alpha 1-Antitrypsin Deficiencyalpha 1-AntitrypsinLiverPulmonary EmphysemaEmphysemaLiver DiseasesPhenotypeLiver CirrhosisPulmonary Disease, Chronic ObstructiveTrypsin Inhibitorsalpha 1-AntichymotrypsinLiver TransplantationForced Expiratory VolumePancreatic ElastaseHeterozygoteLung DiseasesHomozygoteProteostasis DeficienciesHepatitisLiver NeoplasmsBronchiectasisAllelesMutationSerpinsLungSmokingGenotype