• To perform a comprehensive clinicopathological study in these subjects with complete virological, immunophenotypic, and molecular characterization of retrieved tumor tissues and peripheral blood samples for purposes of identifying prognostic and predictive biomarkers of clinical outcome (i.e. treatment response, freedom from disease progression, and overall survival) in which to begin to frame pragmatic, risk-adapted therapeutic interventions suitable for the resource constrained setting in sub-Saharan Africa. (clinicaltrials.gov)
  • These findings have not been confirmed in prospective studies, and it is not known whether the predictive power of microalbuminuria is independent of other major cardiovascular risk factors. (diabetesjournals.org)
  • To study the response to Selective Laser Trabeculoplasty (SLT) according to baseline medical treatment, angle pigmentation, age, diagnosis (open-angle glaucoma or ocular hypertension), and baseline intraocular pressure (IOP). (hindawi.com)
  • The results of this study confirm the finding that higher baseline IOP is a predictor of greater IOP response following SLT, and that pretreatment with prostaglandin analogue therapy is associated with a decreased IOP-lowering response following SLT. (hindawi.com)
  • The distinguishing feature of a prospective cohort study is that at the time that the investigators begin enrolling subjects and collecting baseline exposure information, none of the subjects have developed any of the outcomes of interest. (wikipedia.org)
  • After baseline information is collected, subjects in a prospective cohort study are then followed "longitudinally," i.e. over a period of time, usually for years, to determine if and when they become diseased and whether their exposure status changes outcomes. (wikipedia.org)
  • This prospective study evaluates the possible advantages of wrist imobilization after open carpal tunnel release comparing the results of two weeks immobilization and no immobilization. (scielo.br)
  • Leveraging the experience of our prospective research team, we have the ability to design and conduct observational, non-interventional, pragmatic and patient registry studies to collect a variety of endpoints including patient reported outcomes. (xcenda.com)
  • Oncology Reports is a monthly, peer-reviewed journal devoted to the publication of high quality original studies and reviews concerning a broad and comprehensive view of fundamental and applied research in oncology, focusing on carcinogenesis, metastasis and epidemiology. (ingentaconnect.com)
  • The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. (clinicaltrials.gov)
  • This study is part of a comprehensive assessment of the validity of FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels in Europe. (naturalnews.com)
  • Studies have shown that intense, intermittent exposures to UVR, as measured by sunburn frequency, have a higher melanoma-attributable risk than chronic UVR exposure. (aappublications.org)
  • 4 , 5 A recent meta-analysis of 51 studies found that ever reporting a sunburn during childhood almost doubled the risk for the development of cutaneous melanoma in adulthood. (aappublications.org)
  • Finally, in those studies, healthy children were compared with children with CM, but there was no assessment of whether the risk of cognitive deficits was specific to CM or occurred even with uncomplicated malaria (UM). (aappublications.org)
  • Fish oil consumption has been associated with symptom improvement in studies of women with primary dysmenorrhea and with decreased endometriosis risk in autotransplantation animal studies. (greenmedinfo.com)
  • To investigate the relation between dietary fat intake and the risk of endometriosis, we analyzed 12 years of prospective data from the Nurses' Health Study II that began in 1989. (greenmedinfo.com)
  • Our team is able to provide full-service support for prospective studies including: protocol development, site selection and management, IRB submissions and approvals, development and maintenance of online EDC tools, patient recruitment, statistical analyses and preparation of final study reports. (xcenda.com)
  • To address these issues and to obtain a robust estimate of the frequency of cognitive deficits in children with CM, we conducted a prospective study of cognitive function in the key cognitive areas of working memory, attention, and learning in Ugandan children (5-12 years of age) with CM, children with UM, and healthy community children (CC). (aappublications.org)
  • We view this study as an early step towards the development of empirical guidelines that can evolve and improve iteratively with the ultimate purpose of guiding crucial clinical decisions about whether, when, where and how to dose with a psychedelic, thus helping to mitigate risks while maximizing potential benefits in an evidence-based manner. (frontiersin.org)
  • Sign up for Insight Alerts highlighting editor-chosen studies with the greatest impact on clinical care. (aappublications.org)
  • Studies that are designed to evaluate the efficacy and safety for interventions that are used in accordance with standard practice in a real-world setting. (xcenda.com)
  • Comparative studies that are designed to evaluate the efficacy of interventions in a real-world setting. (xcenda.com)
  • As part of the Nurses' Health Study, the women reported on questionnaires mailed to them every 2 y both their consumption of nuts and whether they had undergone cholecystectomy. (foodnavigator-usa.com)
  • Women who often snack on nuts are less likely to go face surgery for gallstone disease, a major source of morbidity in developed countries, shows a new study. (foodnavigator-usa.com)
  • Many of the studies evaluating sunburning rates in adolescents have been cross-sectional designs, and are subject to limitations. (aappublications.org)
  • This study does not involve any change in treatment, but only allows the study team to follow how a patient in Kenya with lymphoma is treated. (clinicaltrials.gov)