• He has worked on developing various methods of total intravenous anesthesia (TIVA), has demonstrated the clinical use of the short acting opioid remifentanil, and defined interactions between intravenous anesthetics i.e., propofol and opioids. (wikipedia.org)
  • Thus, the authors retrospectively examined the link between propofol-based total intravenous anesthesia (TIVA) and recurrence or overall survival in patients undergoing modified radical mastectomy (MRM). (ekja.org)
  • Patients received either propofol-based TIVA (propofol group) or sevoflurane-based anesthesia (sevoflurane group). (ekja.org)
  • This retrospective study provides the possibility that propofol-based TIVA for breast cancer surgery can reduce the risk of recurrence during the initial 5 years after MRM. (ekja.org)
  • GA was induced and maintained using a propofol and remifentanil Total Intravenous Anesthesia (TIVA) technique. (heraldopenaccess.us)
  • Total intravenous anesthesia (TIVA) with propofol and remifentanil was used for anesthesia. (bvsalud.org)
  • Cerebral hypoxia was monitored using NIRS monitoring in patients who underwent controlled hypotension with total intravenous anesthesia (TIVA) or balanced general anesthesia, and the effect of anesthesia methods on postoperative cognitive function change was investigated. (clinmedjournals.org)
  • 14 ± 1.2 h), adequate sedation/analgesia was achieved by administration of progressively decreasing doses down to 187 ± 72% of propofol ID in group P, 123 ± 43% of propofol ID in group P/R and 184 ± 58% of remifentanil ID. (vin.com)
  • Patients treated with dexmedetomidine had better quality and more extended postoperative analgesia but longer postoperative anesthesia recovery and higher postoperative sedation scores when compared with remifentanil. (springeropen.com)
  • Post-operative, patient-controlled intravenous analgesia of fentanyl was provided for satisfactory analgesia until 48 h after surgery. (spandidos-publications.com)
  • Anesthesia is a medical practice that involves the administration of drugs or other techniques to induce a temporary state of unconsciousness, loss of sensation, or analgesia (relief from pain) during surgical procedures or other medical interventions. (mcqsadda.online)
  • The level of analgesia was recorded continuously using the proprietary index IOC2 (Index of consciousness 2,namely qNOX) (Angel-6000D Multi-parameter Anesthesia Monitor, Shenzhen Weihaokang Medical Technology Co., Ltd, Guangdong, China). (researchgate.net)
  • The present study showed that the intravenous midazolam and ketamine combination provides suitable sedation and analgesia to children, with low and negligible side effects. (brieflands.com)
  • General anesthesia (GA) is the state produced when a patient receives medications for amnesia, analgesia, muscle paralysis, and sedation. (medscape.com)
  • Egan is the principal creator of Safe Sedation Training (SST), a virtual preceptorship for training non-anesthesia professionals in procedural sedation. (wikipedia.org)
  • Local anesthesia with sedation offers anesthesia personnel and the surgeon great flexibility in tailoring the degree of anesthesia to the needs of the patient. (medscape.com)
  • Monitored anesthesia care (MAC) combines intravenous sedation with local anesthetic injection, infiltration including tumescent anesthesia, or nerve blocks. (medscape.com)
  • In this study, we analyzed procedural results, clinical outcomes, and follow-up angiographic findings for patients undergoing EVT for RIA under local anesthesia (LA) with conscious sedation (CS). (e-jnc.org)
  • At our institution, we performed EVT under local anesthesia (LA) with conscious sedation (CS) for all patients with RIA, regardless of the clinical severity of the subarachnoid hemorrhage (SAH). (e-jnc.org)
  • Propofol is an intravenous (IV) anesthetic medication widely used in for procedural sedation, in operating rooms, and intensive care units (ICUs). (biomedcentral.com)
  • Narcolepsy, Anesthesia, and Sedation: A Survey of the Perioperative Experience of Patients With Narcolepsy. (stopbang.ca)
  • After isoflurane discontinuation, the animals received either propofol (group P, n=4) or propofol plus remifentanil (group P/R, n=4) by continuous intravenous infusion for a maximum period of 38 hours. (vin.com)
  • Anesthesia was maintained with 50 % air in O 2 , 0.5 MAC sevoflurane and remifentanil infusion 0.25 µg kg -1 min -1 . (ispub.com)
  • The current study was conducted to evaluate the clinical efficacy of dexmedetomidine infusion compared to that of remifentanil for controlled hypotension in patients undergoing shoulder arthroscopy. (springeropen.com)
  • In group D, IV dexmedetomidine l μg/kg was infused over 10 min before anesthesia induction, followed by a continuous infusion of 0.3-0.6 μg/kg/h during the operation. (springeropen.com)
  • Propofol infusion rates were varied to modify plasma concentrations. (asahq.org)
  • Patient perception of pain was scored with the verbal rating scale (VRS) every 5 s after the start of the propofol infusion, and the evaluation was stopped once the patient became unresponsive. (biomedcentral.com)
  • The burning pain from propofol infusion travels along the blood vessels, causing discomfort and anxiety in patients, and may even result in a traumatic anesthesia experience, making propofol infusion-related pain the major problem encountered in clinical anesthesia practice [ 3 ]. (biomedcentral.com)
  • Spinal Anesthesia: In spinal anesthesia, a local anesthetic is injected into the cerebrospinal fluid surrounding the spinal cord, resulting in a temporary loss of sensation and motor function below the level of injection. (mcqsadda.online)
  • It provides pain relief and loss of sensation in a larger region of the body than spinal anesthesia and is frequently used during labor and childbirth or for surgeries involving the lower abdomen and legs. (mcqsadda.online)
  • Hemodynamic effects of lateral tilt before and after spinal anesthesia during cesarean delivery: an observational study. (medscape.com)
  • Sedative and Analgesic Effects of Intravenous Midazolam and Ketamine Combin. (brieflands.com)
  • Tabatabaei S M N , Miri-Aliabad G, Borjian Boroojeny S, Arab A. Sedative and Analgesic Effects of Intravenous Midazolam and Ketamine Combination in Bone Marrow Aspiration and Biopsy of Childhood Cancer. (brieflands.com)
  • This study aimed to evaluate the effectiveness of intravenous midazolam and ketamine combination in bone marrow aspiration and biopsy in children with cancer. (brieflands.com)
  • An adult male patient in his fifth decade of life presented for elective surgical resection of a long standing neck mass, and underwent general anesthesia with tracheal intubation facilitated by mivacurium neuromuscular blockade. (heraldopenaccess.us)
  • Dosing study of remifentanil and propofol for tracheal intubation without the use of muscle relaxants. (druglib.com)
  • Sore throat and hoarseness frequently occur following general anesthesia with tracheal intubation and are effectively reduced when dexamethasone is used prophylactically. (anesth-pain-med.org)
  • The risk factors for sore throat and hoarseness include sex (female), age (young), pre-existing lung disease, prolonged duration of anesthesia, intubation without neuromuscular blockade, use of double-lumen tubes, and high tracheal tube cuff pressures [ 1 ]. (anesth-pain-med.org)
  • Intravenous dexmedetomidine pre-medication reduces the required minimum alveolar concentration of sevoflurane for smooth tracheal extubation in anesthetized children: a randomized clinical trial. (medscape.com)
  • We analyzed prognostic factors of breast cancer and perioperative factors and compared recurrence-free survival and overall survival between propofol and sevoflurane groups. (ekja.org)
  • 325 cases were suitable for analysis (173 cases of propofol group, and 152 cases of sevoflurane group). (ekja.org)
  • The use of opioids during the perioperative period was greater in propofol group than in sevoflurane group. (ekja.org)
  • Perioperative incidence of airway obstructive and hypoxemic events in patients with confirmed or suspected sleep apnea - a prospective, randomized pilot study comparing propofol/remifentanil and sevoflurane/remifentanil anesthesia. (medscape.com)
  • Comparison of a loading dose of dexmedetomidine combined with propofol or sevoflurane for hemodynamic changes during anesthesia maintenance: a prospective, randomized, double-blind, controlled clinical trial. (medscape.com)
  • This project was designed to compare the dose requirements and the development of tolerance on the sedative/analgesic effect of propofol versus propofol plus remifentanil administered in rabbits under prolonged mechanical ventilation (PMV). (vin.com)
  • The effect of propofol/remifentanil rapid-induction technique without muscle relaxants on intraocular pressure. (druglib.com)
  • Epidural Anesthesia: Epidural anesthesia involves injecting a local anesthetic into the epidural space, which is the area outside the spinal cord covering. (mcqsadda.online)
  • An adult male patient in his fifth decade of life and of American Society of Anesthesiologists' Physical Status 1 had previously undergone General Anesthesia (GA) for excision of a submandibular gland uneventfully. (heraldopenaccess.us)
  • As we were under the impression that the use of intraoperative nerve stimulation and monitoring by our surgical colleagues was functioning prior to emergence from general anesthesia, we initially excluded the possibility of postoperative residual neuromuscular blockade. (heraldopenaccess.us)
  • Therefore, this study aimed to evaluate the efficacy of preconditioning with nasal splint and mouth-breathing training on prevention of ED after general anesthesia. (bvsalud.org)
  • Forty patients undergoing elective arthroscopic shoulder surgery under general anesthesia were enrolled in the current study. (springeropen.com)
  • Both remifentanil and dexmedetomidine can induce adequate levels of hypotensive anesthesia and satisfactory surgical field visibility in patients undergoing shoulder arthroscopy under general anesthesia. (springeropen.com)
  • We aimed to assess the maternal and neonatal outcomes when the LMA Supreme was used for cesarean section under general anesthesia. (frontiersin.org)
  • We included all patients who underwent general anesthesia for cesarean section between January 2010 and December 2019. (frontiersin.org)
  • The LMA Supreme was not associated with higher adverse maternal and neonatal outcomes when compared to an endotracheal tube for cesarean section under general anesthesia. (frontiersin.org)
  • Although previous studies have reported the successful use of the LMA in cesarean section, the role of LMA in obstetric general anesthesia is, to date, still highly debatable ( 12 - 17 ). (frontiersin.org)
  • Following ethical approval by the Ethics Committee of Peking University First Hospital (No. 2021-226, date of approval: 23 June 2021, Chairman: Professor Yanyan Yu), a retrospective cohort study was carried out on patients who received general anesthesia for cesarean section over a period of 10 years (January 2010 to December 2019). (frontiersin.org)
  • 13.- Salomäki TE, Laurila PA, Ville J. Successful resuscitation after cardiovascular collapse following accidental intravenous infusión of levobupivacaine during general anesthesia. (revistaanestesiar.org)
  • 2] Liu SS, Strodtbeck WM, Richman JM, Wu CL: A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials. (edu.pl)
  • To determine the effect of parental smoking (PS) exposure on the incidence of respiratory complications in children who received general anesthesia. (bakirkoymedj.org)
  • A total of 98 children aged 0-16 years who had an American Society of Anesthesiologists Physical Status score of 1-2 and underwent general anesthesia were included in the study. (bakirkoymedj.org)
  • PS exposure increased the incidence of respiratory complications in children undergoing general anesthesia, and the frequency of complications increased as the distance of exposure decreased. (bakirkoymedj.org)
  • All patients with an American Society of Anesthesiologists Physical Status score of 1-2 who underwent general anesthesia were included in the study. (bakirkoymedj.org)
  • One hundred and twenty-eight gastric cancer patients scheduled to undergo radical gastrectomy under general anesthesia were enrolled in the study. (spandidos-publications.com)
  • General anesthesia is used for major surgeries and procedures that require the patient to be completely still and have no recollection of the event. (mcqsadda.online)
  • Patients given monitored anesthesia rather than general anesthesia experience fewer incidences of nausea and vomiting and typically can be discharged home safely and quickly. (medscape.com)
  • At most centers, general anesthesia (GA) has been preferred for endovascular treatment (EVT) of ruptured intracranial aneurysms (RIAs). (e-jnc.org)
  • At most centers, coil embolization for ruptured intracranial aneurysm (RIA) is performed under general anesthesia (GA), which provides optimal conditions for the procedure [ 2 ]. (e-jnc.org)
  • Methods: The study was approved by the local ethics committee, including data from 60 patients scheduled for ambulatory surgery undergoing general anaesthesia with propofol and remifentanil, using TCI. (researchgate.net)
  • Conclusion: The qCON was able to reliably detect LOC during general anaesthesia with propofol and remifentanil. (researchgate.net)
  • The majority of patients may experience atelectasis under general anesthesia, and the Trendelenburg position and pneumoperitoneum can aggravate atelectasis during laparoscopic surgery, which promotes postoperative pulmonary complications. (biomedcentral.com)
  • During general anesthesia, ultrasound-guided recruitment manoeuvres can reduce perioperative aeration loss and improve oxygenation. (biomedcentral.com)
  • Expired alveolar gas and mixed venous and arterial blood were simultaneously sampled during continuous application of propofol for general anesthesia to three goats and three pigs. (asahq.org)
  • Sore throat and hoarseness are common complications of general anesthesia. (anesth-pain-med.org)
  • Intravenous dexamethasone is prophylactically used to prevent the sore throat and hoarseness that occur after general anesthesia owing to airway intubation [ 1 , 4 - 7 ]. (anesth-pain-med.org)
  • General anesthesia uses intravenous and inhaled agents to allow adequate surgical access to the operative site. (medscape.com)
  • Mortality attributable to general anesthesia is said to occur at rates of less than 1:100,000. (medscape.com)
  • Unusual elevation in Entropy but not in PSI during general anesthesia: a case report. (medscape.com)
  • Eight male, clinically healthy New Zealand White rabbits were intubated under xylazine-ketamine-isoflurane anesthesia. (vin.com)
  • Ketamine can attenuate pain associated with IV propofol injection through local and central analgesic effects. (biomedcentral.com)
  • Our differential diagnoses at this time, included perioperative stroke, and inadvertent intrathecal local anesthesia administration. (heraldopenaccess.us)
  • The Amazon Echo brings us Alexa, an AI-powered personal assistant who follows verbal commands in our homes.Artificial intelligence in medicine (AIM) will grow in importance in the decades to come and will change anesthesia practice, surgical practice, perioperative medicine in clinics, and the interpretation of imaging. (theanesthesiaconsultant.com)
  • There was a surgical requirement for intraoperative nerve monitoring within the operative area, thus neuromuscular paralysis was achieved with Intravenous (IV) injection of 15mg of Mivacurium (0.2mg per kg). (heraldopenaccess.us)
  • The main objective is the comparison of intubation conditions after anesthetic induction bolus of propofol-sufentanil when compared to injection of propofol-remifentanil in patients undergoing surgery for tooth extraction. (druglib.com)
  • Accidental injection of intravenous bupivacaine. (revistaanestesiar.org)
  • Successful resuscitation after inadvertent intravenous injection of bupivacaine in an adolescent. (revistaanestesiar.org)
  • The purpose of our study is to determine the half effective dose (ED 50 ), 95% effective dose (ED 95 ), and 99% effective dose (ED 99 ) of esketamine for attenuating propofol injection pain using Dixon's up-and-down method to provide a reference for optimal dose selection for surgeries and procedures. (biomedcentral.com)
  • Thirty gynecological patients undergoing hysteroscopic surgery were enrolled in a sequential method to determine the effective dose of esticketamine for analgesic propofol injection in order of operation. (biomedcentral.com)
  • We recommended a dose of 0.2 mg/kg IV esketamine before induction of anesthesia to reduce the pain of propofol injection. (biomedcentral.com)
  • Previous research showed the use of supraglottic airways in obstetric anesthesia. (frontiersin.org)
  • Research on obstetric anesthesia should focus on reducing anesthesia-related morbidity and ensuring the safety of both the mother and neonate. (frontiersin.org)
  • Egan's research interests revolve around clinical pharmacology investigative methods applied to the development and understanding of novel intravenous anesthetics and opioids, optimal anesthetic drug administration regimens, and anesthetic drug interactions. (wikipedia.org)
  • Patients were randomly distributed into one of two equal groups: dexmedetomidine group (D group) and remifentanil group (R group) according to the agent used for controlled hypotension. (springeropen.com)
  • Patients using ACEIs or ARBs have been reported to be prone to hypotension during the administration of anesthesia. (medscape.com)
  • [ 2 ] The choice and route of anesthesia administration is paramount to the patient's overall surgical experience. (medscape.com)
  • Anesthesia providers are responsible for assessing all factors that influence a patient's medical condition and selecting the optimal anesthetic technique accordingly. (medscape.com)
  • Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers. (wikipedia.org)
  • Remifentanil pharmacokinetics in obese versus lean patients. (wikipedia.org)
  • Comparative study of ultrasound-guided paravertebral block versus intravenous tramadol for postoperative pain control in percutaneous nephrolithotomy. (medscape.com)
  • The patient was premedicated with ranitidine 50 mg I.V. Anesthesia was induced with propofol 2 mg kg -1 and remifentanil 1 µg kg -1 I.V. bolus dose. (ispub.com)
  • In group R, 1 μg/kg remifentanil IV bolus was administered before induction of anesthesia and continued 0.25-0.50 μg/kg/min during the operation. (springeropen.com)
  • The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers. (wikipedia.org)
  • Remifentanil pharmacokinetics and pharmacodynamics. (wikipedia.org)
  • Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil: I. Model development. (wikipedia.org)
  • Comparison of Intubation Conditions After Induction With Propofol Associated With a Dose of Remifentanil or Sufentanil in Surgical Tooth Extraction. (druglib.com)
  • Bouvet L, Stoian A, Rimmelé T, Allaouchiche B, Chassard D, Boselli E. Optimal remifentanil dosage for providing excellent intubating conditions when co-administered with a single standard dose of propofol. (druglib.com)
  • During induction, the target dose of esketamine was first given via venous access in the left hand of the patient, and 30 s later, a fixed dose of 2 mg/kg (1 ml/s) of propofol was given. (biomedcentral.com)
  • In Reply: Optimal Propofol Induction Dose in Morbidly Obese Patients: Bispectral Index Guidance is Not the Answer. (stopbang.ca)
  • Optimal Propofol Induction Dose in Morbidly Obese Patients: A Randomized Controlled Trial Comparing the Bispectral Index and Lean Body Weight Scalar. (stopbang.ca)
  • We sought to evaluate the costs and benefits of preoperative administration of 1 g of intravenous TXA, without maintenance, in DLS patients undergoing long-segment spinal fusion surgery. (medscimonit.com)
  • Anesthesiologists should know the comprehensive preoperative assessment and underlying pathophysiologic condition, determine an anesthesia plan for patients with HPS, meticulously account for HPS-related hypoxia and PVR conditions, and follow up closely perioperatively for successful outcomes. (transpopmed.org)
  • Intubation without myorelaxant with propofol and sufentanil is classic but less efficient than induction with curare on achieving perfect intubation conditions. (druglib.com)
  • 1.Which of the following is a commonly used intravenous induction agent? (mcqsadda.online)
  • Bradycardia occurred in only one patient during anesthesia induction, while hemodynamics was stable in the rest of the patients without obvious adverse reactions. (biomedcentral.com)
  • Anesthesia enables a patient to tolerate surgical procedures that would otherwise inflict unbearable pain, potentiate extreme physiologic exacerbations, and result in unpleasant memories. (medscape.com)
  • Comparison of etomidate-remifentanil and. (deu.edu.tr)
  • Objective The aim of the study was to compare haemodynamic responses, recovery and discharge times, and physician satisfaction of etomidate-remifentanil and propofol-remifentanil combinations in patients undergoing elective colonoscopy. (deu.edu.tr)
  • A major representative of the latter group is the intravenous narcotic propofol (2,6-diisopropyl-phenol), which is currently used in a wide range of anesthetic procedures. (asahq.org)
  • In conclusion, both propofol and remifentanil lead to tolerance with regard to their sedative and analgesic effect in PMV rabbits within the first few hours. (vin.com)
  • In a randomized, prospective, parallel, controlled trial, 216 patients undergoing elective thoracic pulmonary resection under one-lung ventilation with propofol-remifentanil anesthesia were randomized 1:1 to receive either limb RIPC or conventional lung resection (control). (silverchair.com)
  • Correction to: Interventions to Reduce Medication Errors in Anesthesia: A Systematic Review. (stopbang.ca)
  • Local anesthesia encompasses infiltration of the operative site, tumescent techniques, and nerve blocks . (medscape.com)
  • We think that, the desflurane group be preferred as a priority with less remifentanil expenditure, lower blood pressure values, higher rSO 2 values, no 20% decrease in rSO 2 values, faster extubation, and statistically significant early recovery. (clinmedjournals.org)
  • The patients were randomly divided into two groups, Group D (desflurane) and Group P (propofol). (clinmedjournals.org)
  • Although the concurrent administration of propofol with remifentanil does not affect the ID of propofol, it reduces the rate and delays the occurrence of its tolerance. (vin.com)
  • In vitro and in vivo studies suggest that propofol independently reduces migration of cancer cells and metastasis. (ekja.org)
  • Concurrent and longitudinal follow-up was then conducted upon admission to the post-anesthesia care unit (PACU) for the first hour. (revcolanest.com.co)
  • BACKGROUND: Emergence delirium (ED) is generally occurred after anesthesia associated with increased risks of long-term adverse outcomes. (bvsalud.org)
  • The purpose of using MCQs in anesthesia education is to ensure that individuals have a solid foundation of knowledge necessary for safe and effective anesthesia practice. (mcqsadda.online)
  • It is essential to consider patient safety, evidence-based practice, and the latest guidelines when making decisions in anesthesia. (mcqsadda.online)
  • Local anesthesia is administered by injecting or topically applying an anesthetic drug directly to a specific area of the body. (mcqsadda.online)