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  • Expression
  • Altered protamine 2 expression is uncommon in donors of known fertility, but common among men with poor fert i I izing capacity, andmay reflect other abnormalities of spermi-ogenesis. (thefreedictionary.com)
  • mechanism
  • This led to the retroviral evolutionary hypothesis for the origin of protamines through a mechanism of horizontal transmission (infection) that would account for the sporadic distribution of protamines that was observed within different organisms of distantly related phylogenetic groups (Jankowski et al. (thefreedictionary.com)
  • Cells
  • Further sensitivity to subtle changes in DNA is gained by incubation of the cells in the presence of Proteinase K, which removes protamines that otherwise impede DNA migration through the agarose. (thefreedictionary.com)
  • vitro
  • As all three serines are phosphorylated by purified CDC28-dependent H1 kinase activity in vitro, we propose a model in which the CDC28 kinase acts directly to control nuclear entry of SWI5. (ox.ac.uk)
  • stimuli
  • In this milieu, various stimuli, especially the administration of protamine, may trigger thrombosis and vasospasm. (asahq.org)
  • peak
  • Peak serum creatine kinase MB concentration occurred within 16 h of release of aortic occlusion in approximately 70% of the patients who had MI. (asahq.org)
  • yeast
  • Studies in yeast demonstrate that signaling kinases have a surprisingly active role in the nucleus, where they tether to chromatin and modulate gene expression programs. (semanticscholar.org)
  • Hours
  • If reduction in myocardial perfusion after protamine administration is persistent, myocyte necrosis may occur within hours after protamine administration. (asahq.org)