• Humans and other primates cannot synthesize ascorbic acid due to a deficiency of a specific enzyme, which is why vitamin C is necessary for wound healing, plays a role in iron absorption, and acts as a prophylactic agent against scurvy. (libertyiv.com)
  • It is important to note that ascorbic acid is not the same thing as vitamin C, which is a complex of nutrients, enzymes, coenzymes, antioxidants, and trace minerals. (libertyiv.com)
  • Some companies add natural ingredients to ascorbic acid and call it natural vitamin C, but the proportions of these natural ingredients are often not the same as they are in nature, and it is important to get a balanced complex of nutrients, not just isolated ascorbic acid. (libertyiv.com)
  • Natural vitamin C is more expensive to produce but is worth it for optimal health as it is better absorbed and utilized by the body than synthetic ascorbic acid, which can deplete the body of other important nutrients and lacks the full complex. (libertyiv.com)
  • James Lind is known for his work on the substitution of vitamin C in the English Navy, and Linus Pauling first advocated for the consumption of high doses of ascorbic acid to prevent and treat the common cold. (libertyiv.com)
  • Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin and a powerful antioxidant . (foodrevolution.org)
  • Vitamin C boosts iron absorption , which can help prevent iron deficiency. (foodrevolution.org)
  • Vitamin C also known as Ascorbic Acid and several other names, is an essential nutrient for higher primates, and a small number of other species. (upcfoodsearch.com)
  • Vitamin C also aids in the absorption of iron, and helps maintain capillaries, bones, and teeth. (upcfoodsearch.com)
  • Then, from 1928 to 1933, the Hungarian research team of Joseph L Svirbely and Albert Szent-Gyorgyi and, independently, the American Charles Glen King, first isolated vitamin C and showed it to be ascorbic acid. (upcfoodsearch.com)
  • Chemistry - A water soluble vitamin, ascorbic acid occurs as white to slightly yellow crystal or powder. (elephantcare.org)
  • Pharmacokinetics - Vitamin C is generally well absorbed in the jejunum (human data) after oral administration, but absorption may be reduced with high doses as an active process is involved with absorption. (elephantcare.org)
  • Vitamin C may be synergistic with deferoxamine in removing iron, but may in fact, lead to increased iron tissue toxicity especially in cardiac muscle. (elephantcare.org)
  • Scurvy is a state of dietary deficiency of vitamin C (ascorbic acid). (medscape.com)
  • Consumption of fruits and vegetables or diets fortified with vitamin C is essential to avoid ascorbic acid deficiency. (medscape.com)
  • Plasma ascorbic acid level may help in establishing the diagnosis, but this level tends to reflect the recent dietary intake rather than the actual tissue levels of vitamin C. Signs of scurvy can occur with low-normal serum levels of vitamin C. (medscape.com)
  • [2] In the 1920s, Albert Szent-Györgyi, a Hungarian biochemist, discovered the molecular structure of vitamin C and named it ascorbic acid, meaning anti-scurvy. (statpearls.com)
  • Exogenous vitamin C is necessary only for humans and other primates. (statpearls.com)
  • Humans lack the active form of the enzyme L -gulonolactone oxidase required for synthesizing ascorbic acid, making it essential to acquire vitamin C from dietary sources or supplements. (statpearls.com)
  • The absorption of the vitamin is efficient at dosages up to 100 mg/d. (statpearls.com)
  • Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits and vegetables, also sold as a dietary supplement and as a topical "serum" ingredient to treat melasma (dark pigment spots) and wrinkles on the face. (wikipedia.org)
  • Most animals are able to synthesize their own vitamin C. However, apes (including humans) and monkeys (but not all primates), most bats, some rodents, and certain other animals must acquire it from dietary sources. (wikipedia.org)
  • Doing so converts vitamin C to an oxidized state - either as semidehydroascorbic acid or dehydroascorbic acid. (wikipedia.org)
  • Vitamin C (ascorbic acid) is an essential nutrient with a number of beneficial effects on the human body. (scholars.direct)
  • Vitamin C also affects hematopoiesis by enhancing the absorption of iron from the small intestine by reducing dietary iron from the ferric form to the ferrous form. (medscape.com)
  • This may contribute to the anemia seen with vitamin C deficiency, in which the availability of intracellular iron is reduced. (medscape.com)
  • Vitamin C is an important nutrient for the body, and it has a wide range of benefits including supporting the immune system, helping to maintain healthy skin and connective tissue, and aiding in the absorption of iron. (choicenutrition.ca)
  • Dr. Jungblut, an early pioneer of vitamin C therapy in the 1930's, discovered that only we primates and guinea pigs were susceptible to scurvy as well as anaphylactic shock, pulmonary tuberculosis, diptheritic intoxication, a poliomyelitis-like viral infection and a viral form of leukemia. (choicenutrition.ca)
  • Vitamin C (English: Vitamin C / ascorbic acid, also known as L-ascorbic acid, also known as vitamin C) is an essential nutrient for higher primates and a few other organisms. (plantextract-powder.com)
  • C Vitamin Ascorbic Acid Powder can improve the immunity of the human body. (plantextract-powder.com)
  • The human body's white blood cells are rich in L(+)-Ascorbic acid Vitamin C Powder. (plantextract-powder.com)
  • The strength of the vessel wall has a lot to do with L(+)-Ascorbic acid Vitamin C Powder. (plantextract-powder.com)
  • Vitamin C (ascorbic acid) is an essential water-soluble micronutrient that has had a dramatic influence on world history. (selfhacked.com)
  • Vitamin C contributes to many important enzyme reactions, including those leading to the synthesis of norepinephrine, carnitine , cholesterol, amino acids, and several peptide hormones [ 5 ]. (selfhacked.com)
  • A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. (lookformedical.com)
  • An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. (lookformedical.com)
  • Dietary absorption of VITAMIN C is highly dependent upon this class of transporters and a subset of SODIUM GLUCOSE TRANSPORTERS which transport the oxidized form of vitamin C, DEHYDROASCORBIC ACID. (lookformedical.com)
  • Vitamin C (L-ascorbic acid, ascorbate), a water-soluble micronutrient essential for humans, is a six-carbon α-ketolactone weak acid with a pH of 4.2 and a molecular weight of 176 ( Fig. 29.1 ). (basicmedicalkey.com)
  • Vitamin C is not synthesized by humans and nonhuman primates because of their lack of gulonolactone oxidase, the terminal enzyme in the biosynthetic pathway of vitamin C from glucose. (basicmedicalkey.com)
  • With loss of the first electron, vitamin C oxidizes to the ascorbate free radical (semidehydroascorbic acid). (basicmedicalkey.com)
  • A study in the Journal of Investigative Dermatology showed that a combination of vitamin C, E and ferulic acid not only offered improved stability of vitamins C and E but also improved skin's UV protection. (vitaminproguide.com)
  • As part of their adaptation from marine life, terrestrial plants began producing non-marine antioxidants such as ascorbic acid ( vitamin C ), polyphenols and tocopherols . (wikipedia.org)
  • Several studies have shown that vitamin C helps uric acid in the blood, providing protection from gout attacks. (natureknowsproducts.com)
  • One study found that vitamin C consumption results in significantly lowered uric acid levels in the blood. (natureknowsproducts.com)
  • In addition, an analysis of 13 studies found that taking a vitamin C supplement over a span of 30 days reduces blood uric acid when compared to a placebo. (natureknowsproducts.com)
  • Despite strong links between vitamin C and uric acid blood levels, more studies are needed to fully understand vitamin C's effects on gout. (natureknowsproducts.com)
  • If you are following a meat-free diet, then it is good to know that vitamin C supplements aid in improving iron absorption, especially from plant-based sources. (natureknowsproducts.com)
  • In fact, just consuming 100mg of vitamin C improves iron absorption by 67 percent, helping reduce the risk of anemia for those suffering from iron deficiency. (natureknowsproducts.com)
  • Primate lineage lost ability to synthesize Vitamin C from glucose 66 million years ago with loss of l-gulonolactone oxidase enzyme. (meatrition.com)
  • Involved in collagen biosynthesis: vitamin c dependent hydroxylation occurs during collagen synthesis by keeping iron in a reduced (ferrous state), which allows for production of hydroxyproline and hydroxylysine. (meatrition.com)
  • Vitamin C acts as reductant keeping iron in a ferrous state (active state). (meatrition.com)
  • Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. (lookformedical.com)
  • Though ubiquitous, ascorbate is not produced by humans, guinea pigs, some primates, a particular type of fruit eating bat, the majority of fishes and birds [ 2 ], who depend on diet for the assumption and use of this fundamental nutrient. (scholars.direct)
  • Pharmacology - Exogenously supplied ascorbic acid is a dietary requirement in some exotic species (including rainbow trout, Coho salmon), guinea pigs, and in primates. (elephantcare.org)
  • It isn't a necessary component of diet, at least for all mammals with the exception of guinea pigs, fruit eating bats, the red vented bulbul bird and primates - which includes us. (choicenutrition.ca)
  • It may also be involved with some oxidation-reduction reactions, and is involved with the metabolism of many substances (iron, folic acid, norepinephrine, histamine, phenylalanine, tyrosine, some drug enzyme systems). (elephantcare.org)
  • [ 7 ] The enzyme L-gluconolactone oxidase, which would usually catalyze the conversion of L-gluconogammalactone to L-ascorbic acid, is defective due to a mutation or inborn error in carbohydrate metabolism. (medscape.com)
  • a key enzyme for the synthesis of DHA and sapienic acid. (ocl-journal.org)
  • One of these enzymes, or part of the enzyme system, is missing in primates. (choicenutrition.ca)
  • An enzyme involved in the metabolism of ASCORBIC ACID and aldarate. (lookformedical.com)
  • The gulonolactose oxidase gene became nonfunctional in a common primate ancestor ( 5 ). (basicmedicalkey.com)
  • The investigation lasted for eight weeks and subjects were randomly assigned to receive either a protein- and energy-dense supplement enriched with omega-3 fatty acids and antioxidants or a control supplement. (questhealthlibrary.com)
  • The conclusion of the study stated that while omega-3 fatty acids did not provide a therapeutic advantage over the control supplement, omega-3 supplementation caused a dose-dependant gain in weight and lean body mass. (questhealthlibrary.com)
  • Fish is the best source of omega-3 and the 28g of fish in the EAT diet provides 284mg of omega-3 fatty acids vs. an RDA of 1.6g for adult males (Ref 3). (zoeharcombe.com)
  • Limited amounts of ascorbic acid to a dose range of 300 mg to 2000 mg daily, in divided doses, have been capable of hastening the healing of wounds by producing healthy granulation tissue and also by reducing local edema. (health-matrix.net)
  • This could conceivably have been an advantage for primates or other species. (choicenutrition.ca)
  • Much human behaviour has characteristics that we share with other species among the primates, the order to which Homo sapiens belongs. (cambridge.org)
  • But we share the way we feed our young much more widely with other species of mammals, the class to which the primates belong. (cambridge.org)
  • GOLDENOIL is a high quality feeding oil rich in the essential fatty acid Linoleic acid necessary for the transport of fats and the maintenance and repair of the membrane that encloses the cell. (trinity-consultants.com)
  • Fatty foods are sensitive to photooxidation, [16] which forms hydroperoxides by oxidizing unsaturated fatty acids and ester . (wikipedia.org)
  • Omega-3 - essential fatty acids. (zoeharcombe.com)
  • Unfortunately, the tool doesn't aggregate to the fatty acid level, but this diet is highly likely deficient in omega-3 and highly likely (given the 350 calories of nutritionally poor, highly unsaturated, vegetable oils) has an unhealthy omega-6 to omega-3 ratio. (zoeharcombe.com)
  • 1984. "Men who developed coronary heart disease also had a higher mean intake of percentage of calories from protein, fat, saturated fatty acids, and polyunsaturated fatty acids than men who remained free of coronary heart disease. (blogspot.com)
  • Excess amounts of ascorbic acid are excreted unchanged or as metabolites. (medscape.com)
  • I have analysed separately the 7g beef, 7g pork, 29g chicken and 28g of fish, to find the maximum amount of heme iron (some of the iron in these foods is non-heme) and it amounts to 1.1mg - just 6% of the iron intake recommended. (zoeharcombe.com)
  • [12] These preservatives include natural antioxidants such as ascorbic acid (AA, E300) and tocopherols (E306), as well as synthetic antioxidants such as propyl gallate (PG, E310), tertiary butylhydroquinone (TBHQ), butylated hydroxyanisole (BHA, E320) and butylated hydroxytoluene (BHT, E321). (wikipedia.org)
  • Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. (lookformedical.com)
  • Iron is an essential nutrient that has various functions, including red blood cell production and transportation of oxygen throughout your body. (natureknowsproducts.com)
  • Its neutralizing action on certain toxins, exotoxins, virus infections, endotoxins and histamine is in direct proportion to the amount of the lethal factor involved and the amount of ascorbic acid given. (health-matrix.net)
  • Given that the rest of the iron is non-heme, the deficiency is far greater than the number 88% suggests, as the requirement is 1.8 times higher. (zoeharcombe.com)
  • 1997. Inhibition of L-aromatic amino acid decarboxylase by polychlorinated biphenyls. (cdc.gov)
  • One manifestation of negative selection in the globins is that minimal 3-base type amino acid replacements occur less frequently than would be expected if base replacements had occurred and were accepted at random. (pharmaceuticalintelligence.com)
  • Accelerated rates of globin evolution were found in lineages of cold-blooded vertebrates, some marsupials, and early placental mammals, while slower rates were found in warm-blooded vertebrates, especially higher primates. (pharmaceuticalintelligence.com)
  • Ascorbic acid will slowly darken upon light exposure. (elephantcare.org)
  • 1976. Pathobiological responses of primates to polychlorinated biphenyl exposure. (cdc.gov)
  • Ascorbic acid is widely distributed and only about 25% is bound to plasma proteins. (elephantcare.org)
  • Twenty brands of herbal remedies were purchased randomly from the Pharmacy shops in Lagos, digested with aquaregia (3:1 HCl: HNO3) and were analysed using atomic absorption spectroscopy (Buck 205 Atomic Absorption Spectrophotometer). (cput.ac.za)
  • Ascorbic acid will repair and maintain the integrity of the capillary wall. (health-matrix.net)
  • Ascorbic acid is prone to oxidation in vivo, and body stores are affected by environmental and lifestyle factors (eg, smoking), biological conditions (eg, inflammation, iron excess), and pathologic conditions (eg, malabsorption) that may alter its oxidation. (medscape.com)
  • A type of waste product produced by your body, uric acid may crystallize and deposit in your joints at high levels. (natureknowsproducts.com)
  • Here the historical diets of several populations of ruffed lemurs across UK zoological collections are described, highlighting differences in nutritional content with a focus on the problems of obesity and iron storage disease. (researchgate.net)
  • There is an increase demand for ascorbic acid in burns especially when epithelization and formation of granulation tissue are taking place. (health-matrix.net)
  • For instance, eating a combination of tomatoes and lentils, or tomatoes and beans, at the same time, can enhance how much iron you absorb. (foodrevolution.org)
  • Reducing the relative proportion of sugar-rich fruit, removing food items high in iron and limiting daily iron to 2 mg per individual may be an effective means of decreasing the prevalence of obesity and ISD in the captive population. (researchgate.net)
  • Comparative calculations were conducted to investigate differences in the amount of metabolisable energy, carbohydrates, sugar and iron provisioned per individual per day, between institutions. (researchgate.net)