Primary prostate adenocarcinoma metastasis adenocarcinoma. Medical search. Frequent questions

Metastasis is one of the hallmarks of cancer, distinguishing it from benign tumors. (wikipedia.org)
The lungs, liver, brain, and bones are the most common metastasis locations from solid tumors. (wikipedia.org)
Multiple, large autopsy series suggest that, in order of decreasing frequency, lung (40%), breast (20%), melanoma (10%), and enteric cancers (6%) are the most common primary tumors to metastasize to the brain. (medscape.com)
Cancer spreading to the bones from elsewhere is much more common than cancer that begins in the bones (primary bone tumors). (massgeneral.org)
The most common kinds of metastatic bone tumors of the skeleton begin with prostate, breast, thyroid, lung, or kidney cancer. (massgeneral.org)
Metastatic tumors from the kidney or thyroid are usually very vascular (made of blood vessels) whereas tumors from prostate, breast and lung are less so. (massgeneral.org)
Most prostate cancers are multifocal, with synchronous involvement of multiple zones of the prostate, which may be due to clonal and nonclonal tumors. (medscape.com)
As they reported in Cell on Thursday, the researchers analyzed targeted panel sequence data for 15,632 primary and 10,143 metastatic tumors from a total of 25,755 metastatic cancer patients in the MSK-MET cohort, including patients who had matched primary and metastatic tumor samples sequenced. (genomeweb.com)
In contrast to prior studies that centered on either primary or metastatic tumors as a group, the team set out to characterize integrated genomic and clinical features of metastatic disease in the context of cancer type and anatomic site of metastasis. (genomeweb.com)
Together with molecular data across 341 to 468 cancer genes profiled with the MSK-IMPACT clinical sequencing assay , these insights made it possible to compare molecular features found in tumors from primary or metastatic sites in individuals with or without metastases. (genomeweb.com)
Lung and breast tumors are the most common primary malignancies to affect the skull. (medscape.com)
Those metastases can be further classified according to their extension toward the subdural or extradural space and can frequently simulate other pathologic conditions including chronic subdural hematomas, abscess, and primary bone tumors. (uniba.it)
Background/Aim: Intradural cauda equina metastases (ICEM) are rare tumors that reduce functional status. (iiarjournals.org)
Neoplastic CES may arise from cauda equina primary tumors or secondary metastases, which may involve the vertebral bones, resulting in fracture and external nerve compression ( 5 ). (iiarjournals.org)
No staging system exists for cancers of unknown primary origin-more precisely, histologically proven metastatic malignant tumors for which the primary site cannot be identified during pretreatment evaluation. (medscape.com)
These tumors do not have androgen receptors to unlike prostate adenocarcinomas. (uroonkolojibulteni.com)
Metastases to the umbilicus is mostly from gastrointestinal tract or genitourinary tract tumors and they are usually adenocarcinomas. (irispublishers.com)
Primary cardiac tumors are rare, with an incidence in early autopsy series from 0.001% to 0.3% [ 1 , 2 ]. (journalmc.org)
The majority of these are benign, primary malignant heart tumors accounting for less than 25% [ 3 ]. (journalmc.org)
Most cardiac tumors are metastatic and 20 - 40 times more common than primary tumors [ 4 , 8 ]. (journalmc.org)
Glioblastoma multiforme (GBM) is a highly aggressive and heterogeneous form of primary brain tumors, driven by a complex repertoire of oncogenic alterations, including the constitutively active epidermal growth factor receptor (EGFRvIII). (cancer-genetics.org)
Moreover, there was a significant decrease in the expression of R-I and R-II mRNA, in all 20 primary prostatic tumors and 4 lymph nodes positive for metastases, indicating that the decreased protein expression was due to down-regulation of gene expression for the two receptors. (nih.gov)
Primary tumors with higher PSMA uptake and SUV have been shown to be associated with higher serum PSA levels and a higher Gleason score. (siemens-healthineers.com)
We identified 18 publicly available gene expression datasets in the Oncomine database comparing distant metastases to primary tumors in various solid tumors which met our eligibility criteria. (biomedcentral.com)
We have modified a previously published meta-analysis method and identified a common metastatic signature by comparing primary tumors versus metastases in various tumor types. (biomedcentral.com)
Metastasis of infradiaphragmatic tumors to the left supraclavicular lymph node is reported to be rare. (biomedcentral.com)
Supraclavicular lymph node metastasis has been reported to be more common in patients with lung and breast tumors (18.7% and 18.6%, respectively) [ 1 , 2 ]. (biomedcentral.com)
In addition, metastatic sites may re-seed primary tumors in a multi-directional fashion [ 8 ]. (oncotarget.com)

We present a case of penile metastases in a 74-year-old male patient with prostatic adenocarcinoma in association with multiple skeletal metastases. (manipal.edu)
The index case is being presented for its rarity and probable poor outcome in young patients and to stress on the fact that the possibility of primary prostatic adenocarcinoma should be investigated in a male presenting with bone metastasis irrespective of the age. (jpalliativecare.com)
Histology confirmed the presence of metastatic moderately well differentiated prostatic adenocarcinoma (Figure 1 ) extending through the length of the penis and into the glans and spreading to the surface of the skin at the corona with vascular and lymphatic permeation. (biomedcentral.com)
We report a sporadic case of an 84-year-old man with a pacemaker diagnosed with heart osteosarcoma, hepatocellular and prostatic adenocarcinoma and presenting with symptoms mimicking infective endocarditis. (journalmc.org)

The researchers also found associations between primary cancer subtypes and the body sites that were later impacted by metastatic disease, including an overrepresentation in liver metastases among patients with metastatic forms of lung neuroendocrine cancer and an uptick in ovarian or peritoneum metastases in individuals with advanced lobular breast cancer. (genomeweb.com)
Machine Learning Models for Predicting the Outcomes of Surgical Treatment of Colorectal Liver Metastases. (cdc.gov)

Prostate-specific antigen (PSA)-levels, changes in PSMA-uptake of MLN metastases and further 68 Ga-PSMA PET/CT findings were recorded. (frontiersin.org)
The Type-II transmembrane protein prostate specific membrane antigen (PSMA) is overexpressed in almost all PCa cells ( 6 ). (frontiersin.org)
There was only a slight decrease in prostate-specific antigen (PSA) level and pelvic disease post treatment. (jpalliativecare.com)
In prostate cancer, whole-body PET determinations of prostate-specific membrane antigen (PSMA) expression are now established, approved, and available for disease staging and restaging. (snmjournals.org)
The use of serum prostate-specific antigen (PSA) levels has been recognised as a huge step forward in the diagnosis and treatment of prostate cancer, however since its implementation as a biomarker it has become apparent that the numbers of deaths from prostate cancer has only decreased slightly. (almacgroup.com)
There was an elevated prostate-specific antigen (PSA) level in the patient. (uroonkolojibulteni.com)
Participants will undergo regular testing for signs of disease progression using computed tomography (CT) scans, magnetic resonance imaging (MRI), bone scans, and prostate-specific antigen (PSA) blood tests. (uclahealth.org)
Prostate-specific antigen levels and magnetic resonance imaging findings aided the diagnostic process. (biomedcentral.com)
In Sweden, there has been a steady prostate-specific antigen (PSA) velocity for the diagnosis of pros- decrease in age-standardized breast cancer mortality in women up tate cancer (15). (lu.se)
There has been a downward "age migration" in the PSA (prostate-specific antigen) era such that the median age of diagnosis is now approximately 60 years old. (science-medic.com)

However, brain MRI for patients with primary cancers that frequently metastasize to the brain (eg, bronchogenic carcinoma) is probably cost-effective. (medscape.com)
Most prostate cancers are adenocarcinomas. (medscape.com)
These cancers were also less likely to show metastases-associated chromosomal stability. (genomeweb.com)
Metastasis is one of the hallmarks of cancer , distinguishing it from benign tumor s. [7] Most cancers can metastasize, although in varying degrees. (explained.today)
Therefore the identification of new biomarkers and treatments for highly invasive/metastatic prostate cancers is of a high priority. (almacgroup.com)
Subtype of small cell carcinoma of the prostate constitute about 0.5-2% of all prostate cancers. (uroonkolojibulteni.com)
Each year, more people die of lung cancer than of colon, breast, and prostate cancers combined. (hindawi.com)
More than 32 genes that are important in suppressing the development of metastasis in one or more human cancers have been identified to date [ 4 ]. (biomedcentral.com)
Patients with oral squamous cell carcinoma and those with other types of head and neck cancer are at higher risk of second primary cancer than patients with cancers at most other sites [ 3 ]. (biomedcentral.com)
Risk increases with age, but, unlike other cancers, prostate cancer has no "peak" age or modal distribution. (science-medic.com)

Pure small cell carcinoma of the prostate (SCPCa) is a very rare condition usually with poor survival after diagnosis. (karger.com)
Carcinoma of the prostate metastasising to the penis is rare. (biomedcentral.com)
Primary urethral carcinoma (PUC) has a low incidence, but with high aggressiveness. (bvsalud.org)
In conclusion, in patients with positive PD-1 ligand 1 expression in primary female urethral squamous cell carcinoma, chemotherapy combined with PD-1 inhibitors may be effective. (bvsalud.org)
INTRODUCTION: The treatment landscape in invasive primary carcinoma of the urethra of urothelial histology closely aligns that of locally advanced urothelial carcinoma of the bladder. (bvsalud.org)
The survival benefit of perioperative chemotherapy for men undergoing radical surgery for primary urethral urothelial carcinoma (UUC) has not yet been well-elucidated. (bvsalud.org)
Results: A total of 19 patients were included, but only 3 were diagnosed with small cell prostate carcinoma, while the majority had a primary prostate adenocarcinoma. (uniba.it)
One third of patients with cancer of unknown primary origin have poorly or undifferentiated carcinoma. (medscape.com)
Small cell carcinoma of the prostate is a rare and highly aggressive subtype. (uroonkolojibulteni.com)
Most common type of small cell carcinoma of the prostate is neuroendocrine differentiation type which is associated with prostate adenocarcinomas. (uroonkolojibulteni.com)
As a result of the biopsy, small cell carcinoma of the prostate which was present in acinar adenocarcinoma component (30-40%) was detected. (uroonkolojibulteni.com)
Adenocarcinoma bladder A tumour that may be primary and result from differentiation of a urothelial carcinoma. (malaimare.ro)
Rare carcinoma that resembles benign hyperplastic glands Difficult to grade Epstein recommends deferring to the grade of papillary urothelial hyperplasia bladder associated usual type adenocarcinoma in the radical prostatectomy specimen, which is often Gleason score 5- 7. (malaimare.ro)
There are three main subtypes of NSCLC which are adenocarcinoma (~40% of cases), squamous cell carcinoma (~25-30% of cases), and large-cell carcinoma (~10-15% of cases). (hindawi.com)
When metastasis is detected in the left supraclavicular node in patients with head and neck carcinoma, locating the primary cancer remains a difficult and time-consuming challenge despite the dramatic development of screening technologies and treatment methods. (biomedcentral.com)
We report three cases of malignant infradiaphragmatic tumor diagnosed following an initial finding of left supraclavicular node metastasis after surgery for tongue squamous cell carcinoma (follow-up period, range 18-62 months). (biomedcentral.com)
In these cases, adenocarcinoma was diagnosed based on left supraclavicular node biopsies, and a second primary tumor was found, in a 78-year-old Japanese woman with a diagnosis of cholangiocarcinoma, a 64-year-old Japanese man with a diagnosis of bladder carcinoma, and a 61-year-old Japanese man with a diagnosis of prostate carcinoma. (biomedcentral.com)
Hematoxylin-eosin staining of the bladder lesion did not identify a clear glandular or squamous component, and we could not make a definitive diagnosis of whether the lesion was poorly differentiated squamous cell carcinoma, adenocarcinoma, or high-grade urothelial carcinoma. (biomedcentral.com)
In the prostate carcinoma case, 18 F‐fluorodeoxyglucose uptake was weak. (biomedcentral.com)
In contrast, second primary cancer at other sites, such as the intrahepatic bile duct, bladder, and prostate, is rare in patients with tongue carcinoma. (biomedcentral.com)
Pathology result of the surgical specimen revealed poorly differentiated prostate carcinoma with positive surgical margins. (doctorsmedicalopinion.com)

Twelve PCa patients with biochemical recurrence (BCR) after primary therapy who prospectively underwent a baseline 68 Ga-PSMA-PET/CT initially showed MLN metastases. (frontiersin.org)
Nonetheless, within 10 years after primary therapy up to 40% of patients develop biochemical recurrence (BCR) ( 3 ). (frontiersin.org)
No recurrence or distant metastasis was found after 20 months of follow-up. (bvsalud.org)
On the other hand, a significant number of patients with early-stage disease develop both localised recurrence and distant metastases ( 2 ). (spandidos-publications.com)
This predict the likelihood of a later recurrence, i.e., an indicator that unique longitudinal sample material was collected from each pa- allows risk assessment for breast cancer metastasis, would be tient between 0 and 36 mo after the primary operation. (lu.se)
How- recurrence after primary operation could be assessed for each pa- ever, recent developments in affinity proteomics have advanced tient, using her molecular portraits. (lu.se)

Bone metastases, or bone mets, occur when cancer cells from a primary tumor spread to the bone. (massgeneral.org)
Bone metastases can cause a wide range of symptoms that could impair quality of life of lung cancer patients and shorten their survival. (hindawi.com)
We strongly believe that molecular targets (tumor-related and bone microenvironment based) that have been implicated in lung cancer bone metastases hold great promise in lung cancer therapeutics. (hindawi.com)
Although there are currently some available palliative treatment options for patients with bone metastases from any solid tumor origin such as radiation therapy and bone targeted/bone strengthening treatments (bisphosphonates and denosumab) that are used in clinical practice, none of them is specific for lung cancer metastases and they do not affect the poor survival outcome of this disease. (hindawi.com)
We believe that these molecular targets could guide in determining timing of therapeutic interventions that offer the best opportunity to prevent and/or halt extent of bone metastases. (hindawi.com)
Thus, in this report, we will assess the data on lung cancer bone metastases with the intention of evaluating key molecular targets that could be applied in optimizing lung cancer treatment strategies. (hindawi.com)
A Multidisciplinary Bone Metastases Clinic at Toronto Sunnybrook Regional Cancer Centre. (scirp.org)
Bone Metastases of Prostate Cancer: Contribution of Specific Determination of Bone Alkaline Phosphatase," Immuno-Analyse & Biologie Specialisee, Vol. 10, 1995, pp. 27-33. (scirp.org)

B: Tumor- genital hpv definition tumor metastasis to a thyroid follicular adenoma. (malaimare.ro)
It is widely accepted that tumor metastasis is a formidable barrier to effective treatment of lung cancer. (hindawi.com)

Brain metastases are an increasingly important cause of morbidity and mortality among cancer patients. (medscape.com)
The prognosis for patients with brain metastases is typically poor. (medscape.com)

In fact, over two-thirds of lung cancer patients have regional lymph-node involvement or distant metastases at the time of presentation [ 3 ]. (hindawi.com)
The 68 Ga PSMA PET/CT was instrumental in accurately staging this patient who was otherwise clinically considered free of nodal or distant metastases. (siemens-healthineers.com)

Squamous cell carcinomas are rare, constituting less than 1% of all prostate carcinomas. (medscape.com)
In many cases, prostate carcinomas with squamous differentiation arise after radiation or hormone treatment. (medscape.com)
In particular, an increase in chromosomal instability turned up in metastatic forms of lung or prostate adenocarcinomas and in hormone receptor- and HER2-positive breast carcinomas originating in the duct, the researchers reported. (genomeweb.com)
Primary female urethral carcinomas are uncommon and have a low morbidity rate. (bvsalud.org)
Background: Prostate carcinomas rarely metastasize to the central nervous system but, when they do, dural localizations are as common as and far more aggressive than intraparenchymal ones. (uniba.it)
Cases of small cell carcinomas of the prostate are highly metastasis at diagnosis. (uroonkolojibulteni.com)
The prognosis of small cell carcinomas of the prostate is very poor, unlike adenocarcinoma. (uroonkolojibulteni.com)

Our investigation describes MLN metastases as index lesion in 68 Ga-PSMA PET/CT imaging for recurrent PCa. (frontiersin.org)
MLN metastases detected by 68 Ga-PSMA-PET/CT seem to be a relevant localization of tumor manifestation and may serve as index lesion in the treatment of recurrent PCa. (frontiersin.org)
Most patients with bony metastases present with pain in the area of the lesion with decreased mobility and motion. (massgeneral.org)
The radiologist plays a primary role in the management of cancer patients by helping detect, localize, and diagnose the lesion. (medscape.com)
Approximately one third of patients operated on for a single cerebral metastasis diagnosed with contrast-enhanced CT probably have more than one lesion. (medscape.com)
Biopsy of the lesion showed poorly differentiated adenocarcinoma with sarcomatoid features. (appliedradiationoncology.com)
The 6 mm solitary pelvic nodal metastasis had a SUV max of 5.8 with high lesion-to-background ratio seen on the PET images, which helped differentiate the lesion from surrounding uptake in the ureter and intestines. (siemens-healthineers.com)
High ToF performance on Biograph Vision demonstrates a possible key relevance for such sharp delineation of a 6 mm lymph node metastasis with high lesion-to-background ratio. (siemens-healthineers.com)
Increased contrast to background in any nodal lesion helps distinguish a metastasis from adjacent soft tissue and physiological uptake in the intestines. (siemens-healthineers.com)
The anatomo-pathological evidence was made after biopsy of the bone lesion or primary cancer. (scirp.org)

Cancer patients now live longer as a result of important advances in cancer diagnosis and management-particularly, the widespread use of magnetic resonance imaging (MRI) to detect small metastases. (medscape.com)
Early diagnosis and aggressive treatment of brain metastasis may result in remission of brain symptoms and may enhance the quality of the patient's life while prolonging survival. (medscape.com)
A clinical diagnosis of penile metastases was made. (biomedcentral.com)
Median time from primary tumor diagnosis to ICEMs' presentation was 36 months. (iiarjournals.org)
Palliative care only was given, with survival for 11 months after diagnosis of lymph node metastasis. (biomedcentral.com)
GATA3 staining aided in the diagnosis of urothelial bladder cancer with left supraclavicular node metastasis. (biomedcentral.com)
He survived for 2 months after diagnosis of left supraclavicular lymph node metastasis. (biomedcentral.com)
This patient underwent bilateral orchiectomy and adjuvant hormonal therapy and survived for 47 months after diagnosis of left supraclavicular node metastasis. (biomedcentral.com)
The diagnosis of bone metastasis was made because of the existence of bone pain, or pathological fracture, or bone swelling and a bone-condensing or mixed or osteolytic radiological image. (scirp.org)

Age, hereditary factors, nutrition, and certain environmental factors are primary risks of developing prostate cancer. (medscape.com)
Age The risk of developing prostate cancer begins to increase at age 50 years in white men who have no family history of the disease and at age 40 years in black men and those who have a first-degree relative (father, brother) with prostate cancer. (science-medic.com)
Family history Men who have a first-degree relative with prostate cancer have approximately a twofold increased risk of developing prostate cancer during their lifetime. (science-medic.com)

Likewise, the highest concentrations of this oncoprotein are found in patients with breast cancer, but lower concentrations may be found in other malignancies, particularly ovarian, prostate and lung cancer (mainly adenocarcinomas). (degruyter.com)
Thus, this paper discusses some of the emerging molecular targets that have provided insights into the cascade of metastases in lung cancer with the focus on bone invasion. (hindawi.com)
Involvement of bone in lung cancer metastases is a major source of morbidity and mortality arising from skeletal related events (SREs) [ 10 ]. (hindawi.com)
Bone metastasis is a major determinant of treatment outcome, quality of life, and survival for lung cancer patients [ 12 - 14 ]. (hindawi.com)
This underscores the need to assess molecular targets that can be exploited in prevention or clinical management of lung cancer metastases to bone. (hindawi.com)
However, these same studies do not re- port an increased risk of dying from prostate cancer associated with vasectomy but do in- dicate a statistically increased risk of dying ejaculation frequency (greaterthan 21 ejaculations per month) from lung cancer. (science-medic.com)

With many patients, the primary tumor is not identified, so staging studies and biopsy are necessary to rule out a primary malignant bone tumor. (massgeneral.org)
Biopsy of these nodules showed several malignant glandular structures infiltrating the corpus cavernosa of the penis suggestive of a poorly differentiated adenocarcinoma, confirmed immunohistologically (Figure 2 ) as of prostatic origin. (biomedcentral.com)
A biopsy is obtained and confirms adenocarcinoma of the prostate. (osmosis.org)
Therefore, transrectal prostate biopsy was performed. (uroonkolojibulteni.com)
The optimal threshold torecommend prostate biopsy has Prostate cancer screening with PSA and digi- tal rectal examination (DRE) has resulted in not only an increase in prostate cancer detec- tion but also a stage shift. (science-medic.com)

[ 3 ] The radiologist plays a primary role in management of cancer by providing accurate information on number, size, and locations of metastatic lesions, which is crucial for selecting the most appropriate treatment method for patients. (medscape.com)
Lesions with low PSMA expression and high glycolytic activity (PSMA-negative/ 18 F-FDG-positive) can occur in up to 30% of metastatic castration-resistant prostate cancer patients referred for PSMA-targeted MRT ( 14 , 15 ). (snmjournals.org)
Methods: A series of consecutive patients admitted during a 12-year period through our oncall pathway for subdural/extradural collections or intraparenchymal lesions found, on histologic analysis, to represent intracranial prostate cancer metastases was retrospectively reviewed. (uniba.it)
Metastases could be classified as pure subdural space lesions, dural-based lesions, extradural/bony lesions, and pure intraparenchymal lesions. (uniba.it)
All patients with subdural metastases and 3 out of 5 patients with dural-based lesions required an emergency intervention due to rapidly deteriorating neurologic status. (uniba.it)
The study of precancerous lesions of the prostate is important for understanding prostatic carcinogenesis and for developing potential. (malaimare.ro)
Excellent ToF performance, high resolution, and count-rate capability available with Biograph Vision should have a positive impact in improving the accuracy of staging since the detectability of small metastatic lesions is a key driver in the staging of prostate cancer. (siemens-healthineers.com)
A common metastatic signature of 79 genes was identified in the metastatic lesions compared with primaries with a False Discovery Proportion of less than 0.1. (biomedcentral.com)

His beta-hCG subsequently improved to 2031, but a follow-up PET-CT after the cycle showed progressive worsening of his pulmonary metastases. (appliedradiationoncology.com)

Penile metastases are rare in occurrence and are usually secondary to other genitourinary primary tumours. (manipal.edu)
The usual points of obstruction are bladder neck, prostate, perineal urethra, penile urethra and os penis. (vin.com)

After bilateral inguinal orchidectomy, he was started on anti-androgen therapy and received palliative radiotherapy for bone metastasis. (jpalliativecare.com)
The VISION trial showed that PSMA-targeted molecular radiotherapy (MRT) can prolong survival and improve quality of life of patients with advanced metastatic castration-resistant prostate cancer ( 1 ). (snmjournals.org)
Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)

It seems to show different clinical features compared to other prostate cancer subtypes, specifically adenocarcinoma. (karger.com)
The latest clinical study (SELECT trial) tested AT in prostate cancer patients, determined that AT provided no benefit, and could promote cancer. (biomedcentral.com)
Primary and metastatic cardiac sarcomas represent rare neoplasms with a variable clinical course. (journalmc.org)
The 68 Ga PSMA PET/CT was instrumental in detecting a solitary pelvic lymph node metastasis in this patient with primary prostate cancer who otherwise had no clinical or radiological suspicion of metastases. (siemens-healthineers.com)
ARL9 is a newly identified member of the ARF family, and the clinical significance of ARL9 in colon adenocarcinoma is unknown. (biomedcentral.com)
Clinical, Genetic and Environmental Determinants of Prostate Cancer Progression. (who.int)

It may arise in a polyp or from urachal remnant tumours and resemble colorectal tumours, or it can be the recipient of prostate or colorectal metastases. (malaimare.ro)
Among them, colorectal adenocarcinoma is the main histological subtype of colorectal cancer. (biomedcentral.com)

The incidence of brain metastasis is rising with the increase in survival of cancer patients. (medscape.com)
In Europe the most common cancer in male is prostate cancer (PCa) with growing incidence in the past two decades ( 1 ). (frontiersin.org)
reported that the risk of a second primary oral cancer was higher (standardized incidence ratio 16.25, 95% confidence interval 13.04-20.02) than that of nonoral second primary cancer (standardized incidence ratio 1.37, 95% confidence interval 1.29-1.45) in Korean patients with cancer in the oral cavity [ 4 ]. (biomedcentral.com)
Race The highest incidence of prostate cancer in the world is found in Ameri- can black men, who have approximately a 9.8% lifetime risk of developing this cancer. (science-medic.com)
Black men have an incidence of prostate cancer that is 1.6 times that of whites. (science-medic.com)
Interestingly, although Japanese immigrants to the United Stateshave a higher incidence of prostate cancer than Japanese people living in Ja-pan, their rate is still about half that of American whites. (science-medic.com)
Geography The incidence of prostate cancer is highest in Scandinavian coun- tries (22 cases per 100,000 population) and lowest in Asia (5 per 100,000). (science-medic.com)
However, no definitive proof of its role their history of ejaculationfrequency by filling out serial Vasectomy Several large epidemiologic stud- ies suggest that vasectomy may increase the relative risk of prostate cancer by as much as incidence of prostate cancer inthe group. (science-medic.com)

The highest levels may be seen in metastatic breast cancer, particularly with metastases to the liver or the bones. (medscape.com)

Prostate cancer is the most common malignancy in males, accounting for 19% of new cancer cases in males and 29,430 deaths in 2018 [ 1 ]. (biomedcentral.com)
In spite of the advances in treatment of primary malignancy, cases of relapse and metastatic spread have created major hurdles to reaching the desired treatment outcome [ 7 ]. (hindawi.com)

Brain metastasis affects up to one third of adults with cancer and carries a historically bleak prognosis. (medscape.com)
Beside the challenges of the preoperative differential diagnostic and complexity of surgical planning and operative excision, subdural metastases seem to carry a much poorer prognosis. (uniba.it)
The prognosis is dependent on the stage of the disease and extent of metastases. (hindawi.com)
In this study, we aimed to explore the expression of ARL9 mRNA in colon adenocarcinoma, and its effect on the prognosis of patients with colon adenocarcinoma. (biomedcentral.com)
Age and the high mRNA expression of ARL9 were independent risk factors for a poor prognosis in patients with colon adenocarcinoma. (biomedcentral.com)
The mRNA expression of ARL9 is upregulated in colon adenocarcinoma, and higher mRNA expression levels are associated with a poor prognosis. (biomedcentral.com)
The influence of cardiovascular morbidity on the prognosis in prostate cancer. (urotoday.com)

For example, in pancreatic as well as in prostate cancer, it papillary urothelial hyperplasia bladder been found that SHh is. (malaimare.ro)

Metastasis to the brain is the most feared complication of systemic cancer and the most common intracranial tumor in adults. (medscape.com)
With regard to screening for intracranial metastases, no consensus has been reached concerning when CT or MRI should be used for initial staging evaluation of a patient with cancer. (medscape.com)
Surgery may be required for patients presenting with a solitary intracranial tumor or to search for a possible primary tumor. (medscape.com)

A 69-year-old man presented to his primary care physician in December 2016 for evaluation of bilateral tender gynecomastia without any history of breast mass or injury. (appliedradiationoncology.com)
Advanced disease Rarely, men with bulky lymph node metastasis may pre- sent with bilateral lower extremity edema. (science-medic.com)

A subset of neoplastic CES, intradural cauda equina metastases (ICEM), represent a rare but challenging entity ( 6 , 7 ). (iiarjournals.org)
The spine is the most frequent area of bone metastasis in patients with systemic neoplastic disease. (bvsalud.org)

Histologic reports of beta-hCG producing Barrett's adenocarcinomas of the esophagus have been reported, 2 as well as gonadotropin-producing adenocarcinomas of the pancreas, stomach and prostate. (appliedradiationoncology.com)
The histologic subtype, metastasis site, and certain patient characteristics can offer clues to the cancer primary. (medscape.com)

I also have expertise in stereotactic body radiation therapy for the treatment of primary and metastatic gastrointestinal malignancies. (rochester.edu)

Approximately 95% of prostate neoplasms are adenocarcinomas. (uroonkolojibulteni.com)

Most patients with a known primary tumor undergo imaging studies when neurologic signs and symptoms develop. (medscape.com)
Besides the known oncological benefits of ADT and sRT, in case of sole MLN metastases individualized therapy like salvage lymphadenectomy or RT with a defined radiation field could be options for these patients. (frontiersin.org)
however showed PCa metastases in mesorectal lymph nodes (MLN) in 12 of 76 patients with BCR, which were detected by 68 Ga-PSMA PET/CT ( 11 ). (frontiersin.org)
Previous reports either described MLN metastases of PCa occurring in sentinel lymph node scintigraphy or as a random result during anterior rectal resection in patients with rectal cancer ( 16 - 19 ). (frontiersin.org)
Metastatic Adenocarcinoma of Prostate in a 28-Year-Old Male: The outcome is poor in young patients? (jpalliativecare.com)
Prostate cancer is common in older patients. (jpalliativecare.com)
Most of the published data has reported poor outcome in younger patients with metastatic prostate cancer. (jpalliativecare.com)
With insights from more than 99,400 metastatic events identified in 21,546 metastatic cancer patients, they flagged genomic patterns corresponding to metastases from dozens of cancer types that affected 21 different organs, along with suspicious primary tumor changes in individuals with metastatic disease. (genomeweb.com)
Using electronic health record data, the researchers searched for patients with metastatic disease and information about the timing of metastasis. (genomeweb.com)
Of 75 patients, metastases was restricted to the corpora cavernosa in 32 patients, glans penis in 12, urethra in four, skin/prepuce in four and corpus spongiosum in three and 20 having multiple involved areas. (biomedcentral.com)
Of particular relevance to imaging is the fact that for patients with a solitary brain metastasis who undergo treatment by surgical resection, the survival rate after 1 year is approximately doubled. (medscape.com)
Blastic metastases are seen in patients with primary prostate cancer or in patients who have undergone treatment for breast cancer. (medscape.com)
Conclusions: Supported by our experience and the review of the literature, we suggest that a low threshold for contrast-enhanced computed tomography/magnetic resonance imaging is advisable in case of suspicious subdural collection, even in an emergency setting, for patients with previous medical history of prostate cancer. (uniba.it)
HER-2/neu sensitivity (proportion of patients with abnormal values) in patients with metastasis is around 40%-45%, with a clear relationship to tissue overexpression and to site (higher in visceral metastases) and number of metastases. (degruyter.com)
3687 patients were hospitalized for active cancer, among them 81 had documented bone metastasis. (scirp.org)
75% of patients were more or equal to 50 years old at the discovery of the bone metastasis. (scirp.org)
ARL9 mRNA can be used as a prognostic biomarker in patients with colon adenocarcinoma. (biomedcentral.com)
However, a simple way to screened 240 sera from 64 patients with primary breast cancer. (lu.se)
The potential for improved outcome in patients with hepatic metastases from colon cancer: A population-based study. (cancercentrum.se)

The newly pathological sites, then, are metastases (mets). (wikipedia.org)

When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are similar to those in the original or primary tumor. (wikipedia.org)
They are classified essentially as primary (true, epithelial) and secondary (pseudo, non-epithelial) based on the presence. (annals.edu.sg)
Beyond single DTCs, death from bone metastasis may also be due to dissemination of disease via metastatic re-seeding from other secondary sites [ 7 , 8 ]. (oncotarget.com)
Examination of cells whether from a primary or secondary site, including fluids aspirated using endoscopes or needles. (who.int)

PSMA PET/CT of patient with metastatic castration-resistant prostate cancer before treatment with 177 Lu-PSMA therapy. (snmjournals.org)
The study will enroll participants with metastatic castration-resistant prostate cancer (mCRPC) previously treated with one prior androgen receptor axis-targeted therapy (ARAT). (uclahealth.org)
Received 1 prior ARAT for metastatic or non-metastatic, castration-sensitive or castration-resistant prostate cancer. (uclahealth.org)

F-18 fluorodeoxyglucose (FDG) demonstrated paratracheal and paraesophageal lymph node involvement, a 1.3-cm left lower lobe metastasis, and a right upper lobe metastasis too small to characterize ( Figure 1 ). (appliedradiationoncology.com)

Key outstanding questions revolve around the survival and migration of cancer cells, such as the nucleus, as they face challenges in passage through capillary valves and hydrodynamic shear forces in the circulation system, making CTCs an unlikely source of metastasis. (wikipedia.org)
Family History of Prostate Cancer and Survival Outcomes in the UK Genetic Prostate Cancer Study. (lu.se)
Certainly, the presence of bone metastasis usually leads to worse outcome and shorter median survival [ 11 , 15 , 16 ]. (hindawi.com)

The 68 Ga PSMA PET/CT (Figures 1-3) shows a solitary right external iliac lymph node metastasis along with the PSMA-avid primary prostatic tumor without evidence of any other skeletal, soft tissue, or extrapelvic nodal metastases. (siemens-healthineers.com)

Histology confirms the presence of invasive adenocarcinoma invading the corpora cavernosa (CC) (15×, H/E). (biomedcentral.com)

The rare cases that have neuroendocrine morphology are thought to arise from the neuroendocrine stem cells that are normally present in the prostate or from aberrant differentiation programs during cell transformation. (medscape.com)
Histologically confirmed adenocarcinoma of the prostate without evidence of neuroendocrine differentiation, signet cell, or small cell features. (uclahealth.org)

The effects of GT3 and AT were studied on androgen sensitive LNCaP and androgen independent PC-3 prostate cancer cells. (biomedcentral.com)

We report an unusual case of a gonadotropin-producing sarcomatoid adenocarcinoma of the esophagus that manifested as gynecomastia. (appliedradiationoncology.com)
Adenocarcinoma occurs in the distal esophagus. (msdmanuals.com)

A 66 year old man that was diagnosed with prostate cancer underwent radical prostatectomy 2 years ago. (doctorsmedicalopinion.com)

Almac sought to identify new biomarkers and drug targets by performing DNA microarray analysis of high Gleason score prostate tumour samples and normal prostate tissue samples. (almacgroup.com)
EOD-Extension--Small Intestine: How do we interpret a pathology description of "extending through serosa and forming masses in the periserosal tissue" for a jejunum primary? (cancer.gov)
We investigated the differential expression of ARL9 between colon adenocarcinoma tissue and adjacent tissues through a bioinformatics analysis using The Cancer Genome Atlas (TCGA) database. (biomedcentral.com)

To further these goals we developed a specific array platform, this array was based upon extensive sequencing of prostate tumour samples and contains approximately 90,000 probesets, many of which are specific to prostate cancer. (almacgroup.com)
Bone metastasis leads to approximately 280,000-350,000 cancer-related deaths in the United States each year [ 1 , 2 ]. (oncotarget.com)

These nodules are mostly adenocarcinomas with the commonest primary sites in intraabdominal organs. (irispublishers.com)

This uncontrolled proliferation by mitosis produces a primary heterogeneic tumour. (wikipedia.org)

Men with bony metastasis often present with bone pain and, uncommonly, with lower extremity weakness or paralysis from spinal cord compression. (science-medic.com)

A surgically proven, solitary right parietal metastasis is seen with a single, 1-cm, enhancing right parietal nodule and extensive surrounding edema typical of a metastasis. (medscape.com)

To determine whether, in this patient population, treatment with calcitriol and Naproxen is more effective in delaying the growth of prostate cancer than treatment with calcitriol alone as seen in historical controls. (stanford.edu)

Anatomy7

Organisms3

Diseases37

Chemicals and Drugs16

Analytical, Diagnostic and Therapeutic Techniques and Equipment26

Phenomena and Processes12

Disciplines and Occupations1

Information Science3

Health Care6

Tumors28

Prostatic adenocarcinoma4

Liver metastases2

Antigen10

Cancers10

Carcinoma21

Recurrence6

Bone metastases8

Tumor metastasis2

Brain metastases2

Distant2

Carcinomas7

Lesion10

Diagnosis9

Developing prostate cancer3

Lung cancer6

Biopsy5

Lesions8

Pulmonary metastases1

Penile2

Radiotherapy3

Clinical6

Colorectal2

Incidence8

Metastatic breast cancer1

Malignancy2

Prognosis7

Pancreatic1

Intracranial3

Bilateral2

Neoplastic2

Histologic2

Malignancies1

Neoplasms1

Patients19

Pathological1

Secondary4

Castration-resistant prostate3

Lymph node involvement1

Survival3

Skeletal1

Histology1

Neuroendocrine2

Androgen1

Esophagus2

Radical prostatectomy1

Tissue3

Approximately2

Nodules1

Tumour1

Bony1

Solitary1

Treatment1