Primary mucinous tumors endometrial neoplasms. Medical search. Frequent questions

Endometrioid tumors account for approximately 20% of all ovarian cancers and are mostly malignant (endometroid carcinomas). (wikipedia.org)
Histopathology revealed a uterine endometrioid adenocarcinoma, a mucinous adenocarcinoma of the gallbladder, and kin ovarian endometrioid carcinoma with a clear cell component. (uludag.edu.tr)
Although this most common gynecologic cancer carries the best prognosis, it is important to differentiate between the classic endometrioid tumors that tend to be estrogen dependent and well differentiated, from other less common high-risk uterine malignancies, such as uterine papillary serous carcinomas (UPSCs), clear cell carcinomas, mixed mullerian tumors (MMTs), or sarcomas, which appear to have a different biology. (medmuv.com)
Kirsten (Ki)-ras activating point mutations in codons 12 and 13 have been implicated in the development of atypical endometrial hyperplasias and endometrioid carcinomas in Japanese women, as well as in colon cancers. (medmuv.com)
Notable was the almost complete absence of Ki-ras mutations in an aggressive form of endometrial cancer, UPSC, when compared to the usual endometrioid tumors. (medmuv.com)
Histologically, most of them are serous or mucinous, but endometrioid, clear cell, Brenner (transitional cell) or mixed histotypes can be also seen. (intechopen.com)
Endometrial cancer is usually endometrioid adenocarcinoma. (msdmanuals.com)
Загальні джерела літератури Endometrial cancer is usually endometrioid adenocarcinoma. (msdmanuals.com)
Type II tumors are usually high-grade and include grade 3 endometrioid carcinomas and tumors with nonendometrioid histology (eg, serous, clear cell, mixed cell, undifferentiated, carcinosarcoma). (msdmanuals.com)
Endometrioid adenocarcinomas account for about 75 to 80% of endometrial cancers. (msdmanuals.com)
The first (Type I) pathway leads to borderline tumors, which can develop into low-grade serous, mucinous, endometrioid, and clear cell carcinomas. (hindawi.com)
At that time, the initial histopathological diagnosis was extra-uterine low grade endometrioid stromal sarcoma (EESS), and the performed endometrial biopsy showed atrophic endometrium with no evidence of tumor. (biomedcentral.com)
Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)
We examined whether tumour expression of RB1 was associated with survival across ovarian cancer histotypes (HGSC, endometrioid (ENOC), clear cell (CCOC), mucinous (MOC), low-grade serous carcinoma (LGSC)), and how co-occurrence of germline BRCA pathogenic variants and RB1 loss influences long-term survival in a large series of HGSC. (bvsalud.org)
Molecular markers in recurrent stage I, grade 1 endometrioid endometrial cancers. (ucdenver.edu)
Type I tumors include low-grade serous, low-grade endometrioid, clear cell and mucinous carcinomas and type II include high-grade serous, high-grade endometrioid and undifferentiated carcinomas. (biomedcentral.com)

and partial omentectomy for endometrial carcinoma accompanied by an adnexal mass. (uludag.edu.tr)
Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
OBJECTIVES: I. Evaluate the efficacy of paclitaxel and carboplatin with amifostine on progression free survival and overall survival in patients with metastatic or recurrent epithelial endometrial carcinoma not amenable to surgery or radiotherapy. (knowcancer.com)
Chromosome 17p is frequently involved, which contains the p53 gene known to confer a poor prognosis in endometrial cancers when mutated or deleted, and which plays an important role in the transition to carcinoma from atypical hyperplasia. (medmuv.com)
Endometrial carcinoma is commonly classified into 2 types. (msdmanuals.com)
We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma. (ijpmonline.org)
Type II tumors include high-grade serous carcinoma, malignant mixed mesodermal tumors, and undifferentiated carcinomas. (hindawi.com)
This is an open label Phase 1b/2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or in combination with ultralow dose gemcitabine in participants with platinum-resistant ovarian carcinoma , endometrial adenocarcinoma , and urothelial carcinoma based on Acrivon's OncoSignature® test status. (ucsd.edu)
Endometrial carcinoma is generally considered the most common gynecological malignancy. (radiopaedia.org)
Endometrial carcinoma is the most common gynecological malignancy, with peak incidence at around the 6th decade, though 12% of cases present in premenopausal women. (radiopaedia.org)
Endometrial carcinoma is divided into two subtypes - type I and type II. (radiopaedia.org)
Type II (20%) arises in the setting of endometrial atrophy, in females between 65 to 75 years old, and endometrial intraepithelial carcinoma. (radiopaedia.org)
See endometrial carcinoma staging for further information. (radiopaedia.org)
Staging of endometrial carcinoma is based on the FIGO staging system, which is a surgical and pathological staging following total abdominal hysterectomy , salpingo-oophorectomy, lymphadenectomy, and peritoneal washings. (radiopaedia.org)
Endometrial carcinoma usually appears as thickening of the endometrium though may appear as a polypoid mass. (radiopaedia.org)
The most frequent histologic type was represented by high-grade serous carcinoma Rare primary ovarian tumors were represented by: adult granulosa cell tumor, clear cell carcinoma, sarcoma cancer by age serous-mucinous carcinoma and undifferentiated pleomorphic sarcoma 1. (metin2kiss.ro)
The earliest age of all patients with ovarian tumors was 31 years old for the mixed serous-mucinous carcinoma. (metin2kiss.ro)

75% are benign or of borderline malignancy, and 25% are malignant The malignant form of this tumor, serous cystadenocarcinoma, accounts for approximately 40% of all carcinomas of the ovary and are the most common malignant ovarian tumors. (wikipedia.org)
Glands bearing a strong resemblance to endometrial-type glands Benign tumors have mature-appearing glands in a fibrous stroma Borderline tumors have a complex branching pattern without stromal invasion Carcinomas (malignant tumors) have invasive glands with crowded, atypical cells, frequent mitoses. (wikipedia.org)
In a series of 175 human adult tumors, gene expression was highest in ovarian serous carcinomas. (nature.com)
18 With the exception of the ovarian neoplasms, the same carcinomas analyzed for gene expression were also examined for HE4 by immunohistochemistry on tissue microarrays (see below). (nature.com)
subsequently, this group of tumors of the ovary were classified in 1973 by the World Health Organization as "low malignant potential ovarian tumor" [ 2 ] and, finally, in 2003 WHO separates them from carcinomas and call them borderline tumors. (intechopen.com)
Unlike the invasive carcinomas, borderline ovarian tumors are characterized by cytoplasmic and nuclear atypia, (element of differential diagnosis with benign tumors), absence of stromal invasion, (element of differential diagnosis with malignant tumors), unusual degree of proliferation of the epithelial cells with cellular stratification including remarkable architectural atypia and the formation of papillary protuberances. (intechopen.com)
Up to 10% of endometrial carcinomas are type II. (msdmanuals.com)
A stepwise model of progression from cystadenomas to low-grade carcinomas has been proposed for these neoplasms. (hindawi.com)
Patients and methods: RB1 protein expression patterns were classified by immunohistochemistry in epithelial ovarian carcinomas of 7436 patients from 20 studies participating in the Ovarian Tumor Tissue Analysis consortium and assessed for associations with overall survival (OS), accounting for patient age at diagnosis and FIGO stage. (bvsalud.org)
Prospective Clinical Prognostication of Endometrial Carcinomas Based on Next-Generation Sequencing and Immunohistochemistry-Real-World Implementation and Results at a Tertiary Care Center. (ucdenver.edu)
It appears that the vast majority of what seem to be primary epithelial ovarian and primary peritoneal carcinomas is, in fact, secondary from the fimbria, the most distal part of the fallopian tube. (biomedcentral.com)
Malignant mixed mesodermal tumors (carcinosarcomas) are included in the type II category because their epithelial components are identical to the pure type II carcinomas. (biomedcentral.com)
However, the vast majority of malignant ovarian tumors (80%-85%) are classified as epithelial tumors (carcinomas). (biomedcentral.com)
In contrast, 80%-90% of ovarian carcinomas are detected after the age of 40, and 40% of these tumors are detected after the age of 65. (biomedcentral.com)

Tumors of this type are also called ovarian adenocarcinoma. (wikipedia.org)
The appearance can look similar to colonic or ovarian cancer, but typically originates from the appendix (see mucinous adenocarcinoma with clinical condition Pseudomyxoma peritonei). (wikipedia.org)
Endometrial adenocarcinoma is the most common gynecologic malignancy in the United States. (medscape.com)

Borderline tumors are of uncertain malignant potential. (wikipedia.org)
Benign and borderline tumors are most common between the ages of 20 and 50 years. (wikipedia.org)
The five-year survival rate of borderline tumors and malignant tumors confined to the ovaries are 100% and 70% respectively. (wikipedia.org)
While the 5-year survival rates of borderline tumors are excellent, this should not be seen as evidence of cure, as recurrences can occur many years later. (wikipedia.org)
Clear stromal invasion is used to differentiate borderline tumors from malignant tumors. (wikipedia.org)
10-year survival rates for borderline tumors contained within the ovary, malignant tumors without invasion, and invasive malignant tumors are greater than 95%, 90%, and 66%, respectively. (wikipedia.org)
A systematic review and meta-analysis by Liu et al found that the malignancy rate, including borderline tumors, for simple ovarian cysts in postmenopausal women was approximately 1 in 10,000. (medscape.com)
Based on their tumoral behavior, we had: three cases of benign tumors, all of them associated with a different histological tumor type and grade in the contralateral ovary, 12 cases of borderline tumors and 46 cases sarcoma cancer by age sarcoma cancer follow up tumors 39 cases of primary and 7 cases of secondary tumors. (metin2kiss.ro)
Sarcoma cancer by age, Warts on hands disappear Borderline tumors occur at slightly older ages and malignant tumors are more common in women between 45 and 65 years old 2. (metin2kiss.ro)
Borderline tumors are characterized by cell proliferation and a minor degree of nuclear atypia without stromal invasion. (biomedcentral.com)

As primary ovarian mucinous tumors are usually unilateral (in one ovary), the presentation of bilateral mucinous tumors requires exclusion of a non-ovarian origin, usually the appendix. (wikipedia.org)
Tumors or cancer of the OVARY. (lookformedical.com)
Right ovary: a well circumscribed 5 × 4 cm solido-cystic tumor, the cut surface showed a vaguely lobulated whitish tumor with cystic areas filled of pasty yellowish material (Fig. 1 a). (biomedcentral.com)
Left ovary: a 6 × 4 cm whitish lobulated tumor with a cystic areas containing a chocolate-like hemorrhagic material (Fig. 1 b). (biomedcentral.com)
Our 10-year review of cellular fibromatous tumors of the ovary diagnosed at a single institution revealed four cases of cellular fibroma (CF) and three cases of MACF. (iiarjournals.org)
Cellular fibroma (CF) of the ovary is an uncommon fibromatous tumor characterized by increased cellularity compared to fibroma of the conventional type. (iiarjournals.org)
Epithelial neoplasms of the ovary are thought to arise either directly or indirectly from the ovarian surface epithelium according to incessant ovulation theory[ 4 ]. (biomedcentral.com)

Among sporadic endometrial cancers, when present, the microsatellite instability is confined to the malignant cells, and is not seen in the adjacent normal epithelium. (medmuv.com)
Although inactivation of both alleles of either hMSH2 or MLH1 (DNA mismatch repair genes) appears to underlie microsatellite instability in tumors of HNPCC kindreds, similar to the findings in sporadic colon cancers, sporadic endometrial cancers were not associated with mutations of any of the four known human mismatch repair genes. (medmuv.com)
These tumors may show microsatellite instability and have mutations in PTEN , PIK3CA , KRAS , and CTNNB 1. (msdmanuals.com)
These mutations lead to microsatellite instability in 90% of colon cancers and 75% of endometrial cancers. (medscape.com)

Studies have shown that epithelial ovarian cancer is not a single disease but is composed of a diverse group of tumors that can be classified based on distinctive morphologic and molecular genetic features [ 1 ]. (biomedcentral.com)

Endometrial cancer is usually preceded by endometrial hyperplasia. (msdmanuals.com)
They are preceded by endometrial hyperplasia. (msdmanuals.com)
Type I (80%) arises in the setting of unopposed hyperestrogenism and endometrial hyperplasia. (radiopaedia.org)
Sonographic features are non-specific and endometrial thickening can also be due to benign proliferation, endometrial hyperplasia , or polyps . (radiopaedia.org)

Malignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma. (ijpmonline.org)
Benign epithelial tumors (adenoma and cystadenoma) are characterized by the absence of cell proliferation and invasion. (biomedcentral.com)

Neoplasms in this group are thought to be derived from the ovarian surface epithelium (modified peritoneum) or from ectopic endometrial or Fallopian tube (tubal) tissue. (wikipedia.org)
Epithelial-stromal tumors are classified on the basis of the epithelial cell type, the relative amounts of epithelium and stroma, the presence of papillary processes, and the location of the epithelial elements. (wikipedia.org)
The endocervix is lined by columnar mucinous epithelium and in continuity with vaginal mucosa, the ectocervix is lined by squamous epithelium. (cytojournal.com)
By definition, serous tumors are characterized by a proliferation of epithelium resembling that lining the fallopian tubes. (medscape.com)
However, others believe it is unlikely that CICs are precursors and have instead proposed that ovarian epithelial tumors develop from müllerian-type epithelium lining paraovarian and paratubal cysts (the so-called secondary müllerian system) [ 6 ]. (hindawi.com)
In terms of origin of ovarian cancer, many of researchers and gynecologic oncologists have traditionally understood that the various different ovarian tumors are all derived from the ovarian surface epithelium (mesothelium) and that subsequent metaplastic changes lead to the development of the different cell types (Table 2 ). (biomedcentral.com)
Ovarian epithelial tumors are subclassified into several categories based on two criteria: 1) the degree of epithelial proliferation and invasion and 2) the histotype of the epithelium composing the tumor. (biomedcentral.com)

Endometrial stromal sarcoma (ESS) is a rare neoplasm accounting for only 0.2% of female genital tract tumors. (biomedcentral.com)
Endometrial stromal sarcoma (ESS) is a rare distinct pathologic entity accounting for only 0.2% of female genital tract tumors [ 1 ]. (biomedcentral.com)
We sarcoma cancer follow up 58 cases registered in the Pathology Sarcoma cancer follow up as oophorectomy or hysterectomy specimens diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological types. (metin2kiss.ro)
What to Expect When Receiving Radiation Therapy Treatment wart treatment child Mean sarcoma cancer by age distribution was 52 years old for benign tumors, 51 years old for borderline and 60 years old for malignant tumors. (metin2kiss.ro)
Two third of ovarian tumors occur in women cancer de piele obraz reproductive age sarcoma cancer by age 1. (metin2kiss.ro)

Slow growth of primary lesions. (cancer.gov)
The primary localization is the pelvis, extrapelvic lesions are extremely rare. (fortuneonline.org)
Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. (biomedcentral.com)

Another group of women at increased risk of premenopausal endometrial cancer are those with Lynch II syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC). (medscape.com)

Tumor markers are soluble glycoproteins that are found in the blood, urine, or tissues of patients with certain types of cancer. (medscape.com)
Tumor markers are not elevated in all cancer patients, particularly patients with early-stage cancer. (medscape.com)
Ovarian cancer, uterine cervical cancer, endometrial cancer, and trophoblastic neoplasms are gynecologic malignancies for which tumor markers are in clinical use. (medscape.com)
Because pathologic diagnosis of ovarian cancer is difficult without laparotomy, tumor markers such as CA-125, in addition to diagnostic imaging, are useful in preoperative evaluation for ovarian cancer. (medscape.com)
No tumor markers with high sensitivity and high specificity for endometrial cancer are known at present, although CA-125 is often used in clinical practice. (medscape.com)
The replication error (RER+) phenotype is characteristic of cancers arising in HNPCC kindreds (a familial cancer syndrome with a high incidence of colon, endometrial, gastric, and a lower incidence of ovarian and pancreatic cancers), and is also found in approximately 20% of sporadic endometrial cancers. (medmuv.com)
thus the hereditary form of endometrial cancer alone does not appear to portend a worse prognosis than the sporadic form. (medmuv.com)
Mutation of the transforming growth factor (TGF) beta receptor type II gene is common in RER+ colon and gastric cancers, but uncommon in RER+ endometrial cancers even those arising in HNPCC kindreds, suggesting that the genesis of RER+ tumors even within the same familial cancer syndrome is not the same. (medmuv.com)
Unlike most other cancers studied so far, endometrial cancer is not characterized by a small number of loci that are involved by loss of heterozygosity. (medmuv.com)
While no mutations were found in the exons of the DCC gene in endometrial cancers, chromosome 18 was found to be capable of suppressing tumorigenicity of endometrial cancer cells in nude mice by the procedure of microcell fusion, with DCC expression elevated in most of the suppressed hybrids. (medmuv.com)
Tumors or cancer of the human BREAST. (lookformedical.com)
Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance. (lookformedical.com)
Endometrial cancer is more common in high-income countries where obesity rates are high. (msdmanuals.com)
Endometrial cancer affects mainly postmenopausal women. (msdmanuals.com)
Key Statistics for Endometrial Cancer. (msdmanuals.com)
Most endometrial cancer is caused by sporadic mutations. (msdmanuals.com)
endometrial cancer due to inherited mutations tends to occur at a younger age and is often diagnosed 10 to 20 years earlier than sporadic cancer. (msdmanuals.com)
Molecular genetics and immunopathologic analysis of bladder cancer have shown some abnormalities in a number of genes and proteins that have been implicated in the development and progression of such tumors, mainly in the p53 pathway. (ijpmonline.org)
Uterine cancer is defined as any invasive neoplasm of the uterine corpus. (medscape.com)
No evidence suggests that routine endometrial sampling or transvaginal sonography to evaluate the endometrial stripe in asymptomatic women has a role in early detection of uterine cancer, even in women who take tamoxifen after breast cancer or has a cancer syndrome. (medscape.com)
This article discusses endometrial cancer and uterine sarcomas. (medscape.com)
While endometrial cancer affects reproductive age as well as postmenopausal women, 75% of endometrial cancers occur in postmenopausal women, with the mean age of diagnosis at 61 years. (medscape.com)
This is an autosomally dominant germline mutation in DNA mismatch repair (MMR) genes ( MSH1 , MSH2 , MSH6 ) and accounts for 9% of patients younger than 50 years with endometrial cancer. (medscape.com)
Besides colon cancer, women affected have a 40-60% risk of endometrial cancer by age 70 years, compared to a baseline population risk of 1.5% at the same age. (medscape.com)
Spatial Transcriptomics Depict Ligand-Receptor Cross-talk Heterogeneity at the Tumor-Stroma Interface in Long-Term Ovarian Cancer Survivors. (viictr.org)
A soft polypoid mass, which is a rare form of primary vaginal cancer. (brainscape.com)
A few notes on each cancer site and its subgroups staining techniques (e.g., glandular and diffuse neoplasms of are included in this chapter. (who.int)
Over the past three decades, surgical tumor debulking, followed by platinum-based chemotherapy is the standard treatment for advanced ovarian cancer. (biomedcentral.com)
Endometrial cancer is one of the (less common) causes of cannonball metastases to the lung. (radiopaedia.org)
Practice patterns and survival in FIGO 2009 stage 3B endometrial cancer. (ucsd.edu)
Assessment of malnutrition by unintentional weight loss and its implications on oncologic outcomes in patient with locally advanced cervical cancer receiving primary chemoradiation. (ucsd.edu)

Etiology Thecoma-fibroma tumors are a closely related group of benign tumors that arise from ovarian stroma and are often difficult for the imager and even pathologist to distinguish. (symptoma.com)

Microscopic pathological features determine whether a surface epithelial-stromal tumor is benign, a borderline tumor, or malignant (evidence of malignancy and stromal invasion). (wikipedia.org)
Components can include: cystic areas cystic and fibrous areas predominantly fibrous areas The chance of malignancy of the tumor increases with the amount of solid areas present, including both papillary structures and any necrotic tissue present. (wikipedia.org)
They are typically produced by tumor cells, but in some cases they may be produced by the body in response to malignancy or to certain benign conditions. (medscape.com)

Chromosome 18q contains the DCC gene, a putative tumor suppressor gene frequently mutated in colon cancers. (medmuv.com)
These data strongly suggest that some gene on chromosome 18, is a tumor suppressor gene in endometrial cancers. (medmuv.com)
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. (lookformedical.com)
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. (lookformedical.com)
Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm. (lookformedical.com)
They are characterized by a high frequency of mutations in TP53 , a tumor suppressor gene, and a high proliferative index. (hindawi.com)

Malignant serous tumors occur later in life on average, although somewhat earlier in familial cases. (wikipedia.org)
Most of the cervical epithelial neoplasms and their precursors occur at the squamocolumnar junction or within the transformation zone. (cytojournal.com)
In general, type I tumors are genetically more stable than type II tumors and display a distinctive pattern of mutations that occur in specific cell types. (biomedcentral.com)
Approximately two-thirds of ovarian tumors occur in women during reproductive age, whereas less than 5% occur in children. (biomedcentral.com)
60% of these tumors occur in females under the age of 40. (biomedcentral.com)

In endometrial cancers, most chromosomes contain regions of sustained allelic loss. (medmuv.com)
Other frequently involved regions include 10q, 3p, and 18q, with no significant differences found in the chromosomal regions involved in endometrial from cervical cancers. (medmuv.com)
Recent studies of endometrial cancers arising in US women, however, show the prevalence of such mutations to be significantly lower (11% versus 31%) than in Japan . (medmuv.com)
Overexpression of HER-2/neu has been associated with advanced stage, deep myometrial invasion, and poor survival in endometrial cancers in several studies. (medmuv.com)
When multivariate analysis was used to determine if HER-2/neu was an independent prognostic factor in endometrial cancers taking into account other molecular features such as DNA ploidy, epidermal growth factor receptor, or p53 status, HER-2/neu status failed to achieve significance. (medmuv.com)
Invasive neoplasms of the female pelvic organs account for almost 15% of all cancers in women. (medscape.com)
They represent 30% of all epithelial tumors and 80%-85% of all ovarian cancers. (biomedcentral.com)

At pathology, the right adnexal mass was found to be a borderline serous papillary tumor. (symptoma.com)
Type I tumors are clinically indolent and usually present at a low stage, while type II tumors exhibit papillary, grandular, and solid patterns and are highly aggressive and almost always present in advanced stage (Table 1 ). (biomedcentral.com)

Pathologists and clinicians should be aware of this rare entity to prevent misdiagnosis of MACF as fibrosarcoma or adult granulosa cell tumor and resultant overtreatment. (iiarjournals.org)

Surface epithelial-stromal tumors are a class of ovarian neoplasms that may be benign or malignant. (wikipedia.org)
They appear similar to other surface epithelial-stromal tumors, with solid and cystic areas. (wikipedia.org)

Beta-hCG and alpha-fetoprotein have proved to be useful markers for ovarian germ cell tumors. (medscape.com)
Hall KC, Post MD, Alldredge J, Aisner DL, Berning A. Molecular Evidence for Epithelial Origin of Mixed Ovarian Epithelial-Germ Cell Neoplasms: Report of 2 Cases and Review of Literature. (ucdenver.edu)
The ovaries consist of different types of tissue ( epithelial , germ cells, and sex cord tissue), which may give rise to benign or malignant tumors . (amboss.com)
These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. (biomedcentral.com)
According to the 2014 World Health Organization (WHO) classification and tumor morphology, primary ovarian tumors are subdivided into three categories: epithelial (60%), germ cell (30%), and sex-cord stromal tumors (8%)[ 1 ]. (biomedcentral.com)
Malignant germ cell and sex-cord stromal tumors comprise approximately 10% of all malignant ovarian tumors. (biomedcentral.com)

In the present study, Oct-4, CD44, and E-cadherin expressions were evaluated in eutopic and ectopic endometrial tissue samples from women with endometrioma ( n = 32) and compared with those of control endometrial tissue samples from women without endometrioma ( n = 30). (biomedcentral.com)
Immunohistochemical expression of Oct-4 was significantly higher in the ectopic endometrial tissue samples of women with endometrioma than in the control endometrial tissue samples ( p = 0.0002). (biomedcentral.com)
Conversely, CD44 and E-cadherin expressions were significantly lower in the ectopic endometrial tissue samples of women with endometrioma than in the control endometrial tissue samples ( p = 0.0137 and p = 0.0060, respectively). (biomedcentral.com)
It is caused by the growth of ectopic endometrial tissue outside the uterine cavity. (fortuneonline.org)

Mucinous tumors: Closely resemble their serous counterparts but unlikely to be bilateral Somewhat less common, accounting for about 25% of all ovarian neoplasms In some cases mucinous tumors are characterized by more cysts of variable size and a rarity of surface involvement as compared to serous tumors Also in comparison to serous tumors, mucinous tumors are less frequently bilateral, approximately 5% of primary mucinous tumors are bilateral. (wikipedia.org)
A 2-year interim analysis from the International Ovarian Tumor Analysis Phase 5 (IOTA5) study showed that 80% of ovarian cysts considered benign on ultrasonography either disappeared or required no intervention. (medscape.com)

The remaining sarcomas are made up of heterologous tumors-tumors that contain histologic components foreign to the uterus, such as rhabdomyosarcomas , osteosarcomas , and chondrosarcomas . (medscape.com)

A thickened endometrium requires endometrial sampling. (radiopaedia.org)

Gestational trophoblastic diseases (GTD) encompass a spectrum of interrelated conditions: Hydatidiform mole (HM) Invasive mole (IM) Choriocarcinoma (CC) Placental site trophoblastic tumour (PSTT) This article is available only as. (annals.edu.sg)

Characterized byvtche presence of tumor necrosis, cytologic atypia and mitotic activity. (brainscape.com)
The 2003 WHO Classification designated ovarian fibromatous tumor with markedly increased cellularity, increased mitotic activity (≥4 per 10 HPFs), and diffuse moderate-to-severe cytological atypia as fibrosarcoma ( 2 ). (iiarjournals.org)
Since tumors with increased mitotic activity but no diffuse moderate-to-severe cytological atypia have not been categorized ( 7 ), this kind of tumor has been diagnosed mostly as fibrosarcoma. (iiarjournals.org)

mucinous and Brenner malignant tumors potentially develop from the Walthard nests. (biomedcentral.com)

Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. (lookformedical.com)
It is mostly seen in obese women between 55 to 65 years old and is a well-differentiated tumor with relatively slow progression and a more favorable outcome 19 . (radiopaedia.org)

We present a case of polypoid endometriosis in a postmenopausal 58 years old patient presenting with a pelvic retroperitoneal nodule mimicking a neoplasm. (fortuneonline.org)

These are for the most part low-grade tumors that are characterized by a high frequency of mutations of KRAS , BRAF, ERBB2, CTNNB1 (the gene encoding beta catenin), and PIK3CA , low proliferation, and a 5-year survival of approximately 55% [ 2 ]. (hindawi.com)
80% of cases) and CCNE1 (encoding cyclin E1) amplification but rarely has mutations that characterize most type 1 I tumors such as KRAS, BRAF, ERBB2, PTEN, CTNNB1, and PIK3CA [ 6 ]. (biomedcentral.com)
Type II tumors which show greater morphologic and molecular homogeneity are genetically unstable and have a very high frequency of TP53 mutations. (biomedcentral.com)

The various tumor markers differ in their usefulness for screening, diagnosis, prognosis, assessing therapeutic response, and detecting recurrence. (medscape.com)
Borderline ovarian tumors represent 10-20% of epithelial ovarian neoplasm's [ 5 ] with an incidence of 1.8-4.8 out of 100.000 women per year [ 6 ] and typically have an excellent prognosis. (intechopen.com)

3 Inflammatory myofibroblastic tumour appears as a hypo or iso-attenuating mass compared with skeletal muscle depending on the amount of myxoid or collagenous stroma, respectively. (sajr.org.za)
Produces a "barrel cervix" if the tumor encircles the cervix and invades the underlying stroma. (brainscape.com)
Nests of endometrial stroma, glands or both are found in the myometrium, in between muscle bundles. (brainscape.com)
Characterized by the presence of endometrial glands and stroma in a location outside the endomyometrium. (brainscape.com)

May form very large cystic masses, with recorded weights exceeding 25 kg Mucinous tumors are characterized by a lining of tall columnar epithelial cells with apical mucin and the absence of cilia, similar in appearance with benign cervical or intestinal epithelia. (wikipedia.org)
Epithelial cystic tumors account for about 60% of all true ovarian neoplasms. (medscape.com)
Five months later (November 2017), MRI was performed and revealed 2 latero-uterine (ovarian) solido-cystic tumors measuring 60 × 53 mm (left) and 47 × 40 mm (right), along with 2 pelvic masses (located in the recto-vaginal fascia and in the vicinity of the uterine cervix). (biomedcentral.com)

Retrograde menstruation is the most widely hypothesized cause for the implantation of endometrial tissue in the peritoneal cavity and the survival of endometrial cells [ 10 ]. (biomedcentral.com)
We examined RB1 expression and germline BRCA status in a subset of 1134 HGSC, and related genotype to survival, tumour infiltrating CD8+ lymphocyte counts and transcriptomic subtypes. (bvsalud.org)

Anatomy4

Organisms7

Diseases158

Chemicals and Drugs23

Analytical, Diagnostic and Therapeutic Techniques and Equipment40

Phenomena and Processes26

Disciplines and Occupations1

Information Science4

Health Care7

Endometrioid16

Carcinoma18

Carcinomas14

Adenocarcinoma3

Borderline tumors10

Ovary7

Microsatellite instability4

Group of tumors1

Hyperplasia4

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Epithelium7

Sarcoma5

Lesions3

Hereditary Nonpolyposis1

Cancer31

Benign tumors1

Malignancy3

Suppressor6

Occur5

Cancers7

Papillary2

Adult granulosa cell1

Epithelial-stromal tumors2

Germ6

Ectopic endometrial tissue4

Cysts2

Histologic1

Endometrium1

Invasive1

Atypia3

Brenner1

Progression2

Postmenopausal1

Mutations3

Prognosis2

Stroma4

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Survival2