AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaHumanitiesInformation ScienceNamed GroupsHealth CareGeographicals
Diabetic AngiopathiesPrevalenceDiabetes Mellitus, Type 1Diabetes MellitusDiabetes Mellitus, Type 2Diabetes Mellitus, ExperimentalDiabetes ComplicationsDiabetic RetinopathyDiabetic NephropathiesPostoperative ComplicationsBlood GlucoseRisk FactorsDiabetic FootPregnancy in DiabeticsHemoglobin A, GlycosylatedHypoglycemic AgentsInsulinRetrospective StudiesStreptozocinDiabetes, GestationalCross-Sectional StudiesTreatment OutcomeHyperglycemiaTime FactorsProspective StudiesFollow-Up StudiesIncidenceObesityAge FactorsCohort StudiesAlbuminuriaIntraoperative ComplicationsDiabetic CardiomyopathiesDiabetic DietUnited StatesMice, Inbred NODGlucose Tolerance TestIslets of LangerhansBody Mass IndexSex FactorsRisk AssessmentDiabetes InsipidusCase-Control StudiesLogistic ModelsPregnancyQuestionnairesAge DistributionPrediabetic StateHypertensionInsulin ResistanceComorbidityGlucoseCardiovascular DiseasesSex DistributionPregnancy ComplicationsInfant, NewbornDiabetic NeuropathiesOdds RatioBiological MarkersSeverity of Illness IndexChi-Square DistributionReference ValuesGlycosylation End Products, AdvancedMultivariate AnalysisInsulin-Secreting CellsBody WeightHealth SurveysBrazilHypoglycemiaBlood PressureIndiaGenotypeMetforminC-PeptideGlucose IntoleranceKidney Failure, ChronicChinaBlood Glucose Self-MonitoringJapanRegression AnalysisFastingChronic DiseaseSocioeconomic FactorsDisease Models, AnimalKidneyAlloxanPredictive Value of TestsSmokingDisease ProgressionRats, WistarMetabolic Syndrome XGenetic Predisposition to DiseaseRetinal VesselsRural PopulationMass ScreeningUrban PopulationAge of OnsetReoperationAldehyde ReductaseRats, Sprague-Dawley
RetinopathyNephropathyPathogenesisKetoacidosisHypertensionGlycemic controlMicro-angiopathyIncidenceHyperglycemiaClinicalMicrovascular diseaseMellitus TypeAbstractT2DMEtiologyNeuropathyComorbidityAlbumin excretionCerebralProgressionObesityAmputationsDysfunctionMicroalbuminuriaRenalDiagnosisMorbidity and mortaInjectionsPreventionMortalityMETHODSChronicMetabolic SyndromeEndocrinologyBlood glucose2002CarotidMitochondrialInflammatoryCell in the pancreasPatients with typeCommonGlomerularSystemicPathologyRiskMechanismsUrinaryMarkedlyDisease
Retinopathy16
  • The prevalence of increased urinary albumin excretion (UAE) (micro- and macroalbuminuria) and its association with diabetic retinopathy (DR) (evaluated by fluorescent angiography), coronary heart disease (CHD), and various related risk factors were studied in 320 type 2 diabetic patients. (nih.gov)
  • We conclude that increased UAE is associated to a greater frequency of retinopathy and CHD in type 2 diabetic patients. (nih.gov)
  • Cheiroarthropathy is linked with more serious microvascular complications of diabetes eg retinopathy, nephropathy and neuropathy, so diagnosis is important. (iddt.org)
  • The IGF system has been associated with development and progression of diabetic retinopathy. (diabetesjournals.org)
  • We examined whether a simple measurement of the IGF system (serum total IGF-I) correlated with progression of diabetic retinopathy in pregnancy in type 1 diabetes. (diabetesjournals.org)
  • Pregnancy is a prominent risk factor for the development and progression of retinopathy in women with type 1 diabetes. (diabetesjournals.org)
  • However, after it was shown that pituitary ablation could halt the progression of proliferative diabetic retinopathy, increased focus has been put on the hormonal changes with growth-stimulating potential that accompanies pregnancy ( 1 ). (diabetesjournals.org)
  • Although some regression of nonproliferative retinopathy occurs after delivery, new cases with progression of retinopathy during pregnancy have been reported with a prevalence ranging between 20 and 85% ( 3 - 5 ). (diabetesjournals.org)
  • The aim of the present study was to examine the correlation between serum IGF-I and progression of retinopathy in diabetic pregnancy in 103 pregnant women with type 1 diabetes. (diabetesjournals.org)
  • The women were scheduled for ophthalmologic examination, including visual acuity testing and fundus photography, before pregnancy, once in each trimester, and 4 months after birth, according to the principles defined in the Early Treatment for Diabetic Retinopathy Study ( 6 ). (diabetesjournals.org)
  • Diabetic retinopathy (DR), one of the leading causes of blindness and vision impairment, is suggested to exhibit functional and structural changes in retinal neurons as the earliest manifestation, which could be used to predict the progression of related angiopathy. (biomedcentral.com)
  • Patients with diabetic retinopathy (DR) comprised 68% of the group with CIMT ≥1.0 mm, while they were 28% of the group without CIMT thickening ( P =0.003). (e-enm.org)
  • This publication is dedicated to the application of a complex of peptide bioregulators being highly effective in treatment of different retinal diseases (diabetic retinopathy, pigment retinitis, age-related macular degeneration etc. (antiaging-peptides.com)
  • Among the most frequent retinal diseases there are age-related macular degeneration, hereditary retinal degenerations (including retinitis pigmentosa), complicated myopia, diabetic retinopathy. (antiaging-peptides.com)
  • Although diabetic nephropathy, neuropathy and retinopathy are the most common microvascular complications of hyperglycemia, it also affects choroid plexus. (scialert.net)
  • Long-term complications from high blood sugar can include heart disease , strokes , diabetic retinopathy where eyesight is affected, kidney failure which may require dialysis , and poor circulation of limbs leading to amputations . (thediabeticpharmacist.com)
Nephropathy5
  • Diabetic nephropathy (DN) is one of the most serious complications of DM. (biomedcentral.com)
  • Protective Effects of Lithospermic Acid B on Diabetic Nephropathy in OLETF Rats Comparing with Amlodipine and Losartan. (e-dmj.org)
  • We examined the effects of LAB on the prevention of diabetic nephropathy compared with amlodipine, a calcium channel blocker, and losartan, an angiotensin receptor blocker, in Otsuka Long-Evans-Tokushima Fatty (OLETF) rats, an animal model of type 2 diabetes. (e-dmj.org)
  • CONCLUSION: These results suggest that LAB has beneficial effects on the diabetic nephropathy in OLETF rats by decreasing oxidative stress and inflammation as potent as losartan. (e-dmj.org)
  • Activation of NF-kappaB and AP-1 in Peripheral Blood Mononuclear Cells Isolated from Patients with Diabetic Nephropathy. (e-dmj.org)
Pathogenesis4
  • in particular, oxidant stress has been implicated in the pathogenesis of diabetic angiopathies ( 7 ). (diabetesjournals.org)
  • Recent studies have shown that diabetic microangiopathies are associated with macroangiopathies and suggest that microangiopathies may have a prominent role in the pathogenesis of microangiopathy development [ 2 ]. (e-enm.org)
  • Connective Tissue Growth Factor (CTGF) has recently been shown to be over-expressed in kidney, myocardium and aorta in diabetic animals, implicating CTGF role in the pathogenesis of both microvascular and macrovascular diabetic complications ( Brownlee, 2001 ). (scialert.net)
  • Moreover, NGFs and receptors are also expressed in retina and renal mesangial cells, suggesting their possible role in the common pathogenesis of diabetic microvascular complications. (e-dmj.org)
Ketoacidosis6
Hypertension6
  • Hypertension and cerebral amyloid angiopathy (CAA) are the most common causes of primary ICH, but the mechanism of hemorrhage in both conditions is unclear. (nature.com)
  • In primary ICH, hypertension is thought to be the underlying cause in 65% of cases, followed by cerebral amyloid angiopathy (CAA). (nature.com)
  • Retina is as a rule damaged in case of the following diseases: hypertension, diabetes mellitus, renal insufficiency etc. (antiaging-peptides.com)
  • The smaller deeper vessels that are the culprits of lacunar infarcts, such as the lenticulostriate arteries, are more often affected by hypertension and diabetes than by thromboses. (statpearls.com)
  • Prevalence of IGFBP3, NOS3 and TCF7L2 polymorphisms and their association with hypertension: a population-based study with Brazilian women of African descent. (cdc.gov)
  • Many people with hypertension are either diabetic or pre-diabetic and have elevated insulin levels due to insulin resistance. (thediabeticpharmacist.com)
Glycemic control6
  • Survey data (response rate 86.2%) and administrative databases were used to assess diabetes severity, glycemic control, quality of life, microvascular and macrovascular risks and complications, preventive care, utilization, and perceptions of diabetes. (healthpartners.com)
  • RESULTS: Compared to those aged 45-64 years (N = 627), those 65 and older (N = 482) had better glycemic control, better health-related behaviors, and perceived less adverse impacts of diabetes on their quality of life despite longer duration of diabetes and a prevalence of cardiovascular disease twice that of younger patients. (healthpartners.com)
  • [ 5 ] Benefits of tight glycemic control include not only continued reductions in the rates of microvascular complications but also significant differences in cardiovascular events and overall mortality. (medscape.com)
  • Also, the use of systemic steroids can worsen glycemic control in diabetic patients. (ejao.org)
  • Also, we evaluated the clinical features of SSNHL in diabetic patients including the laboratory data which are known to be related to systemic inflammation and glycemic control. (ejao.org)
  • Long term diabetes and poor glycemic control are the most important risk factors for DN development ( DCCT Research Group, 1993 ). (scialert.net)
Micro-angiopathy2
  • The occurrence of diabetic foot is closely related to micro-angiopathy, micro-thrombosis in the lower limb, which may predate the presentation of diabetic foot. (biomedcentral.com)
  • However, very little data are available on IS of circulating cells of MetS patients although clinical data show that inhibited mTOR, with specific inhibitors such as Serolimus or Everolimus after kidney transplantation, significantly increase the presence of de novo thrombotic micro-angiopathy with artery lesion characterized by intimal cell proliferation, necrosis and narrowed lumen. (biomedcentral.com)
Incidence4
  • Diabetes prevention, detection and management should be prioritized in any attempt to reduce the current incidence of amputation in Lebanon. (who.int)
  • Yet the rising was to highlight the major burden of reason) for surgery according to the incidence of diabetes and vascular dis- amputation and to set standards for patient's hospital record. (who.int)
  • The prevalence and incidence of dementia with Lewy bodies: a systematic review of population and clinical studies. (gov.gy)
  • The Incidence & Prevalence Database (IPD) is the most efficient way to look at the world's epidemiology data. (tdrdata.com)
Hyperglycemia4
  • Diabetes mellitus (referred to as diabetes below) is a chronic progressive disease characterized by uncontrolled hyperglycemia and a series of metabolic disorders. (biomedcentral.com)
  • Diabetes is a methabolic disease characterized by hyperglycemia, with high morbidity and mortility worldwide. (scialert.net)
  • Diabetic microvasular complications, which are considered as an important group of hyperglycemia imperfections, caused by increased endothelial permeability and can progress to severe impairments in several organs. (scialert.net)
  • Although all diabetic cells are exposed to elevated levels of plasma glucose, hyperglycemic damage is limited to those cell types that are unable to down regulate glucose transport into the cell (e.g., endothelial cells), leading to intra-cellular hyperglycemia ( Brownlee, 2001 ). (scialert.net)
Clinical14
  • The International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) code for type 1 diabetes without complications is E10.9. (medscape.com)
  • This clinical study enrolled 163 type 2 diabetes mellitus (T2DM) patients, who were divided into the diabetes with DF (84 cases) group, diabetes with no DF (79 cases) group. (biomedcentral.com)
  • Angle α, k-value and fibrinogen have clinical significance on the risk of occurrence and development of diabetic foot, which can contribute to early diagnosis and early clinical intervention in DF. (biomedcentral.com)
  • A large clinical study found that peripheral vascular disease (PAD) in patients with T2DM is a serious complication. (biomedcentral.com)
  • A large clinical study found that the prevalence of PAD in patients with T2DM was 23.5% [ 2 ], and diabetic patients with combined PAD are more likely to develop ulceration and gangrene of the limb, significantly increasing the risk of amputation. (biomedcentral.com)
  • Updated clinical guidelines "Standards of specialized diabetes care", 9th Edition. (orscience.ru)
  • Dr. Crandall is Professor of Medicine at Albert Einstein College of Medicine, where she is director of the Diabetes Clinical Trials Unit and a principal investigator for several NIH sponsored clinical trials, including the Diabetes Prevention Program Outcome Study (for which she holds several national leadership positions, including Executive Committee membership) and the Glycemia Reduction Approaches in Diabetes (GRADE) study. (einsteinmed.edu)
  • See Clinical Findings in Diabetes Mellitus, a Critical Images slideshow, to help identify various cutaneous, ophthalmologic, vascular, and neurologic manifestations of DM. (medscape.com)
  • The recommendations can be accessed at American Diabetes Association DiabetesPro Professional Resources Online, Clinical Practice Recommendations - 2015. (medscape.com)
  • This study aimed to evaluate the clinical features and the clinical factors associated with prognosis of sudden sensorineural hearing loss (SSNHL) in diabetic patients. (ejao.org)
  • Therefore, we conducted a retrospective review to evaluate the clinical factors associated with prognosis and compare the efficacy of simultaneous and sequential systemic steroid and ITD treatment in diabetic patients with SSNHL. (ejao.org)
  • The present clinical case is that of a man with the renal complications of scleroderma and the difficulties of the treatment even in the developed countries like France. (scirp.org)
  • Early detection of complications through a minimal clinical examination supplemented with paraclinic tests has proved necessary. (scirp.org)
  • In the clinical 2 practice this preparation turned out to be highly effective in the treatment of the aftereffects of retinal veins thrombosis, glaucoma, haemorrhagic retinopathies, retinal sun and laser burns and many other diseases. (antiaging-peptides.com)
Microvascular disease1
  • Growth hormone (GH) exerts many of its effects via the synthesis and release of IGF-I. IGF-I has been variably associated with diabetic microvascular disease, and a transient rise in IGF-I has been reported in the early phase of neovascularization of the retina ( 2 ). (diabetesjournals.org)
Mellitus Type6
Abstract1
  • ABSTRACT Chronic diseases such as diabetes and vascular disease are a major public health problem in Lebanon, where primary care is not well developed. (who.int)
T2DM3
Etiology1
  • Here we briefly reviewed the characteristic and etiology of these complications emphasizing on cerebrospinal fluid. (scialert.net)
Neuropathy7
  • Amyotrophy A type of diabetic neuropathy that causes muscle weakness and wasting. (wikipedia.org)
  • It is usually painless but numbness and pain may be present if there is also neuropathy or angiopathy of the hand. (iddt.org)
  • A type of neuropathy resulting in pain, weakness and/or wasting in the muscles. (diabetes.org)
  • CAN was defined as the presence of at least two abnormal tests or an autonomic neuropathy points ≥2. (e-enm.org)
  • Cardiac autonomic neuropathy (CAN) is one of the most common complications of diabetes, and represents a significant cause of morbidity and mortality in diabetic patients. (e-enm.org)
  • In vivo corneal confocal microscopy (IVCCM) is being recognized as a non-invasive, early diagnostic tool for diabetic neuropathy, for it provides a clear image of corneal subbasal nerve plexus in detail. (e-dmj.org)
  • Nerve growth factors (NGF) are believed to regulate peripheral and central nervous system, neuronal differentiation, and regeneration of damaged nerves, and their role in diabetic neuropathy is being emphasized these days. (e-dmj.org)
Comorbidity1
  • The most pronounced deterioration of diurnal arterial stiffness indicators in the group of comorbid patients with EAH and SН, as well as the excess of vascular age over chronological and reliable correlation with the comorbidity index, revealed during the study, suggests an assessment of these indicators in patients with cardioendocrine pathology to assess the true risk cardiovascular complications and the selection of adequate therapy. (orscience.ru)
Albumin excretion1
  • Aassociations between carotid atherosclerosis and both urine albumin excretion (UAE) and glomerular filtration rate (GFR) in diabetic patients have been investigated, but these studies showed only inconsistent results [ 5 , 13 , 14 ]. (e-enm.org)
Cerebral1
  • Less frequently, hemorrhagic strokes can also be due to angiopathies, which can be diagnosed with a cerebral angiogram. (statpearls.com)
Progression4
  • Research suggests that fibrinogen (Fib) concentrations are used to assess the occurrence and severity of diabetic foot (DF) and to monitor the progression of diabetic foot in patients. (biomedcentral.com)
  • Therefore, finding indicators that predict the risk of occurrence and progression of diabetic foot and early intervention can help improve the quality of life. (biomedcentral.com)
  • There is a lack of uniform quantitative standards for biomarkers that predict the risk of diabetic foot occurrence and progression. (biomedcentral.com)
  • Progression of mild cognitive impairment to dementia in clinic- vs community-based cohorts treatment type 2 diabetes order flexeril 15mg with visa. (gov.gy)
Obesity2
Amputations1
  • La prévention du diabète, son dépistage et sa prise en charge doivent devenir prioritaires afin de tenter de réduire l'incidence actuelle des amputations au Liban. (who.int)
Dysfunction3
  • While neural function and survival rely on proper mitochondrial function, and a growing body of literature has supported the role of mitochondrial dysfunction in the development of DR, how diabetes affects mitochondrial function in retinal tissue remains elusive. (biomedcentral.com)
  • 2. Schmidt AM, Crandall J , Hori O, Cao R and Lakatta E. Elevated plasma levels of vascular cell adhesion molecule-1 (VCAM-1) in diabetic patients with microalbuminuria: a marker of vascular dysfunction and progressive vascular disease. (einsteinmed.edu)
  • Recommendations of the Polish Society of Endocrinology and Polish Diabetes Association for the management of thyroid dysfunction in type 1 and type 2 diabetes = Zalecenia Polskiego Towarzystwa Endokrynologicznego oraz Polskiego Towarzystwa Diabetologicznego dotycz ce diagnostyki i leczenia zaburze funkcji tarczycy w cukrzycy typu 1 i 2. (edu.pl)
Microalbuminuria1
  • Although in all diabetic patients, GFR is initially normal or mildly elevated with no histological alterations, it progresses to produce thick glomerular basement membrane and expand to mesangial, followed by high glomerular capillary pressure and microalbuminuria. (scialert.net)
Renal1
  • Opdivo and Opdivo -based combinations are important treatment options with established benefit across many cancer types, including melanoma, renal cell carcinoma, non-small cell lung cancer, mesothelioma, head and neck cancer, and bladder cancer, as well as esophageal, gastric, and gastroesophageal junction cancers. (bms.com)
Diagnosis2
  • Study subjects were a random sample of 1109 adults age 45 and over with an established diagnosis of diabetes using a diabetes identification method with estimated sensitivity 0.91 and positive predictive value 0.94. (healthpartners.com)
  • The International Working Group on the Diabetic Foot has developed guidelines for the diagnosis of the diabetic foot. (biomedcentral.com)
Morbidity and morta1
  • The rapidly increasing prevalence of diabetes and its related complications do not only affect the morbidity and mortality of patients, but also bring huge medical and economic burdens to society worldwide. (biomedcentral.com)
Injections3
  • Most require 2 or more injections of insulin daily, with doses adjusted on the basis of self-monitoring of blood glucose levels. (medscape.com)
  • Simultaneous intratympanic dexamethasone (ITD) injections with systemic steroid did not confer an additional hearing gain or an earlier recovery rate in diabetic patients with SSNHL. (ejao.org)
  • Simultaneous ITD injections to improve hearing recovery in diabetic patients with SSNHL seems unnecessary. (ejao.org)
Prevention3
  • The influence of age on the effects of lifestyle modification and metformin in prevention of diabetes. (einsteinmed.edu)
  • Adherence to preventive medication: predictors and outcomes in the Diabetes Prevention Program. (einsteinmed.edu)
  • In Lebanon, the preva- could be achieved in order to support main indication was recorded for each lence of type 2 diabetes was 13.1% for the development of programmes for patient from either trauma, diabetes, those aged 30+ years in 1994-95 [2] amputation prevention and care. (who.int)
Mortality1
  • Vascular complications are responsible for the excess mortality associated with diabetes ( 1 ), and impaired endothelium-dependent vasodilation has been described in humans and in animal models of the disease ( 2 - 6 ). (diabetesjournals.org)
METHODS1
  • METHODS: IVCCM, nerve conduction velocity (NCV), and serum, urine, and tear samplings were done to 42 diabetic patients. (e-dmj.org)
Chronic3
  • Type 1 diabetes is a chronic illness characterized by the body's inability to produce insulin due to the autoimmune destruction of the beta cells in the pancreas. (medscape.com)
  • previous transmission electron microscopic studies have demonstrated glomerular basement membrane (gbm) thickening and mesangial matrix (mm) expansion in chronic stages of diabetes. (liverpool.ac.uk)
  • Type 2 diabetes is typically a chronic disease associated with a ten-year-shorter life expectancy. (thediabeticpharmacist.com)
Metabolic Syndrome2
  • Diabetes & metabolic syndrome 0 13 (2): 1317-1320. (cdc.gov)
  • While most cases of HCC are caused by hepatitis B virus (HBV) or hepatitis C virus (HCV) infections, metabolic syndrome and nonalcoholic steatohepatitis (NASH) are rising in prevalence and expected to contribute to increased rates of HCC. (bms.com)
Endocrinology1
  • Endocrinology 2018 Conference is based on the theme of Reconnoitering the Challenges Concerning Endocrinology and Diabetes Research . (endocrineconferences.com)
Blood glucose3
20021
Carotid3
  • Patients with CAN comprised 51% of the group with ≥2 carotid plaques, while they were 23% of the group with ≤1 carotid plaque ( P =0.014). (e-enm.org)
  • Carotid atherosclerosis as estimated by carotid intima-media thickness (CIMT) and plaques is considered to reflect an early stage of atherosclerotic disease and is therefore used as a surrogate marker for diabetic macroangiopathies [ 6 - 8 ]. (e-enm.org)
  • So far, studies on the relationship between diabetic microangiopathies and carotid atherosclerosis have yielded inconsistent results. (e-enm.org)
Mitochondrial2
  • This study primarily aimed to investigate mitochondrial functional changes in a diabetic rodent model. (biomedcentral.com)
  • Our longitudinal data suggest that diabetes-induced functional deterioration and morphological changes were accompanied by reduced mitochondrial function in the retina of db/db mice. (biomedcentral.com)
Inflammatory1
Cell in the pancreas2
Patients with type1
Common5
  • The most common cause would be insulin resistance, usually from type 2 diabetes mellitus. (wikipedia.org)
  • Diabetes mellitus (DM) is a common disease in the modern society. (biomedcentral.com)
  • Common genetic variants and pathways in diabetes and associated complications and vulnerability of populations with different ethnic origins. (cdc.gov)
  • Liver cancer is the fourth most frequent cause of cancer death worldwide and hepatocellular carcinoma (HCC), the most common type of liver cancer, is the fastest rising cause of cancer-related death in the United States. (bms.com)
  • CONCLUSION: Our results provide a possibility of using novel tools, IVCCM and NGF, as common diagnostic tools for diabetic microvascular complications, but it should be followed by a large population study. (e-dmj.org)
Glomerular1
  • sem studies of acellular glomerular basement membrane in human diabetic glomerulopathy. (liverpool.ac.uk)
Systemic2
  • Additionally, microvascular problems in diabetic patients can affect the delivery and efficacy of systemic steroid in the cochlea [ 6 , 7 ]. (ejao.org)
  • Given this, systemic steroid use for SSNHL in diabetic patients may lead to poorer outcomes than are observed in those without DM [ 8 , 9 ]. (ejao.org)
Pathology1
  • Results Chemical substance notoginseng nanoparticles is effective in reducing the particular contents of TNF-α and also IL-6 in solution while increasing the particular appearance of IL-2 inside rodents with craniocerebral harm.We all present an explanation involving approach to wide open midline extraperitoneal medical procedures for your treatments for retroperitoneal pathology. (fak-signal.com)
Risk4
  • Precisely what causes it is not fully known, but diabetics have increased risk of both heart attack and stroke, so some of the tissue damage diabetes produces may be involved. (wikipedia.org)
  • Screening for type 1 diabetes in asymptomatic low-risk individuals is not recommended. (medscape.com)
  • [ 2 ] However, in patients at high risk (eg, those who have first-degree relatives with type 1 diabetes), it may be appropriate to perform annual screening for anti-islet antibodies before the age of 10 years, along with 1 additional screening during adolescence. (medscape.com)
  • However, most of the relevant studies have focused on the analysis of risk factors associated with the diabetic foot and comprehensive management. (biomedcentral.com)
Mechanisms2
  • This paper highlights the underlying pharmacological mechanisms of the anti-diabetic effects of ginsenosides. (frontiersin.org)
  • Although the precise underlying mechanisms linking the diabetic microangiopathies and macroangiopathies are unclear, some evidence suggests that the effects of microangiopathies may be linked to subclinical atherosclerosis [ 3 - 5 ]. (e-enm.org)
Urinary1
  • 60 mL/min/1.73 m 2 for 3 months or more) or albuminuria (urinary albumin-to-creatinine ratio ≥ 30 mg/g) in the setting of DM [ 2 ], is one of the most serious complications of DM. (biomedcentral.com)
Markedly1
  • Despite the high prevalence of diabetes in developed countries, a recent report has indicated that the prevalence of diabetes is currently increasing most markedly in low- and middle-income countries [ 2 ]. (biomedcentral.com)
Disease1