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AntibodiesAntibody SpecificityAntibodies, MonoclonalGTP-Binding Protein alpha SubunitsAntibodies, ViralCCAAT-Enhancer-Binding Protein-alphaAntibodies, BacterialMolecular Sequence DataAmino Acid SequenceAntibody FormationFluorescent Antibody TechniqueAntibodies, NeutralizingCross ReactionsBase SequenceEpitopesRabbitsBlotting, WesternAntibody AffinityImmunohistochemistryElectrophoresis, Polyacrylamide GelRecombinant ProteinsImmunoblottingMolecular WeightCloning, MolecularAntibodies, Anti-IdiotypicCell LineBinding Sites, AntibodyGTP-Binding Proteinsalpha 1-AntitrypsinEnzyme-Linked Immunosorbent AssayGTP-Binding Protein alpha Subunit, Gi2Immune SeraGTP-Binding Protein alpha Subunits, Gq-G11Mice, Inbred BALB CAntibodies, ProtozoanCells, CulturedImmunoglobulin GProtein BindingRecombinant Fusion ProteinsAntigens, CD47GTP-Binding Protein alpha Subunits, GsAntibodies, NeoplasmCattleKineticsHIV AntibodiesImmunoenzyme TechniquesNeutralization TestsSequence Homology, Amino AcidHeterotrimeric GTP-Binding ProteinsAntigen-Antibody ComplexImmunoglobulin MAntibodies, AntinuclearRNA, MessengerPeptide FragmentsFluorescent Antibody Technique, IndirectAntibodies, FungalTransfectionAutoantibodiesGTP-Binding Protein alpha Subunits, Gi-GoMembrane ProteinsEpitope MappingBinding SitesChromatography, AffinityAntigen-Antibody ReactionsGene ExpressionCell MembraneCarrier ProteinsMacromolecular SubstancesImmunologic TechniquesMicroscopy, ImmunoelectronCCAAT-Enhancer-Binding ProteinsDNA, ComplementaryImmunoassayImmunoglobulin Fab FragmentsDNASignal TransductionBinding, CompetitiveGlycoproteinsMutationLiverImmunosorbent TechniquesTumor Cells, CulturedReceptors, ImmunologicReceptors, Adrenergic, alphaAntibodies, CatalyticMice, Inbred C57BLPrecipitin TestsGene Expression RegulationEscherichia coliImmunochemistryPeptidesLow Density Lipoprotein Receptor-Related Protein-1B-LymphocytesPolymerase Chain ReactionHypoxia-Inducible Factor 1, alpha SubunitAntibodies, BlockingDNA Primersalpha-MacroglobulinsHybridomasNuclear Proteins
RabbitReactivityMonoclonal antibodiesSpecificitySecondary antibodiesDetectsSubunitAntigenEndogenousThermo Fisher SciAssayCytoplasmicCatalogAntigensGoatWestern BlotConcentrationMembrane proteinSerumAntiserumReagentsHumanPeptidesApplicationsMolecularMouseKinaseSequenceTransmembrane proteinPrimaryAutoimmuneAminoReceptorBiologicalProductsType0.05SpikeGentaurGeneDownstreamClassificationAliquot
Rabbit21
  • Samples were incubated with HSPH1 polyclonal antibody (Product # PA5-77793) using a dilution of 1:100 (1 hour at RT) and followed by FITC Goat Anti-Rabbit (green) at a dilution of 1:50 (1 hour at RT). (thermofisher.com)
  • The antibody is a rabbit polyclonal antibody raised against ENO1. (uscnk.com)
  • HIF1 Alpha antibody LS-B495 is an unconjugated rabbit polyclonal antibody to HIF1 Alpha (HIF1A) (aa530-825) from mouse. (lsbio.com)
  • Polyclonal antibody raised in rabbit against the Cas9 nuclease (CRISPR-associated protein 9) using a recombinant protein. (diagenode.com)
  • Polyclonal antibody raised in rabbit against 5-Carboxylcytosine (5ca-CMP monophosphate) conjugated to BSA. (diagenode.com)
  • Polyclonal antibody raised in rabbit against Lachnospiraceae bacterium (Lb) Cpf1 (CRISPR from Prevotella and Francisella 1) using a recombinant protein. (diagenode.com)
  • Polyclonal antibody raised in rabbit against the C-terminus of the S. aureus Cas9 nuclease (CRISPR-associated protein 9) using a recombinant protein. (diagenode.com)
  • Polyclonal antibody raised in rabbit against CEBP Alpha (CCAAT/enhancer binding protein (C/EBP), alpha), using a KLH-conjugated synthetic peptide. (diagenode.com)
  • Polyclonal antibody raised in rabbit against human CBX2 (chromobox 2), using a synthetic peptide containing a sequence from the C-terminus of the protein1. (diagenode.com)
  • Polyclonal antibody raised in rabbit against human CHD1 (Chromodomain Helicase DNA Binding Protein 1), using a synthetic peptide containing a sequence from t. (diagenode.com)
  • For immunofluorescence analysis Jurkat cells were fixed and permeabilized for detection of endogenous PKC beta pT642 using Anti- PKC beta I (pT642) Recombinant Rabbit Polyclonal Antibody (Product # 711607, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (H+L) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). (thermofisher.cn)
  • Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. (thermofisher.cn)
  • While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. (thermofisher.cn)
  • Description: A Rabbit Polyclonal antibody against CPXCR from Human. (davincieuropeanbiobank.org)
  • Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CPXCR1 - middle region. (davincieuropeanbiobank.org)
  • This Met antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. (davincieuropeanbiobank.org)
  • We applied both human monoclonal anti-SARS-Cov-2 antibodies (spike protein, nucleoprotein) and rabbit polyclonal anti-SARS-Cov-2 antibodies (envelope protein, membrane protein) to 55 different tissue antigens. (frontiersin.org)
  • Product Description google Rabbit anti-Glial cell-derived neurotrophic factor receptor alpha-3 (GFR alpha-3) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen. (biosensis.com)
  • Product Description Rabbit anti-Glial cell-derived neurotrophic factor receptor alpha-3 (GFR alpha-3) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen. (biosensis.com)
  • Immunohistochemical staining of rat dorsal root ganglia using Rabbit antibody to to GFR alpha-3 (1-11): whole serum, catalogue no. (biosensis.com)
  • A UW-Madison researcher has developed a rabbit polyclonal antibody for methylated PKM2. (warf.org)
Reactivity10
  • 1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. (abbkine.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human C4 Binding Protein Alpha (C4BPa) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. (tissue-cell-culture.com)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human GA Binding Protein Transcription Factor Alpha (GABPa) in samples from serum, plasma, tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (therabio.org)
  • We sought to determine whether immune reactivity occurs between anti-SARS-CoV-2 protein antibodies and human tissue antigens, and whether molecular mimicry between COVID-19 viral proteins and human tissues could be the cause. (frontiersin.org)
  • This extensive immune cross-reactivity between SARS-CoV-2 antibodies and different antigen groups may play a role in the multi-system disease process of COVID-19, influence the severity of the disease, precipitate the onset of autoimmunity in susceptible subgroups, and potentially exacerbate autoimmunity in subjects that have pre-existing autoimmune diseases. (frontiersin.org)
  • Cross-reactivity occurs when amino acid sequence homology exists between a pathogen and self-tissue proteins ( 1 ). (frontiersin.org)
  • In this mechanism, antibodies formed against SARS-CoV-2 would also bind to human tissue proteins leading to autoimmune reactivity. (frontiersin.org)
  • In direct ELISAs, approximately 50% cross-reactivity with recombinant rat IL-1 alpha is observed and less than 2% cross-reactivity with recombinant human (rh) IL-1 alpha is observed. (rndsystems.com)
  • In Western blots, approximately 50% cross-reactivity with recombinant mouse (rm) Integrin alpha 5 is observed and less than 2% cross-reactivity with recombinant human Integrin alpha M, rmIntegrin alpha 2, rmIntegrin alpha 4, and rmIntegrin alpha E is observed. (rndsystems.com)
  • ATP5G1 (ATP Synthase, H+ Transporting, Mitochondrial F0 Complex, Subunit C1 (Subunit 9)) Peptide, used to block Anti-ATP5G1 Antibody reactivity. (creative-biolabs.com)
Monoclonal antibodies6
  • They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. (thermofisher.cn)
  • Very recently, human monoclonal antibodies were approved for use on patients with COVID-19. (frontiersin.org)
  • The human monoclonal antibodies used in this study are almost identical with these approved antibodies. (frontiersin.org)
  • Explore our solutions for multiple applications - vaccines, monoclonal antibodies, recombinant proteins, cell or gene therapy. (vwr.com)
  • UW-Madison researchers have developed three novel monoclonal antibodies that all have exceptional activity against human and mouse GATA2. (warf.org)
  • In this work, we evaluated a panel of 16 anti-BoNT/A monoclonal antibodies (mAbs) for their ability to inhibit the in vitro activity of BoNT/A1, /A2, and /A3 complex as well as the recombinant LC of A1. (cdc.gov)
Specificity3
  • This antibody has specificity for Human CD97. (thermofisher.cn)
  • Specificity Western blot analysis indicates a high level of specificity to GFR alpha-3 for this antiserum. (biosensis.com)
  • Sensitivity and specificity with blocking antibody level together is 99.6%, and hence they are the tests of choice. (medscape.com)
Secondary antibodies1
  • See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more. (lsbio.com)
Detects7
  • MRE11 Polyclonal Antibody detects endogenous levels of MRE11 protein. (abbkine.com)
  • Integrin β1 Polyclonal Antibody detects endogenous levels of Integrin β1 protein. (abbkine.com)
  • Detects IL‑1 alpha /IL‑1F1 in direct ELISAs and Western blots. (rndsystems.com)
  • Anti-Phospho-Insulin Receptor (Tyr960) specifically detects endogenous levels of phosphorylated insulin receptor-beta protein. (sputnic-group.ru)
  • Detects human Integrin alpha 5/CD49e in Western blots. (rndsystems.com)
  • [ 1 ] Therefore the reflex panel detects anti-acetylcholine receptor (blocking and binding) antibodies in the serum, if antibody level is greater than 0.4nmol/L, or antibody level is greater than 15% then modulating antibody is added. (medscape.com)
  • Electrophoresis often detects an M-protein and/or elevated serum free light chains. (msdmanuals.com)
Subunit1
  • The alpha 5 subunit, also known as CD49e and VLA-5 alpha subunit, forms a heterodimer with the Integrin beta 1 subunit (CD29). (rndsystems.com)
Antigen1
  • This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. (thermofisher.cn)
Endogenous1
  • Endogenous testosterone released from the sample by ANS (8-anilino-1-naphthalene sulfonic acid) and norgestrel competes with the added testosterone derivative labeled with ruthenium complex for the binding sites on the biotinylated antibody. (cdc.gov)
Thermo Fisher Sci3
  • The following product was used in this experiment: MC1 Receptor Polyclonal Antibody from Thermo Fisher Scientific, catalog # AMR-020-200UL. (thermofisher.com)
  • The following product was used in this experiment: HSP105 Polyclonal Antibody from Thermo Fisher Scientific, catalog # PA5-77793, RRID AB_2735933. (thermofisher.com)
  • The following product was used in this experiment: Phospho-PKC beta-1 (Thr642) Recombinant Polyclonal Antibody (24HCLC) from Thermo Fisher Scientific, catalog # 711607, RRID AB_2632980. (thermofisher.cn)
Assay3
Cytoplasmic3
  • KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. (fishersci.com)
  • cell lines, these transcripts are translated into immunodetectable cytoplasmic and nuclear protein. (justia.com)
  • Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by antibodies to nuclear and cytoplasmic antigens, multisystem inflammation, protean clinical manifestations, and a relapsing and remitting course. (medscape.com)
Catalog1
  • Proliferation elicited by Recombinant Mouse IL-1a/IL-1F1 (50 pg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse IL-1a/IL-1F1 Polyclonal Antibody (Catalog # AB-400-NA). (rndsystems.com)
Antigens4
  • We found that SARS-CoV-2 antibodies had reactions with 28 out of 55 tissue antigens, representing a diversity of tissue groups that included barrier proteins, gastrointestinal, thyroid and neural tissues, and more. (frontiersin.org)
  • We also did selective epitope mapping using BLAST and showed similarities and homology between spike, nucleoprotein, and many other SARS-CoV-2 proteins with the human tissue antigens mitochondria M2, F-actin and TPO. (frontiersin.org)
  • Antibodies The immune system consists of cellular components and molecular components that work together to destroy antigens (Ags). (msdmanuals.com)
  • or toxic light chains secreted by the malignant plasma cells): Some M-proteins show antibody activity against self-antigens. (msdmanuals.com)
Goat2
  • BULK QUANTITIES of 1,000 mg single lot sizes of Polyclonal Antibody goat anti-human C-Reactive Protein (CRP). (leebio.com)
  • Alkaline phosphatase-conjugated anti-goat IgG secondary antibody is used according to the manufacturer's instructions. (eaglebio.com)
Western Blot4
  • Western Blot: ROR alpha/NR1F1 Antibody [NBP1-52813] - Western blot analysis of RORa expression in NP tissues isolated from three rats showed positive expression of the protein. (novusbio.com)
  • Western Blot: ROR alpha/NR1F1 Antibody [NBP1-52813] - HepG2 cell lysate, concentration 1.25ug/ml. (novusbio.com)
  • Various lysates were subjected to SDS PAGE followed by western blot with 21991-1-AP (PKC alpha antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. (ptglab.com)
  • WESTERN BLOT: Specific for the GST mu form (in rat and human) and does not cross-react with alpha or pi class GST's. (eaglebio.com)
Concentration2
  • Antibody concentration 10 ug/ml. (lsbio.com)
  • The binding sites of the labeled antibody become occupied partly by the sample analyte (depending on its concentration) and partly by the ruthenium-labeled hapten to form the respective immunocomplexes. (cdc.gov)
Membrane protein4
  • Elabscience Category Type: Polyclonal Synonyms: 2019-nCoV E protein, 2019-nCoV sM protein, Envelope small membrane protein. (proteomecommons.org)
  • The GLUT2 facilitated glucose transporter isoform is a membrane protein present in the pancreatic .beta. (justia.com)
  • The coronavirus genome encodes a spike protein, an envelope protein, a membrane protein, and a nucleoprotein. (creative-biolabs.com)
  • Among them, spike protein is the most important surface membrane protein of coronavirus. (creative-biolabs.com)
Serum7
  • Description: Quantitative sandwich ELISA for measuring Human C4 Binding Protein Alpha (C4BPA) Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. (tissue-cell-culture.com)
  • Description: A sandwich ELISA kit for detection of C4 Binding Protein Alpha from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids. (tissue-cell-culture.com)
  • Description: A sandwich ELISA for quantitative measurement of Human Alpha fetoprotein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. (rbprotein.com)
  • Therefore, we assembled a panel of human serum or plasma and polyclonal antibodies to compare the performance of serologic assays for MERS-CoV. (cdc.gov)
  • The rest might have anti-smooth muscle/anti-RyR/titin antibodies in the serum. (medscape.com)
  • In plasma cell disorders, disproportionate proliferation of one clone in the bone marrow results in a corresponding increase in the serum level of its product, the monoclonal immunoglobulin protein (M-protein). (msdmanuals.com)
  • Plasma cell disorders may be suspected because of clinical manifestations, most often bone disease, renal failure, and low blood counts, or an incidental finding of elevated serum protein or proteinuria that leads to further evaluation with serum or urine protein electrophoresis. (msdmanuals.com)
Antiserum2
  • The formation of both metabolites was inhibited by more than 90% by an antiserum directed against a pregnenolone 16 alpha-carbonitrile-inducible cytochrome P450 (P450PCN1) of rat liver. (aspetjournals.org)
  • Affinity's a2-Antiplasmin (α 2 AP also known as Alpha 2-Plasmin Inhibitor or α 2 PI) Polyclonal Antibody - HRP Conjugated is a whole IgG purified from antiserum conjugated to horseradish peroxidase. (affinitybiologicals.com)
Reagents1
  • UW-Madison researchers have developed and characterized nine murine monoclonal antibody (mAb) reagents that react uniquely with the EC1 (2x), EC2 (2x), EC5 (3x), and EC6 (2x) extracellular cadherin re. (warf.org)
Human14
  • Anti-HIF1A antibody IHC of human placenta. (lsbio.com)
  • In most human tissues, TMEM104 has a modest expression level (25-50th percentile), relative to all human proteins, according to RNA-seq data. (wikipedia.org)
  • Moreover, midazolam hydroxylase activity was immunoprecipitated from solubilized human microsomes with polyclonal antibodies against rat P450PCN1 and the closely related human isozyme P450NF. (aspetjournals.org)
  • Two of 15 human livers expressed a second immunoreactive microsomal protein of higher apparent Mr and were more active in midazolam 1'-hydroxylation. (aspetjournals.org)
  • Lee Biosolutions is a supplier of affinity purified C-Reactive Protein Polyclonal anti-Human antibody for diagnostic manufacturing and research uses. (leebio.com)
  • Procedure: Goats were immunized with Human CRP C-Reactive Protein. (leebio.com)
  • Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 21991-1-AP (PKC alpha antibody at dilution of 1:200 (under 10x lens). (ptglab.com)
  • Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 21991-1-AP (PKC alpha antibody at dilution of 1:200 (under 40x lens). (ptglab.com)
  • Description: A polyclonal antibody for detection of Met from Human, Mouse, Rat. (davincieuropeanbiobank.org)
  • We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells. (amsbio.com)
  • Immunohistochemical analysis of paraffin-embedded human colon cancer slide using 55388-1-AP (PKA C-alpha speicifc antibody at dilution of 1:50. (ptglab.com)
  • Be the first to review Human Integrin alpha 5/CD49e Biotinylated Antibody and earn rewards! (rndsystems.com)
  • Have you used Human Integrin alpha 5/CD49e Biotinylated Antibody? (rndsystems.com)
  • This antibody was prepared against a rat liver GST Yb1 and cross reacts with GST Yb1, GST Yb2 in human/rodent specimens but not with pi and alpha class GSTs. (eaglebio.com)
Peptides1
Applications3
  • This antibody is generally intended for use as a labeled primary antibody in applications such as immunoassays and immunoblotting. (affinitybiologicals.com)
  • However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution. (novusbio.com)
  • Avantor has the resources to make your Chromatography or Mass Spectrometry applications run efficiently and effectively-from the measuring apparatus needed for chromatography, or the proteins used to fulfill sample manipulation during mass spectrometry. (vwr.com)
Molecular3
  • Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. (novusbio.com)
  • The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. (rndsystems.com)
  • To decipher the molecular basis for the variation in hlgCB expression and protein production among strains, different regulation levels were analyzed in representative clinical isolates and reference strains. (bvsalud.org)
Mouse9
  • A fusion protein including aa 530-825 of the mouse HIF-1 alpha protein. (lsbio.com)
  • Monoclonal antibody raised in mouse against the N-terminus of the Cas9 nuclease (CRISPR-associated protein 9) using a recombinant protein. (diagenode.com)
  • Alternative name: Csn1 Monoclonal antibody raised in mouse against the N-terminus of the Cas9 nuclease (CRISPR-associated protein 9) using a recom. (diagenode.com)
  • Other names: m1A, 1mA, m1Ado Monoclonal antibody raised in mouse against 1-methyladenosine (m1A) conjugated to KLH. (diagenode.com)
  • Monoclonal antibody raised in mouse against 6X His epitope tag, using a KLH-conjugated synthetic peptide. (diagenode.com)
  • Neutralizes the biological activity of recombinant mouse (rm) IL-1 alpha, but will not neutralize the biological activity of rhIL-1 alpha, rhIL-1 beta, or rmIL-1 beta. (rndsystems.com)
  • Measured by its ability to neutralize IL‑1 alpha /IL‑1F1-induced proliferation in the D10.G4.1 mouse helper T cell line. (rndsystems.com)
  • 272. The Neutralization Dose (ND 50 ) is typically 0.04-0.2 µg/mL in the presence of 50 pg/mL Recombinant Mouse IL‑1 alpha /IL‑1F1. (rndsystems.com)
  • Cell Proliferation Induced by IL‑1 alpha /IL‑1F1 and Neutral-ization by Mouse IL‑1 alpha /IL‑1F1 Antibody. (rndsystems.com)
Kinase4
  • Polyclonal Antibody Branched chain a-keto acid dehydrogenase kinase (BCKD)ab. (clonagen.com)
  • The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. (novusbio.com)
  • The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. (novusbio.com)
  • Protein kinase C (PKC) can be activated by calcium and second messenger diacylglycerol. (thermofisher.cn)
Sequence1
  • Humans have a 163,255 base pair long gene coding sequence, 4703 base pair long mRNA, and 496 amino acid long protein sequence. (wikipedia.org)
Transmembrane protein3
  • Transmembrane protein 104 (TMEM104) is a protein that in humans is encoded by the TMEM104 gene. (wikipedia.org)
  • It is predicted to have between nine and eleven transmembrane domains, making it a transmembrane protein. (wikipedia.org)
  • The IL-1 receptor type I is a 80 kDa transmembrane protein with demonstrated IL-1 signaling function. (rndsystems.com)
Primary1
  • After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. (lsbio.com)
Autoimmune2
  • Test name: Myasthenia Gravis Antibody Reflex Panel/Muscle Weakness Autoimmune Panel. (medscape.com)
  • Myasthenia gravis (MG) is a relatively rare acquired, autoimmune disorder caused by an antibody-mediated blockade of neuromuscular transmission resulting in skeletal muscle weakness and rapid muscle fatigue. (medscape.com)
Amino3
  • TMEM104 variant 1 protein is 496 amino acids in length. (wikipedia.org)
  • The IB1cDNA encodes a 714 amino acid protein with a proline-rich region and a putative basic helix-loop-helix domain (bHLH). (justia.com)
  • IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. (rndsystems.com)
Receptor14
  • TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. (biossusa.com)
  • The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. (joplink.net)
  • Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. (joplink.net)
  • CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. (thermofisher.cn)
  • Two alpha subunits and two beta subunits make up the insulin receptor. (sputnic-group.ru)
  • 1 Insulin receptor functions as an enzyme that transfers phosphate groups from ATP to tyrosine residues on intracellular target proteins. (sputnic-group.ru)
  • Binding of insulin to the alpha subunits causes the beta subunits to phosphorylate themselves (autophosphorylation), thus activating the catalytic activity of the receptor. (sputnic-group.ru)
  • The activated receptor then phosphorylates a number of intracellular proteins, which in turn alters their activity, thereby generating a biological response. (sputnic-group.ru)
  • Several intracellular proteins have been identified as phosphorylation substrates for the insulin receptor, the best-studied of which is insulin receptor substrate 1 or IRS-1. (sputnic-group.ru)
  • Integrin alpha 5 beta 1 is a receptor for fibronectin and neural adhesion molecule L1. (rndsystems.com)
  • Normally, no acetylcholine receptor (AChR) antibody exists in the bloodstream. (medscape.com)
  • Anti-acetylcholine receptor antibody is found in 70-90% of patients with generalized acquired myasthenia gravis (MG). Lambert-Eaton syndrome is a close differential, as less than 13% of patients have clinical presentation similar to MG and antibodies against acetylcholine receptors in high titers. (medscape.com)
  • More than 30% of patients with MG are seronegative (ie, anti-acetylcholine receptor antibody is absent in these patients). (medscape.com)
  • These antibodies bind to the AChR on the muscle end plate and impairs binding of Ach with the receptor, which results in poor muscle strength. (medscape.com)
Biological2
  • The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. (thermofisher.cn)
  • IL-1 alpha and IL-1 beta are potent pro-inflammatory cytokines that induce a wide variety of biological activities on different cell types. (rndsystems.com)
Products1
  • IL-1 is a name that designates two proteins, IL-1 alpha and IL-1 beta, that are the products of distinct genes, but recognize the same cell surface receptors. (rndsystems.com)
Type2
  • Gentaur Protein Type: SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Uncharacterized protein 14 Design Principles: 16 polypeptides, each peptide. (proteomecommons.org)
  • M-proteins may consist of both heavy and light chains or of only one type of chain. (msdmanuals.com)
0.051
  • 0.05) expressed in the cerebellar cortex, piriform lobe, medulla, and corpus callosum of the adult yak while in the young yak brain tissues, the protein expressions were significantly found in the white matter of the cerebellum, pineal gland, corpus callosum, and cerebellar cortex. (scielo.br)
Spike1
  • We believe the answer is probable, since some of the systemic disease clinical manifestations of COVID-19 cannot be explained solely by the binding of SARS-CoV-2 spike proteins with cell membranes of tissues that exhibit angiotensin-converting enzyme 2 (ACE2). (frontiersin.org)
Gentaur2
  • EGFR Antibody is Available at Gentaur Genprice with the fastest delivery. (joplink.net)
  • CusabioEGFR Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.Online Order Payment is possible or send quotation. (joplink.net)
Gene2
  • Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. (abbkine.com)
  • We developed Proteinarium , a multi-sample protein-protein interplay (PPI) instrument , to establish clusters of sufferers with shared gene networks. (rbprotein.com)
Downstream1
  • Also acts downstream of some G-protein coupled receptors. (caslab.com)
Classification1
  • The ACR/EULAR classification requires an antinuclear antibody (ANA) titer of at least 1:80 on HEp-2 cells or an equivalent positive test at least once. (medscape.com)
Aliquot1
  • 2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year. (abbkine.com)