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  • nephron progenitor cells
  • Knockout and transgenic mouse models have clarified the genetic basis for many of these principles, and gene expression analyses have uncovered unanticipated distinctions between cell types in the developing kidney that were not apparent from morphological studies such as the arrangement of nephron progenitor cells in a series of molecularly distinct compartments ( 4 , 5 ). (pnas.org)
  • Formation of a sufficient number of nephrons during kidney development relies on a continuous supply of nephron progenitor cells. (pnas.org)
  • Populations
  • Hippocampal and hypothalamic progenitor cultures converged to indistinguishable populations and produced neurons of all three categories, confirming that even short-term culture confers or selects for immature progenitors with enough plasticity to elaborate neuronal phenotypes usually inhibited in vivo by the local microenvironment. (nih.gov)
  • Molecular genetic analysis of early outgrowth putative EPC populations suggests they do indeed have monocyte-like expression patterns, and support the existence of a separate population of progenitors, the late outgrowth, or endothelial colony forming cell (ECFC). (wikipedia.org)
  • differential
  • The sine oculis-related homeobox 2 (SIX2) transcription factor blocks the inductive activities of WNT signaling, and it has been suggested that the level of SIX2 expression in progenitor cells determines responsiveness to WNT9b, indicating that contradictory effects of Wnt9b may be explained by differential responsiveness of cells within cap mesenchyme ( 13 , 14 ). (pnas.org)
  • Airway epithelial progenitors are region specifi c and show differential responses to bleomycin-induced lung injury. (springer.com)
  • commonly
  • Genealogy (commonly known as family history), understands a progenitor to be the earliest recorded ancestor of a consanguineous family group of descendants. (wikipedia.org)
  • long
  • There are at least two different types of progenitors (sources) of GRBs: one responsible for the long-duration, soft-spectrum bursts and one (or possibly more) responsible for short-duration, hard-spectrum bursts. (wikipedia.org)
  • The progenitors of long GRBs are believed to be massive, low-metallicity stars exploding due to the collapse of their cores. (wikipedia.org)
  • These progenitor cells are easily identified by their long radial process. (wikipedia.org)
  • OPCs were long held to function purely as progenitors to oligodendrocytes, hence the name. (wikipedia.org)
  • Theoretical astronomers long believed the progenitor star for this type of supernova is a white dwarf and empirical evidence for this was found in 2014 when a Type Ia supernova was observed in the galaxy Messier 82. (wikipedia.org)
  • type
  • in other words, Type Ic have lost more of their envelope (i.e., much of the helium layer) than the progenitors of Type Ib. (wikipedia.org)