DermisFibroblastsSkinCells, CulturedScleroderma, SystemicMatrix Metalloproteinase 1CollagenFibroblast Growth Factor 2KeloidCollagen Type IWound HealingSkin Physiological PhenomenaKeratinocytesFibroblast Growth FactorsSkin AgingRNA, MessengerExtracellular MatrixCell LineReceptors, Fibroblast Growth FactorScleroderma, DiffuseGene Expression RegulationCicatrix, HypertrophicSignal TransductionCell DivisionUltraviolet RaysFibroblast Growth Factor 1FibrosisCollagenasesGene ExpressionTransforming Growth Factor beta1Up-RegulationTransforming Growth Factor betaCell ProliferationProcollagenCoculture TechniquesEpidermisReceptor, Fibroblast Growth Factor, Type 1Collagen Type IIIFibronectinsGelsInterleukin-1Cell DifferentiationActinsCell MovementCell Culture TechniquesCulture Media, ConditionedMatrix Metalloproteinase 3CicatrixCell TransdifferentiationTransfectionSmad3 ProteinReceptor, Fibroblast Growth Factor, Type 2Blotting, WesternMateria MedicaSkin, ArtificialCell AgingMolecular Sequence DataCell AdhesionTissue Inhibitor of Metalloproteinase-13T3 CellsBase SequenceCell CommunicationDose-Response Relationship, DrugSynovial MembraneConnective Tissue Growth FactorExtracellular Matrix ProteinsConnective TissueInduced Pluripotent Stem CellsReverse Transcriptase Polymerase Chain ReactionPhosphorylationGrowth SubstancesPlatelet-Derived Growth FactorCell SurvivalForeskinHyaluronic AcidDNAGranulation TissueIntegrin alpha2Transcription, GeneticGene Expression Regulation, EnzymologicRecombinant ProteinsDown-RegulationPseudoxanthoma ElasticumMarfan SyndromeTumor Necrosis Factor-alphaFluorescent Antibody TechniqueImmunohistochemistryTheaceaeTropoelastinReceptor, Fibroblast Growth Factor, Type 3Dermatologic AgentsProto-Oncogene Proteins c-sisMatrix Metalloproteinase 2Osteoarthropathy, Primary HypertrophicTime FactorsPhenotypePromoter Regions, GeneticMutationScleroderma, LocalizedGlycosaminoglycans