• 1957 - March 1999) was a Chinese virologist and cancer researcher, who with fellow researcher Ian Frazer, invented Gardasil and Cervarix, the vaccines for stimulating human immunological resistance to the cervical cancer-inducing human papilloma virus. (wikipedia.org)
  • In 2008, Zhou's contribution to his efforts in research, including his work with the Gardasil vaccine, were formally recognised with a commemorative service attended by over 300 people, and included a written tribute from the Australian Prime Minister of the time, Kevin Rudd in Brisbane, Australia. (wikipedia.org)
  • The HPV 9-valent (Gardasil 9) is the only HPV vaccine available in the United States. (medscape.com)
  • The HPV 2-valent vaccine (Cervarix), which covered types 16 and 18, and the HPV 4-valent vaccine (Gardasil), which covered types 6, 11, 16, and 18, were discontinued in the United States in October 2016. (medscape.com)
  • A nonavalent vaccine (Gardasil 9) is currently in production which will provide an even greater degree of protection (against 9 HPV types instead of 4: HPV 6/11/16/18/31/33/45/52/58). (nursinginpractice.com)
  • In June 2006, the US Food and Drug Administration approved Gardasil, a quadrivalent HPV 6, 11, 16 and 18 recombinant vaccine. (iospress.com)
  • Indicated for young girls and women aged 9 to 26, Gardasil is the first vaccine approved to prevent transmission of HPV types 16 and 18. (iospress.com)
  • Novaplex showed high type-specific concordance with the reference method for HPV16/18, 9 types targeted by the Gardasil 9 vaccine, 14 high-risk types, and 21 types covered by comparison assays. (cdc.gov)
  • Our model considers the impact of vaccination on squamous cell carcinomas, adenocarcinomas, cervical cancers due to high risk human papillomavirus types not in the vaccine, non-cervical cancers, and anogenital warts. (bmj.com)
  • The identification of high-risk human papillomavirus (hrHPV) types (the cause of cervical cancer) offers the prospect of improving cervical screening programmes through the introduction of hrHPV-based screening tests. (samj.org.za)
  • Most human papillomavirus infection is harmless and clears spontaneously but persistent infection with high-risk human papillomavirus (especially type 16) can cause cancer of the cervix, vulva, vagina, anus, penis, and oropharynx. (elsevierpure.com)
  • Cervical cancer (CC) kills a 250,000 people annually, frequently affecting young women, and requires persistent infection with high-risk Human Papillomavirus (hrHPV) for its development. (prescriptec.org)
  • Studies have shown that infection with high-risk human papillomavirus (HPV) can lead to cervical cancer. (who.int)
  • subgroups of subjects with no evidence of previous exposure to relevant vaccine HPV types were evaluated separately for vaccine efficacy. (wikipedia.org)
  • Why is vaccine efficacy modest in the entire cohort? (wikipedia.org)
  • One factor is the apparent lack of efficacy among subjects with evidence of previous exposure to HPV types included in the vaccine. (wikipedia.org)
  • Background: A randomised double-blind placebo-controlled phase II study was done to assess the efficacy of a prophylactic quadrivalent vaccine targeting the human papillomavirus (HPV) types associated with 70% of cervical cancers (types 16 and 18) and with 90% of genital warts (types 6 and 11). (johnshopkins.edu)
  • A bivalent vaccine with the same efficacy against human papillomavirus types 16 and 18 costing £13-£21 less per dose (depending on the duration of vaccine protection) may be as cost effective as the quadrivalent vaccine although less effective as it does not prevent anogenital warts. (bmj.com)
  • For these recommendations, ACIP considered information on vaccine efficacy (including data available since October 2009, on prevention of grade 2 or 3 anal intraepithelial neoplasia [AIN2/3], a precursor of anal cancer), vaccine safety, estimates of disease and cancer resulting from HPV, cost-effectiveness, and programmatic considerations. (cdc.gov)
  • Efficacy for prevention of HPV 6-, 11-, 16- and 18-related genital warts among males who received at least 1 vaccine dose, regardless of baseline infection or serology (intent to treat population), was 68.1% (CI = 48.8%-80.7%) ( 4 ). (cdc.gov)
  • The dose of the vaccine varies significantly from study to study, making it very difficult to compare immune responses and vaccine efficacy. (mdpi.com)
  • High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up. (vakciny.net)
  • We report data for the longest efficacy evaluation to date of a prophylactic HPV vaccine. (vakciny.net)
  • Adolescents, parents, and carers showed a low proportion of correctness about the safety and efficacy of the vaccine. (bvsalud.org)
  • ABSTRACT Data about the public's awareness and acceptability of the human papilloma virus (HPV) vaccine are lacking in the Eastern Mediterranean Region. (who.int)
  • HPV vaccines protect against two to seven high-risk strains of this family of viruses and may prevent up to 90% of cervical cancers. (wikipedia.org)
  • The vaccine completely protects unexposed women against four HPV strains responsible for 70% of cervical cancers, which kill about 250,000 women annually. (wikipedia.org)
  • In particular, human papillomavirus types 16 and 18 are associated with 70% of cervical cancers, 3 whereas 90% of anogenital warts are linked to human papillomavirus types 6 and 11. (bmj.com)
  • The introduction of HPV vaccines has also drawn more attention to the fact that HPV is associated not only with cervical cancer and genital warts but also with other tumors, such as head neck and anogenital cancers ( 3 ). (cdc.gov)
  • With HPV vaccine, we have a powerful tool to prevent most of these cancers from ever developing. (cdc.gov)
  • Background Human papillomavirus (HPV) DNA is present in the majority of squamous cell cancers of the anus. (researchgate.net)
  • Prophylactic human papillomavirus (HPV) vaccines are recommended for prevention of HPV-associated cancers. (cdc.gov)
  • Human papillomaviruses (HPVs) cause virtually all cervical cancers, the second leading cause of death by cancer among women, as well as other anogenital cancers and a subset of head and neck cancers. (virosin.org)
  • In this review, we summarize some recent findings on HPV-associated carcinogenesis, such as miRNAs in HPV-associated cancers, implication of stem cells in the biology and therapy of HPV-positive cancers, HPV vaccines, targeted therapy of cervical cancer, and drug treatment for HPV-induced intraepithelial neoplasias. (virosin.org)
  • Over 200 human papillomavirus (HPV) types, which are members of five genera ( α, β, γ, μ, v ) [ 1 , 2 ], are responsible for approximately 5% of all human cancers and substantial precancerous and benign lesions [ 3 , 4 ]. (oncotarget.com)
  • The preventive effect of HPV vaccines against anogenital and oropharyngeal cancers has been proven in both clinical trials and real-world data. (mdpi.com)
  • The two currently licensed human papillomavirus (HPV) vaccines are highly efficacious in preventing cervical pre-cancers related to HPV 6, 11, 16 and 18. (who.int)
  • We are pursuing applications of this technology for both therapeutic and preventive vaccines. (globenewswire.com)
  • Since the introduction of human papillomavirus (HPV) vaccines, both primary and secondary preventive (i.e., screening) measures have been available to prevent cervical cancer. (biomedcentral.com)
  • As for all preventive public health interventions, high coverage of the target population with HPV vaccines pre-exposure is essential to achieve maximum reduction of cases: therefore, in order to obtain the maximum and most equitable coverage and future benefit, programs targeting adolescents before exposure to HPV should be preferred and population-based. (unifi.it)
  • Preventive screening programmes and vaccination against human papillomavirus (HPV) result in reduced cancer incidence and mortality. (prescriptec.org)
  • In the four years after the vaccine was recommended in 2006, the amount of HPV infections among teen girls in the U.S. dropped by more than half. (cdc.gov)
  • The medications used to treat human papillomavirus (HPV) infections are primarily designed to ablate the lesion by virtue of their corrosive properties. (medscape.com)
  • they are only useful for cancer known to be caused by infections, such as the HPV (human papillomavirus) vaccine. (canceraustralia.gov.au)
  • The World Health Organization (WHO) reports that licensed vaccines are currently available for twenty-five different preventable infections . (webot.org)
  • Despite the optimism that has accompanied the introduction of prophylactic vaccines to prevent some HPV infections, the relatively modest uptake of the vaccine, especially in the developing world, and the very high fraction of men and women who are already infected, means that HPV-associated disease will remain as a significant public health problem for decades. (virosin.org)
  • Therefore, the development of second-generation vaccines that are expected to be cheaper, easier to deliver and/or to provide T-cell response against pre-existing HPV infections is highly desirable. (iarc.fr)
  • Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. (medscape.com)
  • Bivalent or quadrivalent vaccines were administered indiscriminately. (bvsalud.org)
  • 5 Two prophylactic vaccines against human papillomavirus (a bivalent vaccine against types 16 and 18 and a quadrivalent vaccine that also includes types 6 and 11) have been shown to be efficacious in up to five years of follow-up against types 16 and 18 cervical infection and associated disease as well as against anogenital warts. (bmj.com)
  • The same cost effectiveness model was later used to inform the adjudication process between the two vaccines, which led to a decision to use the bivalent vaccine in the UK immunisation programme. (bmj.com)
  • One of these is Cervarix TM , an AS04-adjuvanted bivalent vaccine against HPV types 16 and 18 produced by GlaxoSmithKline. (biomedcentral.com)
  • It is a bivalent vaccine containing two recombinant, replication-deficient lymphocytic choriomeningitis virus (rLCMV) vectors, one expressing the pp65 protein and one expressing the gB protein of human cytomegalovirus (HCMV). (pharmaceutical-technology.com)
  • The main risk factor for cervical cancer is the presence of human papillomavirus (HPV) infection. (vitalitymagazine.com)
  • Worldwide there is a strong relation between the presence of human papillomavirus (HPV) and the development of cervical cancer. (nih.gov)
  • A new study by researchers from the International Agency for Research on Cancer (IARC), in collaboration with the Ministry of Health of Rwanda and partner institutions, has shown that vaccination against human papillomavirus (HPV) has more than halved the prevalence of high-risk HPV types in Rwanda in less than 8 years. (who.int)
  • Effectiveness of Prophylactic Human Papillomavirus Vaccine in the Prevention of Recurrence in Women Conized for HSIL/CIN 2-3: The VENUS Study. (bvsalud.org)
  • In conclusion, a prophylactic quadrivalent HPV vaccine was effective through 5 years for prevention of persistent infection and disease caused by HPV 6/11/16/18. (vakciny.net)
  • This guideline on human papillomavirus (HPV) in individuals with HIV was developed by the New York State Department of Health AIDS Institute (NYSDOH AI) to inform primary care providers and other practitioners in New York State about HPV prevention, screening methods, diagnosis and presentation, and treatment in adults with HIV. (hivguidelines.org)
  • Primary prevention by prophylactic vaccination against the major cause of cervical cancer, the carcinogenic human papillomavirus (HPV) types 16 and 18, is now available worldwide. (sanevax.org)
  • Human papillomavirus detection is very important for the evaluation of prevention strategies in cervical cancer. (biomedcentral.com)
  • These results suggest that behavioral health factors may be associated with vaccine acceptability and further our understanding of how behavioral patterns may contribute to the uptake of new cancer prevention strategies. (aacrjournals.org)
  • In 2006, the U.S. Food and Drug Administration (FDA) approved the first HPV vaccine for administration to females 9 to 26 years of age for the prevention of cervical cancer ( 5, 6 ). (aacrjournals.org)
  • Two effective prophylactic vaccines composed of human papillomavirus type 16 and 18, and human papillomavirus type 16, 18, 6, and 11 virus-like particles have been introduced in many developed countries as a primary prevention strategy. (elsevierpure.com)
  • Human papillomavirus testing is clinically valuable for secondary prevention in triaging low-grade cytology and as a test of cure after treatment. (elsevierpure.com)
  • We estimated the prevalence of oral human papillomavirus (HPV) and assessed risk factors among young heterosexual men participating in the HPV Infection and Transmission among Couples through Heterosexual Activity (HITCH) study. (aacrjournals.org)
  • This cross-sectional study describes the age-specific prevalence of human papillomavirus (HPV) infection and cytological abnormalities among this urban and peri-urban population. (samj.org.za)
  • Before implementing a large-scale HPV vaccine campaign in Viet Nam, information about the prevalence of infection with the HPV vaccine types is required. (who.int)
  • While it is relevant to implement an HPV vaccine campaign in Viet Nam due to the high prevalence of infection with HPV 16 and/or 18, it is important to note that one can be infected with multiple types of HPV. (who.int)
  • Before implementing a large-scale HPV vaccine campaign in the south of Viet Nam, updated data on the prevalence and distribution of the vaccine types of HPV among women is required. (who.int)
  • Human papillomavirus (HPV) infection is now recognized as the main cause of cervical cancer, the role of coexisting factors is better understood, a new cytology reporting terminology has improved diagnosis and management of precursor lesions, and specific treatment protocols have increased survival among patients with early or advanced disease. (cmaj.ca)
  • The discovery that the Human PapillomaVirus (HPV) is the necessary cause of cervical cancer has led to the development of prophylactic vaccines. (unifi.it)
  • Although immunization with the human papillomavirus vaccine is recommended for all boys and girls, vaccination rates remain low. (aafp.org)
  • Immunization is coded 3E0134Z Introduction of Serum, Toxoid and Vaccine into Subcutaneous Tissue, Percutaneous Approach. (fortherecordmag.com)
  • Immunization administration for vaccines and toxoids is located in the Medicine section of the CPT coding manual. (fortherecordmag.com)
  • In Brazil, since 2014, the vaccine has been adopted in the National Immunization Program (PNI), targeting female adolescents from 9 to 13 years old 5 . (bvsalud.org)
  • The purpose of this study was to assess the cost-effectiveness of adding vaccination with the AS04-adjuvanted human papillomavirus 16/18 vaccine (Cervarix TM ) at age 12 to the current national cervical screening program. (biomedcentral.com)
  • Therapeutic vaccines for genital HPV infection are also possible, but have not yet been demonstrated as feasible in practice because the choice of vaccine antigens is difficult, the method of their optimal delivery is uncertain, and the nature of the relevant antiviral immunity is unknown. (nih.gov)
  • iBioModulator has been used as a fusion to express peptide or protein domain antigens in a number of other successful vaccine candidates, including those for anthrax, plague, sleeping sickness and influenza. (globenewswire.com)
  • The iBioModulator also has been used by scientists at the Fraunhofer USA Center for Molecular Biotechnology to improve the solubility and stability not only of recombinant vaccine antigens, but other proteins as well. (globenewswire.com)
  • 2 , 5 Administration of acetaminophen at the time of vaccination or shortly afterward may alleviate some adverse effects, but there may be a decreased antibody response to some vaccine antigens in children who receive antipyretics. (aafp.org)
  • A three component mix of thioredoxin-L2 antigens elicits broadly neutralizing responses against oncogenic human papillomaviruses. (unipr.it)
  • HPV vaccine on HPV infection and disease in the US pop- incidence and deaths have substantially decreased in coun- ulation? (cdc.gov)
  • The primary endpoint was the combined incidence of infection with HPV 6, 11, 16, or 18, or cervical or external genital disease (ie, persistent HPV infection, HPV detection at the last recorded visit, cervical intraepithelial neoplasia, cervical cancer, or external genital lesions caused by the HPV types in the vaccine). (johnshopkins.edu)
  • Human papillomaviruses are responsible for nearly 3000 cases of cervical cancer 1 and more than 100 000 diagnosed cases of anogenital warts 2 in the United Kingdom every year, despite a decrease in the incidence of cervical cancer as a result of regular cytological screening. (bmj.com)
  • 7 8 Both vaccines have the potential to bring a decrease in the incidence of human papillomavirus related disease and are being considered for routine immunisation in many countries. (bmj.com)
  • At 5 years post enrollment, the combined incidence of HPV 6/11/16/18-related persistent infection or disease was reduced in vaccine-recipients by 96% (two cases vaccine versus 46 placebo). (vakciny.net)
  • Despite the availability of a prophylactic vaccine, the incidence of HPV-driven oropharyngeal cancer continues to increase ( 1 ). (aacrjournals.org)
  • Family physicians should gather accurate information about the harms and benefits of vaccines to advocate for vaccination and decrease the incidence of vaccine-preventable diseases. (aafp.org)
  • 3 The fourth dose of the diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine is associated with an increased incidence of fever and injection site reactions compared with the first dose (one in four children). (aafp.org)
  • The development of a prophylactic vaccine to prevent infection with oncogenic subtypes of human papillomavirus (HPV) is an important step in reducing cervical cancer incidence and mortality. (aacrjournals.org)
  • This prophylactic vaccination is expected to reduce the incidence of HPV-related genital diseases. (iarc.fr)
  • The standardized incidence of cervical the HPV vaccine ( 12 , 13 ). (who.int)
  • Clinical and epidemiological correlates of antibody response to human papillomaviruses (HPVs) as. (sagepub.com)
  • This ninetieth volume of the IARC Monographs on the Evaluation of Carcinogenic Risks to Humans considers human papillomaviruses (HPVs), which were evaluated by a previous Working Group (IARC, 1995). (iarc.fr)
  • Current research has focused on the determinants of infection with oncogenic HPV types, the assessment of prophylactic and therapeutic vaccines and the development of screening strategies incorporating HPV testing and other methods as adjunct to cytology. (cmaj.ca)
  • 6 7 In addition, the results from clinical trials suggest that both vaccines may offer partial protection against oncogenic human papillomavirus types not in the vaccine. (bmj.com)
  • Recent data have shown that the human papillomavirus (HPV) vaccine could impact on a decrease in high-grade cervical intraepithelial lesions (HSIL) in women who have undergone surgical treatment . (bvsalud.org)
  • Snow leopards ( Uncia uncia ) develop papillomavirus (PV) lesions in the mouth and on the skin. (vin.com)
  • 1. Human papillomavirus (HPV) genotyping, HPV type-specific E6/E7 transcript detection, and hTERT transcript detection could improve the specificity of predicting subsequent development of squamous intraepithelial lesions, compared with cocktail HPV DNA detection alone. (hkmj.org)
  • This proportion of approximately 15.85 cases per 100,000 women represents a public health problem.3 The quadrivalent vaccine for HPV (6,11,16 and 18) is considered to be one of the strategies to reduce cervical cancer 2,3 , with protection of between 80-100% vaccinates for anogenital warts and 60-80% in reducing new cases of pre-malignant lesions 2,4 . (bvsalud.org)
  • This study determined the immune correlates induced by serial dilutions of rAd vaccines delivered intramuscularly (IM) and intranasally (IN) to mice and rats. (mdpi.com)
  • A final vaccine analysis using a lethal influenza virus challenge showed that despite the differences in the immune responses observed in the mice, the mice had very similar patterns of protection. (mdpi.com)
  • Cancer vaccines are medicines that trigger the body's immune system to detect cancer cells. (canceraustralia.gov.au)
  • Treatment (therapeutic) vaccines prompt the immune system to fight existing cancer cells. (canceraustralia.gov.au)
  • Animal studies have shown that the iBioModulator platform can increase the strength of the immune response specific to a vaccine antigen (as measured by antibody titer). (globenewswire.com)
  • Hookipa's proprietary arenavirus-based technologies, VaxWave, a replication-deficient viral vector, and TheraT, a replication-attenuated viral vector, are designed to induce antigen specific cytotoxic T cells and pathogen-neutralizing antibodies for prophylactic and therapeutic purposes activating body's immune response. (pharmaceutical-technology.com)
  • Policymakers will need information on the epi- mavirus (HPV) vaccine in a setting of organized cervical demiologic and economic impact of HPV vaccination to cancer screening in the United States. (cdc.gov)
  • We used a transmission dynamic model to predict the burden of human papillomavirus related disease for the number of cervical screens, treatments for precancerous abnormalities of the cervix, and cases of diagnosed cancer and anogenital warts expected before and after vaccination. (bmj.com)
  • In many countries, vaccines against some human papillomavirus (HPV) types are now administered to girls and young women with the goal of protecting them against HPV-induced cervical cancer ( 1 , 2 ). (cdc.gov)
  • Women who have had the HPV vaccine should still start getting screened for cervical cancer when they reach age 21. (cdc.gov)
  • Human papillomavirus (HPV) is a major risk factor for several types of cancer including oropharyngeal cancer. (aacrjournals.org)
  • The main types of immunotherapy can be divided into treatments using monoclonal antibodies, nonspecific immunotherapies, and cancer vaccines. (canceraustralia.gov.au)
  • There are 2 types of cancer vaccines. (canceraustralia.gov.au)
  • For example, sipuleucel-T is a cancer vaccine used to treat prostate cancer. (canceraustralia.gov.au)
  • This trend, suggestive of a resurgence in cervical cancer, has also been observed in many European countries and could reflect increased cancer detection by the use of new diagnostic techniques, such as human papillomavirus (HPV) testing and cervicography, or it could be the result of a cohort effect. (cmaj.ca)
  • Based on our study it is suggested that a prophylactic vaccine based on a cocktail of a limited number of high-risk HPV types should be considered in order to protect most women from developing cervical cancer. (nih.gov)
  • The aim of this study was to assess the cost-effectiveness of adding vaccination with the human papillomavirus 16/18 vaccine to the current cervical cancer screening program in Hungary. (biomedcentral.com)
  • Our modeling analysis showed that the vaccination of 12-year-old adolescent girls against cervical cancer with the AS04-adjuvanted human papillomavirus 16/18 vaccine would be a cost-effective strategy to prevent cervical cancer in Hungary. (biomedcentral.com)
  • There are two vaccines available for preventing cervical cancer. (biomedcentral.com)
  • 3. Prophylactic HPV vaccines, besides protecting against cervical cancer, can also reduce the burden of screening for those with atypical squamous cells of undetermined significance. (hkmj.org)
  • Assessment of the pre-human papillomavirus (HPV) vaccination burden of ambulatory care visits and procedures related to cervical cancer screening is provided, with projection of how HPV vaccination and testing may affect this burden. (ajmc.com)
  • Human papillomavirus vaccination and testing may affect the volume of Pap tests and cervical cancer procedures in the future. (ajmc.com)
  • Human papillomavirus (HPV) testing, approved for routine cervical cancer screening in 2003, and the HPV vaccine, approved for routine vaccination of girls in 2006, are shifting the paradigm of cervical cancer screening and management. (ajmc.com)
  • Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen ), or therapeutic (to fight a disease that has already occurred, such as cancer ). (webot.org)
  • Human Papillomavirus (HPV) is the main responsible of one of the most common sexually transmitted diseases worldwide and persistent infection is the major risk factor for the development of cervical cancer. (biomedcentral.com)
  • 2011. Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway. (virosin.org)
  • Papillomaviruses: Viral evolution, cancer and evolutionary medicine. (virosin.org)
  • However, the benefits of prophylactic vaccines in a broad public health perspective will be achieved only if such vaccines can be provided to those groups of women for whom access to cervical cancer screening services is most problematic. (iarc.fr)
  • Identification of a genetic alteration may change recommendations for cancer screening, chemoprevention, and prophylactic surgery. (medscape.com)
  • administration of HPV vaccine, the du- in each region, 1 middle school from ration of protection, vaccine side-effects the large cities of the region and 1 from In Morocco, cervical cancer represents and the indications for males. (who.int)
  • Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors. (msdmanuals.com)
  • Although the strategy of ICE is risk (HR) HPV infection in the etiology of beta human papillomavirus (HPV) types global, work is natural y focused on low- head and neck cancer. (who.int)
  • Predictors of parents' acceptance of the HPV vaccine were living in precarious housing/slums and low household income (for mothers) and living in urban areas (for fathers). (who.int)
  • In order to move toward universal acceptance of the HPV vaccine by the general population, both … mandated HPV vaccination and HPV vaccination-specific issues must be addressed. (iospress.com)
  • Identifying and understanding factors associated with the acceptance of the HPV vaccine has been and will continue to be important so physicians can assist parents and adolescents in their decision to refuse or accept the vaccine. (iospress.com)
  • Behavioral factors significantly associated with lower acceptance of the HPV vaccine included lack of physical activity in the past month ( P = 0.002), past year use of complementary or alternative therapies ( P = 0.021), and no history of smoking ( P = 0.005). (aacrjournals.org)
  • Using previously described methods, 1,4,5,8,10 the UuPV1-virus-like particles produced in this process, were used as immunologic reagents to detect anti-UuPV1 antibodies, and hence determine the seroprevalence of papillomavirus infection in captive North American snow leopards. (vin.com)
  • The neutralizing antibodies elicited by human papillomavirus (HPV) major capsid protein L1 virus-like particle (VLP)-based vaccines are largely type-specific. (oncotarget.com)
  • An HPV vaccine inducing cross-neutralizing antibodies broadly will be cost-effective and of great value. (oncotarget.com)
  • Despite weak knowledge of genital warts and HPV infection, acceptability of the HPV vaccine was 76.8% (95% CI: 73.3-79.9%) among mothers and 68.9% (95% CI: 65.2-72.5%) among fathers. (who.int)
  • The primary purpose of the current study is to report on national acceptability of the HPV vaccine among U.S. adults with female children in the household and to investigate the health behavior correlates of vaccine acceptability. (aacrjournals.org)
  • Syrjänen, Kari 2008-06-26 00:00:00 Background: At present, seroreactivity is not a valuable parameter for diagnosis of Human Papillomavirus (HPV) infection but, it is potentially valuable as marker of viral exposure in elucidating the natural history of this infection. (sagepub.com)
  • The human papillomavirus (HPV) is a prevalent viral infection in the sexually active population, which can be oncogenic and non-oncogenic. (bvsalud.org)
  • In particular, vaccination will not tal cost-effectiveness ratio (ICER) of augmenting this only directly protect through vaccine-derived immunity but strategy with a temporary catch-up program for 12- to 24- also indirectly through herd immunity. (cdc.gov)
  • Objective To assess the cost effectiveness of routine vaccination of 12 year old schoolgirls against human papillomavirus infection in the United Kingdom. (bmj.com)
  • We describe the cost effectiveness model used to inform decisions about human papillomavirus vaccination in the UK. (bmj.com)
  • [1] [2] The safety and effectiveness of vaccines has been widely studied and verified. (webot.org)
  • Vaccine effectiveness was lower in girls who were not enrolled in school, and was also lower in girls living with HIV. (who.int)
  • Interpretation: A vaccine targeting HPV types 6, 11, 16, 18 could substantially reduce the acquisition of infection and clinical disease caused by common HPV types. (johnshopkins.edu)
  • Clinical trials continue into different types of therapeutic vaccines. (canceraustralia.gov.au)
  • These vaccines, however, prevent only four HPV types, two high-risk types (HPV 16, 18) and two low-risk types (HPV 6, 11). (who.int)
  • An uman papillomavirus (HPV) causes cervical intraep- online Supplementary Appendix (available from www. (cdc.gov)
  • Increased Antibody Responses to Human Papilloma Virus Type 16 L1 Protein Expressed by Recombinant Vaccine Virus Lacking Serine Protease Inhibitor Genes", Chemical Abstracts, Nov. 5, 1990, Vol. 13, No. 19 Zhou et al. (wikipedia.org)
  • Study of construct elaboration based on an empirical review of the literature with a qualitative focus on PubMed database, from 2007 to 2014, using the following keywords: Papillomaviridae AND Papillomavirus Vaccines AND Knowledge AND Community Health Services. (bvsalud.org)
  • The results were sensitive to the price of the vaccine, the discount rate, the screening participation rate and whether herd immunity was taken into account. (biomedcentral.com)
  • A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease. (webot.org)
  • Prophylactic vaccines for genital human papillomavirus (HPV) infection have been shown to be feasible in animal models, and suitable vaccine material based on virus-like particles can be produced in bulk at reasonable cost. (nih.gov)
  • Human papillomavirus 16L1-58L2 chimeric virus-like particles elicit durable neutralizing antibody responses against a broad-spectrum of human papillomavirus. (oncotarget.com)
  • The virosomal influenza vaccine Invivac: immunogenicity and tolerability compared to an adjuvanted influenza vaccine (Fluad in elderly subjects. (vakciny.net)
  • Thimerosal is currently used only in multidose vials of influenza vaccine, and exposure through vaccines is not associated with adverse neurologic outcomes. (aafp.org)
  • 1". Human Papillomaviruses: Clinical and Scientific Advances. (wikipedia.org)
  • His research has been in clinical paediatrics in adjustment to chronic illness and in incontinence, and in immunisation and clinical trials of new vaccines. (edu.au)
  • The fact that menstrual data was not collected during any of the clinical trials for the available COVID-19 vaccines means that people who menstruate simply didn't know how or if the vaccine might affect their cycles. (drugdiscoverynews.com)
  • Commercially available Papillomavirus Clinical Arrays ® kits (Genomica) were used to perform HPV genotyping. (biomedcentral.com)
  • Immunogenicity of 2 doses of HPV vaccine in younger adolescents vs 3 doses in young women: a randomized clinical trial. (virosin.org)
  • How could IM injection of a VLP vaccine prevent mucosal or cutaneous infection at the cervix? (hstalks.com)
  • Commercial applications of this proprietary platform include the development of more effective vaccines. (globenewswire.com)
  • The iBioModulator platform can be used with any recombinant expression technology for vaccine development and production. (globenewswire.com)
  • The development of peptide-based vaccines targeting group A streptococcus ( S. progenes ) is made difficult by the fact that there are over 200 different strains against which protection must be ensured. (moylelab.com)
  • Moyle PM, Olive C, Ho M-F, Pandey M, Dyer J, Suhrbier A, Fujita Y, Toth I. Toward the development of prophylactic and therapeutic human papillomavirus type-16 lipopeptide vaccines. (moylelab.com)
  • [17] The science of vaccine development and production is termed vaccinology . (webot.org)
  • about the natural history of papillomaviruses in rabbits and how they can be transmitted through the mouth and how they can remain there. (cdc.gov)
  • The measles, mumps, and rubella vaccine is not associated with autism. (aafp.org)
  • The measles, mumps, and rubella vaccine does not increase the risk of autism and should be routinely used. (aafp.org)
  • Other vaccinations for adults include rubella, HPV (human papillomavirus), hepatitis A or B, and pneumococcus. (fortherecordmag.com)
  • 4 Because of this, adolescents should be observed for 15 minutes after receiving these vaccines. (aafp.org)
  • Educational efforts by health professionals, aimed at adolescents and their parents, help decision-making on human papillomavirus vaccination, benefiting the implantation process and vaccine coverage. (bvsalud.org)
  • To describe the data collection constructs about knowledge and acceptability of HPV vaccine among adolescents, parents and health professionals. (bvsalud.org)
  • The instrument was adequate to measure knowledge about HPV, its repercussions and its vaccine among adolescents, parents/guardians and health professionals, as well as measuring the acceptability of the human papillomavirus vaccine. (bvsalud.org)
  • Prior studies have examined demographic, medical history, and psychosocial variables associated with parental HPV vaccine acceptability, although few have investigated the behavioral correlates of vaccine acceptability. (aacrjournals.org)
  • The invention relates to human papillomavirus like particles (VLPs) and their use as therapeutic agents. (justia.com)
  • These results will be useful for preparing the introduction of the HPV vaccine in health ministry programmes. (who.int)
  • In the UK the Department of Health has announced a routine human papillomavirus immunisation programme for schoolgirls aged 12 or 13, starting from September 2008, with a two year catch-up programme for girls up to 18. (bmj.com)
  • ACIP recommends either vaccine for routine use in females aged 11 or 12 years ( 3 ). (cdc.gov)
  • 7-10 In developed countries such as the United States of America, vaccines against HPV were recommended for routine use in females aged 11 to 12 years. (who.int)