Promoter Regions, GeneticBase SequenceDNA-Binding ProteinsGenes, p53Molecular Sequence DataGene Expression RegulationTranscription, GeneticTumor Suppressor Protein p53Transcriptional ActivationBinding SitesTransfectionMutationDNA MethylationCell LineRNA, MessengerPlasmidsGenes, ReporterNuclear ProteinsGenes, p16Sp1 Transcription FactorTrans-ActivatorsDNARepressor ProteinsProtein BindingCyclin-Dependent Kinase Inhibitor p16Regulatory Sequences, Nucleic AcidTumor Cells, CulturedCloning, MolecularCyclin-Dependent Kinase Inhibitor p21TATA BoxLuciferasesResponse ElementsGene Expression Regulation, BacterialTranscription FactorsTranscription Initiation SiteChloramphenicol O-AcetyltransferaseGene ExpressionDNA PrimersCyclin-Dependent Kinase Inhibitor p15Polymerase Chain ReactionOperonDNA FootprintingEnhancer Elements, GeneticGenes, Tumor SuppressorCell Line, TumorCpG IslandsElectrophoretic Mobility Shift AssayAmino Acid SequenceGenetic VectorsGene DeletionGene Expression Regulation, NeoplasticDNA-Directed RNA PolymerasesExonsEscherichia coliCells, CulturedChromatin ImmunoprecipitationRestriction MappingBacterial ProteinsHeLa CellsGene SilencingSequence Homology, Nucleic AcidTumor Suppressor ProteinsReverse Transcriptase Polymerase Chain ReactionGene Expression Regulation, EnzymologicRecombinant Fusion ProteinsSequence DeletionSequence Analysis, DNAGene Expression Regulation, ViralApoptosisDeoxyribonuclease IPolymorphism, Single-Stranded ConformationalCell NucleusDNA Mutational AnalysisGenes, Bacterialbeta-GalactosidaseConsensus Sequence5' Flanking RegionCyclin-Dependent Kinase Inhibitor p57AcetylationProto-Oncogene ProteinsCyclinsSignal TransductionDown-RegulationBlotting, WesternGenes, ViralGenes, RegulatorChromosomes, Human, Pair 9Mutagenesis, Site-DirectedLac OperonGenesChromatinSigma FactorHistonesCell Cycle ProteinsTransgenesDNA, BacterialCell CycleAllelesAdenoviridaeUp-Regulation