Squamous cell carcinomasTumorCystic CarcinomasAdenoid cysticNeuroendocrine carcinomaAdenosquamous CarcinomaNeoplasmsPleomorphic adenomaPolymorphous low-grade adenNeoplasmSituHead and neckTypes of salivaryMajor salivary glandSmall-cell lungMalignancyPulmonaryParotidAdenocarcinomaMetastaticEsophagealCarcinoid2000MetastasisOral squamousMalignant tumorsHistologicalLung carcinomaNeckBronchialBenignTumourOropharyngealThyroidIncidenceEpithelialCharacteristicsMetastasizeOvarianHigh gradeGlandularTonguePrognosis
Squamous cell carcinomas6
- Squamous cell carcinomas arise from excretory duct cells, pleomorphic adenomas arise from the intercalated duct cells, oncocytomas arise from the striated duct cells, and acinic cell carcinomas arise from acinar cells. (medscape.com)
- After therapy, the incidence of pleomorphic adenomas, mucoepidermoid carcinomas, and squamous cell carcinomas is increased. (medscape.com)
- Dr.Hyunseok "Hyu" Kang is a medical oncologist and a clinician scientist focusing on head and neck cancers including squamous cell carcinomas of head and neck (SCCHN), salivary gland cancers, thyroid cancers and other rare cancers of head and neck. (ucsf.edu)
- Squamous cell carcinomas tend to metastasize to regional lymph nodes and directly invade mediastinal structures, leading to high local and regional recurrence rates. (msdmanuals.com)
- High cytoplasmic OPN staining was observed in 100% of gastric carcinomas, 85% of colorectal carcinomas, 82% of transitional cell carcinomas of the renal pelvis, 81% of pancreatic carcinomas, 72% of renal cell carcinomas, 71% of lung and endometrial carcinomas, 70% of esophageal carcinomas, 58% of squamous cell carcinomas of the head and neck, and 59% of ovarian carcinomas. (aacrjournals.org)
- Half of all hard palate cancers are squamous cell carcinomas (SCCs) as seen in the image below. (medscape.com)
Tumor9
- Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
- The primary tumor was resected with negative margins. (scirp.org)
- There was no significant correlation of ploidy status or SPF with the tumor grades of mucoepidermoid carcinomas. (researchgate.net)
- Primary intraosseous mucoepidermoid carcinoma (PIOC) of the jaw bones is an extremely rare malignant salivary gland tumor. (bvsalud.org)
- Although squamous cell carcinoma is the most common primary malignant tumor of the oral cavity, the most common tumors of the hard palate are of minor salivary gland origin. (medscape.com)
- Carcinomatous elements in the tumor metastasize, making carcinoma ex pleomorphic adenoma a highly aggressive tumor with very low cure rates regardless of treatment. (merckmanuals.com)
- Benign cylindromas can slowly undergo malignant transformation into adenoid cystic carcinomas, the most common malignant tumor of minor salivary glands (and of the trachea). (merckmanuals.com)
- Acinic cell carcinoma, a common parotid tumor, occurs in people in their 40s and 50s. (merckmanuals.com)
- A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
Cystic Carcinomas3
- Abnormal DNA content has been related to aggressive behavior in Mucoepidermoid Carcinomas (MEC), Adenoid Cystic Carcinomas (AdCC), Acinic Cell Carcinomas (ACC) and oncocytomas (Onc) [8]. (researchgate.net)
- Adenoid cystic carcinomas are a high-grade neoplasm that has a propensity to invade and spread along nerves and therefore has a higher rate of local recurrence and/or distant metastasis, particularly to the lungs. (oncologybuddies.com)
- Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
Adenoid cystic14
- Adenoid cystic carcinoma (ACC), which commonly arises in a salivary gland, accounts for 10% of bronchial adenomas (0.04-0.2% of all lung cancers). (medscape.com)
- Adenoid cystic carcinoma behaves very similarly to major and minor salivary gland tumors. (medscape.com)
- The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities. (researchgate.net)
- These include benign tumors such as pleomorphic adenomas, as shown below, and malignant tumors such as mucoepidermoid carcinoma, adenoid cystic carcinoma, and polymorphous low-grade adenocarcinoma. (medscape.com)
- Accordingly, mucoepidermoid carcinoma (MEC) is the most frequent subtype, with more than 30% of the SGC cases, followed by the adenoid cystic carcinoma (ACC) with the pathology in 23.8% of all SGC cases, and the adenocarcinoma not otherwise specified [ 4 ]. (genominfo.org)
- Pulmonary adenoid cystic carcinoma (PACC) is an uncommon neoplasm of the lung but represents the predominant type of salivary gland-type lung carcinoma. (biomedcentral.com)
- The data presented in this work suggest that EGFR, KRAS, BRAF, ALK, PIK3CA, PDGFRA, and DDR2 may not be driver genes in primary pulmonary adenoid cystic carcinoma. (biomedcentral.com)
- Primary pulmonary adenoid cystic carcinoma (PACC) is a rare neoplasm. (biomedcentral.com)
- The most common malignant primary neoplasms are adenoid cystic and mucoepidermoid carcinomas. (oncologybuddies.com)
- A Phase 2 Trial of Rivoceranib, an Oral Vascular Endothelial Growth Factor Receptor 2 Inhibitor, for Recurrent or Metastatic Adenoid Cystic Carcinoma. (ucsf.edu)
- Approaches to the Management of Metastatic Adenoid Cystic Carcinoma. (ucsf.edu)
- Hemoptysis, while uncommon, more often occurs with a squamous cell carcinoma and can potentially lead to earlier diagnosis, whereas wheezing or stridor occurs more often with the adenoid cystic variant. (msdmanuals.com)
- Adenoid Cystic Carcinoma was the most common histological type (30.57%) and Adenocarcinoma with a prevalence of 1.91% had the lowest prevalence rate in this study. (waocp.com)
- The most widespread types of salivary gland cancer are mucoepidermoid carcinoma and adenoid cystic carcinoma. (netmeds.com)
Neuroendocrine carcinoma4
- Immunohistochemical analysis of paraffin-embedded human neuroendocrine carcinoma of the lung using Iba1/AIF-1 (E5N4J) Mouse mAb (IHC Formulated) performed on the Leica ® BOND ™ Rx. (cellsignal.com)
- Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
- As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
- RESULTS: Of the 32 cases, pathologic findings revealed squamous cell carcinoma (n = 27), mucoepidermoid carcinoma (n = 2), neuroendocrine carcinoma (n = 1), papillary thyroid carcinoma (n = 1), and adenocarcinoma (n = 1). (nyu.edu)
Adenosquamous Carcinoma2
- Primary Intrahepatic Adenosquamous Carcinoma (iASC) is a very rare subtype of Cholangiocarcinoma (CCA), with a worse prognosis than adenocarcinoma. (oncologyradiotherapy.com)
- Esophageal Primary Intrahepatic Adenosquamous Carcinoma (IASC) is defined by the coexistence of both squamous and glandular elements in the same lesion histologically. (oncologyradiotherapy.com)
Neoplasms1
- Salivary gland carcinoma (SGC) is rare cancer, constituting 6% of neoplasms in the head and neck area. (genominfo.org)
Pleomorphic adenoma9
- Background: Mucoepidermoid carcinoma ex-pleomorphic adenoma (MECxPA) is an extremely rare salivary gland malignancy. (scirp.org)
- The final pathologic diagnosis was metastatic high-grade mucoepidermoid carcinoma ex-pleomorphic adenoma. (scirp.org)
- Conclusions: We describe a novel presentation of high-grade mucoepidermoid carcinoma ex-pleomorphic adenoma as a metastatic parapharyngeal mass. (scirp.org)
- Carcinoma ex-pleomorphic adenoma (CxPA) is an uncommon malignancy, accounting for roughly 11% of primary tumors of the salivary gland. (scirp.org)
- however, the presence of mucoepidermoid carcinoma (MEC) arising from pleomorphic adenoma (PA) has been rarely reported, with a total of nine cases in the literature. (scirp.org)
- Herein, we report a case of a high-grade mucoepidermoid carcinoma ex-pleomorphic adenoma within the deep lobe of the parotid gland. (scirp.org)
- Final pathology revealed high grade mucoepidermoid carcinoma arising from a pleomorphic adenoma. (scirp.org)
- Examination of consecutive slides actually revealed small assemblies of carcinoma cells that required a final diagnosis as non-invasive carcinoma in pleomorphic adenoma. (researchgate.net)
- Once malignant degeneration of a pleomorphic adenoma occurs, it is known as carcinoma ex pleomorphic adenoma. (merckmanuals.com)
Polymorphous low-grade aden1
- Other types in order of prevalence were MUC, SCC, carcinoma ex-pleomorphic, acinic cell carcinoma, salivary duct carcinoma, polymorphous low grade adenocarcinoma and adenocarcinoma (Table1). (waocp.com)
Neoplasm5
- Salivary gland carcinoma (SGC) is an uncommon neoplasm, which constitutes approximately 6 percent of cancers in the head and neck region [ 1 , 2 ]. (genominfo.org)
- Mucoepidermoid carcinoma is a malignant neoplasm of exocrine glands that arises predominantly in salivary glands. (bvsalud.org)
- A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
- Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
- An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)
Situ1
- In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
Head and neck3
- Tobacco and alcohol, which are highly associated with head and neck squamous cell carcinoma, have not been shown to play a role in the development of malignancies of the salivary glands. (medscape.com)
- 90% of head and neck cancers are squamous cell (epidermoid) carcinomas. (merckmanuals.com)
- Clinical Trial Development in TP53-Mutated Locally Advanced and Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma. (ucsf.edu)
Types of salivary1
- It is presumed to originate from the minor salivary glands lining the tracheobronchial tree and is one of the main types of salivary gland-type carcinoma of the lung [ 1 ]. (biomedcentral.com)
Major salivary gland2
- Histopathologic image of mucoepidermoid carcinoma of the major salivary gland. (wikipedia.org)
- H & E stain Histopathologic image of mucoepidermoid carcinoma of the major salivary gland. (wikipedia.org)
Small-cell lung1
- It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA . (lookformedical.com)
Malignancy2
- Mucoepidermoid carcinoma (MEC) is the most common type of minor salivary gland malignancy in adults. (wikipedia.org)
- Introduction: Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. (bvsalud.org)
Pulmonary1
- Vascular disorders of the lung: thromboembolism, pulmonary infarction and hemorrhage, pulmonary hypertension (primary and secondary). (unibo.it)
Parotid1
- Relative incidence of parotid tumors, showing mucoepidermoid carcinoma at top right. (wikipedia.org)
Adenocarcinoma1
- Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
Metastatic4
- Fine needle aspiration (FNA) of the neck mass was consistent with poorly differentiated metastatic carcinoma, likely of squamous origin. (scirp.org)
- Positron Emission Tomography/Computed Tomography (PET/CT) clearly demonstrated hotspots (SUV max: 7.7 for the primary mass and 4.2 for the metastatic lesion) at the same locations as the tumors detected by MRI, but no hot spots for lymph nodes and distant metastases were observed ( Figure 1D ). (oncologyradiotherapy.com)
- Pantomics Array Description: Stomach cancer tissue array containing 48 cases of paired primary and metastatic tumors (in. (delos.info)
- Pantomics Array Description: Rectum cancer tissue array containing paired primary and metastatic tumors (in lymph nodes. (delos.info)
Esophageal2
- Uncommon malignant tumors of the esophagus are defined as any histological type of malignant esophageal tumors other than the typical squamous cell carcinoma. (tmu.edu.tw)
- of esophageal squamous cell carcinoma [10]. (cyberleninka.org)
Carcinoid1
- In the absence of distant metastases, the treatment of choice is complete removal of the primary carcinoid with maximal parenchymal preservation. (medscape.com)
20001
- We reviewed 24 cases of primary PACC between 2000 and 2014, including 21 cases reported in our previous study and three new cases added in 2014. (biomedcentral.com)
Metastasis3
- Most primary airway tumors are not resectable because of metastasis, locally advanced stage, or patient comorbidities. (msdmanuals.com)
- In addition, p63 and Ki-67 expression levels were associated with myoepithelial carcinoma recurrence and metastasis. (cyberleninka.org)
- Conclusions: Recurrence and metastasis in myoepithelial carcinomas are more frequent in p63-positive and Ki-67-positive EMCs, and poor prognosis is associated with overexpression of p63. (cyberleninka.org)
Oral squamous1
- Other studies in oral cancer [23,24] reported that there is no relationship between the histopathological grade of oral epithelial dysplasia or oral squamous cell carcinoma and the ploidy status. (researchgate.net)
Malignant tumors2
- Primary uncommon malignant tumors of the esophagus: an analysis of 30 cases. (tmu.edu.tw)
- 深入研究「Primary uncommon malignant tumors of the esophagus: an analysis of 30 cases. (tmu.edu.tw)
Histological1
- In addition, patients with small cell carcinoma seemed to have worse treatment outcome than those with other histological types of tumors. (tmu.edu.tw)
Lung carcinoma1
- Staging Lung carcinoma is the leading cause of cancer-related death in men and women worldwide. (msdmanuals.com)
Neck1
- Eckel HE, Volling P, Pototschnig C, Zorowka P, Thumfart W. Transoral laser resection with staged discontinuous neck dissection for oral cavity and oropharynx squamous cell carcinoma. (jamanetwork.com)
Bronchial1
- Alcian blue-PAS stain Mucoepidermoid carcinomas of the salivary and bronchial glands are characterized by a recurrent t(11;19)(q21;p13) chromosomal translocation resulting in a MECT1-MAML2 fusion gene. (wikipedia.org)
Benign1
- They are characterized by a clinical course that is usually more benign than that of bronchogenic carcinoma. (medscape.com)
Tumour3
- Background: Myoepithelial carcinoma is a rare tumour. (cyberleninka.org)
- Myoepithelial carcinoma (MEC) is a rare tumour that was first described by Stromayer et al. (cyberleninka.org)
- Similarly, under Carcinoma, specific renamed or deleted in later revisions of tumour classifications. (who.int)
Oropharyngeal2
- Transoral robotic surgery for oropharyngeal squamous cell carcinoma: a prospective study of feasibility and functional outcomes. (jamanetwork.com)
- Soft palate carcinomas are staged as oropharyngeal cancers according to the American Joint Committee on Cancer (see Staging). (medscape.com)
Thyroid2
- Mucoepidermoid carcinoma can also be found in other organs, such as bronchi, lacrimal sac, and thyroid gland. (wikipedia.org)
- Although OPN expression was identified in a good number of bladder, prostate, and brain tumors, the majority of 6 skin cancers, 11 of 14 salivary gland cancers, 2 thyroid carcinomas, and 23 of 26 breast cancers revealed low OPN positivity or were negative. (aacrjournals.org)
Incidence2
- The incidence of sebaceous carcinoma (SC) in the outer one-third of the external auditory canal is considered extremely rare, and only eight case reports have been published. (bvsalud.org)
- This carcinoma has a more indolent course, as well as an incidence of multifocality. (merckmanuals.com)
Epithelial3
- Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
- Finally, a new class was defined called carcinoma with pleomorphic, sarcomatoid, or sarcomatous elements, which brings together a number of proliferations characterized by a spectrum of epithelial to mesenchymal differentiation. (ersjournals.com)
- A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. (lookformedical.com)
Characteristics1
- Methods: Using immunohistochemistry, expression levels of p63 and Ki-67 were determined in 16 myoepithelial carcinoma samples and correlated with clinicopathological characteristics and patient prognosis. (cyberleninka.org)
Metastasize3
- The lung, kidney, breast, and skin are the most common sites of primary carcinoma that metastasize to the oral cavity. (medscape.com)
- Intermediate and high-grade mucoepidermoid carcinomas may metastasize to the regional lymphatics. (merckmanuals.com)
- The airway can be affected by primary tracheobronchial tumors, primary tumors that are adjacent to and invade or compress the airway, or cancers that metastasize to the airway. (msdmanuals.com)
Ovarian1
- Immunohistochemical analysis of paraffin-embedded human ovarian clear cell carcinoma using Iba1/AIF-1 (E5N4J) Mouse mAb (IHC Formulated) (left) or Iba1/AIF-1 (E4O4W) XP ® Rabbit mAb #17198 (right) performed on the Leica ® BOND ™ Rx. (cellsignal.com)
High grade1
- Lymph node involvement is of special concern in SCC and high-grade mucoepidermoid cancer. (medscape.com)
Glandular1
- Mucoepidermoid carcinoma (MEC) originates from glandular tissue located in the submucosa of the trachea and bronchus. (medscape.com)
Tongue3
- Tongue and tonsil carcinoma: increasing trends in the US population ages 20-44 years. (jamanetwork.com)
- Carcinoma of the tongue base treated by transoral laser microsurgery, part one: untreated tumors, a prospective analysis of oncologic and functional outcomes. (jamanetwork.com)
- Canis M, Ihler F, Wolff HA, Christiansen H, Matthias C, Steiner W. Oncologic and functional results after transoral laser microsurgery of tongue base carcinoma. (jamanetwork.com)
Prognosis1
- The large cell carcinoma class has been enriched with several variants, including the LCNEC and the basaloid carcinoma, both with a dismal prognosis. (ersjournals.com)