• The SHFS participants provided clinical examinations matching earlier phases, as well as DNA samples for genome-wide linkage analysis of cardiovascular disease biomarkers. (wikipedia.org)
  • Using large datasets, we are investigating the role of high-sensitivity troponin I (and other cardiovascular biomarkers) as a measure of outcome in patients with CKD and those undergoing kidney transplantation. (ed.ac.uk)
  • 3. Identify novel biomarkers for food and nutrient intake related to dietary patterns and cardiovascular health. (usda.gov)
  • 3.1 - Effect of a comprehensive 12 month approach to family weight management on biomarkers of dietary intake and cardiometabolic risk factors in child-mothers/female guardian pairs. (usda.gov)
  • 3.2 - Novel nutrient biomarkers to predict risk of heart failure. (usda.gov)
  • In addition, the CNL will identify and adjudicate novel biomarkers for food and nutrient intake and merge them with established biomarkers thereof, and assess potential relationships with family-wide CVD risk and weight management, and heart failure risk. (usda.gov)
  • We are currently exploring the role of specific microRNAs as biomarkers of disease activity in ANCA vasculitis. (ed.ac.uk)
  • Objectives: The aim of the work was to find biomarkers identifying patients at high risk of adverse clinical outcomes after TAVI and SAVR in addition to currently used predictive model (EuroSCORE). (muni.cz)
  • RNA analysis of blood from patients with angiographically confirmed coronary artery disease demonstrates how RNA biomarkers may help confirm heart disease. (labpulse.com)
  • In this paper we investigate the use of the joint model framework with a random intercept association structure as an approach to adjust for measurement error, inherent in biomarkers such as SBP. (biomedcentral.com)
  • Considering the limitation of studies investigating the relationship between T. gondii and cardiovascular biomarkers, this study was focused on assessing the association of T. gondii to nine cardiovascular biomarkers. (mdpi.com)
  • 4 Further, envision a society in which biomarkers for suicide and predictive analytics are further refined and scaled to national level so that every patient in primary care has the benefit of mental health screening and suicide preventive interventions, as they do for other leading causes of death (eg, cardiovascular disease, cancer, infectious diseases). (psychiatrictimes.com)
  • We will review several projects based on the use of panels of biomarkers for a better understanding of risk of disease and prognosis. (lu.se)
  • Environmental factors, including air and noise pollution, and the built environment, are typically associated with cardiovascular and metabolic non-communicable diseases (NCDs), e.g. obesity, type 2 diabetes, heart diseases and atherosclerosis. (europa.eu)
  • Evidence-based life-course causal models will estimate how clinical and policy interventions may sustainably affect the health and economic burden of NCDs. (europa.eu)
  • LONGITOOLS will also allow researchers and policy makers to generate new knowledge - identifying the likely causal (direct and indirect) mechanisms through which exposures to man-made environmental factors affect the risk of NCDs. (europa.eu)
  • This review describes, analyzes and compares the effects of different types of diets in reducing the onset of typical Western countries non-communicable diseases (NCDs) (cardiovascular diseases, tumors, chronic respiratory diseases, diabetes, etc.), thus increasing the average lifespan. (iospress.com)
  • At the beginning of this century, the World Health Organization (WHO) found that the so-called non-communicable diseases (NCDs), also known as chronic diseases, are responsible for the death of forty million people every year, equivalent to 70% of all deaths globally. (iospress.com)
  • Cardiovascular diseases (CVDs) account for most NCDs deaths (17.7 million people annually), followed by cancers (8.8 million), respiratory diseases (3.9 million) and diabetes (1.6 million) [ 1 ]. (iospress.com)
  • Among the individuals aged 60 and over, NCDs account for more than 87% of the disease burden, with an higher age-related occurrence of chronic diseases, disabilities, morbidity and mortality [ 4-7 ]. (iospress.com)
  • The overall aim of this study was to determine the feasibility of recommending a screening process for non-communicable diseases (NCDs) and their risk factors, as a national and regional model. (uwi.edu)
  • 2030. Modelled figures suggest that cancer incidence an epidemiological transition from communicable and deaths will almost double, with 555 000 new cases of diseases to NCDs such as cardiovascular diseases, cancer in 2012, compared to a prediction of 961 000 new diabetes and cancer ( 3 ). (who.int)
  • It repeated and expanded the clinical examination from Phase I, in order to monitor changes in risk factor prevalence over time and expand incidence rates beyond CVD to include hypertension and diabetes. (wikipedia.org)
  • Chronic kidney disease (CKD) is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. (news-medical.net)
  • Most of this is clinical research that focuses on nutritional and pharmacologic interventions for the prevention and early treatment of type 2 diabetes and metabolic dysfunction associated with steatotic liver disease (MASLD). (tu.edu)
  • Our work includes studying the role of fructose metabolism and meal composition in CVD, diabetes, and other metabolic diseases. (tu.edu)
  • For a separate project, she looked at how achieving treatment targets for diabetes patients impact health outcomes and healthcare costs. (ox.ac.uk)
  • She is currently pursuing her DPhil to work on developing a framework to model lifetime outcomes for diabetes patients using data from the ASCEND trial. (ox.ac.uk)
  • Resolution WHA53.17 recognized the enormous human suffering caused by noncommunicable diseases such as cardiovascular diseases, cancer, diabetes and chronic respiratory diseases, and the threat they pose to the economies of many Member States. (who.int)
  • About 80% of premature heart disease and stroke, 80% of type 2 diabetes and 40% of cancers are preventable. (who.int)
  • Multimedia Diabetes Type 2 Risk Text Calculator (Text & Images). (martindalecenter.com)
  • Depression, cardiovascular diseases and diabetes are among the major non-communicable diseases, leading to significant disability and mortality worldwide. (plos.org)
  • The World Health Organisation has identified mental disorders, including depression, cardiovascular diseases and diabetes among the six major non-communicable diseases [ 1 ]. (plos.org)
  • This thesis is focused on cardiovascular disease (CVD) and type 2 diabetes mellitus (T2D), two concomitant conditions that appear with growing concern. (lu.se)
  • Annual costs from the health system perspective were estimated using the Excel-based HEARTS costing tool under two intervention scenarios - hypertension-only control and a CVD risk management program, which addresses diabetes and hypercholesterolemia in addition to hypertension. (cdc.gov)
  • cardiovascular disease, diabetes, COPD and cancer. (who.int)
  • More people contract cardiovascular make the path to the checkout something other than a disease, diabetes, chronic lung disease and cancer. (who.int)
  • The strategy shall also cardiovascular disease, diabetes, chronic lung disease help to ensure that all those who are affected suffer as and cancer before the age of 75. (who.int)
  • Discussed accomplishments of Million Hearts, state how evidence-based strategies can help identify and address the needs of those at greatest risk for heart attack and stroke, and discuss the use of standardized treatment approaches to improve outcomes for patients at risk for heart attack and stroke. (cdc.gov)
  • To model the financial and health outcomes impact of intensive statin therapy compared with usual care in a high-risk working-age population (actively employed, commercially insured health plan members and their adult dependents). (ahdbonline.com)
  • It's the ability to model outcomes that's new here, says American Heart Association president Dr. Mark Creager , a cardiovascular disease expert. (npr.org)
  • Long work hours and adverse health outcomes: defining a health risk-based threshold for work hour exposure. (cdc.gov)
  • These results indicate that LWH could be recognized as a potential risk indicator for poor SRGH, CVD, and cancer, thereby contributing to the growing body of evidence regarding LWH and adverse health outcomes. (cdc.gov)
  • Our goals are to identify cardiovascular risk early in patients with CKD, to investigate novel therapies that might reduce this risk and so improve longer-term patient outcomes. (ed.ac.uk)
  • In population-based studies utilising high-fidelity linked healthcare data unique to Scotland, we are investigating temporal trends in the incidence and outcomes of cardiovascular disease, including rates of secondary prevention prescribing, in patients with kidney failure. (ed.ac.uk)
  • The CNL will determine the relationship between food preferences, consumption patterns and dietary acculturation, and cardiovascular health using population-based datasets by assessing the impact of acculturation status on dietary patterns and health outcomes. (usda.gov)
  • For a wide range of complex diseases, deriving intelligence from nationwide, multisource, linked health relevant data has the potential to yield crucial insights that accelerate and enhance opportunities for innovation in disease detection, diagnosis, treatment, improved care, better outcomes and more rational health policy. (findaphd.com)
  • Conclusion: We identified malondialdehyde, a marker of oxidative stress, as the most promising predictor of adverse outcomes during the 30-day and 1-year follow-up in high-risk patients with symptomatic, severe aortic stenosis treated with TAVI. (muni.cz)
  • According to Albert, people of color face a greater risk of poor health outcomes due to chronic stress, depression and anxiety linked to psychosocial stressors, particularly those related to social and economic inequality, discrimination, systemic racism and other societal factors. (healthliving101.com)
  • Timely identification of these patients through risk stratification and prediction of outcomes post-revascularization remain important challenges. (manchester.ac.uk)
  • Additionally, by sharing these experiences more freely with trusted others, our sense of connectedness can lead to better health outcomes in many arenas including suicide risk reduction. (psychiatrictimes.com)
  • The Spinal Cord Injury Rehabilitation (SCIRehab) project, a 5-year project led by the Rocky Mountain Regional Spinal Injury System (RMRSIS) at Craig Hospital, used practice-based evidence (PBE) research to identify the rehabilitation interventions most strongly associated with positive outcomes. (medscape.com)
  • The aim of the SCIRehab project was to provide detailed information on treatments delivered by rehabilitation disciplines and to contribute to outcomes-based guidelines for clinical decision-making. (medscape.com)
  • The SCIRehab project included 1376 patients with acute SCIs, with outcome data being abstracted from medical records (clinical outcomes data) at six SCI rehabilitation facilities and obtained from patient interviews at 6 and 12 months after injury. (medscape.com)
  • Our projects were based upon the Västerbotten Health Survey (VHU) and the Malmö Diet and Cancer (MDCS) studies, which included extensive data on lifestyle, biological intermediates, and clinical outcomes. (lu.se)
  • Evans M, Carrero JJ, Bellocco R, Barany P, Qureshi AR, Seeberger A, Jacobson SH, Hylander-Rössner B, Rotnitzky A, Sjölander A. Initiation of erythropoiesis-stimulating agents and outcomes: a nationwide observational cohort study in anaemic chronic kidney disease patients. (janusinfo.se)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • Conclusions Our model can be used to estimate the impact of primary prevention interventions on life expectancy and can assess the impact of interventions on inequalities. (bmj.com)
  • I'm Loretta Jackson-Brown and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Center for Disease Control and Prevention. (cdc.gov)
  • APhA is a founding member of the National Hypertension Control Roundtable and has long championed the pharmacist's role in controlling hypertension by engaging in the Million Hearts initiative and collaboration with the National Forum for Heart Disease and Stroke Prevention . (pharmacist.com)
  • The Community Preventive Services Task Force (CPSTF) recommends tailored pharmacy-based adherence interventions for cardiovascular disease prevention. (pharmacist.com)
  • Whether different modalities of weight management impede LDN/MDSC accumulation, and therefore, mitigate the malignancy risk in obesity, could foster a new treatment paradigm in cancer prevention. (pbrc.edu)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Because dietary factors 'contribute substantially to the burden of preventable illness and premature death in the United States,' the national health promotion and disease prevention objectives encourage schools to provide nutrition education from preschool through 12th grade (1). (cdc.gov)
  • Resolution WHA53.17 urged Member States to develop, inter alia, a national policy framework, establish programmes, share their experiences and build capacity at regional, national and community levels for the development, implementation and evaluation of programmes for the prevention and control of noncommunicable diseases. (who.int)
  • Nevertheless, the proportion of the health budget spent, in general, on prevention and control of chronic noncommunicable diseases remains very small. (who.int)
  • WHO has continued to give priority to the integrated, step-by-step approach to the surveillance, prevention and control of chronic diseases, with special emphasis on low- and middle-income countries. (who.int)
  • To address cardiovascular disease risk factors among Hispanics, a community model of prevention requires a comprehensive approach to community engagement. (cdc.gov)
  • Community health promotion and disease prevention models are needed to compensate for the large number of uninsured, underinsured, and disadvantaged people living in these communities. (cdc.gov)
  • Moving from a clinical model of care to a community model of prevention requires a comprehensive approach to community engagement (2-5). (cdc.gov)
  • Page 2 of 9 year initiative introducing community-based participatory research (CBPR) to engage academia and communities in setting up programs with an ecological approach to health promotion and disease prevention. (cdc.gov)
  • The environmental restructuring is designed to promote community use of existing physical activity and nutrition facilities and to integrate promotores into public-sector settings such as public parks, to address cardiovascular health promotion and CVD prevention. (cdc.gov)
  • and in which the RAISE early prevention/intervention model is applied to prodromal or burgeoning mental illness with treatment and self/family strategies as part of recovery. (psychiatrictimes.com)
  • OBJECTIVE: To estimate the costs of implementing the HEARTS program for hypertension control and cardiovascular disease (CVD) prevention in the primary care setting in Ethiopia for adult primary care users in the catchment area of five examined facilities. (cdc.gov)
  • In the absence of curative treatment, the primary prevention of dementia through risk factor reduction, such as blood pressure lowering, becomes a public health priority. (medscape.com)
  • Last, but by no means least: the patient organisations more and capture disease at an early stage - where are important players when it comes both to prevention people live. (who.int)
  • We have chosen to create a common strategy for time, the efforts that are specific to each disease prevention, diagnosis, treatment and rehabilitation for shall be maintained. (who.int)
  • Although lifestyle interventions at an earlier age could be advantageous, there would be small gains under the age of 65, and medical interventions carry risks as soon as they are initiated. (bmj.com)
  • 1 National policies now support targeting of interventions to reduce risk of cardiovascular disease among high risk patients. (bmj.com)
  • Some argue that younger patients with an adverse risk profile may have more to gain during their lifetime if interventions are started at a younger age rather than waiting until they cross the 20% threshold. (bmj.com)
  • Objectives A policy model is a model that can evaluate the effectiveness and cost-effectiveness of interventions and inform policy decisions. (bmj.com)
  • Simulations and models are used to provide insights into infectious disease trends, quantify likely benefits of public health interventions, and support risk assessment for emerging infectious diseases. (edu.au)
  • Since high CHOL and TG are modifiable CVD risk factors, increased education and lifestyle modification interventions are warranted to prevent the development of high CHOL or TG among PWH. (nih.gov)
  • Aim 2 is a new set of CVD health policy models that estimate the impact within each state of interventions shown to improve the delivery of pharmacotherapies that lower blood pressure and LDL-cholesterol. (washington.edu)
  • Aim 3 is a new set of CVD health policy models that estimate the impact of behavioral interventions shown to reduce CVD risk factors. (washington.edu)
  • In some Member States, interventions have been successfully implemented and are models for expansion. (who.int)
  • 50 mg/L). Upper reference lipoprotein(a) levels of 500 mg/L or 300 mg/L both appear appropriate for identifying those who may benefit from intensive risk reduction interventions. (labpulse.com)
  • The Strategically Focused Research Network (SFRN) on Biologic Pathways of Chronic Psychosocial Stressors on Cardiovascular Health of the American Heart Association, the world's leading voluntary organization dedicated to a world of longer, healthier lives, will focus on learning more about how the body responds to chronic stress, as well as how certain interventions may help reduce health risks. (healthliving101.com)
  • And we need to identify specific stress interventions at population levels and determine how those interventions relate to underlying molecular mechanisms," said Albert, who is the Walter A Haas-Lucie Stern Endowed Chair and professor of medicine, director of the CeNter for the StUdy of AdveRsiTy and CardiovascUlaR DiseasE (NURTURE Center) and associate dean of admissions at the University of California, San Francisco. (healthliving101.com)
  • This prevents a full understanding of causal pathways towards the shared risk of these diseases and the development of coordinated preventive and therapeutic interventions. (plos.org)
  • 6 7 Worryingly, three recent reanalyses of randomised trials in women have indicated a higher risk of both ischemic heart disease and stroke with calcium supplements, 8 9 10 a pattern not observed in a reanalysis of another randomised trial. (bmj.com)
  • Estimates will be produced separately by sex and 5-year age groups, for four collectively exhaustive race/ethnicity categories for CVD overall, and separately for ischemic heart disease, heart failure, stroke, peripheral vascular disease, aortic aneurysm, and chronic kidney disease. (washington.edu)
  • Cardiovascular diseases (CVD), principally ischemic heart disease (IHD) and stroke, are the leading causes of death (18. (cdc.gov)
  • Warmer temperatures are also a public health problem in and of themselves, aiding the spread of infectious diseases and increasing rates of malnutrition. (popsci.com)
  • Infectious diseases pose a local and global challenge, with substantial human and economic costs. (edu.au)
  • PRISM² will extend existing national modelling capacity and cross-sectoral partnerships to inform infectious disease preparedness, control and response in Australia and our region. (edu.au)
  • 10 years, while deaths from infectious diseases, maternal and perinatal conditions and nutritional deficiencies combined are expected to decline. (who.int)
  • Most research coming from the Global Public Health team is based on population-based epidemiological studies, analysis of register data, surveillance and modelling based on the epidemiological data, clinical and molecular epidemiology studies, health promotion studies, health system research, and development studies. (gu.se)
  • Data-driven machine learning model, ATOMIC, is accelerating clinical trials, bringing medicines to patients more quickly. (amgen.com)
  • The ATOMIC project team has been working with Amgen's Global Development Operations (GDO), Center for Design & Analysis (CfDA), Center for Observational Research (CfOR) and Representation in Clinical Research (RISE) teams on ways to increase the diversity and improve the representation of clinical trial investigator and participant populations. (amgen.com)
  • Reductions in cardiovascular and stroke events reported in clinical trials with aggressive statin therapy were applied to these cohorts. (ahdbonline.com)
  • Aggressive low-density lipoprotein cholesterol-lowering therapy for working-age people at high risk for cardiovascular events and with a history of heart disease appears to have a significant potential to reduce the rate of clinical events and is cost-neutral for payers. (ahdbonline.com)
  • Phase I of the study was conducted among adult tribal members from 1984 to 1988 and consisted of three parts: a mortality survey to estimate cardiovascular disease mortality rates, a morbidity survey to estimate incidence of myocardial infarction and stroke, and a comprehensive clinical examination of 4,549 tribal members to estimate the prevalence of cardiovascular disease and its associations with risk factors. (wikipedia.org)
  • The novel coronavirus disease 2019 (COVID-19) shows a wide spectrum of clinical presentations, severity, and fatality rates. (mdpi.com)
  • We perform pre-clinical and experimental medicine studies as well as investigating cardiovascular risk at a population level. (ed.ac.uk)
  • We also complete clinical pharmacologic trials on diabetic kidney disease. (tu.edu)
  • Perform large scale profiling HILIC metabolite analysis related to nitric oxide biology, oxidative stress and inflammation in plasma before and after 12 weeks of oral curcumin (2000 mg/d) or placebo (double-blind, randomized) in men and women aged 45-79 years who are free from clinical cardiovascular disease. (sdsc.edu)
  • She has worked as a regulatory project manager, and also has experience of Regulatory Writing, including compiling briefing documents for Regulatory Agency meetings, as well as writing Module 2 clinical summaries, and Module 1 documents for MAAs and NDAs. (xtalks.com)
  • Our clinical studies are supported by relevant pre-clinical models where we are investigating the roles of these microRNAs as mediators of renal and extra-renal disease. (ed.ac.uk)
  • The addition of MDA to a currently used clinical model (EuroSCORE) significantly improved prediction of a combined safety endpoint at 30 days and a combined endpoint (0-365 days) by the net reclassification improvement (NRI) and the integrated discrimination improvement (IDI) (p,0.05). (muni.cz)
  • He was tenured Professor of Cardiovascular Imaging&Dynamics at the Medical Faculty in Leuven (1998-04), supervised clinical research at St. George's Hospital in London (2005-6) and was resident Visiting Professor at the University of Zagreb (2007), Croatia. (icrea.cat)
  • These results may be useful when selecting methods and instruments for clinical follow-up models. (lu.se)
  • Patients identified as high risk with the lifetime risk approach were more likely to be younger, male, from ethnic minority groups, and have a positive family history of premature coronary heart disease than those identified with the 10 year QRISK2 score. (bmj.com)
  • In Scotland, although mortality rates have declined steadily for decades (eg, coronary heart disease (CHD) mortality rates for men were 72% lower in 2009 than in 1950), in 2009, Scottish CHD mortality rates for men and women were 39% and 64% higher, respectively, than the average for Western Europe. (bmj.com)
  • The Finnish Cultural Foundation has awarded significant grants to 6 projects studying, among other things, coronary artery disease and heart insufficiency. (skr.fi)
  • The most common cardiovascular diseases are coronary artery disease, heart insufficiency, and cerebrovascular disease. (skr.fi)
  • Professor Juhani Knuuti and the KOVERI research project (Turku PET Centre) received €264,500 for research on imaging changes in other organs related to coronary artery disease. (skr.fi)
  • The research is producing unique information on the interaction between the heart and other organs and on the changes caused by coronary artery disease in the blood circulation of other organs. (skr.fi)
  • The target population consists of working-age people who are considered high-risk for cardiovascular disease events because of a history of coronary heart disease. (ahdbonline.com)
  • Using Framingham risk scoring system, the probability of myocardial infarction or stroke events was calculated for a representative sample population, ages 35 to 69 years, of people at high risk for cardiovascular disease, with a history of coronary heart disease. (ahdbonline.com)
  • The high-risk cohort (those with coronary heart disease) comprises 4% of the 35- to 69-year-old commercially insured population but generates 22% of the risk for coronary heart disease and stroke. (ahdbonline.com)
  • 1 Hypercholesterolemia, particularly elevated lowdensity lipoprotein cholesterol (LDL-C), is strongly associated with an increased risk of CVD, including coronary heart disease (CHD) events (ie, myocardial infarction [MI], angina, coronary revascularization) and stroke. (ahdbonline.com)
  • It is unknown, however, whether mild-to-moderate kidney dysfunction is causally related to coronary heart disease (CHD) and stroke. (easp.es)
  • After adjusting for age and sex no significant association was found between coronary risk factors and subjective job strain. (bmj.com)
  • and may prevent long-term health problems, such as coronary heart disease, cancer, and stroke. (cdc.gov)
  • 1.5 - Relationship of dietary fat type to HDL functionality, composition and concentration, and association with coronary heart disease. (usda.gov)
  • Increased blood levels of lipoprotein(a), a bad cholesterol variant, are a risk factor for recurrent coronary heart disease (CHD) in people over 60. (labpulse.com)
  • The risks include strokes, heart disease, chronic obstructive pulmonary disease, lung cancer and cardiovascular and other respiratory diseases. (banktrack.org)
  • During recent years, results from a growing number of studies indicate that air pollution influences not only cardio-respiratory health and cancer but may also increase risk for cognitive decline and risk for development of Alzheimer's disease (AD) and other dementias [ 7 ]. (biomedcentral.com)
  • Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. (bmj.com)
  • Of the 10% of patients in the validation cohort classified at highest risk with either the lifetime risk model or the 10 year risk model, only 18 385(14.5%) were at high risk on both measures. (bmj.com)
  • Design A state transition model was developed using the Scottish Heart Health Extended Cohort (SHHEC) linked to Scottish morbidity and death records. (bmj.com)
  • Our analysis models the cost impact of aggressive statin therapy for a commercially insured cohort of members at high risk for secondary events from CVD as a result of a history of CHD. (ahdbonline.com)
  • The Strong Heart Study is an ongoing cohort study of cardiovascular disease (CVD) and its risk factors among American Indian men and women. (wikipedia.org)
  • Phase V and VI continued the mortality and morbidity surveillance of the original SHS cohort and of the SHFS participants to better understand cardiovascular disease, cancer, liver disease, and inflammation. (wikipedia.org)
  • The European Society of Cardiology initiated the development of a new risk estimation system (SCORE2) using data from 45 cohort studies (N= 677,684) covering a wide geographic spread of countries at different levels of cardiovascular risks. (heartscore.org)
  • Furthermore, a new competing risk-adjusted model was developed for adults aged 70 years and older: SCORE2-OP. Models for SCORE2-OP were derived in individuals aged over 65 without pre-existing atherosclerotic CVD from the Cohort of Norway (28,503 individuals, 10,089 CVD events) and were recalibrated using region-specific estimated CVD incidence rates and risk factor distributions. (heartscore.org)
  • The researchers studied nearly 5,000 proteins in 2,667 participants with CKD from the Chronic Renal Insufficiency Cohort (CRIC) and the Atherosclerosis Risk in Communities (ARIC) cohort. (news-medical.net)
  • This new model was found to be more accurate in identifying those at risk of future cardiovascular disease, as compared to both the 2013 ACC/AHA Pooled Cohort Equation (PCE)-;which provides a set of guidelines for best practices in measuring cardiovascular risk-;and a modified PCE that included estimated glomerular filtrate rate (eGFR). (news-medical.net)
  • This prospective cohort study aimed to investigate the association between fruit and vegetable intake and the risk of new-onset hypertension. (bvsalud.org)
  • The project takes advantage of human longitudinal birth cohort data, animal studies and cellular models to test the hypothesis of shared mechanisms and molecular pathways by which ELS shapes an individual's physical and mental health in adulthood. (plos.org)
  • Scholars@Duke publication: In middle-aged adults, Astro-CHARM was better than a standard risk factor model for predicting 10-year ASCVD risk. (duke.edu)
  • Main outcome measures Primary outcome measures, identified from registry data, were time to death from all causes (n=11 944) and cause specific cardiovascular disease (n=3862), ischaemic heart disease (n=1932), and stroke (n=1100). (bmj.com)
  • Compared with intakes between 600 and 1000 mg/day, intakes above 1400 mg/day were associated with higher death rates from all causes (hazard ratio 1.40, 95% confidence interval 1.17 to 1.67), cardiovascular disease (1 49, 1.09 to 2.02), and ischaemic heart disease (2.14, 1.48 to 3.09) but not from stroke (0.73, 0.33 to 1.65). (bmj.com)
  • Conclusion High intakes of calcium in women are associated with higher death rates from all causes and cardiovascular disease but not from stroke. (bmj.com)
  • The HeartScore® web-based program estimates 10-year risk of a myocardial infarction, stroke or cardiovascular death, based on age, sex, smoking habits, systolic blood pressure and non-HDL cholesterol. (heartscore.org)
  • Now computer models suggest slashing its price by about a third could result in dramatically lower death rates from heart disease and stroke. (npr.org)
  • Now computer models suggest that making that produce more affordable may actually translate into lower death rates from heart disease and stroke. (npr.org)
  • Those specific proteins were determined to best help indicate a patient's risk level of heart attack, heart failure, stroke, or even cardiovascular death in those with CKD. (news-medical.net)
  • By directly modelling the longitudinal component we reduce bias in the hazard ratio for the effect of baseline SBP on the time-to-stroke, showing the large potential to improve on previous prognostic models which use only observed baseline biomarker values. (biomedcentral.com)
  • A joint model of longitudinal and survival data allows us to investigate the relationship between a repeatedly measured biomarker, subject to measurement error, such as SBP, and the time to an event of interest, such as time to non-fatal stroke. (biomedcentral.com)
  • Hot temperatures contribute to increased emergency-room visits and hospital admissions for cardiovascular disease, and can cause heat stroke and other life-threatening conditions. (grist.org)
  • These rodent model studies - using relevant exposure scenarios mimicking mouth-breathing exposures/pollutant levels in that critical period - will help us better understand the bases for the still-increasing incidence of CV anomalies reported in first responders. (cdc.gov)
  • Cancer and cardiovascular diseases (CVD) are the two commonest causes of morbidity and mortality in the UK and globally, with incidence, morbidity and mortality increasing over the last several decades as the world's population has aged. (findaphd.com)
  • All participants had CKD and no history of cardiovascular disease at study baseline. (news-medical.net)
  • The reliable identification of such high-risk individuals with no prior history of cardiovascular disease will undoubtedly be of great interest to patients and their providers for preventative care measures. (news-medical.net)
  • Sleep disruption is one of the most common symptoms during the menopausal transition and post menopause, but whether it exacerbates the detrimental impact of menopause on cardiovascular and metabolic function is not known. (pbrc.edu)
  • The goal of this project is to identify key metabolic pathways that change with oral curcumin supplementation and to relate those changes with improvements in vascular function in MA/O adults with initial endothelial dysfunction. (sdsc.edu)
  • The study will research in detail how ELS converts into biological signals embedded simultaneously or sequentially in the brain, the cardiovascular and metabolic systems. (plos.org)
  • 1.1 - Relative effects of palmitate (16:0), stearate (18:0) and oleate (18:1) on cardiometabolic risk factors, fatty acid kinetics and lipoprotein-mediated in vitro endothelial cell inflammatory response. (usda.gov)
  • 1.2 - Relative effects of simple, refined and unrefined carbohydrate on cardiometabolic risk factors, macrophage cholesterol homeostasis, subcutaneous adipose tissue macrophage infiltration/inflammatory gene expression, and intestinal microbiome. (usda.gov)
  • LAB NAME: Cardiovascular Nutrition In the next 5 years the Cardiovascular Nutrition Laboratory (CNL) will investigate the effects of diets differing in fat type and carbohydrate type on cardiometabolic risk factors, fatty acid metabolism, response to lipid modifying therapy, and gene-nutrient interactions using human, animal and in vitro models. (usda.gov)
  • Diets of food-insecure adults may be of low quality ( 12 ), which in turn could affect cardiometabolic risk factors for cardiovascular disease. (cdc.gov)
  • Using mouse models of ischaemia-reperfusion injury, we are investigating the cardiovascular and renal sequelae of AKI and examining new experimental medicine strategies to reduce the risks of developing these. (ed.ac.uk)
  • Now in its seventh phase, the extensive research has led to many important findings about heart disease and unique risk factors in native populations. (wikipedia.org)
  • The pilot SHFS expanded into a fullblown SHFS conducted in Phase IV to investigate the heritability of CVD and its risk factors and perform linkage analysis to localize genes that contribute to CVD risk. (wikipedia.org)
  • Evaluates the impact of pharmacists, working collaboratively with patients, on blood pressure control, lifestyle goal setting, adherence to antihypertensive therapy, patient knowledge and satisfaction, and modification of cardiovascular risk factors. (pharmacist.com)
  • Job strain and cardiovascular risk factors: a cross sectional study of employed Danish men and women. (bmj.com)
  • This study aimed to determine the prevalence and risk factors associated with high CHOL or TG among PWH in Texas. (nih.gov)
  • Using observed past trends in CVD and major modifiable causal risk factors, we will project health loss due to CVD, including disability-adjusted life years (DALYs), through 2040 for each U.S. state. (washington.edu)
  • We are interested in risk factors for Long QT syndrome. (tu.edu)
  • The goal of these studies is to determine if imbalances in extracellular electrolytes such as potassium, calcium, and magnesium can impact the cardiac potassium channel HERG, and thus could be risk factors for Long QT. (tu.edu)
  • The common major risk factors for chronic diseases are the same for men and women in all regions: unhealthy diet, physical inactivity, and tobacco and alcohol use. (who.int)
  • The objectives of our intervention were to reduce cardiovascular disease risk factors in Hispanics living in 2 low-income areas of El Paso, Texas, and to engage the community in a physical activity and nutrition intervention. (cdc.gov)
  • The pilot test resulted in more awareness of CVD risk factors among Hispanics, greater confidence in the control of these factors, and improved dietary habits (4,6) among trial participants. (cdc.gov)
  • The objectives of phase 2 are 1) to reduce CVD risk factors among Hispanics and 2) to engage the community in an environmental restructuring initiative that focuses on nutrition and exercise. (cdc.gov)
  • WHO also piloted an NCD emergency kit in 12 PHC centres in northwest Syria and trained almost 200 health workers on risk factors for chronic diseases and managing patients with thalassaemia. (who.int)
  • The objective of this study was to examine the associations between food security status and cardiovascular disease risk factors and predicted 10-year risk in a national sample of US adults. (cdc.gov)
  • Little is known about the associations between food security and predicted cardiovascular disease risk, but some research has addressed associations between food security and several cardiovascular disease risk factors. (cdc.gov)
  • Therefore, the objective of this study was to examine the cross-sectional associations between cardiovascular disease risk factors, cardiovascular disease risk, and food security among US adults. (cdc.gov)
  • Stressful early-life events are among the primary factors associated with the development of mental and physical diseases. (plos.org)
  • Life-course models will integrate the role of modifying factors as sex, socioeconomics, and lifestyle with the goal to better identify groups at risk as well as inform promising strategies to reverse the possible mechanisms and/or reduce the impact of ELS on multi-morbidity development in high-risk individuals. (plos.org)
  • Two case-control studies examining risk factors for MRSA have found a significant association between fluoroquinolone exposure and MRSA isolation or infection ( 11 , 12 ). (cdc.gov)
  • Traditional cardiovascular risk factors together with baseline renal function and proteinuria are the most important determinants of adverse events in ARVD thus advocating the use of multi-targeted medical therapy and aggressive risk factor control in all patients with ARVD. (manchester.ac.uk)
  • The full continuum of mental health spans a wide range from joy to terrible anguish, and ambivalence between hope and hopelessness (and many other risk factors for suicide) is fairly common human experiences. (psychiatrictimes.com)
  • In Paper II, we implemented a machine learning-based model to identify individuals with variable susceptibility to lifestyle risk factors for T2D and CVD. (lu.se)
  • Neurologists did a variety of tests and assessments including collecting data on the patient's medical and psychiatric history and risk factors for dementia, as well as neurologic assessment using the Mini-Mental State Examination, the Functional Activities Questionnaire, and the Quick Dementia Rating System. (medscape.com)
  • Results: Among the long-term surviving participants (N = 457), serum NFL (n = 384) was associated to all outcome instruments, also when controlling for demographic and cardiovascular risk factors. (lu.se)
  • In addition we will address important areas of modern epidemiology such as the influence of early life factors on adult health and disease, but also the importance of the gene-diet-microbiota interaction for body function and health. (lu.se)
  • Adjunct professor Katariina Öörni and a research group at the Wihuri Research Institute received €180,000 for research on the reasons for the qualitative characteristics of lipoproteins and research on their effects on the development of cardiovascular diseases. (skr.fi)
  • Chronic stress is recognized as an independent risk factor for the development of cardiovascular disease, and it is known to negatively impact the overall health of people living with heart disease. (healthliving101.com)
  • WHO should play in promoting global action against noncommunicable diseases. (who.int)
  • The global epidemic of chronic noncommunicable diseases continues to grow. (who.int)
  • WHO's strategic directions and priorities as set out in the Programme budget 2006-2007 provide strong support for responding to the increasing burden of chronic noncommunicable diseases. (who.int)
  • Football teams can make sure that the noncommunicable national health problems and hungry little players taking part in organised events lifestyle diseases. (who.int)
  • Projections and policy models for CVD are a necessary step in reducing U.S. health disparities. (washington.edu)
  • Subjects Patients aged 30-84 years who were free of cardiovascular disease and not taking statins between 1 January 1994 and 30 April 2010: 2 343 759 in the derivation dataset, and 1 267 159 in the validation dataset. (bmj.com)
  • Results Across all the 1 267 159 patients in the validation dataset, the 50th, 75th, 90th, and 95th centile values for lifetime risk were 31%, 39%, 50%, and 57% respectively. (bmj.com)
  • Conclusions Compared with using a 10 year QRISK2 score, a lifetime risk score will tend to identify patients for intervention at a younger age. (bmj.com)
  • Applying this 20% risk threshold for intervention may not identify younger patients who, because of their age, have a low absolute 10 year risk but who have a high relative risk compared with their peers. (bmj.com)
  • By examining RWD, the ATOMIC project team and CfOR were also able to identify trial sites likely to be found near clusters of patients with high Lipoprotein(a), or Lp(a) levels. (amgen.com)
  • Using this newly developed model, we compare the CVD event and cost burden under conventional current therapy to represent the results of intensive statin therapy, which is the current standard of care for high-risk patients. (ahdbonline.com)
  • Risk information should be carefully adapted to the resources of individual patients. (heartscore.org)
  • The reason older patients and males show increased risk of severe disease and death remains uncertain. (mdpi.com)
  • Although current treatments have improved the short-term prognosis of AAV, these patients remain at a significantly increased risk of cardiovascular disease. (ed.ac.uk)
  • We are examining if short- and long-term ET receptor blockade will reduce cardiovascular risk in optimally managed patients with AAV. (ed.ac.uk)
  • Despite the disease's prevalence-;10 percent of individuals across the globe suffer from CKD-;there are limited tools for measuring cardiac risk for CKD patients, until now. (news-medical.net)
  • The ability to personalize risk assessment for individual patients with CKD is the first step toward scaling this for larger health systems. (news-medical.net)
  • This is a chance to earn a PhD from a leading university and by conducting a research project that will make a direct contribution to improving the health and care of patients. (findaphd.com)
  • This model will use data including age, PSA, DRE findings, prostate volume, and whole gland Micro-Ultrasound images to risk stratify patients following PSA screening. (pcf.org)
  • If successful, this project will improve understanding of tumor visibility by Micro-Ultrasound, and result in a 3-minute prostate scan and urine sample test that identifies patients at risk for prostate cancer and improves decisions on whether patients should undergo prostate biopsy or not. (pcf.org)
  • As part of this work, she developed a prognostic model to predict secondary cardiovascular risk in well-managed patients with established atherosclerotic disease. (ox.ac.uk)
  • Severe COVID-19 patients with combined oxygenation and ventilatory failure presented more severe pulmonary fibrosis, airway obstruction, and prolonged disease course. (bvsalud.org)
  • More than 23 000 patients were screened for cardiovascular diseases and more than 15 000 NCD consultations were provided. (who.int)
  • The presence of early pathology in the olfactory bulb of AD patients and early olfactory dysfunction, which may precede brain alterations, suggest a potential role of inhaled toxins as a risk factor for AD [ 11 ]. (biomedcentral.com)
  • 5. Assessment & treatment of cardiovascular disease in patients with chronic kidney disease. (ed.ac.uk)
  • Using meta-analyses we are exploring the therapeutic disenfranchisement that CKD patients suffer in terms of pharmacological management of their cardiovascular disease. (ed.ac.uk)
  • While current medications, such as statins, are often prescribed to lower 'bad cholesterol' in patients at higher risk of cardiovascular disease, these do not have any major or proven impact on elevated lipoprotein(a)," lead author Leon Simons, associate professor at the University of New South Wales, explained in a statement. (labpulse.com)
  • In particular, as a prognostic model for future patients, we describe how this framework can be used to predict survival for new patients who will only have baseline measurements. (biomedcentral.com)
  • Recent projects include the combination of computational modelling with interpretable machine learning in order to find easy to implement/deploy techniques for the identification of patients at risk for adverse events, as well as to improve our understanding of disease and decission making. (icrea.cat)
  • Between one and seven very high risk patients (three sub-groups of patients had this risk profile) were identified. (uwi.edu)
  • The NPV of identifying these high risk patients ranged from -$6748 to $14 725 and was favourable for three of the four monetary scenarios. (uwi.edu)
  • Recent large randomized controlled trials (RCTs) have shown that renal revascularization does not confer added benefit to unselected patients with atherosclerotic renovascular disease (ARVD) treated with multi-targeted medical therapy. (manchester.ac.uk)
  • Morbidity during the acute rehabilitation phase (which follows the initial acute hospitalization) includes pressure injury (pressure ulcer), which occurs in about 25% of patients treated in Model Systems centers in the United States. (medscape.com)
  • Pressure ulcers also were noted to be the most common morbidity in a study of patients monitored in Model Systems in the United States, occurring in 15% of patients during the first year post injury and increasing in subsequent years. (medscape.com)
  • There is an elevated risk for development of atherosclerosis/cardiovascular (CV) diseases among first responders (FR) who were present at Ground Zero over the first 72 hr. (cdc.gov)
  • 1.3 - Synergistic effects of a 'heart healthy' diet and statin therapy on atherosclerosis using a porcine model. (usda.gov)
  • A new proteomic risk model for cardiovascular disease was found to be more accurate than current methods of measuring cardiac risk, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. (news-medical.net)
  • The team, from Penn, Johns Hopkins, and the University of California San Francisco, used a drop of blood from participants to predict a patient's risk for a cardiac event. (news-medical.net)
  • Not only did the study indicate this model was more accurate compared to current approaches, the researchers were able to identify several proteins, like cartilage intermediate layer protein 2 (CILP2), that can be used in future research to identify cardiac risk or be the target for novel therapies. (news-medical.net)
  • Translational Cardiovascular Pathophysiology, focussing on assessing cardiac function and understanding changes induced by disease and how treatment can modulate this remodelling. (icrea.cat)
  • We also need to break down traditionally siloed disease and expertise specific domains, rising to the challenge of jointly addressing cancer, CVD, other complex diseases, their inter-relationships and their sequelae. (findaphd.com)
  • The Global Burden of Disease Study 1 estimated that in 2010 cardiovascular disease (CVD), including rheumatic heart diseases, hypertensive diseases, ischaemic heart diseases, pulmonary heart disease, other forms of heart disease, cerebrovascular diseases (CBVDs), diseases of arteries and diseases of veins, was the cause of death in approximately 30% of all global deaths. (bmj.com)
  • Health policy models are an important way to integrate complex patterns of risk exposure and disease burden with other population trends including income, education, aging, migration, and health care access. (washington.edu)
  • For this work, we will adapt econometric, geospatial, and epidemiologic modelling methods by leveraging the large data and computational resources of the Global Burden of Disease Study. (washington.edu)
  • Individually, each of these groups of diseases represents a burden at the individual and population level. (plos.org)
  • Discover how applying AI to healthcare can optimize the patient experience, drive efficiencies and reduce the burden of cardiovascular diseases on the global healthcare system. (techtarget.com)
  • Furthermore, it has been projected that the burden practices presents a number of development challenges. (who.int)
  • Researchers from the U.K. and Tufts University created a tool called the U.S. IMPACT Food Policy Model that included projections of U.S. demographics and cardiovascular death rates to 2030. (npr.org)
  • these markers could confer an increased risk to develop osteoporosis and other chronic diseases. (easp.es)
  • The need to counter the emerging pandemic of chronic diseases in low- and middle-income countries has also been highlighted in the Eleventh General Programme of Work, 2006-2015,1 which includes the target of reducing death rates from all chronic diseases by 2% per year over the next 10 years. (who.int)
  • Moreover, the simultaneous usage of different types of drugs for the treatment of various chronic diseases makes the patient health status even weaker [ 4 ]. (iospress.com)
  • SCORE2 and SCORE2-OP are calibrated to four European risk regions, based on age- and sex-standardized CVD mortality rates. (heartscore.org)
  • Cardiovascular diseases (CVDs) remain the prime cause of mortality worldwide, accounting for about a third of annual deaths [ 3 ]. (plos.org)
  • Those in the highest measure of predicted risk had an observed incident cardiovascular event rate of 60 percent over 10 years. (news-medical.net)
  • Here we use a mouse model of ischaemia-reperfusion injury to investigate new experimental medicine strategies to reduce the risk of developing CKD after AKI. (ed.ac.uk)
  • Objective To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. (bmj.com)
  • SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe. (heartscore.org)
  • In addition, we are utilising optical coherence tomography alongside established measures of cardiovascular risk to determine the impact of microvascular dysfunction in those with this condition. (ed.ac.uk)
  • The joint modelling of longitudinal and survival data is a valid approach to account for measurement error in the analysis of a repeatedly measured biomarker and a time-to-event. (biomedcentral.com)
  • A joint model of longitudinal and survival data consists of two component submodels: the longitudinal submodel and the survival submodel. (biomedcentral.com)
  • The longitudinal submodel allows us to model the trajectory of a repeatedly measured biomarker over time, adjusting for baseline covariates. (biomedcentral.com)
  • Of those thousands of proteins evaluated, researchers used machine learning methods to choose 32 proteins that comprised their proteomic risk model. (news-medical.net)
  • Climate Central used established scientific methods (more detail on the next page ) to take results averaged from 12 major global climate models and apply them to 21 American cities. (grist.org)
  • The current SCORE U54 program leverages over 15 years of our prior investment to create a disease-agnostic research program focused on sex differences and major medical conditions affecting women in the U.S. The former Specialized Centers of Research (SCOR) P50 program funded established scientists at centers across the country, with support from our NIH Institute and Center (IC) partners. (nih.gov)
  • The current ORWH SCORE program remains the only NIH centers program supporting disease-agnostic research on sex differences. (nih.gov)
  • In 2016, the World Health Organization (WHO) and the United States Centers for Disease Control (CDC) launched the Global Hearts initiative to support governments in their quest to prevent and control CVD. (cdc.gov)
  • 15-17 Employers and commercial insurers bear significant medical cost and productivity burdens associated with undertreatment of hypercholesterolemia and poor compliance with statins, particularly for the high-risk population. (ahdbonline.com)
  • Despite this, research has not focused enough on the life-course characterisation of the exposome and the application of this to health and disease. (europa.eu)
  • Many donors have wanted to support medical science or specifically cardiovascular disease research. (skr.fi)
  • Applications for the cardiovascular disease research grants could be submitted during the Finnish Cultural Foundation's regional funds' application round in January. (skr.fi)
  • The research project can help improve individual risk analysis and help direct treatment to individuals that benefit the most from it. (skr.fi)
  • The aim was to get applications from larger research projects and to achieve effectiveness", says Antti Niskanen , the fund officer in charge of the application process. (skr.fi)
  • The need for specific ethnic and cultural understanding and sensitivities was recognized from the onset, so the study has a community-based participatory research (CBPR) model. (wikipedia.org)
  • Each SCORE program has three highly integrated, synergistic research projects and an administrative core. (nih.gov)
  • Information on the research interests, projects, and members of Neeraj (Bean) Dhaun's Research Group. (ed.ac.uk)
  • My group's research focuses on the cardiovascular risk associated with the spectrum of chronic kidney disease (CKD) from early in the disease trajectory through to kidney failure requiring either dialysis or kidney transplantation. (ed.ac.uk)
  • Our research focuses on the intersection of nutrition/meal composition and its role in chronic disease. (tu.edu)
  • This programme offers the chance to carry out a doctoral research project at the leading edge of health data science. (findaphd.com)
  • Mi Jun's research interest is in the development and application of decision-analytics models for healthcare research. (ox.ac.uk)
  • The company has a wealth of experience in rare disease and pediatric research having managed about 100 projects in each area in the last five years alone. (xtalks.com)
  • Teams of research scientists from three universities will lead an innovative $15 million project to study the biological mechanisms of chronic stress that can increase cardiovascular disease risk. (healthliving101.com)
  • Two of the studies will be basic science research using mouse models - one examining hearts and gut bacteria to see if exercise can reverse the effects of stress on heart health and the other exploring how stress or exercise in a mouse mother can affect her offspring. (healthliving101.com)
  • This resulted in many international collaborations/publications/lectures as well as being requested by centres all over the world for advice on research in cardiovascular mechanics and imaging. (icrea.cat)
  • This paper describes the study protocol for EarlyCause, a large-scale and inter-disciplinary research project funded by the European Union's Horizon 2020 research and innovation programme. (plos.org)
  • In addition to their separate complexity, existing research has shown important multi-morbidity between these diseases, where multi-morbidity is defined as the co-occurrence of two or more chronic conditions [ 5 ]. (plos.org)
  • This presentation focuses on the regulatory aspects of bringing therapies for rare diseases to the market, specifically to identify how the regulatory pathways between Europe and US are similar and where there are differences. (xtalks.com)
  • Obesity is a progressive disease of excess adiposity that increases the risk of developing many types of cancer. (pbrc.edu)
  • We hypothesised that long term intake of low or high calcium increases the risk of cardiovascular mortality. (bmj.com)
  • Cross-sectional data of 981 PWH from the 2015-2017 Texas and Houston Medical Monitoring Projects were examined. (nih.gov)
  • 9 10 11 12 Lifetime risks which measure the cumulative risk of developing a disease during the remainder of an individual's life 13 would reflect this relatively high risk and, given that lifetime risk estimates provide assessment over the full life course, they may provide a more appropriate assessment of future risks than estimates limited to 10 years, particularly at younger ages. (bmj.com)
  • He is recognised as international expert in pathophysiological concepts and (image-based) assessment of CV diseases, with a reputation of being able to explain basic pathophysiology principles and put technical developments in context. (icrea.cat)
  • Micro-Ultrasound, possibly with a urine biomarker test, to accurately determine a patient's risk for prostate cancer and aid in decisions about whether to undergo prostate biopsy. (pcf.org)
  • One aspect of this work will be to re-evaluate the cardiovascular benefits and bleeding risks related to aspirin use from the patient's perspective. (ox.ac.uk)
  • The risk map leverages polygenic risk scores (PRS) to provide physicians with an understanding of a patient's absolute genetic risk of complex disease, allowing for the creation of early, personalized intervention strategies, the firm said. (labpulse.com)
  • Older women experience dramatic changes in the hypothalamic-pituitary-gonadal (HPG) axis and female reproductive hormones, producing vasomotor symptoms (VMS), sleep problems, cognitive changes, and cardiometabolic risks, which increase susceptibility to cardiovascular disease (CVD) and dementia. (nih.gov)
  • The local authority's vision may be better health for stopping communicable diseases. (who.int)
  • For those in industry, both the A hundred years ago, public health work was companies and the employees will benefit if they decisive in curbing communicable diseases. (who.int)
  • Prevalence of high CHOL or TG development was calculated using multivariable logistic regression model. (nih.gov)
  • The main objective of this study was to investigate the prevalence of T. gondii among adults in the United States and its association with cardiovascular health using data from the National Health and Nutrition Examination Survey (NHANES 2009-2010). (mdpi.com)
  • ANCA-associated vasculitis (AAV) is a rare, autoimmune disease that commonly involves the kidney. (ed.ac.uk)
  • Cardiovascular disease is the commonest complication of kidney disease and cardiovascular risk is greatest in those with kidney failure. (ed.ac.uk)
  • 2. The transition from acute kidney injury (AKI) through to chronic kidney disease. (ed.ac.uk)
  • 3. Chorioretinal thinning in chronic kidney disease. (ed.ac.uk)
  • Primary end-point measures included death, progression to end-stage kidney disease, cardiovascular events and a composite end-point composed of the first of any of the above events. (manchester.ac.uk)
  • Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease. (janusinfo.se)
  • Curcumin is a naturally occurring phenol found in the Indian spice turmeric that improves physiological function in animal models of age-related diseases and is a promising nutraceutical for intervention for promoting healthy aging. (sdsc.edu)
  • Drawing on lessons learned in phase 1 (years 2005-2008) of the HEART Project, we used an iterative, community- based process to develop an intervention based on an ecological framework. (cdc.gov)
  • Results of a trial using an intensive, 4-year program aimed at blood pressure lowering showed that intervention reduced not only blood pressure (BP), but also significantly reduced the risk of total dementia over that period. (medscape.com)
  • This new trial aimed to test the effectiveness of intensive BP intervention to reduce the risk of all-cause dementia and cognitive impairment over a 48-month intervention period vs usual care. (medscape.com)
  • In Paper III, a series of causal-inference experiments from VHU and publicly available genome-wide association study (GWAS) summary statistics were used to triangulate evidence of the direct and mediated effects by adiposity and physical activity, of macronutrient intake (fat, carbohydrates, protein and sugar) and cardiometabolic disease. (lu.se)
  • Using structural equation modelling, the mediation analyses enhanced with Mendelian randomization analysis, showed a likely causal putative association between carbohydrate intake and T2D. (lu.se)
  • In Paper IV, we conducted a systematic review and metanalysis of observational studies, complemented by Mendelian randomization analysis using GWAS summary statistics, investigating causal associations of individuals with high, yet normal, glycaemia associated with cardiovascular complications. (lu.se)
  • Taking a competing risk approach, the cause-specific hazards of a first event are modelled using parametric survival analysis. (bmj.com)
  • A more meaningful approach may be to provide costeffectiveness in terms that would allow employers and payers to project short-term impact on medical utilization and costs for budgetary purposes. (ahdbonline.com)
  • Future similarly targeted initiatives can benefit from an ecological approach that also embraces the promotora model. (cdc.gov)
  • 25] Post-SCI physical activity may play a therapeutic role as a effective countermeasure to these risks and often may be the first-line approach to CMS abatement. (medscape.com)