ApoptosisCell ProliferationApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsCell Line, TumorSignal TransductionCells, CulturedCell SurvivalDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinX-Linked Inhibitor of Apoptosis ProteinTumor Cells, CulturedCell CycleApoptosis Inducing FactorCell DivisionCASP8 and FADD-Like Apoptosis Regulating ProteinEnzyme ActivationTumor Suppressor Protein p53Caspase 9Caspase InhibitorsCell LineBlotting, WesternMitochondriaCaspase 8Flow CytometryFas Ligand ProteinCytochromes cbcl-X ProteinProto-Oncogene ProteinsAntineoplastic AgentsTransfectionRNA, MessengerRNA, Small InterferingAnnexin A5Down-RegulationPhosphorylationCell DifferentiationEnzyme InhibitorsMice, Inbred C57BLDose-Response Relationship, DrugCysteine Proteinase InhibitorsAmino Acid Chloromethyl KetonesReverse Transcriptase Polymerase Chain ReactionImmunohistochemistryUp-RegulationTime FactorsPoly(ADP-ribose) PolymerasesProto-Oncogene Proteins c-aktGene Expression Regulation, NeoplasticReactive Oxygen SpeciesMice, KnockoutJurkat CellsCell DeathGene Expression RegulationTumor Necrosis Factor-alphaHL-60 CellsTNF-Related Apoptosis-Inducing LigandEpithelial CellsMembrane GlycoproteinsCaspase 7Gene ExpressionNF-kappa BMembrane Potential, MitochondrialRNA InterferenceProtein-Serine-Threonine KinasesFibroblastsT-LymphocytesGenes, bcl-2NecrosisMice, NudeMice, TransgenicNeoplasm ProteinsDNA DamageDNA-Binding ProteinsLymphocyte ActivationMitogen-Activated Protein KinasesCarrier ProteinsDrug Synergismbcl-2 Homologous Antagonist-Killer ProteinTranscription FactorsCell MovementMyeloid Cell Leukemia Sequence 1 ProteinCytochrome c GroupRats, Sprague-DawleyModels, BiologicalCyclin-Dependent Kinase Inhibitor p21Membrane ProteinsMolecular Sequence DataHeLa CellsMutationAntineoplastic Agents, PhytogenicMice, Inbred BALB CBH3 Interacting Domain Death Agonist ProteinStaurosporineBromodeoxyuridinePhosphatidylinositol 3-Kinases