AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
Leukemia, Promyelocytic, AcuteOxidesArsenicalsTretinoinHL-60 CellsOncogene Proteins, FusionIntranuclear Inclusion BodiesChromosomes, Human, Pair 15Neoplasm ProteinsChromosomes, Human, Pair 17Receptors, Retinoic AcidCell Nucleus StructuresTumor Suppressor ProteinsGranulocyte Precursor CellsNuclear ProteinsCell DifferentiationLeukemia, Myeloid, AcuteTranslocation, GeneticTranscription FactorsDimethyl SulfoxideIdarubicinGranulocytesTumor Cells, CulturedGene Expression Regulation, LeukemicKruppel-Like Transcription FactorsAntineoplastic AgentsLeukemia, MyeloidRemission InductionCell LineSUMO-1 ProteinCytarabineU937 CellsConsolidation ChemotherapyCell NucleusApoptosisDisseminated Intravascular CoagulationZinc FingersDaunorubicinTetradecanoylphorbol AcetateCell DivisionBone MarrowCalcitriolRNA, MessengerNitroblue TetrazoliumSmall Ubiquitin-Related Modifier ProteinsLeukemiaAntigens, NuclearCell Line, TumorTranscription, GeneticChromosomes, Human, 16-18RetinoidsIntranuclear SpaceDNA-Binding ProteinsDrug SynergismSaururaceaeThioguanineLeukocytosisKaryotypingAntineoplastic Combined Chemotherapy ProtocolsMolecular Sequence DataDimethylformamideDNA, Neoplasm6-MercaptopurineCarrier ProteinsBase SequenceFlow CytometryNuclear MatrixAnthracyclinesAntibiotics, AntineoplasticDrug Resistance, NeoplasmPhorbolsfms-Like Tyrosine Kinase 3RecurrenceRNA, NeoplasmProtein BindingRecombinant Fusion ProteinsPreleukemiaSialic Acid Binding Ig-like Lectin 3Reverse Transcriptase Polymerase Chain ReactionSumoylationCell CycleTransfectionHeLa CellsAuranofinNuclear Receptor Co-Repressor 2Phorbol EstersCell Transformation, NeoplasticChromosomes, Human, Pair 11Dose-Response Relationship, DrugLeukemic InfiltrationMonocytesCholecalciferolInduction ChemotherapyCaspasesDrug Screening Assays, AntitumorLeukocyte CountSantoninGene RearrangementCell SurvivalTetrahydronaphthalenes
CajalLeukemiaCellsNucleusAcute promyeloLeukaemiaCajal BodiesUbiquitinNucleiNeuronalCellsNuclear structuresAnalysisFunctions
Cajal3
  • Cajal (Coiled) Bodies. (jrank.org)
  • By electron microscopy, Cajal bodies are seen as tangled balls of thread. (jrank.org)
  • More tightly coiled, smaller versions of Cajal bodies, gems are frequently seen interacting with Cajal bodies and are distinct structures. (jrank.org)
Leukemia1
  • Their normal pattern is altered in the nuclei of human acute promyelocytic leukemia. (jrank.org)
Cells2
  • No PML bodies were found to be associated with the NIIs, which were morphologically mildly altered from those seen in human neural cells. (wikipedia.org)
  • When cells are infected with herpes simplex virus type 1, adenovirus, or human cytomegalovirus, PML bodies are disrupted. (jrank.org)
Nucleus1
  • Besides the nucleolus, the nucleus contains a number of other non-membrane-delineated bodies. (thexplore.net)
Acute promyelo3
  • The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). (crossfirebeilstein.com)
  • Down syndrome with microgranular variant of acute promyelocytic leukemia in a child: a case report. (medscape.com)
  • We found PMLRARα interaction with Fas in acute promyelocytic leukemia (APL)-derived cells and APL primary cells, and PML-Fas complexes in normal tissues. (ashpublications.org)
Leukaemia2
  • 3. Promyelocytic leukaemia-immunoreactive neuronal intranuclear rodlets in the human brain. (nih.gov)
  • 14. Two populations of neuronal intranuclear inclusions in SCA7 differ in size and promyelocytic leukaemia protein content. (nih.gov)
Cajal Bodies1
  • Cajal bodies (CBs) are nuclear structures that are thought to have diverse functions, including small nuclear ribonucleoprotein (snRNP) biogenesis. (biologists.com)
Ubiquitin1
  • 11. Immunohistochemical analysis of Marinesco bodies, using antibodies against proteins implicated in the ubiquitin-proteasome system, autophagy and aggresome formation. (nih.gov)
Nuclei1
  • 6. Parallel enlargement of Marinesco bodies and nuclei and progressive deposition of p62 in pigmented neurons of the substantia nigra. (nih.gov)
Neuronal1
  • 7. PML nuclear bodies and neuronal intranuclear inclusion in polyglutamine diseases. (nih.gov)
Cells1
  • No PML bodies were found to be associated with the NIIs, which were morphologically mildly altered from those seen in human neural cells. (wikipedia.org)
Nuclear structures1
  • Small, punctate nuclear structures found in close proximity to COILED BODIES . (bvsalud.org)
Analysis1
  • PMID- 3504201 TI - Radio-frequency coils in implantable devices: misalignment analysis and design procedure. (nih.gov)
Functions2
  • This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. (crossfirebeilstein.com)
  • Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. (nih.gov)