Apoptosisbcl-2-Associated X ProteinCaspase 3Proto-Oncogene Proteins c-bcl-2Apoptosis Regulatory ProteinsCaspasesbcl-X ProteinDNA FragmentationCaspase 9Cytochromes cIn Situ Nick-End LabelingMitochondriaCell Line, TumorCell SurvivalTumor Suppressor Protein p53Signal TransductionBlotting, WesternCell ProliferationCell CycleProto-Oncogene ProteinsAntigens, CD95PhagocytosisCaspase InhibitorsRNA, Transfer, ProApoptotic Protease-Activating Factor 1Annexin A5Cells, CulturedNecrosisJurkat CellsCaspase 8PhosphatidylserinesCell DeathEnzyme ActivationFlow CytometryFas Ligand ProteinTumor Cells, CulturedCell LineCysteine Proteinase InhibitorsAmino Acid Chloromethyl KetonesPoly(ADP-ribose) PolymerasesMolecular Sequence DataMice, Inbred C57BLMacrophagesCaspase 7Time FactorsStaurosporineAntineoplastic AgentsProlineImmunohistochemistryCytochrome c GroupMembrane Potential, MitochondrialAmino Acid SequenceCaspase 2Caspase 6Enzyme InhibitorsReactive Oxygen SpeciesDose-Response Relationship, DrugDNA Damagebcl-2 Homologous Antagonist-Killer ProteinDNATransfectionTumor Necrosis Factor-alphaBH3 Interacting Domain Death Agonist ProteinCell DivisionHL-60 CellsGenes, bcl-2Cysteine EndopeptidasesMice, KnockoutInhibitor of Apoptosis ProteinsAntibodies, MonoclonalHeLa CellsRNA, MessengerTropaeolaceaeReverse Transcriptase Polymerase Chain ReactionPlant ExtractsModels, MolecularBase SequenceMutationApoptosis Inducing FactorStereoisomerismAntineoplastic Agents, PhytogenicTNF-Related Apoptosis-Inducing LigandDown-RegulationCell Nucleusbcl-Associated Death ProteinMice, Inbred BALB CMembrane ProteinsMembrane GlycoproteinsPropidiumPhosphorylationRNA, Small InterferingUp-RegulationRecombinant ProteinsMagnetic Resonance SpectroscopyPhagocytesOxidative StressMolecular StructureGene Expression RegulationCarrier ProteinsRats, Sprague-Dawley