Primary cutaneous. Medical search. Frequent questions

In order of decreasing incidence, squamous cell carcinoma (SCC), basal cell carcinoma (BCC), basosquamous cell carcinoma, and melanoma account for 90% of primary malignant tumors of the hand. (medscape.com)
The Melanoma & Skin Center offers specialized treatment for patients with cutaneous T-cell lymphomas and other rare skin cancers. (mdanderson.org)
The present study investigated the BRAF V600E mutation frequency and its clinical implications in a group of 77 primary cutaneous melanoma patients treated in a cancer reference center in Brazil. (geneticsmr.org)
Regional node dissection in primary cutaneous melanoma. (blogspot.com)
BACKGROUND: The key prognostic factors for staging patients with primary cutaneous melanoma are Breslow thickness, ulceration, and sentinel lymph node (SLN) status. (lu.se)
The primary aim of this study was to establish whether SLN status is prognostic in T4 melanoma tumors. (lu.se)
METHODS: Data for all patients with a diagnosis of primary invasive cutaneous melanoma of Breslow thickness. (lu.se)
METHODS: Data for all patients with a diagnosis of primary invasive cutaneous melanoma of Breslow thickness greater than 1 mm in Sweden between 2007 and 2020 were retrieved from the Swedish Melanoma Registry, a large prospective population-based registry. (lu.se)

However, several monoclonal antibodies drug agents in patients with advanced primary cutaneous lymphomas demonstrate promising efficacy and manageable safety profiles. (uzh.ch)
Further studies to define clinical safety profile in the patient cohort with cutaneous lymphomas are needed. (uzh.ch)
Primary cutaneous CD8-positive aggressive epidermotropic T-cell lymphoma is a rare and poorly characterized variant of cutaneous lymphoma still considered a provisional entity in the latest 2016 World Health Organization Classification of Cutaneous lymphomas. (escholarship.org)
Primary Cutaneous Composite Lymphomas. (nih.gov)
Cutaneous B-cell lymphomas: 2019 update on diagnosis, risk stratification, and management. (nih.gov)
Modern radiation therapy for primary cutaneous lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group. (nih.gov)
The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. (nih.gov)
WHO-EORTC classification for cutaneous lymphomas. (nih.gov)
Every donation will go towards providing education , support , advocacy efforts, raising awareness and funding research for people affected by cutaneous lymphomas worldwide. (clfoundation.org)
CTCL is a term for a group of rare malignant lymphomas with primary manifestation in the skin. (biopharminternational.com)
Primary cutaneous B-cell lymphomas (PCBCL) are rare types of extranodal non-Hodgkin's lymphoma. (unicatt.it)
Cutaneous lymphomas represent a unique group of lymphomas and are the second most frequent extranodal lymphomas. (medscape.com)
B-cell lymphomas account for the majority of nodal lymphomas, whereas primary cutaneous B-cell lymphomas (CBCLs) represent 20-25% of all cutaneous lymphomas. (medscape.com)
Likewise, with primary cutaneous lymphomas associated with a poorer prognosis, treatment is different for isolated or grouped lesions than for multiple lesions (see Treatment and Management). (medscape.com)
The frequency of cutaneous lymphomas is 0.3 case per 100,000 population per year, with 10% (in the United States) to 20% (in Europe) being cutaneous B-cell lymphomas (CBCLs), marginal zone lymphomas, or follicle center lymphomas (FCLs). (medscape.com)
Diseases formerly designated as reticulosis or reticulosarcomatosis are currently classified according to the World Health Organization (WHO)/European Organization for Research and Treatment of Cancer (EORTC) classification (WHO-EORTC classification) for primary cutaneous lymphomas and the WHO classification. (medscape.com)
Marginal zone B-cell lymphoma (MZL) (MALT-type) is an indolent cutaneous lymphoma, accounting for approximately 10% of all cutaneous lymphomas. (medscape.com)

The patient remains well and free from any cutaneous or systemic symptoms 9 months after initial consultation. (cdlib.org)
The primary cutaneous form of ALCL (PC-ALCL), seen in the image below, is defined by skin-only involvement without systemic dissemination at presentation. (medscape.com)
The initial diagnostic evaluation of patients with any lymphoproliferative malignancy should include a careful history and physical examination, with close attention paid to the presence of systemic B symptoms, lymph node involvement, organomegaly, and evidence of cutaneous involvement. (medscape.com)
Here we identified three unrelated boys with perinatal-onset of neutrophilic cutaneous small vessel vasculitis and systemic inflammation. (nature.com)
AIDS-related NHL can be categorized into systemic NHL, primary CNS lymphoma, and primary effusion lymphoma [ 2 ]. (hindawi.com)
Primary Cutaneous Lichen Amyloidosis is a rare condition in which there is a deposition of amyloid in the dermis layer of the skin without systemic involvement. (247healthblog.com)
Cutaneous lymphosarcoma may occur as a disease in which the skin is the initial and primary site of involvement, or it may be secondary to systemic, internal disease. (merckvetmanual.com)
Cutaneous vasculitis may be limited to the skin, or may be a component of a systemic primary or secondary vasculitic disorder. (msdmanuals.com)

The malignant osseous tumors consisted of two primary lesions (an osteosarcoma and a chondrosarcoma) and two that had metastasized to the hand (one from a lung carcinoma and the other from a chondrosarcoma). (medscape.com)
Evaluating cutaneous lesions may include radiographic studies of the chest, computed tomography (CT) or magnetic resonance imaging (MRI) scans, and evaluation of other anatomic structures. (medscape.com)
During March 13-June 23, 2018, anthrax-like cutaneous lesions attributed to the Bacillus cereus group of organisms developed in 12 newborns in India. (cdc.gov)
We suggest that the synergistic interaction of nonhemolytic enterotoxin and sphingomyelinase might have a role in the development of cutaneous lesions. (cdc.gov)
A biopsy should be performed for any lesion suspected of being a cutaneous neoplasm to rule out basal cell carcinoma and other dermal lesions. (medscape.com)
Scholars@Duke publication: Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions. (duke.edu)
A rare acquired skin disease characterized by benign proliferation of mature plasma cells with a typical triad of cutaneous lesions polyclonal hypergammaglobulinemia and superficial lymphadenopathy without an apparent underlying cause. (globalgenes.org)
Primary malignant neoplasms of the sweat glands are rare, constituting less than 1% of all primary malignant skin lesions 1 . (bvsalud.org)
Two patients also had lesions clinically and histopathologically compatible with primary anetoderma. (tau.ac.il)
Lymphocutaneous nocardiosis is rare and often misdiagnosed as sporotrichosis (more common) because it also manifests as a primary lesion at the site of injury, followed by a proximal spread of lymphangitis and nodular lesions along the lymphatics. (medscape.com)

Representative examples include cutaneous marginal zone B-cell lymphoma and cutaneous follicle center lymphoma. (nih.gov)
Cutaneous B-cell lymphoma includes follicle centre, marginal zone, and diffuse large B-cell lymphoma, which have all been reported to respond to intravenous rituximab. (dermnetnz.org)
Conclusions: Anetodermic primary cutaneous B-cell lymphoma is a rare and unique clinicopathological manifestation not only of marginal-zone lymphoma, as previously described, but also of follicle-center cell lymphoma. (tau.ac.il)

This 2-part continuing medical education article will review primary cicatricial alopecias according to the working classification suggested by the North American Hair Research Society. (unboundmedicine.com)
The American Joint Committee on Cancer (AJCC) tumor/node/metastasis (TNM) classification, prognostic staging groups, and histologic grades for cutaneous carcinoma of the head and neck are provided below. (medscape.com)

Primary localized cutaneous amyloidosis (PLCA) is a condition in which clumps of abnormal proteins called amyloids build up in the skin, specifically in the wave-like projections (dermal papillae) between the top two layers of skin (the dermis and the epidermis). (medlineplus.gov)
In primary localized cutaneous amyloidosis, the deposition of amyloid occurs in previously apparent normal skin with no evidence of deposits occurring in the internal organs. (247healthblog.com)

Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) are the first and second most common types of skin cancer, respectively. (medscape.com)
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer and one of the most common cancers overall in the United States. (medscape.com)
Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human skin cancer with at least 200,000 to 400,000 new cases of cSCC expected each year in the US. (aad.org)

A diagnosis of cutaneous mucinous carcinoma was made. (cdlib.org)
Polymerase chain reaction testing using Mycobacterium genus- and Mycobacterium tuberculosis species-specific primers confirmed the clinical diagnosis of cutaneous tuberculosis. (qxmd.com)

The lack of an integrated national system prevents the Islamic Republic of Iran from registering and reporting all cases of cutaneous leishmaniasis. (who.int)
To establish a laboratory network for the improvement of diagnosis and surveillance of cutaneous leishmaniasis in endemic areas of the Islamic Republic of Iran using parasitological and molecular methods. (who.int)
This descriptive, cross-sectional, pilot study examined 49 laboratories in the 2 endemic areas for cutaneous leishmaniasis in the Islamic Republic of Iran. (who.int)
Samples were taken for identification of the dominant Leishmania species from individuals with cutaneous leishmaniasis referred to the laboratories and had not travelled to other endemic regions. (who.int)
Network implementation reduced relapse of cutaneous leishmaniasis. (who.int)
Implementation of a cutaneous leishmaniasis laboratory network can enhance diagnosis, unify diagnostic methods and improve patient care. (who.int)
There are 3 types of leishmaniasis: visceral, cutaneous, and mucocutaneous, and cutaneous leishmaniasis (CL) is the most prevalent. (who.int)
The characteristic residual scarring (inactive CL) following almost all cases of active cutaneous leishmaniasis (CL) has recently been recognised as part of the CL disease spectrum due to its lasting psychosocial impact. (dndi.org)

Clarification for the origin (either primary or secondary to skin) of the tumor via immunostaining to assess for a myoepithelial in situ component was performed, yielding a negative result. (cdlib.org)
Cutaneous angiosarcoma is an uncommon, potentially metastatic and highly aggressive vascular tumor that may arise as de novo or be associated with previous radiotherapy. (sdu.edu.tr)
This study aimed to report and discuss the challenging differential diagnosis between a primary tumor of sweat glands and cutaneous metastasis of mammary carcinoma using anatomopathological and imaging diagnostic resources available today. (bvsalud.org)
The findings show the challenge in differentiating a primary tumor of the sweat gland from a metastatic cutaneous tumor of mammary carcinoma, even with the immunohistochemical resources currently available. (bvsalud.org)
Neoadjuvant chemotherapy for primary cutaneous/soft tissue angiosarcoma: Determining tumor behavior prior to surgical resection. (lvhn.org)
The tumor type and the extent of cutaneous involvement are the 2 most relevant prognostic factors in primary CBCL. (medscape.com)

We recommend the term primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphoma as this more broad designation better describes this clinical-pathologic presentation, which allows the inclusion of cases with CD8 negative and/or αβ/γδ T-cell receptor chain double-positive or double-negative expression. (escholarship.org)
Striking clinical features include frequent cutaneous and extranodal involvement, young age at presentation, and male predominance. (medscape.com)
The FDA's action marks the conversion of an accelerated approval indication to full approval and is based on data from a Phase 3 clinical trial that evaluated the overall efficacy and safety of ONTAK in certain patients with recurrent cutaneous T-cell lymphoma (CTCL). (biopharminternational.com)
Observations: We analyzed data from 5 patients (3 male, 2 female) with clinical and histopathological features of anetodermic primary cutaneous B-cell lymphoma. (tau.ac.il)
Primary cutaneous nocardiosis, most commonly caused by Nocardia brasiliensis , typically affects immunocompetent individuals with a history of trauma and can be subdivided into 3 clinical entities that include (1) lymphocutaneous infection, (2) mycetoma, and (3) superficial skin infection, including ulceration, abscess, and cellulitis. (medscape.com)

What are the Symptoms of Primary Cutaneous Lichen Amyloidosis? (247healthblog.com)
What is the Cause of Primary Cutaneous Lichen Amyloidosis According to Ayurveda? (247healthblog.com)
According to Ayurveda, the cause of primary cutaneous lichen amyloidosis is the accumulation of endotoxins or Ama in the body. (247healthblog.com)
This churna also removes Ama formation or endotoxins within the system therefore quite effective for the treatment of primary cutaneous lichen amyloidosis. (247healthblog.com)
reticulum cell sarcomas, cutaneous nodular amyloidosis) are relatively common cutaneous tumors. (merckvetmanual.com)

The Cutaneous Lymphoma Foundation is here to empower, champion for, and unite the cutaneous lymphoma community. (clfoundation.org)

These can be divided into primary and metastatic tumors. (medscape.com)
Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
BACKGROUND: Given the propensity for hematogenous metastases, neoadjuvant chemotherapy (NAC) could treat occult metastatic disease early, potentially improving survival and better defining which primary angiosarcomas (AS) benefit from surgical resection. (lvhn.org)

Results: The interviewed physicians reported that late presentation with dcSSc was common, with some patients presenting to primary care physicians after symptoms had persisted for up to 1 year. (uzh.ch)
Conclusion: Patients and primary healthcare providers can be unaware of the symptoms of dcSSc, therefore presentation and referral to specialist care are often late. (uzh.ch)

Primary mucinous carcinoma (PMC) of the skin is a rare malignant neoplasm deriving from sweat glands [ 1 ]. (cdlib.org)
[ 3 ] A biopsy should be performed for any lesion suspected of being a cutaneous neoplasm. (medscape.com)

PC-ALCL is one of the primary cutaneous CD30 + T-cell lymphoproliferative disorders, a wide spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end of the spectrum and PC-ALCL at the malignant end. (medscape.com)

CSVV sometimes refers to small-vessel vasculitis of unknown cause (also called idiopathic cutaneous small-vessel vasculitis). (msdmanuals.com)

We present a case of a patient with HIV/AIDS who presented with a tender left lower extremity cutaneous mass over a site of previous cryptococcal infection and was found to have plasmablastic lymphoma (PBL). (hindawi.com)
We present a rare case of a 63-year-old HIV-positive male who was found to have plasmablastic lymphoma on biopsy of a tender left lower extremity cutaneous mass occurring over a previous site of cryptococcal infection. (hindawi.com)
Cutaneous candidiasis is infection of the skin with candida fungus. (health32.com)

The diagnosis of CBCL is established by analysis of skin biopsy specimen, using histomorphology and cytomorphology, immunohistochemistry and phenotypic features, and genotyping and cytogenetic studies (see Workup of Cutaneous B-Cell Lymphoma). (medscape.com)

About 20% of all patients in the Care Center have cutaneous T-cell lymphoma, or CTCL, which is a type of Non-Hodgkin lymphoma . (mdanderson.org)
1 - 3 Primary pulmonary disease is often self-limiting, but some patients fail to recover and develop complications or chronic pulmonary disease (approximately 5 to 10% of cases). (cdc.gov)
Patients diagnosed with cSCC should have annual checks for recurrence or other new primary skin cancer(s). (aad.org)
A systematic search using PubMed, Scopus, and Cochrane library was performed to identify full original articles analyzing the safety of RT in patients with PCBCL with the primary outcome to assess the acute and late skin toxicity. (unicatt.it)
METHODS: A retrospective comparison was performed of 23 patients with resectable, localized cutaneous/soft tissue primary AS treated with surgery alone (S, n = 13) or NAC followed by surgery (NAC-S, n = 12). (lvhn.org)
Thus, improved awareness among patients and primary care physicians is necessary to facilitate earlier referral and diagnosis. (uzh.ch)
not in patients with primary anetoderma). (tau.ac.il)
CDC, our planners and presenters wish to disclose they have no financial relationships with ineligible companies whose primary business is producing, marketing, selling, reselling, or distributing healthcare products used by or on patients. (cdc.gov)

This ulcerated nodule of localized primary cutaneous CD30+ anaplastic large cell lymphoma is relatively nonspecific in appearance. (medscape.com)

Cutaneous T - cell lymphoma is a rare type of extranodal non-Hodgkin's lymphoma that primarily affects the skin. (nih.gov)

Primary malignant tumors are subdivided further into skin tumors, musculoskeletal tumors, and soft tissue tumors. (medscape.com)
Bone and soft tissue malignancies of the hand are much less common than cutaneous malignant tumors. (medscape.com)
Primary Cutaneous Neuroendocrine Tumors Ceruminous gland tumors are discussed in Tumors of the Ear Canal. (merckvetmanual.com)

A less common presentation of cSCC includes a pink cutaneous nodule without overlying surface changes. (medscape.com)
In cutaneous ectopic brain (CEB), evaluate any bald scalp plaque or nodule with suitable noninvasive diagnostic techniques (eg, ultrasound, cranial tomograms), with input from a neurosurgeon. (medscape.com)

Cutaneous vasculitis refers to vasculitis affecting small- or medium-sized vessels in the skin and subcutaneous tissue but not the internal organs. (msdmanuals.com)

Primary cutaneous histoplasmosis is a rare skin condition, reported on the penis, characterized by a chancre-type lesion with regional adenopathy. (wikipedia.org)
The primary feature of PLCA is patches of skin with abnormal texture or color. (medlineplus.gov)
This study establishes the primary structure of human skin chymase and provides further evidence for the presence of a cathepsin G-like proteinase within human mast cells. (duke.edu)
This sequence, along with that established for the purified protein, constituted 99% of the heart chymase primary structure, strongly indicating that human skin and heart chymases have identical primary structures. (duke.edu)
In cutaneous candidiasis, the skin is infected with candida fungi. (health32.com)
Moreover, occurrence of cutaneous angiosarcoma within a short period following a previous excision in a patient with a history of multiple nonmelanoma skin cancers was interestingly pointed out. (sdu.edu.tr)
This is a retrospective case series of cutaneous squamous cell carcinomas (SCCs) which were incompletely excised in National Skin Centre, Singapore from 1991 to 1995. (annals.edu.sg)
Apocrine skin carcinoma has characteristics similar to those of cutaneous breast carcinoma metastases when it presents a tubule-lobular, or cordonal differentiation. (bvsalud.org)
Any primary or secondary vasculitis can affect the skin, including that due to serum sickness, infections (eg, hepatitis C), cancers, rheumatologic or other autoimmune disorders, and hypersensitivity to drugs. (msdmanuals.com)
The remaining primary skin infections of nocardiosis manifest as pustules, abscesses, or cellulitis and often mimic disease caused by more common organisms, such as Staphylococcus species. (medscape.com)

They performed comparative studies of the cutaneous malignancy and breast nodules, especially with immunohistochemical examinations. (bvsalud.org)

Nijmegen breakage syndrome complicated with primary cutaneous tuberculosis. (qxmd.com)
We report a 7-year-old white girl with NBS associated with cutaneous tuberculosis. (qxmd.com)
This is the first report describing the simultaneous presentation of NBS and cutaneous tuberculosis. (qxmd.com)

We report an early case of primary cutaneous mucinous carcinoma in a male patient with chronic actinic damage. (cdlib.org)

Both primary and secondary forms of cicatricial alopecia have been described. (unboundmedicine.com)
This type of secondary anetoderma, like primary anetoderma, might be associated with immunologic disorders, particularly antiphospholipid antibodies. (tau.ac.il)
Cutaneous involvement with N asteroides is usually secondary to hematogenous dissemination from a pulmonary focus. (medscape.com)

For invasive cSCC, surgical excision and Mohs micrographic surgery are the primary treatment options. (medscape.com)

The final diagnosis was primary cutaneous mucinous carcinoma and definitive treatment was carried out via wide local excision. (cdlib.org)

Primary blistering diseases (also called autoimmune bullous disorders) are associated with autoantibodies directed against various structural support proteins in the epidermis and dermoepidermal junction. (dermnetnz.org)

We sought to better characterize and provide diagnostic and therapeutic guidance of this rare cutaneous lymphoma. (escholarship.org)

Primary cutaneous coccidioidomycosis, 5 solid organ donor-derived coccidioidomycosis, 6 and fomite-transmitted coccidioidomycosis 7 - 8 can also occur but are very uncommon. (cdc.gov)
Cutaneous lymphosarcoma is uncommon but has been identified in all domestic species. (merckvetmanual.com)

Cutaneous epitheliotropic T - cell lymphoma in the dog is a rare neoplastic condition with unknown aetiology. (nih.gov)

Although the patient had no medical history of breast cancer, due to this result, she was referred to a mastologist, who investigated her breast nodules for the possible primary focus of the carcinoma. (bvsalud.org)

Ulcer on the arm of a patient with primary cutaneous nocardiosis. (medscape.com)

Advanced stage cutaneous T - cell lymphoma has a poor prognosis with significant morbidity. (nih.gov)
The Cutaneous T-Cell Lymphoma Clinic business hours are 8 a.m. to 5 p.m., Monday through Wednesday. (mdanderson.org)
Background: Primary cutaneous B-cell lymphoma manifested by anetoderma has been reported in 7 cases. (tau.ac.il)

We describe a cluster of 12 cases of severe anthrax-like cutaneous infections in otherwise healthy newborns attributed to the B. cereus group. (cdc.gov)

CONCLUSIONS: NAC for primary AS was well tolerated. (lvhn.org)

Melanoma8

Lymphomas17

Systemic8

Lesions10

Follicle3

Classification2

Localized cutaneous amyloidosis2

Squamous cell carc3

Diagnosis of cutaneous2

Leishmaniasis8

Tumor6

Clinical5

Amyloidosis5

Lymphoma Foundation1

Metastatic3

Symptoms2

Neoplasm2

Lymphoproliferative disorders1

Small vessel vasculitis1

Infection3

Workup1

Patients8

Anaplastic1

Extranodal1

Tumors3

Nodule2

Internal organs1

Skin10

Malignancy1

Tuberculosis3

Chronic1

Secondary3

Invasive1

Excision1

Bullous1

Diagnostic1

Uncommon2

Rare1

Carcinoma1

Patient1

Cell3

Infections1

CONCLUSIONS1