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  • pathology
  • Pathology and genetics, tumors of the nervous system. (springer.com)
  • In: Tumors of the fetus and newborn, vol 35, Major problems in pathology. (springer.com)
  • I discuss issues pertaining to the practice of neuropathology -- including nervous system tumors, neuroanatomy, neurodegenerative disease, muscle and nerve disorders, ophthalmologic pathology, neuro trivia, neuropathology gossip, job listings and anything else that might be of interest to a blue-collar neuropathologist. (blogspot.com)
  • Surgical Neuropathology Update: A Review of Changes Introduced by the WHO Clas sification of Tumors of the Central Nervous System, 4th edition " in Archives of Pathology and Laboratory Medicine: 2008;132: 993-1007). (blogspot.com)
  • suppressor
  • AT/RT has been linked to somatic and germline mutations of SMARCB1 and, less commonly, SMARCA4 , both of which are tumor suppressor genes. (cancer.gov)
  • Although germ-line mutations in INI1 were not observed, the homozygous loss or inactivation of the INI1 gene is consistent with its function as a tumor suppressor gene. (aacrjournals.org)
  • The purpose of this study was to determine whether INI1 is a candidate tumor suppressor gene for AT/RTs of the brain. (aacrjournals.org)
  • The SUFU gene is a tumor suppressor that encodes a negative regulator protein of the hedgehog signaling pathway. (invitae.com)
  • desmoplastic
  • Two of the more common infantile brain tumors, glioblastoma multiforme (GBM) and desmoplastic infantile tumors (DITs), can be difficult to distinguish on MRI. (thejns.org)
  • Of 70 cases of infantile brain tumors, 2 GBM cases and 3 DIT cases (all 3 of which were desmoplastic infantile gangliogliomas [DIGs]) met the inclusion criteria. (thejns.org)
  • Diagnosis
  • In two North American prospective studies performed by the Children's Cancer Group and the Pediatric Oncology Group for children aged 3 years or younger at diagnosis, retrospective review disclosed that approximately 10% of children with brain tumors had AT/RTs. (cancer.gov)
  • Endoscopic cyst fenestration and tumor biopsy was performed, and pathological diagnosis was tentatively oligodendroglioma based on the presence of tumor cells with a perinuclear halo. (readbyqxmd.com)
  • Cancer
  • Each unique tumor model and its biological characteristic data is available to all academically qualified petitioners-opening the door for breakthroughs in childhood cancer research. (alexslemonade.org)
  • Other lesions may mimic squamous cell cancer and invade the larynx, and these include thyroid cancer as well as chondroid tumors from the adjacent thyroid cartilage. (ucsd.edu)
  • infantile
  • The authors report on their institutional experience with both tumors, focusing on radio-graphic features, especially the diffusion studies, which might be useful in distinguishing between infantile GBM and DIT. (thejns.org)
  • A retrospective review was undertaken of all infantile brain tumors treated at British Columbia's Children's Hospital between 1982 and 2012, and cases of GBM and DIT were recorded. (thejns.org)
  • Magnetic resonance imaging, especially diffusion-weighted imaging, may be a useful aid in distinguishing between infantile GBM and DIT tumors, with infantile GBM demonstrating restricted diffusion. (thejns.org)
  • Coffin CM (2007) Infantile soft tissue tumors. (springer.com)
  • cancerous
  • Nevoid basal cell carcinoma syndrome ( NBCCS ), also called Gorlin syndrome, is an inherited, multisystemic disorder that is associated with an increased risk of certain cancerous and noncancerous tumors. (invitae.com)