• Representative examples include the acinar cell carcinoma of the pancreas and the acinar adenocarcinoma of the prostate gland. (nih.gov)
  • NCI05) Malignant C40367 Acinic Cell Breast Carcinoma A breast adenocarcinoma characterized by the presence of serous (acinic cell) differentiation. (nih.gov)
  • Pathognomonic features of carcinoma include circumferential perineural invasion, glomerulations, mucinous fibroplasia, and glands infiltrating adipose tissue. (cap.org)
  • Dataset for the Reporting of Carcinoma of the Cervix: Recommendations From the International Collaboration on Cancer Reporting (ICCR). (patologia.ro)
  • Adenocarcinoma appearing in the rectal wall is not always rectal carcinoma. (biomedcentral.com)
  • BRCA1- and BRCA2- associated hereditary breast and ovarian cancer (HBOC) is characterized by an increased risk for female and male breast cancer, ovarian cancer (including fallopian tube and primary peritoneal cancers), and to a lesser extent other cancers such as prostate cancer, pancreatic cancer, and melanoma primarily in individuals with a BRCA2 pathogenic variant . (nih.gov)
  • Prophylactic salpingectomy followed by delayed oophorectomy or salpingo-oophorectomy for ovarian cancer prevention. (nih.gov)
  • Annual transvaginal ultrasound and serum CA-125 concentration beginning at age 35 years may be considered for ovarian cancer screening. (nih.gov)
  • However, this screening has not been effective in detecting early-stage ovarian cancer, either in high-risk or average-risk women. (nih.gov)
  • However, because the penetrance of breast, ovarian, and other cancers associated with pathogenic variants in BRCA1 and BRCA2 is less than 100%, not all individuals with a BRCA1 or BRCA2 pathogenic variant have a parent affected with cancer. (nih.gov)
  • Half of cholangiocarcinomas and ovarian mucinous carcinomas and some colorectal and pulmonary adenocarcinomas were also positive for claudin-18. (ntu.edu.tw)
  • KRAS p.Gly12Asp is a frequently occurring somatic variant in several different types of cancers, including lung, ovarian, endometrial and pancreatic (PMID: 26861459, 1875403, 24629489, 23174937). (varsome.com)
  • Screening of asymptomatic individuals for pancreatic cancer is not generally recommended. (nih.gov)
  • In addition, pancreatic tissue from mice expressing this variant show de-differentiation and activation of signaling factors that initiate pancreatic cancer (PMID: 15093544, 25623042). (varsome.com)
  • In this study, we used the immunohistochemical method to stain claudin-18 in tissue arrays containing 575 carcinomas from different anatomic sites and representative sections of 157 metastatic adenocarcinomas. (ntu.edu.tw)
  • In contrast, MUC2 is rarely detectable in aggressive pancreatic tumours, but is commonly expressed in intraductal papillary mucinous neoplasms (IPMNs), which are rare, indolent tumours, in intestinal IPMNs, and in indolent colloid carcinomas. (bmj.com)
  • These are intraductal papillary mucinous neoplasms (IPMNs), characterised by clinically detectable papillary tumours that grow within and lead to pronounced cystic dilatation of the ducts (mass forming preinvasive neoplasia). (bmj.com)
  • This case first appeared as Performance Improvement Program in Surgical Pathology (PIP) 2020, Case 29, and is metastatic prostatic adenocarcinoma found in a pre-sacral mass. (cap.org)
  • In conclusion, claudin-18 represents a sensitive and specific marker for stomach and pancreatobiliary adenocarcinoma that may be a useful diagnostic tool in routine surgical pathology. (ntu.edu.tw)
  • The surgical pathology database at the Department of Pathology (2003-2015) was searched for cases of prostate cancer with rectal wall involvement. (biomedcentral.com)
  • Horizontal tumor extent (HZTE) has limited prognostic significance in 2018 FIGO stage I endocervical adenocarcinoma (ECA): a retrospective study of 416 cases. (patologia.ro)
  • In these 9 patients, the initial symptoms in 8 patients were rectal urgency, bowel obstruction, and lower gastrointestinal bleeding, and prostate-related symptoms were not obvious. (biomedcentral.com)
  • Treatment designed to attack lung cancer cells may not work as well as treatment designed to treat a cancer of the gastrointestinal tract (i.e, the long tube running from our mouths to our rectum). (gobletcellcarcinoid.org.uk)
  • Out of 9504 patients with rectal tumors between January 2003 and January 2015, 9 patients (elderly with a mean age of 74 years) with prostate cancer involving the rectal wall were clinically misdiagnosed with rectal cancer. (biomedcentral.com)
  • This is most consistent with a diagnosis of metastatic prostatic adenocarcinoma . (cap.org)
  • In general, it is not recommended to grade metastatic prostatic adenocarcinoma. (cap.org)
  • In the metastatic cohort, 15 of 17 (88%) gastric adenocarcinomas, 18 of 23 (78%) pancreatic adenocarcinomas, and 4 of 7 (57%) cholangiocarcinomas and gallbladder adenocarcinomas were positive for claudin-18. (ntu.edu.tw)
  • In the group of primary tumors, claudin-18 was frequently expressed in gastric, pancreatic, and pulmonary mucinous adenocarcinomas. (ntu.edu.tw)
  • It is necessary to perform a differential diagnosis for prostate cancer in cases of rectal malignant tumors in elderly male patients. (biomedcentral.com)
  • Appendiceal adenocarcinomas and appendiceal typical carcinoid tumors are similar to those derived in the colon. (gobletcellcarcinoid.org.uk)
  • Tumors or cancer of the LUNG. (lookformedical.com)
  • Tumors or cancer of the human BREAST. (lookformedical.com)
  • Histologically, 2 cases showed cancer cell invasion in the mucosa, 1 showed transmural invasion from the mucosa to subserosal soft tissues, and 7 cases had submucosa and muscularis propria involvement. (biomedcentral.com)
  • In the present study, we retrospectively analyzed 9504 cases diagnosed as rectal cancer in our hospital from 2003 to 2015, and report the clinicopathological characteristics of 9 cases of prostate cancer with rectal wall invasion misdiagnosed as rectal cancer. (biomedcentral.com)
  • In sharp contrast to MUC1, MUC2 is almost never detectable in PanINs or conventional adenocarcinomas, but instead, it is commonly expressed in a rare but distinctive set of tumours that appear to form a distinct and indolent pathway of carcinogenesis. (bmj.com)
  • Where the tumour is detected can tell us what type of tumour it is - lung cancer tumours occur in lungs for example, breast cancer in breast tissue. (gobletcellcarcinoid.org.uk)
  • In a pathologic review by the Memorial Sloan Kettering Cancer Center from 1993 to 2005, a total of 63 cases were identified that fit into one of the subtypes of GCC (Tang et al. (gobletcellcarcinoid.org.uk)
  • Numerous immunohistochemical markers have been developed to determine the differentiation of tumor cells and suggest possible primary sites, but markers of gastric and pancreatic adenocarcinomas are still lacking. (ntu.edu.tw)
  • A definitive diagnosis of prostate cancer invading the rectum can be made based on the patients' history, the morphological features of the cancer, and immunohistochemical (IHC) analyses. (biomedcentral.com)
  • Once a cancer-predisposing BRCA1 or BRCA2 germline pathogenic variant has been identified in a family, testing of at-risk relatives can identify those family members who also have the familial pathogenic variant and thus need increased surveillance and specific treatments when a cancer is identified. (nih.gov)
  • These findings are highly suggestive of prostatic adenocarcinoma, but not diagnostic. (cap.org)
  • Prostate cancer involving the rectal wall is rare and may lead to diagnostic pitfalls. (biomedcentral.com)
  • The aim of the present study was to modify liver cancer cell lines in order to improve their drug-metabolizing activities towards PHH. (cancerindex.org)
  • Therefore, we screened the epigenetic status of four different liver cancer cell lines (Huh7, HLE, HepG2 and AKN-1) which were reported to have metabolizing drug activities. (cancerindex.org)
  • Clear Cell Adenocarcinoma In Situ as a Potential Precursor Lesion for Sporadic Invasive Endocervical Clear Cell Adenocarcinoma. (patologia.ro)
  • Among other actions, MUC1 may inhibit cell-cell and cell-stroma interactions and function as a signal transducer, participating in cancer progression. (bmj.com)
  • Goblet cell carcinoid was first described in 1974 as a cancer of a distinct type of cells found in our intestines - the goblet cell (Subbuswamy et al. (gobletcellcarcinoid.org.uk)
  • Data table showing topics related to specific cancers and associated disorders. (cancerindex.org)
  • Identification of the primary site of cancer is essential for the treatment of patients with cancer. (ntu.edu.tw)
  • Villoglandular Pattern in HPV-associated Endocervical Adenocarcinoma is Associated With Excellent Prognosis: A Reappraisal of 31 Cases Using IECC and Silva Pattern Classification. (patologia.ro)
  • Prostate cancer is the second most frequently diagnosed cancer and the fifth leading cause of cancer death among men worldwide [ 1 ]. (biomedcentral.com)
  • Acinar prostatic adenocarcinoma cells are cuboidal, with amphophilic to clear cytoplasm and prominent nucleoli. (cap.org)
  • Prostatic adenocarcinoma is the second most common cause of cancer-related death in men. (cap.org)
  • It is also because compared with other common cancers not too much is actually known about these cancers, partly because of their rarity. (gobletcellcarcinoid.org.uk)
  • but also very little information and support from people who have experienced this very rare cancer and we know that that isn't helping you come to terms, to understand this cancer. (gobletcellcarcinoid.org.uk)
  • The reason many doctors can be a little 'caught out' in the short term is precisely because this is a very rare cancer and many will never have seen a case. (gobletcellcarcinoid.org.uk)
  • GCC is clearly a very rare cancer occurring on average only 5 times a year at this centre. (gobletcellcarcinoid.org.uk)
  • The Sloan Kettering Hospital (which specialises in treating cancer of all types) sees 137,000 patients per year with 517,000 outpatient visits . (gobletcellcarcinoid.org.uk)
  • Whether claudin-18 can be used as a marker for identifying the primary site of cancer is still unclear. (ntu.edu.tw)
  • Prophylactic bilateral mastectomy, prophylactic oophorectomy, and chemoprevention (e.g., tamoxifen) have been used for breast cancer prevention, but have not been assessed by randomized trials in high-risk women. (nih.gov)
  • Breast cancer screening in women relies on a combination of monthly breast self-examination, annual or semiannual clinical breast examination, annual mammography, and breast MRI. (nih.gov)
  • For men, breast cancer screening includes breast self-examination education and training and annual clinical breast examination beginning at age 35. (nih.gov)