KeratinocytesDNA DamageCell ProliferationEpidermisCells, CulturedDNA RepairComet AssayUltraviolet RaysSkinApoptosisCell CycleSignal TransductionCell Cycle ProteinsCell DifferentiationCell DivisionCell LineCell Line, TumorDNA-Binding ProteinsAtaxia Telangiectasia Mutated ProteinsTumor Suppressor Protein p53Cell SurvivalRNA, MessengerProtein-Serine-Threonine KinasesPhosphorylationFibroblastsDNATumor Suppressor ProteinsKeratinsDeoxyguanosineGene Expression RegulationNuclear ProteinsBlotting, WesternImmunohistochemistryOxidative StressCheckpoint Kinase 2Mice, Inbred C57BLPsoriasisMutationWound HealingCell MovementRNA, Small InterferingTime FactorsMice, KnockoutGene ExpressionDNA Breaks, Double-StrandedGamma RaysReverse Transcriptase Polymerase Chain ReactionMolecular Sequence DataProliferating Cell Nuclear AntigenTumor Cells, CulturedTransfectionDose-Response Relationship, DrugFlow CytometryUp-RegulationCell Line, TransformedDown-RegulationMice, TransgenicDNA ReplicationTranscription FactorsSkin NeoplasmsHistonesBromodeoxyuridineKeratin-10Models, BiologicalG2 PhaseEpithelial CellsBase SequenceReactive Oxygen SpeciesCell AgingKeratin-14Dose-Response Relationship, RadiationCell Transformation, NeoplasticMutagensEnzyme ActivationS PhaseCell NucleusCyclin-Dependent Kinase Inhibitor p21Cell Cycle CheckpointsGenomic InstabilityMitosisRNA InterferenceTranscription, GeneticMethyl MethanesulfonateMelanocytesProtein BindingHydrogen PeroxideStem CellsHeLa CellsHair FollicleLymphocyte ActivationGene Expression Regulation, NeoplasticDermatitisEnzyme InhibitorsMice, Inbred BALB CSkin, ArtificialProtein KinasesIntracellular Signaling Peptides and ProteinsCell AdhesionPhenotypePoly(ADP-ribose) Polymerases