Primate cloning clone. Medical search. Frequent questions

Since the embryos had adult DNA, the resulting stem cells became clones of the adult somatic cells. (wikipedia.org)
The phrase "produced from the nuclear DNA from non-germ cells of a single sexually mature adult" means that the rhesus monkey experiment performed at the Oregon Primate Research Center involving reproduction of embryos does not satisfy the claim. (ideosphere.com)
It took 127 eggs and 79 embryos to get these results, and it still required a fetus to work (Dolly was cloned from an adult). (engadget.com)
In January 2006, Hwang's home research institution, Seoul National University, delivered a damning report about Hwang's work on cloned human embryos, concluding it was all based on fraudulent data. (nature.com)
They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
Scientists want to make cloned human embryos to get embryonic stem cells, which live inside early embryos and have the potential to cure a wide array of diseases. (irfi.org)
A) a diagram of the cloning procedure using SCNT, B) the cloned embryos at different stages of development, and C) the five cloned monkeys. (inverse.com)
Then, in February 2004 he dropped a bombshell, claiming that his SNU research team had cloned the first human embryos and extracted stem cells from them. (koreatimes.co.kr)
The recent desperation to clone human embryos may be seriously undermining accepted ethical principles of medical research, with potentially profound wider consequences. (lifeissues.net)

Ever since cloning produced Dolly the sheep , scientists have copied a slew of mammals ranging from dogs to ponies. (engadget.com)
Chinese researchers have successfully cloned a macaque monkey fetus twice, producing sister monkeys Hua Hua and Zhong Zhong using the same basic method used to create Dolly. (engadget.com)
This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
Even the world's most famous sheep clone, Dolly, who died recently suffered from problems linked to this gene. (irfi.org)
It seems that a little knowledge is a dangerous thing, and the authors have allowed themselves to over-interpretate their interesting results,' said Professor Ian Wilmut of the Roslin Institute, in Edinburgh, leader of the team, which cloned Dolly the sheep. (irfi.org)
The birth of Dolly the Sheep in July 1996 transformed animal cloning from science fiction into science fact. (medpagetoday.com)
It became a hot topic in 1996 when Dolly the sheep was cloned via a process called somatic cell nuclear transfer. (archstl.org)
The researchers used somatic cell nuclear transfer, the same technique used to clone Dolly the sheep more than two decades ago, to clone the monkey and produce five cloned offspring. (inverse.com)

With Hwang discredited, both the field of therapeutic cloning and the public's trust in science have suffered a serious setback. (nature.com)
The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
Reproductive cloning in humans and therapeutic cloning in primates: is the ethical debate catching up with the recent scientific advances? (bmj.com)
Finally, and inexorably, a true professional scientist poses clearly challenging questions to his research colleagues, and to the scientific enterprise in general, about the dubious "scientific" justification for the current rush to clone human beings - for both "therapeutic" and for "reproductive" purposes. (lifeissues.net)
But he is equally concerned about the unethical aspects inherent in the rush to perform " therapeutic " human cloning research, including the abuses to all vulnerable human patients who would be required to participate in clinical trials. (lifeissues.net)

This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)

The Hwang affair, or Hwang scandal, or Hwanggate, is a case of scientific misconduct and ethical issues surrounding a South Korean biologist, Hwang Woo-suk, who claimed to have created the first human embryonic stem cells by cloning in 2004. (wikipedia.org)
The research, published in the 12 March 2004 issue of Science, was reported as "Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst. (wikipedia.org)
It was the first instance of cloning of adult human cells and human embryonic stem cells. (wikipedia.org)
SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
That's why Father Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia, said that the efforts to help people understand the immorality of embryo reserch, including human cloning, must focus on humanizing the issue and appreciating our own embryonic origins, not just on the desired results of embryonic or other types of stem-cell research. (archstl.org)
A decade later, cloning came to the forefront in Missouri with the narrow passage of Amendment 2, a ballot initiative in 2006 that constitutionally protects embryonic stem-cell research and human cloning. (archstl.org)

In theory, this makes human cloning more realistic given the genetic similarities between monkeys and our own species. (engadget.com)
The new work by scientists in Pittsburgh provides an explanation for why hundreds of attempts to clone monkeys have all failed despite successes in several other mammals. (irfi.org)
The scientists said they suspect that similar roadblocks exist for all primates -- the evolutionary grouping that includes monkeys and humans. (irfi.org)
For one thing, the team used the cloned monkeys' resulting psychiatric disorders - including "behaviors resembling anxiety, depression, and schizophrenia" - as signs that they had performed the experiment successfully. (inverse.com)
The researchers are undeterred, as the benefits of the cloned monkeys could be significant for drug research. (inverse.com)
After all, large groups of cloned animals would help eliminate some of the variation that occurs in animal trials, since all of the monkeys would be expected to respond to a drug in the exact same way. (inverse.com)
Without the interference of genetic background, a much smaller number of cloned monkeys carrying disease phenotypes may be sufficient for pre-clinical tests of the efficacy of therapeutics. (inverse.com)
This was how Chinese scientists in Shanghai recently managed to clone macaque monkeys 3 - the first cloning of primates. (chemistryworld.com)

In 2005, they published again in Science the successful cloning of 11 person-specific stem cells using 185 human eggs. (wikipedia.org)
The revelation has destroyed the best evidence so far that stem cells can be extracted from a clone matched to a specific patient. (nature.com)
If healthy stem cells can be cloned, they can ― potentially ― be used to treat a wide range of conditions using replacement therapy. (koreatimes.co.kr)

2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
Agreeing with the premise of an earlier article in the same journal, he agrees that we "must not let our debate get completely derailed by vested interests, whether politically or economically motivated", and that the failure to find global agreement on human cloning at the U.N. could result in "reproductive" human cloning [and all the abuses of women that would entail]. (lifeissues.net)

In 2004, Hwang announced the first complete cloning of human embryo. (wikipedia.org)
Hwang Woo-suk became the first researcher in the world to clone a dog, an Afghan hound named Snuppy, in 2005. (koreatimes.co.kr)

He rose to public notice in 1999 when he announced that he had successfully cloned a dairy cow, named Yeongrong-i, and a few months later, a Korean cow, Jin-i (also reported as Yin-i). (wikipedia.org)
Five clones of a gene-edited long-tailed macaque with several symptoms of genetic disease have been successfully bred, announced a team of scientists in Shanghai this week. (inverse.com)
Exactly one year ago, the same researchers announced that they'd successfully cloned two macaques , named Hua Hua and Zhong Zhong. (inverse.com)

One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)

Adding on top of that the successful cloning of primates with CRISPR-mediated gene deletions, the researchers have gone to great lengths to study the biological mechanisms for genetic diseases. (inverse.com)

For its potential medical value to replace diseased and damaged cells, several scientists have tried to clone the human embryo, but in vain. (wikipedia.org)
As such, monkey cloning may be limited to medical research, where having more than one monkey with the same genes could help scientists compare the results of treatments or test under specific conditions. (engadget.com)
In the middle of the year 2001 a group of scientists said cloning humans might be easier than cloning animals. (irfi.org)
Many scientists were dismayed and scientists involved in animal cloning warned of the many practical problems in cloning. (irfi.org)
In the light of this information, Congress could settle for less stringent restrictions on embryo cloning studies, which scientists favor. (irfi.org)
The newly discovered obstacle makes it more likely than ever that rogue scientists' recent claims to have created cloned babies were fraud. (irfi.org)
The original monkey had been altered with CRISPR/Cas9 gene editing technology to give its clones a disrupted circadian rhythm so that scientists can learn how to treat humans with related disorders. (inverse.com)
That month, scientists reported the first successful attempt to reproduce a large, adult mammal through cloning. (exposingsatanism.org)

A clone is an animal that developed from an egg produced from the nuclear DNA from non-germ cells of a single sexually mature adult. (ideosphere.com)

2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
While eggs chemically triggered to develop don't have what it takes to make a viable embryo, it's a different story if the egg has been given the chromosomes of a cell from a more mature organism, through the technique of somatic-cell nuclear transfer used in cloning. (chemistryworld.com)

The following UGDH gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). (genscript.com)

Hwang's early work was with pigs and cows, though his cloning experiments in this field, while gaining him some visibility within Korea, were not backed up by internationally credible data. (koreatimes.co.kr)

An Italian fertility doctor, Dr. Severino Antinori announced his intention to clone humans, so that he can help infertile couples to have children. (irfi.org)
I hope that this will not be used to give encouragement to those who wish to clone humans,' he said. (irfi.org)
You can't say, taking this information in isolation, that it's easier to clone primates and humans,' he said. (irfi.org)
Church argued that a potential benefit to humans of such Neanderthal cloning would be increased genetic diversity. (medpagetoday.com)
Review of Critical Article: Cobbe, 'Why the apparent haste to clone humans? (lifeissues.net)
See Neville Cobbe, "Why the apparent haste to clone humans? (lifeissues.net)

it cannot work properly, and so the cloned embryo grows in an uncontrolled way. (irfi.org)
Dr John Parrington, a cloning expert at University College London, pointed out that more than one gene behaved in a way that might cause problems in a growing cloned human embryo. (irfi.org)
On April 11, 2003, Washington Post Staff Writer, Rick Weiss, reported 'New research suggests that it may be a lot harder to clone people than to clone other animals, an unexpected scientific twist that could influence the escalating congressional debate over human cloning and embryo research. (irfi.org)
But opponents of human embryo research were afraid that the new research not only identifies previously unrecognized hurdles to human cloning, but also points the way to overcoming those hurdles. (irfi.org)

For example many clones die early or they are born with genetic deformities, and develop terminal illnesses such as cancer. (irfi.org)
A clone is an organism that is a genetic copy of an existing one. (who.int)

Research ethics and lessons from Hwanggate: what can we learn from the Korean cloning fraud? (bmj.com)

Assuming the cloning of a Neanderthal to be possible, the decision to clone raises distinct ethical concerns. (medpagetoday.com)
Finally, any ethical assessment of Neanderthal cloning must consider the welfare of the individual being cloned. (medpagetoday.com)

A live birth of a primate clone will occur by January 1, 2000 and be reported within 6 months. (ideosphere.com)

Do our only cloned primates come from the lab of Woo Suk Hwang's colleague? (nature.com)
It was groundbreaking stuff because prior to Hwang's announcement, it was widely believed that this procedure was impossible due to the complexity of primates' cellular structures. (koreatimes.co.kr)

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. (genscript.com)

After years of experiments …cloning hit the big time in February 1997. (exposingsatanism.org)

WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)

Still, it reflects progress in cloning science. (engadget.com)
This report is bad news for the unethical charlatans who have been preying on people by claiming they are able to clone people's loved ones,' said Gerald Schatten of the University of Pittsburgh School of Medicine, who led the new study in April 11, 2003 issue of the journal Science. (irfi.org)
Cloning is as much an art as it is a science," said Robert Lanza of Advanced Cell Technology in Worcester, Massachusetts. (exposingsatanism.org)

In the paper, they explain that the ability to produce gene-edited clones will help them study diseases related to disrupted circadian rhythm , including Alzheimer's disease, depression, and other sleep problems. (inverse.com)

Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
It remains a big problem for the cloning technology," an anonymous Shanghai-based life scientist who was not involved in the story told South China Morning Post . (inverse.com)

There could be success with cloning based on adults, too, as the team is still waiting on results from multiple pregnancies. (engadget.com)

As Amber Tong reported for Endpoints News at the time, the challenges of cloning primates made this achievement a momentous one. (inverse.com)

Bringing an advanced Homo sapien-like primate into the world merely to satisfy our own intellectual curiosity seems problematic. (medpagetoday.com)

As animals akin to other primates? (medpagetoday.com)

Whether or not you mind cloning based on fetuses, the process currently requires many failures to get to the intended results. (engadget.com)

Qualifying reports " are articles in the print editions of the named newspapers that say a clone of a primate took place, and which appear to be reporting on the same event. (ideosphere.com)

There's also the question of what happens with those clones that do survive into adulthood -- they may face pressure to live up to the original. (engadget.com)

And he also agrees that if we don't find global agreement on human cloning, "we can probably expect dire consequences for the future of biomedical research and its impact on society at large. (lifeissues.net)

One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence. (genscript.com)

Retrieved on December 04, 2023 from https://www.news-medical.net/life-sciences/Cloning-Human-Cells.aspx. (news-medical.net)

The following year, he announced the preparation for cloning an endangered Siberian tiger. (wikipedia.org)

The prospect of cloning human beings remains both scientifically challenging and, for many, ethically fraught. (medpagetoday.com)

Harvard geneticist George Church, PhD, has explained that once such DNA is reassembled inside a human cell, either a chimpanzee or an "extremely adventurous female human" might bring the clone to term. (medpagetoday.com)

Anatomy26

Organisms66

Diseases6

Chemicals and Drugs42

Analytical, Diagnostic and Therapeutic Techniques and Equipment38

Psychiatry and Psychology3

Phenomena and Processes80

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Information Science4

Health Care1

Embryos9

Dolly8

Therapeutic7

Somatic cells1

Embryonic7

Monkeys8

Stem cells3

Reproductive5

Hwang2

Successfully3

SCNT2

Researchers1

Scientists8

Adult1

Nuclear transfer2

CDNA ORF clone1

Pigs1

Humans6

Embryo4

Genetic2

Fraud1

Ethical2

Occur1

Hwang's2

Rhesus1

Experiments1

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Science3

Gene1

Technology2

Team1

Time1

Satisfy1

Animals1

Process1

Place1

Live1

Large1

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Female1