Properties of hydrogels. Medical search. Frequent questions

Among different types of scaffolds, polymeric hydrogel scaffolds have received considerable attention because of their biocompatibility and structural similarity to native tissues. (mdpi.com)
For the application of advanced hydrogel-based artificial muscle systems, conventional polymeric hydrogels usually suffer from various limitations such as structural inhomogeneity and poor mechanical strengths. (lboro.ac.uk)
DNA is a perfect polymeric molecule for interfacing biology with material science to construct hydrogels with fascinating properties for a wide variety of biomedical applications. (helsinki.fi)
In these efforts, hydrogels - three-dimensional cross-linked polymeric networks - are among the most promising nature-derived materials applied in recent technologies for biomedical engineering, biotechnology, packaging, pharmaceutical science and agriculture. (materialstoday.com)

In this study, the hydrophobic drug Tanshinone ⅡA (Tan ⅡA) as a therapeutic drug was loaded into naphthalene acetic acid-phenylalanine-phenylalanine-glycine hydrogel (Nap-FFG) to construct the supramolecular hydrogels. (jascoinc.com)
Self-assembled peptide supramolecular hydrogels have shown great application prospects in various areas, including tissue engineering, drug delivery, and biosensing. (cas.cn)
The common methods to regulate the mechanical properties of supramolecular hydrogels generally include: changing the formula (different peptide sequences, adding cross-linking agents) or changing the environmental conditions (concentration, temperature, pH and ions), both of which inevitably change the chemical composition of the hydrogel. (cas.cn)
Supramolecular hydrogels formed by the self-assembly of N-Fmoc-L-phenylalanine derivatives are gaining relevance for several applications in the materials and biomedical fields. (suprabionano.eu)

Montheil T, Echalier C, Martinez J, Subra G, Mehdi A. Inorganic polymerization: an attractive route to biocompatible hybrid hydrogels. (nature.com)
Preparation and enhanced mechanical properties of hybrid hydrogels comprising ultralong hydroxyapatite nanowires and sodium alginate. (nature.com)
The current proof-of-concept work should be just the start for exploring many other hybrid hydrogels that could exploit the unique properties of other natural systems. (sciencedaily.com)

Unique molecular interactions between graphene derivatives and various small or macromolecules enable the fabrication of various functional hydrogels appropriate for different biomedical applications. (nature.com)
In this mini-review, we highlight the recent progress in GO-incorporated hydrogels for biomedical applications while focusing on their specific uses as mechanically strong materials, electrically conductive scaffolds/electrodes, and high-performance drug delivery vehicles. (nature.com)
Recent developments in tough hydrogels for biomedical applications. (nature.com)
Hydrogels for biomedical applications. (nature.com)
Chai Q, Jiao Y, Yu X. Hydrogels for biomedical applications: their characteristics and the mechanisms behind them. (nature.com)
Biomedical applications of hydrogels: a review of patents and commercial products. (nature.com)
Self-assembling natural drug hydrogels formed without structural modification and able to act as carriers are of interest for biomedical applications. (nature.com)
Water uptake property of hydrogels or "hungry networks" accounts for a great number of biomedical and technological applications. (scirp.org)
Hydrogels are well-established as excellent candidates for biomedical applications , including wound treatment, tissue engineering and controlled drug release. (stfc.ac.uk)
Mohammad-Ali Shahbazi, Tomás Bauleth-Ramos, Hélder A. Santos*, " DNA Hydrogel Assemblies: Bridging Synthesis Principles to Biomedical Applications ", Adv. Ther. (helsinki.fi)
In addition, potential usages of DNA hydrogels for different biomedical applications are highlighted by giving different examples of efforts intending to bring the molecule of DNA into the realm of bulk materials. (helsinki.fi)
8,9 3D printing of nanocellulose hydrogels is being used in biomedical applications to support living cell growth for tissue engineering, implants, and cardiovascular devices. (cdc.gov)

Despite significant progress in developing hydrogel-based flexible electronics, several challenges remain. (nanowerk.com)

Creep indentation experiments were therefore performed on samples of the hydrogel. (bath.ac.uk)
Freeze-dried samples of the hydrogel show a mesoporous network of polycarboxylate ligands that are crosslinked by silver(i) cations. (edu.sa)

Thus, chemists and pharmacologists persistently desire to prepare directed self-assemble hydrogels, referring to self-delivering, self-releasing, stable, injectable and stimuli-responsive hydrogels without any structural modification and delivery cargoes. (nature.com)

Hydrogels are three-dimensional networks consisting of chemically or physically cross-linked hydrophilic polymers. (wikipedia.org)
To address this issue, researchers have explored various approaches, such as incorporating conductive fillers or dopants, selecting hydrogels made of conductive polymers, and introducing a double-network strategy that combines both conductive and non-conductive elements within the hydrogel structure. (nanowerk.com)
Researchers at Hokkaido University in Japan have combined natural squid tissues with synthetic polymers to develop a strong and versatile hydrogel that mimics many of the unique properties of biological tissues. (sciencedaily.com)
By combining the properties of tissues derived from squid with synthetic polymers, we have demonstrated a hybrid strategy that serves as a general method for preparing hydrogels with useful hierarchical anisotropy and also toughness," says polymer scientist Tasuku Nakajima of the Hokkaido University team. (sciencedaily.com)
Novel functional materials such as composite polymers are new materials which have produced properties wanted through the development of specialized areas. (scirp.org)
Hydrogels are crosslinked hydrophilic polymers that undergo swelling in water. (uwaterloo.ca)
While synthetic- and bio-polymers are used extensively as building blocks in hydrogels, the potential of folded and functional protein-based hydrogels is just beginning to emerge. (stfc.ac.uk)
However, the mechanical properties of conductive polymers are not ideal, as they are quite brittle. (frontiersin.org)
Hydrogel polymers present a versatile coating option for electrodes as they can be chemically modified to provide a soft and conductive scaffold. (frontiersin.org)
With their function as biomimetic material, synthetic hydrogels or hydrogel-forming natural polymers (e.g. collagen, alginate or agarose) are utilized to reproduce the filamentous nature and properties of extracellular matrix serving as scaffolds for 3D cell culture, artificial skin, actuators, biosensors, drug delivery vehicles and tissue-engineered products for cell matrices [4] . (materialstoday.com)

Hydrogel dressings can be designed to prevent bacterial infection, retain moisture, promote optimum adhesion to tissues, and satisfy the basic requirements of biocompatibility. (wikipedia.org)
DNA is an irreplaceable building block for the construction of novel 3D hydrogels, because of its multifunctional tunability, convenient programmability, adequate biocompatibility, biodegradability, capability of precise molecular recognition, and high versatility. (helsinki.fi)

In the preparation of hydrogels, the number and size of phase-separated droplets are well-controlled in the early stage of self-assembly in order to tune the nanostructure of self-assembled precursors. (cas.cn)
For the preparation of hydrogels, physical and chemical polymerization and crosslinking methods are traditionally involved. (materialstoday.com)

Some hydrogel dressings have incorporated stimuli-responsive nitric oxide-releasing agents and other antimicrobial agents. (wikipedia.org)
Fabrication of a Responsive Hydrogel Photonic Crystal Sensing Film for Cadmium Ions [J]. Acta Phys. (pku.edu.cn)
This understanding can pave the way for further development of flexible electronics using environmentally responsive hydrogels. (nanowerk.com)
The key design parameters to achieve responsive DNA hydrogels are discussed and challenges of DNA hydrogel fabrication are addressed from biological point of view. (helsinki.fi)
Responsive Hydrogel Colloids: Structure, Interactions, Phase Behaviour and Equilibrium and Non-equilibrium Transitions of Microgel Dispersions. (lu.se)

Our findings are confirmed by Monte Carlo simulations of the formation and mechanical response of hydrogels with different molecular interactions. (confex.com)
Here, we report on rhein, a herbal natural product, which is directly self-assembled into hydrogels through noncovalent interactions. (nature.com)
Physically cross-linked hydrogel dressings are assembled via ionic interaction, hydrogen bonding, hydrophobic interactions, or crystallization. (wikipedia.org)
Hydrogels can be formed through a self-assembly process in which monomers diffuse in solution then form non covalent interactions. (wikipedia.org)
citation needed] Hydrogels used in wound dressings can be self-assembled upon addition of divalent metal cations or electrically charged polysaccharides due to electrostatic interactions. (wikipedia.org)
The adhesive properties of hydrogels have been shown to be enhanced by addition of positively charged microgels (MR) into the 3D matrix to increase electrostatic and hydrophobic interactions. (wikipedia.org)
Various methods have been investigated for realizing self-healing in hydrogels, which can be categorized under two major approaches: those based on dynamic covalent bonds that can reversibly form and break, and those based on noncovalent bonds, such as hydrogen bonding or ionic interactions. (nanowerk.com)

In this work, we developed a postpolymerization coupling strategy to conjugate short DNA sequences to polyacrylamide-based hydrogel blocks. (nih.gov)
Chemical and heat treatment of thin slices of the defrosted squid tissue mixed with polyacrylamide polymer molecules initiated formation of the cross-linked hybrid hydrogel. (sciencedaily.com)

Hydrogels have emerged as a promising candidate for developing bioelectronics, which interface living biological tissues with synthetic electronic systems. (nanowerk.com)
These hydrogels closely mimic the mechanical, chemical, and optical properties of biological tissues, making them ideal for use in flexible electronic devices. (nanowerk.com)
As a result, hydrogel-based flexible electronics can better conform and interact with biological tissues and organisms than traditional electronic components, which are often rigid, dry, or incompatible with human tissues. (nanowerk.com)
Natural biological tissues exhibit unique properties essential for their functions, which researchers are seeking to replicate in hydrogels. (sciencedaily.com)
A major challenge is understanding how the properties of the biological building block, such as the folded protein, translates to the macroscopic properties of the protein network. (stfc.ac.uk)

The researchers knew from toxicity literature that their hydrogel capsules would be biocompatible, and would behave in a syringe. (nanowerk.com)

Natural hydrogel dressings are further subdivided into either polysaccharide-based (e.g. alginates) or proteoglycan- and/or protein-based (e.g. collagen). (wikipedia.org)
MatriMix also contains medical grade porcine collagens, streamlining the transition from basic to clinical research unlike any existing natural hydrogel. (labx.com)
As Mo3Se3- chain nanowires have dimensions comparable to those of natural hydrogel chains (molecular-level diameters of 0.6 nm and lengths of several micrometers) and excellent mechanical strength and flexibility, they have large potential to reinforce hydrogels and improve their mechanical properties. (tamu.edu)

In this context, the latest methods for synthesizing functional hydrogels and their applications in various fields have been reviewed in Advanced Materials ( 'Hydrogel-Based Flexible Electronics' ), highlighting the relationship between hydrogel properties and device performance. (nanowerk.com)

The hydrogel is prepared conveniently with hydroxyethyl acrylate, cross-linker, gelatin and photoinitiator, and can be printed into certain 3D patterns with the direct ink write (DIW) 3D printer designed and developed by the research group.Design/methodology/approachIn this paper, the authors designed a composite sensitization initiation system that is suitable for hydrogels. (deepdyve.com)
The concentration of photoinitiator, gelatin and cross-linker was studied to optimize the curing efficiency and adjust the mechanical properties. (deepdyve.com)
While adding various content of gelatin and cross-linker, the mechanical properties of hydrogels show from soft and fragile (elastic modulus of 121.18 kPa and work of tension of 218.11 kJ·m−3) to rigid and tough (elastic modulus of 505.15 kPa and work of tension of 969.00 kJ·m−3). (deepdyve.com)
Characterization studies were performed using physically and chemically crosslinked hydrogel systems, including gelatin hydrogels (6-10 wt. (aip.org)
Chemical and physical treatments can be used to modify the gelatin network by establishing cross-links between the gelatin chains to improve the properties of the gel. (ac.ir)
The effect of CA and TA concentrations on the physicochemical properties of gelatin hydrogels was investigated. (ac.ir)
Scanning electron microscopy images of the hydrogel samples showed that the structure of the hydrogels based on cold-water fish gelatin was spongy. (ac.ir)
When a Mo3Se3--chain-nanowire-gelatin composite hydrogel is prepared simply by mixing Mo3Se3- nanowires with gelatin, phase separation of the Mo3Se3- nanowires from the gelatin matrix occurs in the micronetwork, providing only small improvements in their mechanical properties. (tamu.edu)
In contrast, when the surface of the Mo3Se3- nanowire is wrapped with the gelatin polymer, the chemical compatibility of the Mo3Se3- nanowire with the gelatin matrix is significantly improved, which enables the fabrication of a phase-separation-free Mo3Se3--reinforced gelatin hydrogel. (tamu.edu)
The composite gelatin hydrogel exhibits significantly improved mechanical properties, including a tensile strength of 27.6 kPa, fracture toughness of 26.9 kJ/m3, and elastic modulus of 54.8 kPa, which are 367%, 868%, and 378% higher than those of the pure gelatin hydrogel, respectively. (tamu.edu)

Hydrogel dressings mimic the cross-linked 3D network of extracellular matrix fibers in human skin. (wikipedia.org)
Unlike the natural tissues that researchers wish to mimic, most synthetic hydrogels have uniform properties in all directions and are structurally weak. (sciencedaily.com)
Depending on their composition, water-based gels can closely mimic the physical properties of a range of tissues. (uwo.ca)

Furthermore, different concentrations of this polymer led to a range of hydrogels with shear moduli ranging from 10(5) Pa down to less than 10(2) Pa, similar to the soft tissues in the body. (ox.ac.uk)
The rheological assay of Tan ⅡA-loaded Nap-FFG hydrogel (Tan@Nap-FFG) had excellent shear resistance, allowing it to maintain gel state. (jascoinc.com)
Q air = 23.8 ± 1.5) enabled continuous monitoring of high-frequency hydrogel shear storage and loss moduli ( G′ f and G″ f , respectively) calculated by sensor data and fluid-structure interaction models. (aip.org)
Such timescales allow sufficient mixing of cells and hydrogel precursors under low shear forces and the achievement of homogeneous networks and cell distributions in the 3D cell culture . (bvsalud.org)
These bioinks are shear thinning, resist cell sedimentation, improve viability of multiple cell types, and enhance mechanical stability in hydrogels derived from them. (lu.se)

Additionally, the review provides insights into current challenges and future directions for developing multifunctional hydrogel-based flexible electronics, which can enhance the performance and scope of applications in this emerging field. (nanowerk.com)
Highly swollen crosslinked hydrophilic copolymers called "hydrogels" are synthesized by free radical crosslinking copolymerization with some multifunctional crosslinkers with some co-monomers including hydrophilic groups for increasing of their swelling capacity. (scirp.org)
The enormous diversity provided by the design of multifunctional hydrogels is realized by combining hierarchical structuring inspired by nature with the variety of materials available by engineering are of utmost significance for the desired application. (materialstoday.com)

Hydrogels are effective biomaterials for wound dressings and tissue engineering because they exchange fluid, hydrating necrotic tissues. (wikipedia.org)
Composite stems combine the physical properties of alloys with those of other biomaterials. (medscape.com)

The same synthon occurred in the transparent gels formed by mixing the two components in 1:1 ratio in aqueous media, as revealed by structural, spectroscopic, and thermal characterizations performed on both the co-crystal powder and the lyophilized hydrogel. (suprabionano.eu)
Composite gels made from a cross-linked mixture of chitosan and BSA exhibited the swelling behavior of BSA combined with the mechanical properties of chitosan and were therefore considered most suitable for use in a gastric environment. (uea.ac.uk)
The gels demonstrated responsiveness to UV light exposure through measurement of their degradation products and their physical properties were determined through a series of tests that involved swelling the gels in a phosphate-buffered saline solution. (uwo.ca)

A de novo designed β-hairpin peptide (MAX8), capable of undergoing intramolecular folding and consequent intermolecular self-assembly into a cytocompatible hydrogel, has been studied. (rsc.org)
Self-assembling designer peptide hydrogels are another type of synthetic hydrogel in development. (wikipedia.org)
Precisely and flexibly controlling the mechanical properties of peptide hydrogels to match the targeted applications is important. (cas.cn)
They further confirmed through experiments and molecular simulation that at the phase transition temperature, peptide molecules showed a strong aggregation propensity, de-solvation effect, and dynamic metastable hydrogen bonding, which was conducive to fibril branching, thus enabling the hydrogel to obtain the best nanofibril strength and cross-linking density under the condition of constant concentration. (cas.cn)
The use of hybrid self-assembling peptide (EFK8)-carbon nanotube (SWNT) hydrogels for tissue engineering and in vitro 3D cancer spheroid formation is reported. (uwaterloo.ca)

Hydrogel dressings can be sorted into the categories: synthetic, natural, and hybrid. (wikipedia.org)
Synthetic hydrogel dressings have been produced using biomimetic extracellular matrix nanofibers such as polyvinyl alcohol (PVA). (wikipedia.org)
Hybrid hydrogel dressings incorporate synthetic nanoparticles and natural materials. (wikipedia.org)

Hydrogels incorporating nanoparticles (NPs) possess new properties that can revolutionize areas such as drug delivery, protein crystallography, and self-assembly of photonic crystals. (confex.com)
The antimicrobial properties of hydrogel dressings can be enhanced by addition of metal nanoparticles, antibiotics, or other antimicrobial agents. (wikipedia.org)
Silver and gold nanoparticles can also be incorporated into hydrogel dressings to enhance antimicrobial activity. (wikipedia.org)

However, hydrogel scaffolds have several limitations, such as weak mechanical property and a lack of bioactive property. (mdpi.com)

MIT engineers have now found that polyethylene glycol (PEG) - a hydrogel commonly used in cosmetic creams, industrial coatings, and pharmaceutical capsules - can absorb moisture from the atmosphere even as temperatures climb. (sflorg.com)
A more recent approach proposes tissue engineering the electrode interface through the use of encapsulated neurons within hydrogel coatings. (frontiersin.org)
Here, we report on the fabrication of hydrogel coatings by using non-thermal gas discharges, referred to as plasma, a gaseous state in which free electrons and ionized atoms exist. (materialstoday.com)

Graphene and graphene derivatives (e.g., graphene oxide (GO)) have been incorporated into hydrogels to improve the properties (e.g., mechanical strength) of conventional hydrogels and/or develop new functions (e.g., electrical conductivity and drug loading/delivery). (nature.com)
When it comes to further fibril growth and formation of a non-covalent cross-linking network, the structural difference between precursors leads to a difference in fibril diameter, number of fibrils, and cross-linking density of the network, thus forming hydrogel materials with different mechanical strength and recoverability. (cas.cn)
An optimal initial incubation temperature could lead to optimal mechanical strength and recoverability when the chemical composition of the hydrogel remained unchanged. (cas.cn)
Thus, improving the mechanical strength of a specific hydrogel system while maintaining its other useful properties become increasingly important. (lboro.ac.uk)
The group found that they were able to translate this stability of the protein building block into the cross-linked folded protein hydrogel , which showed increased mechanical strength. (stfc.ac.uk)

Technological exploited plasmas, inspired by natural atmospheric discharges, offers unique capabilities of surface engineering including modifying selected surface properties and enabling surface functionalization along with the fabrication of special surface structures. (materialstoday.com)

With the DIW 3D printer, pre-gel hydrogel solution can be printed into objects with certain dimension.Originality/valueIn this work, a composite sensitization initiation system was designed, and fast curing hydrogels with adjustable mechanical properties had been prepared conveniently, which has high equilibrium water content and 3D printability with the DIW 3D printer. (deepdyve.com)
The improvements in the mechanical properties are significantly larger than those for other reported composite hydrogels reinforced with one-dimensional materials. (tamu.edu)
For instance, embedding nanomaterials into 3D printed composites can enhance the properties of these complex parts, extending composite capabilities for electrical/thermal gradients, increasing strength, and decreasing overall weight. (cdc.gov)
Note, ceramic or metal femoral heads are used on composite hip stems because composites have relatively poor wear properties. (medscape.com)

Toward this end, we first confirm that the differentiation profile of MSCs cultured in 2D on highly elastic, covalently crosslinked poly(ethylene glycol) diacrylate (PEGDA) hydrogels differs substantially from that of MSCs encapsulated within the same hydrogel formulations, indicating a dependence in 3D on a variable(s) beyond elastic modulus. (unab.edu.co)
It was found that formulations of higher polymer content produced hydrogels that degraded upon UV light irradiation, showing promise for future applications. (uwo.ca)

Collagen-Poly(N-isopropylacrylamide) Hydrogels with Tunable Properties. (ox.ac.uk)
We have demonstrated that by combining collagen with a thermoresponsive polymer, poly(N-isopropylacrylamide) (PNIPAM), the mechanical properties can be improved while maintaining cytocompatibility. (ox.ac.uk)

Bovine chrondrocytes, seeded in hydrogels, were used to asses the cell responses tp the hydrogels. (nist.gov)
Experimental and theoretical investigations of the swelling and mechanical properties of hydrogels formed from chitosan, bovine serum albumin (BSA), and chitosan/BSA mixtures cross-linked with genipin were performed. (uea.ac.uk)

The resulting hydrogels are cytocompatible and stable in cell culture conditions. (bvsalud.org)

Aim: Due to the various drawbacks associated with current treatment therapy of onychomycosis, the main aim was to develop thermosensitive hydrogels and thermosensitive polypseudorotaxanes hydrogels-based nail lacquer for transungual delivery of Efinaconazole for the management of onychomycosis. (eurekaselect.com)

Professor Lorna Dougan, University of Leeds, who leads the project said "Harnessing an understanding of the hierarchical biomechanics of folded proteins to create a programmable hydrogel would create transformative technology . (stfc.ac.uk)
Furthermore, by applying plasma technology, the route of chemical reactions is modified, which enables a high level of functionality as well as the formation of a hierarchical structure of the fabricated hydrogel coating. (materialstoday.com)

Here, we present data indicating that hydrogel elastic modulus and mesh size regulate MSC differentiation in part through modulating the activity of the metabolic enzyme glyceraldehyde-3-phosphate-dehydrogenase (GAPDH). (unab.edu.co)
Further results indicate that the GAPDH activity of MSCs in 3D hydrogels is a function of elastic modulus and mesh size, suggesting that GAPDH activity may be one of these variables. (unab.edu.co)
Studies in 2D supported a positive correlation between hydrogel elastic modulus and GAPDH activity. (unab.edu.co)
Methacryloyl-substituted tropoelastin , or MeTro, is an elastic hydrogel compound that can be applied to internal or external wounds during surgery or in emergency situations. (thedoctorschannel.com)

Our previous work showed that the thiol -tetrazole methylsulfone (TzMS) reaction crosslinks star-poly( ethylene glycol ) (PEG) hydrogels within minutes at around physiological pH and can be accelerated or slowed down with small pH changes. (bvsalud.org)
By addition of AgNO 3-solution, the formation of the silver(i) supramolecular polymer hydrogel poly[methyl vinyl ether-alt-mono-sodium maleate]·AgNO 3 is reported. (edu.sa)
Poly(ethyl glyoxylate) (PEtG) is a SIP that can be modified to adjust its physical and thermal properties. (uwo.ca)

Hydrogels are three-dimensional networks of hydrophilic polymer chains with properties in between liquids and solids. (scirp.org)
Hydrogels are cross-linked hydrophilic polymer networks with low optical background and high loading capacity for immobilization of biomolecules. (uwaterloo.ca)

Chemically cross-linked hydrogel dressings are synthesized by chain-growth polymerization, step-growth polymerization, enzymes, or irradiation polymerization. (wikipedia.org)

Hydrogel: preparation, characterization, and applications: a review. (nature.com)
Here, we report for the first time that resonance in dynamic-mode cantilever sensors persists in hydrogels and enables the real-time characterization of hydrogel viscoelastic properties and the continuous monitoring of sol-gel phase transitions (i.e., gelation and dissolution processes). (aip.org)
The current study includes the preparation/characterization of a series of polyethylen glycol (PEG) dimethacrylate, their conversions in aqueous solution to photopolymerization, and a preliminary assessment of the correlation of mechanical and cell response to hydrogel structural variations. (nist.gov)

Nap-FFG hydrogel fibers crosslinked into a network-like structure by self-assembly of polypeptides and then achieved drug loading. (jascoinc.com)

The absorption of secretions causes the hydrogel dressing to swell, expanding the cross links in the polymer chains. (wikipedia.org)
cross-linking of the polymer chains into a polymer network while preserving the hydrogel structure. (materialstoday.com)

Hydrogel wound dressings are designed to have a mechanism for application and removal which minimizes further trauma to tissues. (wikipedia.org)
The natural abilities of squid tissues and the creativity of chemists combine to take hydrogel research in new directions. (sciencedaily.com)

HEMA and DEAEMA were selected due to the presence of polymerizable structures (e.g. vinyl groups) and because of their capacities to undergo hydrogen bonding in the plasma-polymerized film leading to inter- and intramolecular cross-linking to maintain the integrity of the hydrogel, in addition to conventional cross-linking reactions during plasma polymerization, resulting in complex networked structures. (materialstoday.com)

Some hydrogel dressings have intrinsic antimicrobial properties. (wikipedia.org)
In a display of modern-day alchemy, researchers at the University of Warwick in the UK have shown that a touch of gold - or another noble metal - can change the structure of a crystal and thus alter its intrinsic properties. (materialstoday.com)
Generally, the properties of these crystals are determined by two factors: the intrinsic properties of the elements that the crystal consists of, and how those elements are arranged to form that crystal, which we call its symmetry,' explained Mingmin Yang, who conducted the work at the University of Warwick and has since moved to the RIKEN Institute in Japan. (materialstoday.com)
1989a) was used to curve-fit the experimental data to theoretical solutions in order to extract the three intrinsic biphasic material properties of the hydrogel (aggregate modulus, HA, Poisson's ratio, Vs, and permeability, k). (bath.ac.uk)

Functionalized carbon nanotube and graphene oxide embedded electrically conductive hydrogel synergistically stimulates nerve cell differentiation. (nature.com)
However, the potential impact of biomaterial properties on regulating MSC differentiation through modulating cell metabolism is relatively unstudied. (unab.edu.co)
Cumulatively, these findings suggest that the potential impact of hydrogel properties on cell metabolism should be considered when evaluating biomaterial-driven MSC differentiation. (unab.edu.co)

Our studies corroborate that thiol /PEG-4TzMS hydrogels show gelation times and stiffnesses that are suitable for 3D cell encapsulation and tunable through changes in hydrogel composition. (bvsalud.org)

Using small angle neutron scattering on LOQ and ZOOM, and small-angle X-ray scattering in the ISIS Materials Characterisation Laboratory, the researchers were able to see that the differences in the mechanical properties of the gel were not due to a mesoscopic structural change in the protein network. (stfc.ac.uk)

A key requirement for their successful utilization into many target applications is the understanding of how the spatial arrangement of the NPs contributes to the mechanical properties of the hydrogel. (confex.com)
Bahram M, Mohseni N, Moghtader M. An introduction to hydrogels and some recent applications. (nature.com)
In: Emerging concepts in analysis and applications of hydrogels. (nature.com)
Fu J, In Het Panhuis M. Hydrogel properties and applications. (nature.com)
Song F, Li X, Wang Q, Liao L, Zhang C. Nanocomposite hydrogels and their applications in drug delivery and tissue engineering. (nature.com)
The Global Market for Hydrogels 2024-2034 provides a comprehensive analysis of the global hydrogel landscape, technologies, companies, and applications across major industry verticals. (researchandmarkets.com)
This study serves as a strategic guide for companies and investors looking to capitalize on the major growth opportunities for hydrogels across a diverse set of high-potential markets and applications. (researchandmarkets.com)
Main features of hydrogels and their applications in flexible electronics. (nanowerk.com)
The review provides a detailed overview of hydrogels, approaches to boost hydrogen functionality, and applications of hydrogel-based flexible electronics such as sensors, energy harvesting and storage devices, actuators, transistors, electromagnetic shielding, touch creens, and devices for controlled drug release. (nanowerk.com)
A hydrogel with potential applications in the role of a cushion form replacement joint bearing surface material has been investigated. (bath.ac.uk)
Recently, hydrogels have been used for controlled release applications. (uwaterloo.ca)
Further investigation into these hydrogels' physical properties is warranted to understand their potential applications fully. (uwo.ca)
These materials have new or unique properties different from those of larger forms of the same material, making them desirable for specific product applications. (cdc.gov)

Hydrogel dressings formed from antimicrobial peptides (AMPs) and chitosan have inherent antimicrobial activity. (wikipedia.org)
The properties of cross-linked chitosan hydrogels were explained in terms of its polyelectrolyte behavior, which led to a gradual increase in swelling ratio below the pK value, but whereby its swelling ability was eliminated by the presence of salt that screened the charges. (uea.ac.uk)

Properties and synthesis methods. (globenewswire.com)

Hydrogel dressings should possess mechanical and physical properties similar to the 3D microenvironment of the extracellular matrix of human skin. (wikipedia.org)

This study highlights a direct self-assembly hydrogel from natural small molecule as a promising neuroinflammatory therapy. (nature.com)
Cross-linked BSA hydrogels swelled even in the presence of salt, and a marked increase in swelling was observed below pH = 3 that was explained as the result of an acid induced denaturation of the protein that led to unfolding of the molecule. (uea.ac.uk)
These materials are composed of three key components: 1) many repeating units of the same molecule linked together in a chain, 2) molecules attached to each repeat unit that can change the properties of the overall molecule, and 3) a molecule at the end of the chain that can trigger degradation. (uwo.ca)

The role of graphene materials in the final structure of hydrogels. (nature.com)
Some hydrogel dressings have antibiotics such as ciprofloxacin and amoxicillin incorporated into their structure which are unloaded into the wound as fluid is exchanged. (wikipedia.org)
This study is designated to better understand the relationships between polymer matrix structure and properties to cell response. (nist.gov)
Forced together, pembro molecules become unstable and change their structure, undermining their therapeutic properties. (nanowerk.com)
As well as finding this increase in strength, the group were able to see other effects of maltose binding, and determine the structure of the hydrogel . (stfc.ac.uk)
Here we report on the gelation kinetics and mechanical properties of PEG-based hydrogels formed by thiol -TzMS crosslinking as a function of buffer , crosslinker structure and degree of TzMS functionality. (bvsalud.org)
2 µm) plasma-polymerized hydrogel film that represents a feather-like surface structure accompanied with a coloration resulting from a variation in the film's thickness. (materialstoday.com)

Equilibrium water swelling tests as well as uniaxial compression measurements were conducted to evaluate the influences of various experimental parameters on the hydrogels water-holding and mechanical properties. (lboro.ac.uk)

By analytically investigating the ratio of configurational transformations from three-point to single-point bonding, we demonstrate how the macro-mechanical properties of NP hydrogels can be influenced by the configurable coordination between molecules. (confex.com)
Despite these endeavors, designing directed self-assemble hydrogels formed by natural small molecules is still a formidable challenge. (nature.com)
Such crystal engineering-based approach is demonstrated to be also useful for the time-delayed release of suitable bioactive molecules, when involved as hydrogel coformers. (suprabionano.eu)

3D SnO 2 /Graphene Hydrogel Anode Material for Lithium-Ion Battery [J]. Acta Phys. (pku.edu.cn)
In this context, Xiangfeng Duan and his team at the University of California, Los Angeles, report on the preparation of a graphene hydrogel, which can be easily converted into solvated graphene frameworks. (phys.org)
To prepare the graphene frameworks, the scientists used a modified hydrothermal method to generate free-standing cubes of a graphene hydrogel from graphite oxide. (phys.org)
Simple solvent exchange then converted the hydrogel structures into the 3D solvated graphene frameworks, which could be readily pressed in films needed for LIB coin cells without losing their porous graphene network. (phys.org)

Anatomy3

Chemicals and Drugs26

Analytical, Diagnostic and Therapeutic Techniques and Equipment11

Phenomena and Processes11

Disciplines and Occupations2

Technology, Industry, Agriculture13

Polymeric4

Supramolecular hydrogels4

Hybrid hydrogels3

Biomedical12

Developing hydrogel-based1

Samples of the hydrogel2

Stimuli-responsive hydrogels1

Polymers10

Biocompatibility2

Preparation of hydrogels2

Responsive5

Interactions7

Polyacrylamide2

Biological5

Toxicity1

Natural hydrogel3

Functional hydrogels1

Gelatin10

Mimic3

Shear5

Multifunctional3

Biomaterials2

Gels3

Peptide5

Synthetic3

Nanoparticles3

Scaffolds1

Coatings3

Mechanical strength5

Fabrication1

Composite4

Formulations2

Collagen2

Bovine2

Cytocompatible1

Thermosensitive1

Hierarchical2

Elastic4

Poly3

Hydrophilic polymer2

Chemically1

Characterization3

Fibers1

Polymer chains2

Tissues2

Conventional1

Intrinsic4

Differentiation3

Tunable1

Structural1

Applications13

Chitosan2

Synthesis methods1

Extracellular matrix1

Molecule3

Structure7

Equilibrium1

Molecules3

Graphene4