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AdenosineReceptor, Adenosine A2AReceptor, Adenosine A1Adenosine DeaminaseReceptor, Adenosine A3Receptor, Adenosine A2BAdenosine KinaseReceptors, Adenosine A2Adenosine A2 Receptor AgonistsAdenosine A2 Receptor AntagonistsReceptors, Purinergic P1Adenosine A1 Receptor AntagonistsAdenosine A1 Receptor AgonistsPurinergic P1 Receptor AntagonistsXanthinesPurinergic P1 Receptor AgonistsAdenosine MonophosphateAdenosine-5'-(N-ethylcarboxamide)TheophyllineAdenosine A3 Receptor AntagonistsReceptors, PurinergicAdenosine A3 Receptor AgonistsPhenethylamines2-ChloroadenosinePhenylisopropyladenosineInosine5'-NucleotidaseCyclic AMPAdenosine TriphosphatasesTubercidinAdenine NucleotidesNucleoside DeaminasesCoformycinDipyridamoleTheobrominePentostatinAdenosine PhosphosulfateKineticsDose-Response Relationship, DrugPurinesTriazinesAdenineThioinosineCells, CulturedDeoxyadenosinesVasodilator AgentsPurinergic AntagonistsAminophyllineRats, Sprague-DawleyHypoxanthineNucleotidasesTime FactorsNucleoside Transport ProteinsMolecular Sequence DataHypoxanthinesTriazolesNucleosidesApyraseCalciumGuinea PigsRabbitsRats, WistarCoronary CirculationAdenylate CyclaseDogsBucladesineMyocardiumRibonucleosidesCell LineReceptors, Purinergic P2AdenosylhomocysteinaseSignal TransductionNucleotidesBase SequenceMagnesiumExtracellular SpaceMice, Inbred C57BLCaffeineVasodilationColforsin8-Bromo Cyclic Adenosine MonophosphateMutationRNA, MessengerEnzyme Inhibitors1-Methyl-3-isobutylxanthineAmino Acid SequenceRats, Inbred StrainsHyperemiaPerfusionIsoproterenolEscherichia coliHeartRadioligand AssayHydrogen-Ion ConcentrationCattleNorbornanesPhosphodiesterase InhibitorsCell MembraneS-AdenosylhomocysteineRNA Editing
PurineReceptor
Purine1
  • Recent studies have built upon decades of evidence that adenosine, a purine nucleoside that can act as a neuromodulator, is involved in pain transmission and sensitization. (mdpi.com)
Receptor4
  • The adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human adenosine A2b receptor gene which encodes it. (wikipedia.org)
  • Research into selective A2B ligands has lagged somewhat behind the development of ligands for the other three adenosine receptor subtypes, but a number of A2B-selective compounds have now been developed, and research into their potential therapeutic applications is ongoing. (wikipedia.org)
  • BAY 60-6583 NECA (N-ethylcarboxamidoadenosine) (S)-PHPNECA - high affinity and efficacy at A2B, but poor selectivity over other adenosine receptor subtypes LUF-5835 LUF-5845 - partial agonist Compound 38: antagonist, high affinity and good subtype selectivity ISAM-R56A: non-xanthinic high affinity selective antagonist (Ki: 1.50 nM) ISAM-140: non-xanthinic selective antagonist (Ki = 3.49 nM). (wikipedia.org)
  • This is further supported by the widespread use of caffeine, an adenosine receptor antagonist, in several headache treatments. (mdpi.com)