AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth CareGeographicals
Lymphoproliferative DisordersEpstein-Barr Virus InfectionsPrevalenceHerpesvirus 4, HumanOrgan TransplantationTransplantationAutoimmune Lymphoproliferative SyndromeLeukemia, Hairy CellGiant Lymph Node HyperplasiaLymphoma, B-CellLymphomaB-LymphocytesLeukemia, Lymphocytic, Chronic, B-CellLymphomatoid PapulosisHerpesviridae InfectionsLeukemia, ProlymphocyticAntigens, CD30LymphocytosisImmunosuppressive AgentsKidney TransplantationLymphoma, T-CellWaldenstrom MacroglobulinemiaImmunophenotypingLymphoma, T-Cell, CutaneousLymphomatoid GranulomatosisPseudolymphomaLeukemia, B-CellAntibodies, Monoclonal, Murine-DerivedImmunocompromised HostPostoperative ComplicationsLymphoma, Non-HodgkinCryoglobulinemiaTransplantsImmunosuppressionHodgkin DiseaseBipolar DisorderT-LymphocytesFatal OutcomeAntigens, CD20Risk FactorsTumor Virus InfectionsMycosis FungoidesLeukemia, LymphoidImmunoblastic LymphadenopathyLymphatic DiseasesMental DisordersLymph NodesAntibodies, MonoclonalEpstein-Barr Virus Nuclear AntigensPolymerase Chain ReactionSplenomegalyAntigens, CD5Anxiety DisordersMood DisordersAutoimmune DiseasesRetrospective StudiesClone CellsLeukemia, Large Granular LymphocyticBurkitt LymphomaParaproteinemiasLymphoma, Large B-Cell, DiffuseAntigens, CDCladribineParaphimosisFlow CytometryLung TransplantationLymphocytesHeart TransplantationLeukemia, T-CellHerpesvirus 8, HumanLiver TransplantationTransplantation, HomologousDNA, ViralTreatment OutcomeLymphoma, Large-Cell, AnaplasticLymphoma, Mantle-CellSplenic NeoplasmsLeukemia, Prolymphocytic, T-CellInfectious MononucleosisViral Matrix ProteinsTime FactorsLymphocyte ActivationDiagnostic and Statistical Manual of Mental DisordersImmunologic Deficiency SyndromesBiopsyCross-Sectional StudiesFollow-Up StudiesCryoglobulinsNeoplasms, Plasma CellLymphoma, AIDS-RelatedLeukemiaParaproteinsSplenectomyImmunoglobulin Heavy ChainsSkin NeoplasmsMyeloproliferative DisordersGene Rearrangement, gamma-Chain T-Cell Antigen ReceptorLymphoma, Primary Cutaneous Anaplastic Large CellPhenotypeBone Marrow Transplantation
PosttransplantInfectionMultiple myelomaPatientsClinicalKidney transplantationPTLDOverall prevalenceMycosis fungoidesRarest disordersAutoimmune disorderInfectiousIncidenceHepatitisDiseaseAdultsThrombocytopeniaRituximabLymphomatoidInfectionsBenignNeurologicalDiagnosisAutosomalMonoclonalLymphomasDiseasesDeficiencySplenomegalyMethodsViralCharacteristicsSymptomsSyndromeExposureSickleAbnormalCasesPrimaryHighHereditaryPopulationRareOccurPesticidesDifferences
Posttransplant1
  • When death in the absence of HBV-RS was considered as the competing risk, the univariate and multivariate regression analyses showed that several factors were independently associated with the development of HBV-RS, including anti-HCV seronegativity, histological subtype of posttransplant lymphoproliferative disorders, ≥6 cycles of rituximab therapy, and succeeding hematopoietic stem cell transplantation. (nycu.edu.tw)
Infection6
  • Conclusion: There was no association between hepatitis C virus infection and lymphoproliferative disorder in our population. (aku.edu)
  • However, further studies are required from this region to establish any causal relationship between hepatitis C virus infection and lymphoproliferative disorder. (aku.edu)
  • Prevalence of hepatitis C virus infection in patients with lymphoproliferative disorders in Southern Turkey. (acibademfamicord.com)
  • Aside from the economic crisis, COVID-19 has caused substantial issues for patients with mental and neurological disorders due to their increased susceptibility to infection. (grandviewresearch.com)
  • Lower prevalence of BK virus infection in African American renal transplant recipients: a prospective study. (mcw.edu)
  • In some areas where HTLV-I infection is endemic, prevalence rates as high as 15% have been reported in the general population. (cdc.gov)
Multiple myeloma2
Patients24
  • Methods: A case control prospective study was performed on 143 patients with lymphoproliferative disorders and 29 patients with non-hematological malignancies were taken as controls. (aku.edu)
  • Five percent patients with lymphoproliferative disorders and 3.4% with non-hematological malignancies were positive for anti HCV. (aku.edu)
  • In a hospital-based, retrospective, case-control study in 20112012, adult cases of lymphoproliferative disorders (n = 130) were recruited from outpatient clinics in Menoufia, Egypt, while controls (n = 130) were age- and sex-matched fracture patients. (who.int)
  • Kyle studied the prevalence of myeloma in the population as a whole (not clinic patients) in Olmsted County, Minnesota. (wikipedia.org)
  • The prevalence of ITP in non-Hodgkin's lymphoma patients is lower compared to autoimmune hemolytic anemia, occurring in only up to 1.8% of cases ( 3 ). (spandidos-publications.com)
  • CD30+ LPD prevalence in African American (AA)/Black patients is lower compared to White patients. (nextstepsinderm.com)
  • 2012, adult cases of lymphoproliferative disorders ( n = 130) were recruited from outpatient clinics in Menoufia, Egypt, while controls ( n = 130) were age- and sex-matched fracture patients. (who.int)
  • To avoid immunosuppression in chronic lymphocytic leukaemia (CLL), there is an association between pesti- these patients all cases were selected non-Hodgkin lymphoma (NHL), cide exposure and lymphoproliferative before initiation of chemotherapy. (who.int)
  • Background The prevalence of peripheral neuropathy in patients with Sjögren syndrome remains unclear owing to conflicting results in the published series, with numbers ranging from 2% to over 60% of Sjögren syndrome patients. (bmj.com)
  • Summary This study points toward a decrease in the incidence of colorectal cancer in ulcerative colitis patients, but an increase in the incidence of lymphoproliferative disorders and nonmelanoma skin cancers with the use of immunosuppressive medications in IBD. (medscape.com)
  • The prevalence of pulmonary involvement in pSS patients varies widely [ 4 ]. (ersjournals.com)
  • When pulmonary involvement is investigated systematically, prevalence ranges between 43% and 75% [ 9 ] and on HRCT of the chest abnormalities are found in 34-50% of the patients [ 10 ]. (ersjournals.com)
  • The rising number of patients with immunodeficiency disorders is the primary cause for the development of IVIG preparations. (grandviewresearch.com)
  • The overall prevalence of KS in the U.S. was as high as 30% among patients with AIDS prior to the advent of effective antiretroviral therapy (ART). (hiv.gov)
  • Brain "fog" characterizes patients with autism spectrum disorders (ASDs), celiac disease, chronic fatigue syndrome, fibromyalgia, mastocytosis, and postural tachycardia syndrome (POTS), as well as "minimal cognitive impairment," an early clinical presentation of Alzheimer's disease (AD), and other neuropsychiatric disorders. (aad.org)
  • The Pierre Fabre Group is also exploring rare diseases in the field of oncology : the French pharmaceutical company and the California-based biotech Atara Biotherapeutics (partners since 2021) announced in December that they had obtained MA for the treatment of relapsed or refractory Epstein-Barr virus-positive post-transplant lymphoproliferative disease (EBV+ PTLD) in patients aged over two who had received at least one previous treatment. (pierre-fabre.com)
  • Eight patients died, including 4 of the 9 patients with myeloproliferative disorder--2 from a combination of respiratory failure due to COP and graft-versus-host disease. (nih.gov)
  • However, Candell, Chalom and colleagues recently reported that, in a retrospective study, although the prevalence of uveitis was lower in ANA-negative patients compared with ANA-positive patients, ocular complications were more common in children with uveitis who were ANA negative. (uveitis.org)
  • Pia Raanani Introduction: Data regarding the prevalence of paraproteinemia in patients with chronic myeloid leukemia (CML) are lacking. (karger.com)
  • Riegler G, Carratu R, Tartaglione M, Morace F, Manzione R, Arimoli A. Prevalence and relative risk of malignancy in relatives of inflammatory bowel disease patients and control subjects. (familialcancerdatabase.nl)
  • Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. (familialcancerdatabase.nl)
  • Although many life-threatening causes such as malignancies or infections have been described, most patients who report persistent night sweats in the primary care setting do not have a serious underlying disorder. (aafp.org)
  • Night sweats are a common experience, with a prevalence of up to 41% among primary care patients. (aafp.org)
  • A systematic review found that the cross-sectional prevalence of night sweats ranges from 10% to 41% in the primary care setting, with the highest prevalence occurring in patients between 41 and 55 years of age. (aafp.org)
Clinical7
  • Lambert-Eaton myasthenic syndrome (LEMS) is a rare presynaptic disorder of neuromuscular transmission in which quantal release of acetylcholine (ACh) is impaired, causing a unique set of clinical characteristics, which include proximal muscle weakness, depressed tendon reflexes, posttetanic potentiation, and autonomic changes. (medscape.com)
  • Yavuz S., Disel U., Tanrıverdi K., Sahin B., Burgut R. Anti-HCV and HCV-RNA prevalence and clinical correlations in cases with Non- Hodgkin Lymphomas. (acibademfamicord.com)
  • This study aimed to conduct a pooled estimate of HTLV-1 prevalence among pregnant women in Nigeria to quantify its clinical burden and public health implications. (e-cep.org)
  • To develop evidence-based recommendations for the use of methotrexate in daily clinical practice in rheumatic disorders. (bmj.com)
  • Ten clinical questions concerning the use of methotrexate in rheumatic disorders were formulated. (bmj.com)
  • Through his clinical trial work, he also provided access to advanced treatments that are being tested in the treatment of these disorders. (rochester.edu)
  • Initial management consisted of en una paciente con topical corticosteroids and oral antihistamines with little clinical response. (bvsalud.org)
Kidney transplantation1
PTLD1
  • differences in the epidemiology of post-transplant lymphoproliferative disease (ptld) between adult and paediatric kidney transplant recipients remain unclear. (liverpool.ac.uk)
Overall prevalence1
  • The overall prevalence of inflammatory bowel disease (IBD) is approximately 0.4% in Europeans and North Americans. (medscape.com)
Mycosis fungoides1
  • 1 CD30+ LPD is the second most common group of cutaneous T-cell lymphomas (CTCL) after mycosis fungoides (MF) and is regarded as an indolent lymphoproliferative disorder 1 LyP typically manifests clinically as a recurrent eruption of papules and nodules with variable central ulceration, scale or crust that resolve spontaneously within several weeks and may result in hyperpigmentation, hypopigmentation, and scarring. (nextstepsinderm.com)
Rarest disorders2
  • Dermatology is the branch of medicine that has the rarest disorders worldwide. (pierre-fabre.com)
  • The incidence of PIDs varies greatly from about 1:500 births with selective IgA deficiency to only a few known cases for the rarest disorders. (lu.se)
Autoimmune disorder2
  • Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated destruction and impaired production of platelets, with isolated thrombocytopenia. (spandidos-publications.com)
  • Adenopathy may suggest a lymphoproliferative, infectious, or autoimmune disorder. (msdmanuals.com)
Infectious2
Incidence1
Hepatitis1
Disease8
  • No evidence of bone lesions, anemia, hypercalcemia, or chronic kidney disease related to the paraprotein, and No evidence of another B-cell proliferative disorder. (wikipedia.org)
  • Lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (ALCL) comprise a disease spectrum known as primary cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ LPD). (nextstepsinderm.com)
  • Although several studies have focused on the peripheral nerve manifestations of Sjögren syndrome, two issues remain contentious: the prevalence of peripheral neuropathy, with a reported range between 2 and 60%, 6 13 18-29 and the stage of the disease in which peripheral neuropathy is most commonly manifested. (bmj.com)
  • Pulmonary involvement in pSS includes interstitial lung disease (ILD) and airway disease, together with lymphoproliferative disorders. (ersjournals.com)
  • Gaucher Disease Gaucher disease is a sphingolipidosis, an inherited disorder of metabolism, resulting from glucocerebrosidase deficiency, causing deposition of glucocerebroside and related compounds. (msdmanuals.com)
  • HHV-8 is etiologically associated with all forms of Kaposi sarcoma (KS) including classic, endemic, transplant-related, and AIDS-related, as well as rare neoplastic disorders (primary effusion lymphoma [PEL] and solid organ variants) and the lymphoproliferative disorder known as multicentric Castleman's disease (MCD). (hiv.gov)
  • The prognosis is excellent with idiopathic cases but more guarded especially when COP is associated with lymphoproliferative or connective tissue disease. (nih.gov)
  • it is updated every other year to include new disorders or disease-causing genes. (springer.com)
Adults1
  • Because of the relatively high prevalence of anti-HBc seropositivity in unvaccinated HBsAg-seronegative adults in an HBV hyperendemic area, we aimed to investigate additional factors influencing the development of rituximab-associated HBV-RS. (nycu.edu.tw)
Thrombocytopenia3
  • There are multiple mechanisms and differential diagnosis includes: artifactual thrombocytopenia, accelerated platelet destruction (intra- or extra-corpuscular anomalies), deficient production (bone marrow failure, disordered proliferation or thrombopoietin deficiency), and abnormal distribution (disorders associated with splenomegaly or dilution in massive transfusions) ( 1 ). (spandidos-publications.com)
  • Some of the many underlying disorders that are associated with immune thrombocytopenia are also lymphoproliferative disorders. (spandidos-publications.com)
  • Autoimmune disorders typically develop several years later, most frequently as a combination of hemolytic anemia and thrombocytopenia, also called Evans syndrome. (medlineplus.gov)
Rituximab1
  • Humanized anti-CD20 monoclonal antibody (Rituximab) treatment for post-transplant lymphoproliferative disorder. (mcw.edu)
Lymphomatoid1
  • Lymphomatoid papulosis (LyP) is a CD30+ T-cell lymphoproliferative disorder (LPD) presenting as a recurrent eruption of papules and nodules which resolve spontaneously. (nextstepsinderm.com)
Infections1
Benign1
Neurological1
  • A very rare and atypical form of Ch diak-Higashi syndrome (CHS), a genetic disorder characterized by partial oculocutaneous albinism, severe immunodeficiency, mild bleeding, neurological dysfunction and lymphoproliferative disorder. (orpha.net)
Diagnosis1
  • Colonic biopsies diagnosed Epstein-barr virus-associated lymphoproliferative disorder, but the sample was inadequate for definitive diagnosis. (frontiersin.org)
Autosomal2
  • In most people with ALPS, including the majority of those with FAS gene mutations, this condition is inherited in an autosomal dominant pattern, which means one copy of an altered gene in each cell is sufficient to cause the disorder. (medlineplus.gov)
  • Hereditary angioedema is a rare autosomal dominant disorder, which is characterized by recurrent attacks of angioedema resulting from a deficiency of C1 esterase inhibitor enzyme [ 4 ]. (biomedcentral.com)
Monoclonal2
  • Monoclonal B-cell lymphocytosis (MBL) is a precursor lesion that can be screened for in apparently healthy people, allowing comparison of prevalence across different populations independently of health-care provision. (scilifelab.se)
  • The causes of non-hereditary angioedema are variable and include acquired C1 esterase inhibitor deficiency, which is a result of an auto-antibody to C1-INH, or generation of anti-idiotypic antibody to monoclonal immunoglobulins which occur in various B cell lymphoproliferative diseases and other malignancies [ 5 ]. (biomedcentral.com)
Lymphomas1
  • Interference with apoptosis allows cells to multiply without control, leading to the lymphomas that often occur in people with this disorder. (medlineplus.gov)
Diseases2
  • The growing geriatric population, rising prevalence of immunodeficiency diseases, increasing adoption of intravenous immunoglobulin (IVIG) treatments, and rising use of off-label indications are the key drivers of the market. (grandviewresearch.com)
  • Moreover, sedentary lifestyle habits, including consumption of saturated fats salt, & sugars, less physical activities, and high alcohol consumption have led to an increase in the prevalence of these diseases. (grandviewresearch.com)
Deficiency3
  • The rising prevalence of lifestyle-associated disorders such as obesity & antibody deficiency disorders are the factors expected to drive the growth. (grandviewresearch.com)
  • 1) Antibody deficiency disorders are defects in immunoglobulin-producing B cells . (lu.se)
  • In certain metabolic disorders ( ADA and PNP deficiency) enzyme substitution therapy can be applied. (lu.se)
Splenomegaly1
  • Splenomegaly is almost always secondary to other disorders. (msdmanuals.com)
Methods1
Viral1
  • Inoculation with a high dose strains of LMP1 transgenic mice vide a powerful tool in mechanistic of EBV caused a B-cell lymphopro- were established that express LMP1 studies on the role of individual viral liferative disorder in these mice, under the control of the immunoglob- genes in cancer. (who.int)
Characteristics1
  • We aimed to compare the prevalence and phenotypic characteristics of MBL in age-and-sex-matched populations from rural Uganda and the UK. (scilifelab.se)
Symptoms1
  • Most of the presenting symptoms result from the underlying disorder. (msdmanuals.com)
Syndrome1
  • Autoimmune lymphoproliferative syndrome (ALPS) is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). (medlineplus.gov)
Exposure1
Sickle1
  • Conceivably, the increased expression of "I" and "I" in sickle cell disorders, thalassemia and HbE and polycythemia vera might render the erythrocytes in these disorders more vulnerable to cold agglutinins and hemolysis. (ispub.com)
Abnormal1
  • PTLDs are a varied class of abnormal lymphoid growths, including both hyperplasias and neoplasias, that are histologically and genetically heterogeneous disorders hallmarked by an abnormal lymphoid cell proliferation. (medscape.com)
Cases2
Primary1
  • The rising prevalence of primary and acquired immunodeficiency illnesses including AIDS and X-linked hypogammaglobulinemia is projected to increase demand for immunoglobulin therapy during the forecast period. (grandviewresearch.com)
High2
  • We aim to generate county-level prevalence estimates, masked by national and state estimates, to identify counties with high PSA screening prevalence. (cdc.gov)
  • Emerging data demonstrating the high prevalence of TV in the general population and interactions between TV and HIV suggest that additional research efforts should be directed at determining the possible benefits of enhanced screening for this important pathogen. (paperzz.com)
Hereditary1
Population2
  • The prevalence in the general population is estimated between 0.02% and 2.7% [ 3 ], according to the diagnostic criteria used and the ethnic background of the population. (ersjournals.com)
  • HS usually presents after puberty with a global prevalence of 1% in the general population. (pressbooks.pub)
Rare1
  • More rare disorders can be also identified, such as pleural effusion, cysts or bullae. (ersjournals.com)
Occur3
  • Autoimmune disorders occur when the immune system malfunctions and attacks the body's own tissues and organs. (medlineplus.gov)
  • Less commonly, autoimmune disorders that affect other organs and tissues occur in people with ALPS. (medlineplus.gov)
  • that occur early in embryonic development in people with no history of the disorder in their family. (medlineplus.gov)
Pesticides1
  • RÉSUMÉ Étant donné l'utilisation largement répandue des pesticides en Égypte et l'incidence croissante de la leucémie et du lymphome, nous avons tenté d'évaluerl'exposition aux pesticides et d'autres variables sélectionnées en tant que facteurs de risque des maladies lymphoprolifératives (leucémie et lymphome non-hodgkinien). (who.int)
Differences1