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  • Leukemic
  • Our study indicates that signal transduction and mitochondrial ATP production are essential during adaptation of leukemic cells to vincristine, these processes represent potential therapeutic targets. (elsevier.es)
  • Physiology
  • Additional biology classes such as Cell Biology, Genetics, Anatomy and Physiology, or Microbiology can be helpful, but aren't required. (kaptest.com)
  • maturation
  • The glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation," Reproductive Biology and Endocrinology , vol. 6, article 17, 2008. (hindawi.com)
  • These processes, and how they integrate with NK cell maturation, are currently poorly understood. (rupress.org)
  • A central issue in murine NK cell development concerns how Ly49 receptor expression is coupled to NK cell maturation and education processes. (rupress.org)
  • asymmetric cell div
  • Unlike normal cell division, which creates two identical daughter cells, the division of stem cells is asymmetric cell division . (biologydictionary.net)
  • The uneven distribution of EGFR-3 suggested that the protein might be involved in a phenomenon known as asymmetric cell division , which along with symmetric cell division constitute the two ways that cells make copies of themselves. (phys.org)
  • In asymmetric cell division, the mother cell divides into two daughter cells that have different fates - one might be a neoblast, another a muscle cell or photoreceptor cell. (phys.org)
  • Even though asymmetric cell division has long been proposed to exist in planarians, our study provides the first direct molecular evidence of its existence," says Lei. (phys.org)
  • He showed that when EGFR-3 was functioning normally, irradiated neoblasts divided by asymmetric cell division half of the time and by symmetric cell division the other half of the time. (phys.org)
  • acute lymphobl
  • Genomic alterations in B cell differentiation factors such as PAX5, IKZF1, and EBF-1 have been identified in more than half of all cases of childhood B precursor acute lymphoblastic leukemia (ALL). (rupress.org)
  • influences
  • These immature populations generally differentiate into T cells when placed in a thymic environment and NK cells when placed into other environments, suggesting that the environment in which the cells develop influences their ultimate fate. (rupress.org)
  • Hormonal influences also play a role in the differentiation process: estrogen's, progesterone, testosterone, and others must be present in sufficient quantities to assist in the synthesis of the thrombocytes. (enotes.com)
  • photoreceptor cell
  • The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. (zfin.org)
  • populations
  • Circulation cytometry examination of CD24+ and CD44+ sub-populations of TW02 and TW04 cells. (idhinhibitor.com)
  • When the embryo has become a solid mass of blastomeres (called a morula), it generally consists of two or more differently committed cell populations-a result of the blastomeres having incorporated different cytoplasmic determinants. (britannica.com)
  • tissue
  • The hormones and environment here directs the cells to become vascular tissue and supporting cells. (biologydictionary.net)
  • Two cell lines were studied which secreted smaller than normal IgM heavy chains in tissue culture. (arizona.edu)
  • One cell line studied (208) contains one glycosylation site, while another (562) retains three sites on the molecule synthesized in tissue culture. (arizona.edu)
  • Studies performed on these cell lines in tissue culture indicate greater processing of the oligosaccharides on these mutant IgM molecules when compared to the parental cell line (PC700). (arizona.edu)
  • pathway
  • Following treatment with the Wnt inhibitor for 7 days (ten mM), sphere dimensions was significantly reduced by an typical of twenty% and forty five% in TW02 and TW04 cells, respectively (Figure 3D), suggesting that the Wnt pathway might add to the CSC phenotype of CD24+ cells.previous cultures of CD24+ and CD242 cells by movement cytometry. (idhinhibitor.com)
  • Development
  • After winter, or anytime the environment is prime, the seed will soak up moisture and restart the process of development. (biologydictionary.net)
  • The clone development efficiency (CFE) of CD24+ cells was also decided. (idhinhibitor.com)
  • Unlike T cells, NK cells require neither a thymus (( 9 )) nor V(D)J recombination (( 10 )) for their development. (rupress.org)
  • This presentation is an overview for the major challenges, including vector and host engineering, clone selection and cell line stability, cell banking, platform medium and process development, product quality assessment and their future trends. (selectbiosciences.com)
  • molecular
  • 2-4 Although much progress has been achieved in the detailed characterization of the molecular processes directly involved in drug tolerance of cancer cells, 5,6 more research is needed to develop effective therapeutic strategies to resensitize chemoresistant cells. (elsevier.es)
  • We compared the molecular nature of murine KIT mutants with the number of mast cells in thier skin. (nii.ac.jp)
  • terminally
  • The RGCs and RPE cells are terminally differentiated cell lineages that cannot be regenerated, and therefore their progressive loss eventually leads to irreversible blindness. (biomedcentral.com)
  • p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. (semanticscholar.org)
  • regenerative medicine
  • The finding, which appears online August 11, 2016, in the journal Developmental Cell , has important implications for advancing regenerative medicine and for developing more effective cancer therapies. (phys.org)
  • murine
  • In order to study glycoprotein biosynthesis and processing, we have chosen the murine Immunoglobulin M (IgM) system as a model. (arizona.edu)
  • dendritic
  • Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance," Immunity , vol. 36, no. 3, pp. 438-450, 2012. (hindawi.com)
  • Methods
  • Alvetex® scaffold technology provides a solution for generating real three dimensional (3D) cell culture simply and routinely, overcoming the limitations imposed by conventional culture methods. (selectbiosciences.com)
  • Phenotypes
  • This presentation will review the use of proteomics technology to better understand bioprocess-relevant phenotypes and to investigate the impact of MicroRNAs (miRNAs) on the proteome of recombinant Chinese hamster ovary cell lines. (selectbiosciences.com)