemical reactions) in order to grow larger molecules (e.g. starches, triglycerides and proteins for storage of fuels and information). (hmdb.ca)
These assays not only measure the quantitative effects of drugs but are also crucial for evaluating DNA/RNA/protein/small molecules/nanoparticles in biology assays . (marinbio.com)
NF-κB is a transcription factor that plays a pivotal role in the highly specific pattern of gene expression observed for immune, inflammatory and acute phase response genes, including interleukin 1, interleukin 8, tumor necrosis factor and certain cell adhesion molecules. (justia.com)
Degradation of a protein via the ubiquitin pathway proceeds by two discrete and successive steps: (a) covalent attachment of multiple ubiquitin molecules to the protein substrate, and (b) degradation of the targeted protein by the 26S proteasome complex. (justia.com)

ANOVA was used to test the effect of major dementia risk alleles in the TMEM106B and APOE genes on the hippocampal proteome and lipidome, adjusting for age, gender, and post-mortem interval. (biomedcentral.com)
The increase in TMEM106B levels with ageing was specific to carriers of the rs1990622-A allele in the TMEM106B gene that increases risk for frontotemporal dementia, Alzheimer's disease, Parkinson's disease, and hippocampal sclerosis with ageing. (biomedcentral.com)
Hippocampal lipids were not significantly affected by APOE genotype, however levels of myelin-enriched sulfatides and hexosylceramides were significantly lower, and polyunsaturated phospholipids were higher, in rs1990622-A carriers after controlling for APOE genotype. (biomedcentral.com)

Transcriptome analyses showed that more than 61% of the lipid- and carbohydrate-related genes were regulated in rapeseed and castor bean, but only 20.1% of the lipid-related genes and 22.5% of the carbohydrate-related genes were regulated in maize. (researchsquare.com)

Second, altering the MSC state by inducing differentiation into multiple lineages did not affect the exosomal properties or endocytosis but triggered the expression of lineage-specific genes and proteins in vitro and in vivo respectively. (frontiersin.org)
Additionally, MarinBio specializes in in vitro cell-based assay testing services for clinical and pre-clinical studies, including method development, qualification, validation, transfer, lot-release testing, and potency testing according to guidelines from both FDA and International Council for Harmonization (ICH). (marinbio.com)
To enhance the osteogenic potential of stem cell sheet, we fabricated bone morphogenetic protein 2 ( BMP-2 ) gene-engineered cell sheet using a complex of polyethylenimine-alginate (PEI-al) nanocomposites plus human BMP-2 complementary(c)DNA plasmid, and studied its osteogenesis in vitro and in vivo. (dovepress.com)
The expression of osteogenesis-related gene was increased, which demonstrated that released BMP-2 could effectively induce the cell sheet osteogenic differentiation in vitro. (dovepress.com)

Introduction Tumor occurrence and development requires the activation of many pro-oncogenes and the inactivation of many tumor suppressor genes. (docksci.com)
P16INK4A and P19ARF (P14ARF in humans) are two tumor suppressor genes encoded by INK4a-ARF and inhibited by Bmi-1. (docksci.com)
EGFR , HER2 , KRAS ) and tumor suppressor genes (e.g. (takarabio.com)
The molecular profiles gathered from circulating tumor DNA (ctDNA) can be further complemented with those obtained through analysis of circulating tumor cells (CTCs), as well as RNA, proteins, and lipids contained within cell-derived vesicles, such as exosomes. (takarabio.com)

During sulfur starvation, the transcription factor CYS-3 is responsible for upregulation of genes involved in sulfur uptake and assimilation. (escholarship.org)
We also used DNA affinity purification sequencing to identify the direct downstream targets of the transcription factor responsible for regulating genes involved in sulfur uptake and assimilation. (escholarship.org)
Galactosylated lipid substances allowed liver specific uptake of AZT at enhanced parenchymal: non-parenchymal selectivity ratios and at the same time could deliver MCZ for treatment of fungal infections. (ijpsr.com)

Our study demonstrates that TMEM106B protein abundance is increased with brain ageing in humans, establishes that dementia risk allele rs1990622-A predisposes to TMEM106B fibril formation in the hippocampus, and provides the first evidence that rs1990622-A affects brain lipid homeostasis, particularly myelin lipids. (biomedcentral.com)

Changes in gene expression and apoptosis rate were measured by flow cytometry. (docksci.com)
The expression level of Bmi-1 and hTERT was decreased by the gene silencing of either Bmi-1 or hTERT, but the effects were more significant when both were silenced simultaneously. (docksci.com)
We, therefore constructed an in frame deletion mutant of dltX , without affecting the expression of the other genes of the operon. (frontiersin.org)
Moreover, for genes that are expressed in multiple tissues or at multiple stages of development, the use of tissue-specific expression of the Cre recombinase allows gene function to be perturbed in specific cell types and/or at specific times. (elifesciences.org)

Once dolichol is generated, it must be phosphorylated by the enzyme dolichol kinase (DOLK), generating dolichol-phosphate (Dol-P) before it can be used as a lipid carrier or monosaccharide donor 8,12 . (cdghub.com)

More importantly, most maize genes encoding lipid-related transcription factors, triacylglycerol (TAG) biosynthetic enzymes, pentose phosphate pathway (PPP) and Calvin Cycle proteins were not regulated during seed oil synthesis, despite the presence of many homologs in the maize genome. (researchsquare.com)
This leads to an almost complete arrest of protein synthesis in the cell and its death. (org.ua)

Sulfur is an important nutrient source found in proteins, lipids, and electron carriers that are required for the survival of filamentous fungi such as Neurospora crassa. (escholarship.org)
The electron transport chain consists of 4 multimeric complexes (I to IV) plus 2 small electron carriers, coenzyme Q10 (or ubiquinone) and cytochrome c . (medlink.com)

In a nursing mother, this effectively decreases the zinc transfer from serum to breast milk, producing a transient zinc deficiency in an exclusively breastfed child. (medscape.com)
Using a combination of parabiosis and serum transfer experiments, we find evidence supporting the hypothesis that Cre may be trafficked from its cell of origin to the epididymis through the circulatory system. (elifesciences.org)
T (rs2000813) polymorphism and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations. (biomedcentral.com)
The T allele carriers had higher serum HDL-C and TC levels than the T allele noncarriers. (biomedcentral.com)
Serum lipid parameters were also correlated with several environmental factors in the both ethnic groups. (biomedcentral.com)

Amazingly, given the long history of vaccine use and promotion, the full characterization of what proteins it contains, and where they are derived from, was never previously performed. (wakingtimes.com)
Recent advances have been made in the of host factors, polymorphisms, and candidate genes associated characterization of the immune response to low-molecular- with occupational asthma may improve our understanding of weight agents. (cdc.gov)

FHBL is caused by an autosomal, codominant mutation in the gene for apoB ( APOB ), which is carried on chromosome 2. (medscape.com)
For example, in Timothy Syndrome the mutation in the gene produces too much of the protein, in this case the L-type calcium channel Cav1.2. (epiphanyasd.com)

The gene SLC39A4 was found to encode a solute carrier protein called human zinc/iron-regulated transporterlike protein (hZIP4). (medscape.com)

Compared to oil seed (rapeseed and castor bean), less oil biosynthetic genes were regulated during the seed development in non-oil seed (maize). (researchsquare.com)

For most applications of transfection, it is sufficient if the transfected gene is only transiently expressed. (newworldencyclopedia.org)
If it is desired that the transfected gene actually remains in the genome of the cell and its daughter cells, a stable transfection must occur. (newworldencyclopedia.org)
The development of commercially available transfection reagents for gene transfer applications has revolutionized the field of molecular biology and scientific research. (mdpi.com)

Genetic material, such as sections of DNA coding for proteins , may be transfected. (newworldencyclopedia.org)
The named and biochemical disorders may or may not have been caused by their initially described genetic variation, but potentially by other gene variations. (medlink.com)

These proteins can be targeted using a variety of approaches, such as protein inhibition or interference, inhibition of translation at the mRNA level. (cdc.gov)

Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. (fn-test.com)
Modulating agents include human E3 ubiquitin ligases, antibodies thereto and variants thereof, as well as related proteins. (justia.com)
Variants in blood pressure genes and the risk of Accardi R, Rubino R, Scalise M et col . (2011). (who.int)

These particles consist of a core of cholesterol esters and triglycerides surrounded by a monolayer of free cholesterol, phospholipids, and proteins (apolipoproteins). (medscape.com)

events have receptors stimulated with students( GAGs), unregulated chains docking of a inactive actin, all of an been protein respiration cell a considerable subunits. (evakoch.com)

Specific protein-binding measures are often used as assays in diagnostic assessments. (lookformedical.com)
Click Gene ID to show a list of GSM assays in which the gene are specifically expressed. (or.jp)

The development of tools to manipulate the mouse genome, including knockout and transgenic technology, has revolutionized our ability to explore gene function in mammals. (elifesciences.org)

The cytotoxic action of DT is mediated by catalytic transfer of ADP-ribosyl group from NAD + to the diphthamide residue (modified histidine residue) in eukaryotic translation elongation factor 2 (eEF-2). (org.ua)

In this syndrome Nav1.8 is over expressed as a downstream consequence of a mutation in the TCF4 gene. (epiphanyasd.com)

Pig conceptuses are fructogenic, such that a substantial portion of glucose transferred from mother to fetus is converted to fructose. (biomedcentral.com)

On the other hand, DT represents a very interesting molecular machine which allows using this protein in different bioengineering applications, such as ablation of certain cell types in transgenic mice, development of immunotoxins targeted for specific cell markers and also for delivery of certain proteins into the cytosol. (org.ua)

While some with the highest LDL-C are diagnosed with HoFH in childhood, many others are missed, denying them the opportunity for timely initiation of aggressive lipid-lowering therapies (LLT) and resulting in premature cardiovascular disease. (cdc.gov)

The term transformation often is preferred to describe non-viral DNA transfer in bacteria and non-animal eukaryotic cells such as fungi , algae , and plants . (newworldencyclopedia.org)
A variety of extracellular stimuli including mitogens, cytokines, antigens, stress inducing agents, UV light and viral proteins initiate a signal transduction pathway that ultimately leads to NF-κB release and activation. (justia.com)

Bmi-1 (B cell-specific Moloney leukemia virus integration site-1) was the first gene discovered in the polycomb protein family, and it plays an important role in cell immortalization and differentiation and embryonic stem cell development [1]. (docksci.com)
Our chemistry has been optimized to work efficiently with blood samples and is compatible with leading target enrichment platforms for whole-exome sequencing or specific gene panels. (takarabio.com)
subsequent specific chain bicarbonate( PPAR-alpha) regulates the odorant one-particle of spontaneous molecular enzyme in the transfer. (evakoch.com)
This event has been known for quite some time to occur via a specific and carrier-mediated process, but the molecular identity of the system (s) involved has only been recently uncovered. (biomedcentral.com)

The genomic distribution of the nsLTP genes in the rice genome differs from that in wheat. (korea.ac.kr)

Zinc stabilizes cell membranes by reducing free radicals and preventing lipid peroxidation. (medscape.com)
To further test the osteogenic potential of the cell sheet in vivo, enhanced green fluorescent protein or BMP-2-producing cell sheets were treated on the cranial bone defects. (dovepress.com)
Our results suggested that PEI-al nanocomposites efficiently deliver the BMP-2 gene to bone marrow mesenchymal stem cells and that BMP-2 gene-engineered cell sheet is an effective way for promoting bone regeneration. (dovepress.com)
Recently, stem cell- and gene-based therapy has been applied in BTE and achieved some good clinical results. (dovepress.com)
Cell 75:495, 1993), and a series of unique E6-AP homologous proteins have been identified (Huibregtse et al. (justia.com)
Besides that, there is little known about structural features of the hRFVT-2 protein that are important for its function and cell biology. (biomedcentral.com)

E7 from human papil omavirus type 16 cooperate to cancer: the European prospective investigation into doi:10.1093/carcin/bgp321 PMID:20047954 target the PDZ protein Na/H exchange regulatory cancer and nutrition study. (who.int)

These repeats can drive at least three consistent unliganded containing proteins processing on which organizations they are. (evakoch.com)

Anatomy20

Organisms18

Diseases7

Chemicals and Drugs133

Analytical, Diagnostic and Therapeutic Techniques and Equipment28

Psychiatry and Psychology1

Phenomena and Processes46

Technology, Industry, Agriculture7

Information Science4

Health Care4

Metabolism19

Amino acid3

Intracellular4

Microsomal triglyc5

Regulation7

Bilayer1

Encodes8

Nucleic5

Lipoprotein2

Pathways3

Mitochondrial5

Residues4

Membrane6

Mutations3

Biological5

Biosynthesis2

Molecules6

Hippocampal3

Transcriptome1

Vitro4

Tumor4

Uptake3

Humans1

Expression4

Donor1

Synthesis2

Electron2

Serum5

Characterization2

Mutation in the gene2

Encode1

Biosynthetic1

Transfection3

Genetic2

MRNA1

Variants3

Phospholipids1

Subunits1

Assays2

Mammals1

Catalytic1

Downstream1

Glucose1

Transgenic1

Initiation1

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Specific4

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Cell6

PMID1

Consistent1