• Methicillin-resistant Staphylococcus aureus (MRSA) with reduced vancomycin susceptibility (VISA, vancomycin-intermediate S. aureus ) has been reported from many countries. (cdc.gov)
  • We have studied 101 MRSA with reduced vancomycin susceptibility from nine countries by multilocus sequence typing (MLST) and characterization of SCC mec (staphylococcal chromosomal cassette mec ) and agr (accessory gene regulator). (cdc.gov)
  • Most isolates (88/101) belonged to two of the earliest MRSA clones that have global prevalence. (cdc.gov)
  • Increasing antimicrobial resistance in genetically distinct pandemic clones may lead to MRSA infections that will become increasingly difficult to treat. (cdc.gov)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a major problem around the world, causing hospital-acquired infections and, more recently, infections in the community ( 1 , 2 ). (cdc.gov)
  • Researchers have suggested that isolates of the New York/Japanese pandemic MRSA clone may be predisposed to become vancomycin resistant, perhaps because of loss-of-function mutations in the agr (accessory gene regulator) gene ( 11 ). (cdc.gov)
  • ABSTRACT This is the largest Libyan study to date to investigate the prevalence and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) among health care workers in Tripoli, Libya. (who.int)
  • BSAC), using cefoxitin, as described by aureus (MRSA) first emerged as a no- Four major different hospitals were in- Andrews [16], and the presence of PB- socomial pathogen in the early 1960s cluded in this study and were assigned P2a was detected by latex agglutination and it continues to be a significant the following abbreviations: A, B, C, testing for PBP2a (Oxoid). (who.int)
  • Of the 270 clinical isolates of S. aureus, 25.1% (68/270) were MRSA. (biomedcentral.com)
  • Clindamycin in macrolide-lincosamide streptogramin B (MLS B ) family of antibiotics serves as one such alternative for treating both methicillin susceptible S. aureus (MSSA) and methicillin resistant S. aureus (MRSA) infections, due to its excellent pharmacokinetic properties [ 2 ]. (biomedcentral.com)
  • In this study, the occurrence of major antimicrobial resistant bacteria, methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant coagulase negative staphylococci (MR-CNS), vancomycin-resistant enterococci (VRE), and expended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae was investigated among veterinary staff, hospitalized animals, and hospital environments in small animal hospitals in Korea. (vin.com)
  • Prevalence and antimicrobial susceptibility of methicillin-resistant staphylococcus aureus (MRSA) from outpatients with chronic rhinosinusitis in Al-Kut/Wasit Province/Iraq. (who.int)
  • Methicillin resistant S. aureus (MRSA) has become a major public health predicament worldwide. (who.int)
  • Health facilities in the state should institute effective antimicrobial stewardship, intensify surveillance and screening of Staphylococcus aureus for MRSA strains to guard against dissemination of multidrug resistant strains in both hospital and community settings because of the clinical implications. (who.int)
  • Target bacteria included extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL), carbapenem-resistant- P.aeruginosa (CR-PA), carbapenem-resistant- A.baumannii (CR-AB) and methicillin-resistant S.aureus (MRSA). (biomedcentral.com)
  • The baseline prevalence of colonization by ESBL, CR-PA, CR-AB and MRSA at any site was 52.2%, 6.8%, 4.7% and 7.2%, respectively. (biomedcentral.com)
  • The baseline prevalence of colonization by ESBL was relatively high, whereas the baseline prevalence of colonization by CR-PA, CR-AB and MRSA was comparable to previous studies. (biomedcentral.com)
  • Nasal colonization by methicillin-resistant Staphylococcus aureus (MRSA) has been widely investigated. (biomedcentral.com)
  • The objective of a new study published in the journal Zoonoses was to determine the prevalence, antimicrobial resistance, virulence profiles, and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) obtained from ready-to-eat (RTE) foods in China. (phys.org)
  • The objective of the study was to determine the frequency of Methicillin-resistant S. aureus (MRSA) in Peshawar, Pakistan. (springeropen.com)
  • Out of total 280 S. aureus isolates, the frequency of MRSA was 36.1 % (n = 101). (springeropen.com)
  • While MRSA exhibited 100 % susceptibility to vancomycin and linezolid. (springeropen.com)
  • 2010 ). Emergence of antibiotics resistant S. aureus especially Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide problem in both healthcare and community settings (Chambers and DeLeo 2009 ). (springeropen.com)
  • Newborn acquires Staphylococcus aureus including methicillin resistant Staphylococcus aureus (MRSA) from adult sources. (fortunepublish.com)
  • Methi-cillin resistant Staphylococcus aureus (MRSA) has emerged as a virulent pathogen causing significant increase in late-onset infections in premature and critically ill infants in the U.S. neonatal intensive care units (NICUs) [2]. (fortunepublish.com)
  • Newborn acquires Staphylococcus aureus including MRSA from adult sources because many healthy people may carry it as a part of the normal micro flora associated with the nose, throat, perineum or skin [3]. (fortunepublish.com)
  • Antimicrobial resistance in S. aureus has increased dramatically, particularly in the hospital, where the rapid emergence of methicillin-resistant S. aureus (MRSA) and the appearance of S. aureus isolates with resistance to vancomycin have led to concern that this organism may become untreatable with currently available antimicrobials. (cdc.gov)
  • However, no prospective, population-based prevalence study has been done to measure the prevalence of MRSA in the community, and no national surveillance exists to provide a reliable national population estimate. (cdc.gov)
  • Isolates resistant to OX (MRSA), intermediate to OX, and every 10th isolate susceptible to OX (MSSA) by disk diffusion are saved for additional testing of organism characteristics. (cdc.gov)
  • This study aimed to investigate the prevalence of Methicillin-Resistant Staphylococcus aureus (MRSA) and the presence of mecA gene as a virulence factor of S. aureus isolates from clinical isolates and hospital staff nasal carriers using a conventional PCR. (ijpsr.com)
  • The MRSA became resistant to methicillin due to an acquisition of the mecA gene. (ijpsr.com)
  • All isolated S. aureus strains among the hospital staff nasal carriers were MRSA may influence the spread of bacteria and increase the percentage of persistent nosocomial infections in hospitalized patients. (ijpsr.com)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a severe public health concern, responsible for hospital and community-associated infections worldwide 7, 9-11 . (ijpsr.com)
  • The findings from this study will contribute to the current knowledge on the prevalence and diversity of MRSA in Khartoum State. (ijpsr.com)
  • Assessing the prevalence and resistance patterns of methicillin-resistant Staphylococcus aureus (MRSA) in hospital settings. (dissertation-help.uk)
  • The rise of community-acquired methicillin-resistant S. aureus (CA-MRSA) in the late 1990s and early 2000s drove significant increases in use of anti-MRSA antibiotics, such as clindamycin. (pids.org)
  • Fifty-four (68.4%) of the isolates were methicillin resistant S. aureus (MRSA). (biomedcentral.com)
  • The activity of six fluoroquinolones (FQs) was determined against 100 methicillin-resistant Staphylococcus aureus (MRSA) isolated in 2002 along with mutations in the grlA and gyrA genes and in the norA promoter of these isolates. (shengsci.com)
  • Methicillin Resistant Staphylococcus aureus (MRSA) is one of the major causes of nosocomial infections and are most profound in community in previously healthy individuals. (scialert.net)
  • Almost 44 (22%) S. aureus were isolated and characterized with 36 (82%) strains producing β-lactamase and were resistant to oxacillin (MRSA) while, 8 (18%) strains do not produce β-lactamase and were sensitive to oxacillin (MSSA). (scialert.net)
  • This study detected the presence of antibiotic resistant and virulence genes associated with MRSA in MSSA, which calls for urgent clinical and pharmaceutical attention. (scialert.net)
  • Previous studies were critical on Methicillin resistant S. aureus (MRSA) and Methicillin sensitive S. aureus (MSSA) which has posed a serious therapeutic challenge and multidrug resistance among hospitalized individuals with the detection of mec A genes and other virulence genes 3 , 4 . (scialert.net)
  • Out of the 512 MSSA strains, 449 (87.7%) were resistant to penicillin while, 155 (89.6%) of 173 MRSA were resistant to penicillin as reported by Naik and Teclu 2 . (scialert.net)
  • Some of the most important strain types are methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant Staphylococcus aureus (MRSA), community-associated MRSA (CA-MRSA), hospital-associated MRSA (HA-MRSA) and livestock-associated MRSA (LA-MRSA). (stemcelldaily.com)
  • Prevalence of MRSA strains in P. americana and B. germanica cockroaches were 52.77 and 43.33%, respectively. (infectioncontroltoday.com)
  • ex Fotsch were assessed against methicillin-resistant Staphylococcus aureus (MRSA) strain. (org.ua)
  • The ethanolic extracts from nine Begonia plant species were evaluated for their antimicrobial activity against methicillin-resistant S. aureus (MRSA) strain. (org.ua)
  • A total of 100 nasal swabs were collected from healthy food handlers and analyzed for Staphylococcus aureus ,methicillin resistant Staphylococcus aureus (MRSA) and vancomycin resistant Staphylococcus aureus (VRSA) using standard methods. (edu.iq)
  • Activity of plant extracts used in northen Nigerian traditional medicine against methicillin resistant Staphylococuus aureus (MRSA). (edu.iq)
  • Antimicrobial resistance profile of S. aureus isolates from raw meat: a research for MRSA. (edu.iq)
  • Current status of vancomycin susceptibility against methicillin resistant Staphylococcus aureus (MRSA) strains: A study at two tertiary care hospitals of Pakistan. (edu.iq)
  • We isolated methicillin-resistant Staphylococcus aureus (MRSA) from cows with subclinical mastitis and from a person who worked with these animals. (cdc.gov)
  • Although S. aureus is known to be one of the most common causes of bovine mastitis and other severe animal diseases such as septicemia and wound, bone, and joint infections, MRSA strains have been rarely isolated from animals. (cdc.gov)
  • None of the MRSA or methicillin-susceptible S. aureus (MSSA) strains were lysed by phages in RTD. (cdc.gov)
  • Methicillin resistant Staphylococcus aureus (MRSA) is a major public health problem found in nosocomial infections. (biomedcentral.com)
  • To estimate the prevalence of nasal carriage of MRSA in the surgical staff of the Hospital of Lomé Sylvanus Olympio. (biomedcentral.com)
  • No MRSA were resistant to vancomycin. (biomedcentral.com)
  • IntroductionMethicillin resistant Staphylococcus aureus (MRSA) is a major human pathogen associated with nosocomial and community infections. (ox.ac.uk)
  • Methicillin-resistant S. aureus (MRSA) emerged 50 years ago as a nosocomial pathogen but in the last decade it has also become a frequent cause of infections in the community. (frontiersin.org)
  • Resistance to methicillin - that indicates resistance to all beta-lactam agents - was first reported in 1961, the date that marks the appearance of Methicillin-resistant S. aureus (MRSA). (frontiersin.org)
  • Guidelines for the Laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA). (up.ac.pa)
  • Characterization of methicillin resistant Staphylococcus aureus (MRSA) isolated at the Policlinic Hospital of Bari (Italy). (up.ac.pa)
  • Genome sequencing to understand the molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in Tanzania. (cam.ac.uk)
  • The new MRSA was discovered during an epidemiological project looking at the transmission of S. aureus in dairy cows by one of our PhD students, Laura Garcia Alvarez. (cam.ac.uk)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of healthcare-associated infections. (biomedcentral.com)
  • Methicillin-resistant Staphylococcus aureus (MRSA) is involved in increasing number of serious infectious with high risk for morbidity and mortality and it is an important cause of healthcare-associated infections [ 1 ]. (biomedcentral.com)
  • The Aim was to determine the prevalence and resistance of MRSA ,VRSA,VISA isolates from various clinical samples in a tertiary care hospital. (aimdrjournal.com)
  • As there is high prevalence of MRSA isolates so the treatment options are limited to vancomycin. (aimdrjournal.com)
  • The current study aimed to use Coagulase gene polymorphism to identify methicillin-resistant Staphylococcus aureus (MRSA) subtypes isolated from nasal carriers in Minia governorate, Egypt, evaluate the efficiency of these methods in discriminating variable strains, and compare these subtypes with antibiotypes. (hindawi.com)
  • The increasing rate of CA-MRSA infections in many areas, coupled with the organism's unique pattern of virulence, clinical picture, and antimicrobial resistance, has important implications for treatment and infection control measures and acts as a serious challenge for the clinician [ 3 ]. (hindawi.com)
  • Methicillin-resistant S. aureus (MRSA) is one of the modern pathogens which poses a formidable clinical threat. (jmaacms.com)
  • In this review, we provide an overview of clinical research on the treatment of MRSA infections and summarize the expansive body of literature on the clinical trials done to explore new drugs to counteract S. aureus infections. (jmaacms.com)
  • Methicillin-resistant Staphylococcus aureus (MRSA): antibiotic-resistance and the biofilm phenotype. (jmaacms.com)
  • Methicillin resistant staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. (jmaacms.com)
  • Antibiogram of methicillin resistant staphylococcus aureus (MRSA) in healthcare settings. (jmaacms.com)
  • Methicillin-sensitive S. aureus , Streptococcus pneumoniae , and Haemophilus influenzae are most commonly implicated when pneumonia develops within 4 to 7 days of hospitalization, whereas P. aeruginosa , MRSA, and enteric gram-negative organisms become more common with increasing duration of hospitalization. (msdmanuals.com)
  • Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
  • Staphylococcus aureus, an important nosocomial pathogen, is frequently associated with infections in human. (biomedcentral.com)
  • The management of the infections by it especially methicillin resistant ones is often difficult because methicillin resistant S. aureus is usually resistant to multiple antibiotics. (biomedcentral.com)
  • Emerging resistance to methicillin in this organism has left us with very few therapeutic alternatives to treat the infections caused by them. (biomedcentral.com)
  • Tackling drug-resistant infections globally: final report and recommendations. (who.int)
  • 5 infections caused by S. aureus . (who.int)
  • Unfortunately, the suspected cases of ear, wound and urinary tract report of emergence of vancomycin intermediate infections at both tertiary (UUTH) and secondary sensitive S. aureus (VISA) and vancomycin (GHIA) healthcare facilities in Akwa Ibom State. (who.int)
  • Colonization with multidrug-resistant (MDR) bacteria is a major risk factor for developing subsequent MDR infections. (biomedcentral.com)
  • Based on the data from a recent surveillance study performed in a medical ICU in Korea, active surveillance detected carbapenem-resistant- Acinetobacter baumannii (CR-AB) in 15.0% of patients, and approximately one-third of them later developed CR-AB infections [ 14 ]. (biomedcentral.com)
  • Staphylococcus aureus ( S. aureus ) is a serious risk to public health as it causes human infections ranges from wound abscess to life threatening conditions (Deleo et al. (springeropen.com)
  • Findings of the study will be helpful for devising an appropriate hospital antibiotic stewardship policy to reduce the chances of S. aureus associated infections in the area. (springeropen.com)
  • The SENTRY Antimicrobial Surveillance Program in the United States does not list group D streptococci among the 10 most common organisms that cause bloodstream infections, accounting for no more than 1% of all cases. (medscape.com)
  • Staphylococcus aureus , a commensal of human skin and mucosae is the second most common pathogen responsible for health-care associated infections (HAIs) in newborn that accounts for high morbidity, mortality, and healthcare-associated costs [1]. (fortunepublish.com)
  • Vancomycin Resistant Staphylo-coccus Aureus (VRSA) is also an emerging problem in health care associated infections in hospital. (fortunepublish.com)
  • Hospital-acquired pneumonia Ventilator-associated pneumonia Urinary tract infection Gastroenteritis Puerperal fever Central line-associated blood stream infection Staphylococcus aureus Methicillin resistant Staphylococcus aureus Candida albicans Pseudomonas aeruginosa Acinetobacter baumannii' Stenotrophomonas maltophilia Clostridium difficile Escherichia coli Tuberculosis Vancomycin-resistant Enterococcus Legionnaires' disease In-dwelling catheters have recently been identified with hospital acquired infections. (wikipedia.org)
  • To deal with this complication, procedures are used, called intravascular antimicrobial lock therapy, that can reduce infections that are unexposed to blood-borne antibiotics. (wikipedia.org)
  • The use of antibiotics does not, itself, increase risk of hospital-acquired infections, but does contribute to the prevalence of Antimicrobial resistant organisms amongst patients with hospital-acquired infections Given the association between invasive devices and hospital-acquired infections, specific terms are used to delineate such infections to allow for monitoring and prevention. (wikipedia.org)
  • S. aureus is reported as the second driving cause of nosocomial infections, especially in patients undergoing surgery, hemodialysis, cirrhosis, kidney transplant, and hospitalized patients 6-8 . (ijpsr.com)
  • Investigating the potential of phage therapy for the treatment of antibiotic-resistant respiratory tract infections. (dissertation-help.uk)
  • Assessing the prevalence and antibiotic resistance patterns of Neisseria gonorrhoeae in sexually transmitted infections. (dissertation-help.uk)
  • Investigating the role of the vaginal microbiome in susceptibility to sexually transmitted infections. (dissertation-help.uk)
  • Since the 1980s, antibiotic-resistant infections have become increasingly common. (pids.org)
  • Recent estimates of the burden of antimicrobial resistance suggest that there are approximately 700,000 deaths worldwide every year due to infections with antimicrobial resistant bacteria, with nearly 50,000 of these deaths occurring in the United States and Europe (CDC. (pids.org)
  • Drug resistant S. pneumoniae is considered a serious by the CDC, with an estimated 2 million infections each year. (pids.org)
  • In more than 30% of infections, the isolate will be resistant to one or more clinically useful antibiotics (CDC, Antibiotic Resistance Threat Report , 2019. (pids.org)
  • Development of resistance to commonly used antimicrobials limited treatment options against infections due to this pathogen. (biomedcentral.com)
  • S. aureus isolates from patients in TASH exhibited resistance to majority of antimicrobials commonly employed for the treatment of staphylococcal infections which calls for urgent need of prudent use of antimicrobials and the need for implementation of effective infection control practices to hamper spread of MDR S. aureus . (biomedcentral.com)
  • S. aureus is reported to be the most common cause of nosocomial infections and is particularly responsible for majority of surgical site infections [ 5 ]. (biomedcentral.com)
  • Such findings may eventually change our attitude toward individual antibiotic risk to a greater degree than the threat of resistant infections alone. (blogspot.com)
  • It is estimated that Staphylococcus aureus causes more than 11 million infections and 20,000 deaths annually in the United States alone. (stemcelldaily.com)
  • The emergence and spread of antibiotic-resistant strains pose a serious challenge for the treatment and prevention of staphylococcal infections. (stemcelldaily.com)
  • Diabetes Awareness Month in November highlights the heightened susceptibility of diabetes patients to infections. (infectioncontroltoday.com)
  • Our studies indicated that Begonia plants are worthy of further investigation as a potential phytotherapeutic agent for treating infections caused by S. aureus. (org.ua)
  • Screening for antimicrobial activity of nine ethanolic extracts obtained from leaves of Begonia plant: a possible alternative in the treatment of infections caused by Citrobacter freundii . (org.ua)
  • When S. aureus gains entry into the host, it is able to cause a variety of infections, from mild skin infection to life threatening invasive infections. (frontiersin.org)
  • Methicillin-resistant Staphylococcus aureus in community-acquired skin infections. (medscape.com)
  • Daskalaki M, Rojo P, Marin-Ferrer M, Barrios M, Otero JR, Chaves F. Panton-Valentine leukocidin-positive Staphylococcus aureus skin and soft tissue infections among children in an emergency department in Madrid, Spain. (medscape.com)
  • Repeats in the 3' region of the protein A gene is unique in a strain of Staphylococcus aureus recovered from wound infections in Lagos. (up.ac.pa)
  • The proposed surveillance system is intended to monitor only invasive pneumococcal infections and their antimicrobial susceptibility patterns. (cdc.gov)
  • A confirmed case of invasive DRSP is defined as either meningitis or bacteremia in which S. pneumoniae cultured from CSF or blood is identified as nonsusceptible (using National Committee for Clinical Laboratory Standards {NCCLS} methods and breakpoints) to antimicrobial drugs currently approved for treating pneumococcal infections. (cdc.gov)
  • The study aimed to identify the outcomes and attributable cost of treatment in patients with resistant bacterial infections. (japsonline.com)
  • Management of multidrug-resistant (MDR) infections is associated with a higher cost requiring second-line agents, additional investigations, and increased length of stay (LoS). (japsonline.com)
  • Health Protection Research Unit (Healthcare-associated Infections and Antimicrobial Resistance) Research into livestock-associated AMR (Cambridge project) funded by National Institute for Health Research (RG79375). (cam.ac.uk)
  • Bacterial genome sequencing to understand S. aureus infections in rabbits. (cam.ac.uk)
  • Obesity is a risk factor for both susceptibility to infections including postoperative infections and other nosocomial infections and the occurrence of a more severe disease course. (hrb.ie)
  • Methicillin Resistant Staphylococcus aureus are implicated in serious infections and nosocomial infection outbreaks, thus limiting the treating options to very few agents such as vancomycin and teicoplanin. (aimdrjournal.com)
  • Infection control can prevent additional infections and the spread of resistant pathogens and thereby reduce the need to use antibiotics. (asm.org)
  • All strains of S. aureus produce coagulase enzyme, and its production can identify S. aureus infections [ 9 ]. (hindawi.com)
  • Juneja S, Kalia R, Singh RP, Roy V. Staphylococcus Infections and Emerging Drug Resistance: A Global Concern. (jmaacms.com)
  • Staphylococcus aureus ( S. aureus ) infections are a global health concern resulting in morbidity and mortality worldwide. (jmaacms.com)
  • Numerous antimicrobial agents (AMAs) have been developed over the years to treat S. aureus infections and then followed by the rapid emergence of resistance to them. (jmaacms.com)
  • The clinical impact can be achieved with some promising newer antibiotics which can deal with different types of infections caused by S. aureus . (jmaacms.com)
  • Antimicrobial resistance and molecular epidemiology of staphylococcus aureus causing bloodstream infections at Ruijin Hospital in Shanghai from 2013 to 2018. (jmaacms.com)
  • This increase poses several problems, including a) the lack of available antimicrobials for therapy of infections caused by VRE, because most VRE are also resistant to multiple other drugs (e.g., aminoglycosides and ampicillin) previously used for the treatment of infections due to these organisms, and b) the possibility that the vancomycin resistance genes present in VRE may be transferred to other gram-positive microorganisms such as Staphylococcus aureus. (cdc.gov)
  • INTRODUCTION From 1989 though 1993, the percentage of nosocomial enterococcal infections reported to the Centers for Disease Control and Prevention (CDC) National Nosocomial Infections Surveillance (NNIS) System that were caused by vancomycin-resistant enterococci (VRE) increased from 0.3% to 7.9%[1]. (cdc.gov)
  • Staphylococcus aureus , one of the most common nosocomial and community-acquired pathogens has now emerged as an ever-increasing problem due to its increasing resistance to several antibiotics. (biomedcentral.com)
  • As a public health tool, AST data that describe the prevalence, geographic distribution and temporal trends of resistant pathogens should inform standard treatment guidelines that are developed in the Pacific region. (who.int)
  • Empirical antibiotic therapy should be based on knowledge of likely pathogens for the site of infection, information from patient history (e.g., recent hospitalizations, work-related exposure, travel, and pets), and local susceptibility. (basicmedicalkey.com)
  • Staphylococcus aureus is one of the major pathogens of public health importance responsible for various forms of infection. (biomedcentral.com)
  • The ability of S. aureus to invade the host immune system through various virulence factors and its rapid acquisition of multi-drug resistance phenotype, makes it one of the most notorious organism among gram positive bacterial pathogens [ 3 ]. (biomedcentral.com)
  • The burden of infection with antimicrobial resistant strains of pathogens involves increased risk of mortality, increased hospital stay, and related attributable costs compared to infection with antimicrobial susceptible pathogens [ 4 ]. (biomedcentral.com)
  • These practices can facilitate the emergence of new pathogens, including antibiotic-resistant organisms, and their transmission to humans. (frontiersin.org)
  • The total cost burden of antimicrobial resistance (AMR) due to MDR pathogens was reported as $0.5 billion and $2.8 billion in LMICs and high-income countries, respectively. (japsonline.com)
  • Optimal use of microbiology laboratories is essential to combat the spread of multiply antibiotic-resistant pathogens. (asm.org)
  • This is vital for patient care, as advocated by Jarvis in stressing the importance of active detection and isolation to control methicillin-resistant Staphylococcus aureus and other resistant hospital-acquired pathogens ( 17 ). (asm.org)
  • The absence of new, effective anti-gram-negative antibiotics makes infection control the most important countermeasure against multidrug-resistant gram-negative pathogens. (asm.org)
  • Some resistant pathogens may not be recognized because they are falsely susceptible in routine tests. (asm.org)
  • Antimicrobial Agents Chemotherapy, 52(9): 3188-94. (cdc.gov)
  • Journal of antimicrobial chemotherapy, 56 (6), 1000-1018. (up.ac.pa)
  • Clinical Microbiology and Antimicrobial Chemotherapy. (cmac-journal.ru)
  • Inappropriate antibiotic use is a huge problem in Ethiopia, and many bacteria were resistant to commonly used antibiotics and similarly, multidrug-resistant bacterial strains are numerous. (hindawi.com)
  • Emerging bacterial antimicrobial (antibiotic) resistance (AMR) is a global threat to human health. (who.int)
  • Knowledge of bacterial antimicrobial susceptibility testing (AST) patterns is the cornerstone of an effective clinical and public health response to AMR. (who.int)
  • Italy, a company specializing in the development, production, and distribution of automated clinical diagnostic instruments, practices sensitive laser-light scattering technology to detect bacterial growth in a liquid culture broth and provides antimicrobial susceptibility results directly from positive blood culture bottles within 4-6 hours. (precisionbusinessinsights.com)
  • Furthermore, in 2018, Beckman Coulter Inc., a subsidiary of Danaher, announced the commercialization of its DxM MicroScan WalkAway system, a diagnostic solution for bacterial detection and antibiotic susceptibility testing for microbiology research laboratories. (precisionbusinessinsights.com)
  • bacterial etiology, pregnant women, susceptibility profile. (ispub.com)
  • The nationwide Active Bacterial Core pneumococcal surveillance report from 2018 found that 4.7% of invasive pneumococcal isolates were resistant or intermediate to penicillin and 2.6% were resistant or intermediate to cefotaxime. (pids.org)
  • In a previous study in northern Ethiopia, the rate of surgical site infection accounted for 10.2% and S. aureus was shown to be the leading bacterial pathogen responsible for surgical site infection [ 6 ]. (biomedcentral.com)
  • Methicillin resistance is due to the acquisition of the mecA gene, that encodes a new protein designated PBP2a, belonging to a family of enzymes necessary in building the bacterial cell wall. (frontiersin.org)
  • Background We have previously reported, in a systematic review of 181 studies, that restriction of antibiotic use in food-producing animals is associated with a reduction in antibiotic-resistant bacterial isolates. (bmj.com)
  • Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals approved standard. (ac.ir)
  • Clinicians in Pacific island nations are increasingly challenged by patients who have infection due to antimicrobial-resistant bacteria. (who.int)
  • Phytochemical compounds were analyzed in vitro in ethanolic extracts of Passiflora incarnata L. , P. edulis Sims, P. caerulea L. leaves and fruits to determine the antimicrobial activity against six pathogenic bacteria. (cyberleninka.ru)
  • Staphylococcus aureus is a bacteria that causes a heavy epidemic disease burden worldwide. (ijpsr.com)
  • Some of the most worrisome antibiotic-resistant bacteria are MDR Enterobacterales , which includes species like E. coli and Klebsiella pneumoniae . (pids.org)
  • Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment [Article]. (sva.se)
  • Staphylococcus aureus is a type of bacteria that belongs to the genus Staphylococcus, which consists of spherical-shaped, Gram-positive organisms that usually form clusters resembling grapes. (stemcelldaily.com)
  • The aim of this study was to determine the prevalence of the nasal carriage of vancomycin resistant Staphylococcus aureus among food handlers in restaurants and cafeterias, and to evaluate of antibacterial activity of cinnamon and ginger extracts against these bacteria. (edu.iq)
  • Drug-resistant bacteria can circulate in populations of human beings and animals, through food, water and the environment, and transmission is influenced by trade, travel and both human and animal migration. (who.int)
  • Resistant bacteria can be found in food animals and food products destined for consumption by humans. (who.int)
  • This approach is controversial ( 19 ) but has been adopted in slightly different forms by the European Committee on Antimicrobial Susceptibility Testing and the CLSI. (asm.org)
  • Nasal swab was collected aseptically using sterile cotton swab by the trained research assistant from both the nostrils following standard procedure and was sent immediately to microbiology lab for isolation and identification of Staphylococcus strain following standard procedure and drug susceptibility testing. (fortunepublish.com)
  • they were then plated on mannitol salt agar (MSA), a selective media for the isolation of S. aureus . (cdc.gov)
  • Wound and corresponding nasal swabs from patients with surgical site infection from general surgery ward ( n = 14), orthopedic ward ( n = 21) and those with otitis media ( n = 59) from Ear Nose and Throat (ENT) ward were cultured for S. aureus isolation according to standard procedures from December 2013 to June 2014. (biomedcentral.com)
  • About 200 clinical samples were obtained for S. aureus isolation, identified and characterized by using standard microbiological procedures. (scialert.net)
  • Two hundred clinical wound and burn samples were obtained with sterile cotton swabs from tertiary health care facilities within Delta state, Nigeria, for S. aureus isolation. (scialert.net)
  • Isolation of Staphylococci from food handlers and investigation of their enterotoxigenicity and susceptibility to some antibiotics. (edu.iq)
  • 11. Sasaki Y, Asai T, Haruna M, Sekizuka T, Kuroda M, Yamada Y. Isolation of methicillin-resistant Staphylococcus aureus ST398 from pigs in Japan. (gifu-u.ac.jp)
  • 14. Sasaki Y, Yamanaka M, Nara K, Tanaka S, Uema M, Asai T, Tamura Y. Isolation of ST398 methicillin-resistant Staphylococcus aureus from pigs at abattoirs in Tohoku region, Japan. (gifu-u.ac.jp)
  • 6. Ichikawa T, Oshima M, Yamagishi J, Muramatsu C, Asai T. Changes in antimicrobial resistance phenotypes and genotypes in Streptococcus suis strains isolated from pigs in the Tokai area of Japan. (gifu-u.ac.jp)
  • Molecular characterization of Staphylococcus intermedius carriage by healthy dogs and comparison of antimicrobial susceptibility patterns to isolates from dogs with pyoderma. (ac.ir)
  • Genetic and phenotypic characterization of methicillin-resistant staphylococci isolated from veterinary hospitals in South Korea. (ac.ir)
  • All observational studies reporting on the prevalence, antimicrobial resistance/susceptibility, or characterization of Listeria species in Africa were searched on PubMed, Web of Science, EMBASE, Google Scholar and the Cochrane Library for this review. (biomedcentral.com)
  • Wei Wang et al, Antimicrobial Resistance, Virulence, and Genetic Characterization of Methicillin-Resistant Staphylococcus aureus Recovered from Ready-to-Eat (RTE) Food in China: A New Challenge for Food Safety, Zoonoses (2023). (phys.org)
  • Characterization of methicillin-resistant staphylococcus aureus isolated from nearby hospitals from two different countries. (jmaacms.com)
  • The pooled prevalence of multidrug resistant strains identified was 59.7% (95% CI: 43.5-75.9). (hindawi.com)
  • Comparative Sequence Analysis of Multidrug-Resistant IncA/C Plasmids from Salmonella enterica. (cdc.gov)
  • The market for antimicrobial susceptibility is growing due to the high incidence of infectious diseases, increasing government programs and investment in antimicrobial susceptibility testing programs, technological advancements for developing new AST methods, and the rise of multidrug resistance in microorganisms. (precisionbusinessinsights.com)
  • Analyzing the emergence and spread of multidrug-resistant tuberculosis in the UK. (dissertation-help.uk)
  • Imipenem heteroresistance induced by imipenem in multidrug-resistant Acinetobacter baumannii: mechanism and clinical implications. (shengsci.com)
  • Here we report the clinical impact and mechanism of imipenem heteroresistance (imipenem minimum inhibitory concentration of 6-32 μg/mL with the presence of resistant cells inside the inhibition zone of Etest strips or disks) in multidrug-resistant A. baumannii (MDR-AB). (shengsci.com)
  • increased from 17.7 to 33.0 % and multidrug-resistant Acinetobacter spp. (blogspot.com)
  • Dhanalakshmi TA, Umapathy BL, Mohan DR. Prevalence of methicillin, vancomycin and multidrug resistance among Staphylococcus aureus. (edu.iq)
  • A high prevalence of management of multidrug-resistant (MDR) and extensive/pan-drug-resistant Gram-negative and MDR Gram-positive isolates was identified. (japsonline.com)
  • Most of them were isolated from pus followed by blood and urine specimen and most were found to be multidrug resistant while they retained their sensitivity to Linezolid and Teicoplanin. (aimdrjournal.com)
  • This information, combined with knowledge of the most likely offending organism(s) and an institution's local susceptibility patterns, should result in a rational selection of antibiotics to treat the patient. (basicmedicalkey.com)
  • Assessing antimicrobial prescribing practices and resistance patterns in UK hospitals. (dissertation-help.uk)
  • Speciation and antifungal susceptibility patterns of Candida isolates from urine specimens. (jacmjournal.org)
  • Projects based in Iowa examine the patterns of drug resistant Staphylococcus aureus , particularly in relationship to livestock production. (uiowa.edu)
  • Spatio-temporal Patterns of Drug-Resistant Malaria in the Democratic Republic of Congo. (uiowa.edu)
  • This study was conducted over the period of one and half year from November 2013-April 2015 in Microbiology laboratory of Nepal Medical College and Teaching Hospital, Kathmandu, Nepal to find the incidence of different phenotypes of MLS B resistance among S. aureus from clinical samples and their association with methicillin resistance. (biomedcentral.com)
  • 9. Agha Khan University Hospital Clinical Laboratory Microbiology antibiotic susceptibility report Jan-Dec 2016. (who.int)
  • The susceptibility of S. aureus was performed according to the recommendations of the French Society for Microbiology. (biomedcentral.com)
  • The main objective of this study was to explore the prevalence, antibiotic susceptibility pattern, and mec A gene.MethodsA total of 39 isolates of S. aureus were isolated from 954 clinical specimens processed in Microbiology laboratory of Himal Hospital, Kathmandu. (ox.ac.uk)
  • Currently, national surveillance programs only focus on food animals, and data on companion animals, which are in close contact with humans, are needed for assessing the risk of transmission of antimicrobial resistance. (vin.com)
  • 8. Antimicrobial resistance: global report on surveillance 2014. (who.int)
  • A surveillance study reported that the prevalence of rectal colonization by ESBL-producing Enterobacteriaceae among newly-hospitalized general medical patients in an Israel teaching hospital was only 8% [ 9 ]. (biomedcentral.com)
  • Regular antibiotic susceptibility surveillance in addition to antibiotic stewardship policy should be adopted. (ispub.com)
  • The potential of using E. coli as an indicator for the surveillance of antimicrobial resistance (AMR) in the environment [Review]. (sva.se)
  • The Tigecycline Evaluation and Surveillance Trial (T.E.S.T) is a global antimicrobial surveillance study of both gram-positive and gram-negative organisms. (blogspot.com)
  • Analysis of typing methods for epidemiological surveillance of both methicillin-resistant and methicillin susceptible Staphylococcus aureus strains. (up.ac.pa)
  • Blood Culture samples were also obtained at an intensive care unit (ICU) of the same hospital, as part of an antimicrobial resistance surveillance project (unpublished data). (biomedcentral.com)
  • We evaluated the One Health-ness (OH-ness) of the surveillance system for antimicrobial resistance (AMR) in Norway by using the recently developed "Evaluation tool for One Health epidemiological surveillance capacities and capabilities" (OH-EpiCap tool). (mdpi.com)
  • However, strains of S. aureus have been described that are vancomycin-susceptible by conventional testing but have a subpopulation of resistant cells. (cdc.gov)
  • 1,2 Patients with sepsis who are treated with an antimicrobial for which the causative pathogen is non-susceptible have an increased risk of mortality. (who.int)
  • While Streptococcus pyogenes remains highly susceptible to beta-lactam antibiotics, over the past decade increasing prevalence of clindamycin and macrolide resistance are being reported worldwide. (pids.org)
  • To identify risk factors associated with the emergence of imipenem heteroresistance, a retrospective case-control study was undertaken involving cases with subsequent clinical isolates of the same genotype showing loss of imipenem susceptibility and matched controls with isolates belonging to imipenem-susceptible MDR-AB. (shengsci.com)
  • Their effect was more pronounced in methicillin resistant than in susceptible strains. (shengsci.com)
  • All gram-positive organisms were susceptible to tigecycline and susceptibility among gram-negatives ranged from 95.0 % for K. pneumoniae to 99.7 % for E. coli. (blogspot.com)
  • Choosing an antimicrobial agent to treat an infection is far more complicated than matching a drug to a known or suspected pathogen. (basicmedicalkey.com)
  • Therefore, it is essential to understand the bacteriology, clinical diseases and diagnosis of Staphylococcus aureus in order to develop effective strategies to combat this formidable pathogen. (stemcelldaily.com)
  • Staphylococcus aureus is a typical human pathogen. (frontiersin.org)
  • Antimicrobial resistance occurs through different mechanisms, which include spontaneous (natural) genetic mutations and horizontal transfer of resistant genes through deoxyribonucleic acid (DNA). (who.int)
  • In case of another mechanism of resistance mediated through msr A genes i.e. efflux of antibiotic, staphylococcal isolates appear erythromycin-resistant and clindamycin-sensitive both in vivo and in vitro and the strain do not typically become clindamycin resistant during therapy [ 5 ]. (biomedcentral.com)
  • Susceptibility and resistance genes to fluoroquinolones in methicillin-resistant Staphylococcus aureus isolated in 2002. (shengsci.com)
  • The quantification of PCR products indicated that sea genes (virulence enterotoxin factor) were detected from the antibiotic resistant staphylococci ranging from 0-13551.84 nmoles while, the quantification of mec A genes detected ranged from 0-2601.76 nmoles. (scialert.net)
  • The agarose gel electrophoresis of the PCR products of mec A and sea genes showed amplicon size of 657 bp for mec A and 526 bp for sea genes after amplification of the antibiotic resistant S. aureus strains. (scialert.net)
  • However, owing to paucity of information on the methicillin sensitive strains and the detection of both resistant and virulent genes from other studies have not been linked with wound and burn samples, thus the need for this study. (scialert.net)
  • Enterotoxin-encoding genes in Staphylococcus spp. (edu.iq)
  • Los aislados se agruparon en 5 categorías con base en los genes para los cuales se obtuvo amplificación. (up.ac.pa)
  • La categoría 1 con amplificación en los tres genes (24 aislamientos) generó 19 patrones de bandas diferentes. (up.ac.pa)
  • La categoría 2 con amplificación en los genes ( coa y spa ) agrupó 25 aislamientos con 17 patrones diferentes. (up.ac.pa)
  • Determination of the dynamics of antimicrobial resistance genes in the human and animal gut microbiome (with Prof Duncan Maskell, Prof Sharon Peacock, Prof Mark Stevens, Prof James Wood, Dr Olivier Restif, Dr Dan Tucker & Dr Andrew Grant) funded by MRC (MR/N002660/1) October 2015 to September 2018 £1,985,599. (cam.ac.uk)
  • PCR reactions were based on a personal emergence of methicillin resistance in Samples were collected from 569 communication with N. Williams from different strains with varying degrees HCWs (215 doctors and 354 nurses) the University of Liverpool. (who.int)
  • Because of the emergence of PNSP, in December 1994, the New York City Department of Health (NYCDOH) amended the New York City health code to require reporting of PNSP to monitor the local prevalence of resistance to penicillin. (cdc.gov)
  • In addition to the existing problem with VRE, the potential emergence of vancomycin resistance in clinical isolates of Staphylococcus aureus or Staphylococcus epidermidis is a serious public health concern. (cdc.gov)
  • This review is conducted to evaluate the prevalence of inappropriate antibiotic utilization and resistance to antibiotics in Ethiopia. (hindawi.com)
  • Appropriate antibiotic use should be ensured by prohibiting over-the-counter sale of antibiotics and strengthening antimicrobial stewardship. (hindawi.com)
  • Staphylococcus aureus is an increasing problem in clinical practice because of reduced susceptibility to available antibiotics. (springeropen.com)
  • The mec A gene codes for a78-kD a penicillin-binding protein (PBP2a), with decreased affinity to methicillin as well as all beta-lactam antibiotics 15-17 . (ijpsr.com)
  • The β-lactamase and non-β-lactamase isolates were resistant to other antibiotics. (scialert.net)
  • Staphylococcus is notorious for its ability to become resistant to antibiotics. (aimdrjournal.com)
  • The objective of the study was to determine the frequency of Staphylococcus aureus nasal colonization among HCWs and mothers/caregivers attending neonatal intensive care unit (NICU) of Bangabandhu Sheikh Mujib Medical University (BSMMU), to evaluate antibiotic sensitivity pattern of identified organism and to study the risk factors of carriage among the study groups. (fortunepublish.com)
  • Methicillin resistant Staphylococcus aureus nasal colonization among secondary school students at Duhok city-Iraq. (edu.iq)
  • The rapid and ongoing spread of antimicrobial-resistant organisms threatens our ability to successfully treat a growing number of infectious diseases. (hindawi.com)
  • This report presents data on antimicrobial susceptibility among organisms collected in Mexico between 2005 and 2012 as part of T.E.S.T., and compares rates between 2005-2007 and 2008-2012. (blogspot.com)
  • Tigecycline was active against gram-positive and gram-negative organisms, including resistant phenotypes, collected during the study. (blogspot.com)
  • antibiotic-resistant organisms are an important concern. (msdmanuals.com)
  • Antimicrobial Susceptibility Testing Market is expected to be valued at USD 3,645.3 million in 2022, growing at a 6.2% CAGR from 2022 to 2028. (precisionbusinessinsights.com)
  • To determine the prevalence of UTIs, aetiological agents and antimicrobial susceptibility profile of the isolates among pregnant women attending antenatal clinics in some selected hospitals in Enugu. (ispub.com)
  • Therefore, this assay is considered a simple and accurate subtyping method of S. aureus [ 11 ] and can be included in epidemiological studies and routine infection control programs [ 8 ]. (hindawi.com)
  • penicillin and methicillin resistance was first recognized in 1944 and 1961 A.D. respectively [ 1 ]. (biomedcentral.com)
  • isolated from different parts of Africa are generally sensitive to ciprofloxacin, but resistant to penicillin. (biomedcentral.com)
  • since then, in the United States, there has been increased identification of penicillin-nonsusceptible S. pneumoniae (PNSP) (defined as minimum inhibitory concentration {MIC} to penicillin greater than or equal to 0.1 ug/mL), especially penicillin-resistant S. pneumoniae (PRSP) (defined as MIC to penicillin greater than or equal to 2.0 ug/mL). (cdc.gov)
  • resistant S. aureus (VRSA) in clinical samples The study was approved by the Health Ethics impacted negatively on the efficacy of vancomycin Committee of the State Ministry of Health and the 6 leading to treatment failures. (who.int)
  • This study revealed a relatively high prevalence rate of VRSA nasal carriage among food handlers. (edu.iq)
  • Staphylococcus aureus is a major public health concern worldwide due to its high prevalence, morbidity and mortality rates. (stemcelldaily.com)
  • The first S. aureus with reduced vancomycin susceptibility (vancomycin MIC ≥8 μg/mL) was isolated in 1997 ( 3 , 4 ), and similar isolates have since been discovered in several countries. (cdc.gov)
  • This study was conducted to investigate the prevalence of methicillin resistance Staphylococcus aureus among patients in two health facilities in Akwa Ibom State, Nigeria. (who.int)
  • This study was conducted to investigate the prevalence of methicillin resistance Staphylococcus aureusamong patients in two health facilities in Akwa Ibom State, Nigeria.Materials and Methods:Clinical isolates of patients from University of Uyo Teaching Hospital (UUTH), Uyo and General Hospital, Ikot Abasi (GHIA) were investigated based on the strategic location of the hospitals. (bvsalud.org)
  • 73 (26.4%) isolates were multi-drug resistant (MDR). (phys.org)
  • 24/39) were multiple drug resistant (MDR). (ox.ac.uk)
  • ESBL producers are usually multiply drug resistant ( 5 , 30 ), but their cephalosporin and aztreonam resistance is not reliably detected by susceptibility tests ( 33 ). (asm.org)
  • Antimicrobial disk susceptibility tests were performed according to CLSI guideline. (vin.com)
  • Minimum inhibitory concentrations (MICs) were determined using Clinical Laboratory Standards Institute (CLSI) broth microdilution methodology and antimicrobial susceptibility was established using the 2013 CLSI-approved breakpoints. (blogspot.com)
  • Detection of Staphylococcus aureusand MRSAstrains were done according to standard protocols while antibiotic susceptibility testing of MRSAisolates was conducted using Kirby-Bauer disc diffusion method and interpreted following the CLSI 2021 guidelines. (bvsalud.org)
  • For the susceptibility profile determination oxacillin agar screening was used with automated system according with Clinical Laboratory Standards Institute (CLSI) recommendations [ 7 ]. (biomedcentral.com)
  • It causes high mortality and morbidity especially in low- and middle-income countries where access to diagnostics is limited and antimicrobial prescription and intake remain inadequately regulated. (who.int)
  • Infectious diseases generally are acute, and a delay in antimicrobial therapy can result in serious morbidity or even mortality. (basicmedicalkey.com)
  • Les résultats prouvent que les agents de santé libyens peuvent servir de porteurs de Staphylococcus aureus résistant à la méticilline et jouer un rôle dans sa diffusion à la population et aux autres agents. (who.int)
  • Methicillin resistance was detected by cefoxitin disc diffusion method and inducible clindamycin resistance by erythromycin and clindamycin disc approximation test (D-test). (biomedcentral.com)
  • S. aureus isolates are screened for methicillin resistance following the National Clinical and Laboratory Standards Institute (NCCLS) disk diffusion method. (cdc.gov)
  • Antimicrobial susceptibility profile was determined using disc diffusion techniques. (ispub.com)
  • Isolates were investigated for susceptibility to panel of 17 antimicrobials using Kirby Bauer disc diffusion assay. (biomedcentral.com)
  • The testing of the antibacterial activity of the plant extracts was carried out in vitro by the Kirby-Bauer disc diffusion susceptibility test protocol. (org.ua)
  • One of these isolates was resistant to methicillin by disk diffusion and E-test, and the presence of the mec A gene was confirmed by PCR. (cdc.gov)
  • Staphylococcus aureus has remarkable abilities to adapt to different environments and hosts, as well as to resist various antimicrobial agents. (stemcelldaily.com)
  • Staphylococcus aureus bacteremia: epidemiology, pathophysiology, and management strategies. (jmaacms.com)
  • https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-report-508.pdf) A 2014 UK government report projected that the number of annual deaths attributable to antimicrobial resistance would surpass 10 million by the year 2050 if no meaningful interventions occur, possibly surpassing cancer as the number-one cause of mortality worldwide. (pids.org)
  • Predictors of mortality in Staphylococcus aureus bacteremia. (jmaacms.com)
  • The direct consequences of infection with resistant microorganisms can be severe, including longer illnesses, increased mortality, prolonged stays in hospital, loss of protection for patients undergoing operations and other medical procedures, and increased costs. (who.int)
  • Alongside reducing vectors for transmission, patient susceptibility to hospital-acquired infection needs to be considered. (wikipedia.org)
  • A cross-sectional study involving eighty-one S. aureus isolates, 60 clinical isolates, and 21 nasal swabs from hospital staff was conducted from January 2018 to April 2018. (ijpsr.com)
  • All samples from hospital staff were resistant for Methicillin and positive for mecA presence. (ijpsr.com)
  • Sixty S. aureus clinical isolates were collected from Al Ribat Hospital, Bahri Hospital, Soba Hospital in Khartoum State. (ijpsr.com)
  • 40,000 S. aureus isolates identified from inpatient and outpatient settings in a large children's hospital demonstrated resistance to clindamycin and TMP-SMX increased among outpatient isolates between 2005-2014. (pids.org)
  • Antimicrobial resistance profile of Staphylococcus aureus isolated from patients with surgical site infection and ear infection and corresponding nasal swab was investigated in Tikur Anbessa Specialized Hospital (TASH), Addis Ababa, Ethiopia. (biomedcentral.com)
  • Characteristics of Staphylococcus aureus Isolated From Clinical Specimens in a Tertiary Care Hospital, Kathmandu, Nepal. (ox.ac.uk)
  • Distribution of spa types among methicillin-resistant Staphylococcus aureus isolates during a 6-year period at a low -prevalence university hospital. (up.ac.pa)
  • based on species and resistance level, re- antimicrobial agents [2]. (who.int)
  • Species distribution and properties of staphylococci from canine dermatitis. (ac.ir)
  • These species are globally distributed with varying prevalence rates in the different regions. (biomedcentral.com)
  • Yeast-like isolates from urine culture were identified using a Mini-API® (bioMérieux, Marcy-l'Etoile, France) tool with ID 32 C strips (bioMérieux, Marcy-l'Etoile, France) for species identification and ATB Fungus 3 strips (bioMérieux, Marcy-l'Etoile, France) for susceptibility testing to five antifungal agents and results interpreted as per Centers for Disease Control and Prevention (CDC) guidelines. (jacmjournal.org)
  • The most effective plants among species screened against S. aureus NCTC 12493 growth were B. peltata, B. thiemei, B. foliosa, Begonia × erythrophylla, and B. solimutata being highly active with the ethanolic extracts (diameters of inhibition zone ranged from 12.5 to 21 mm). (org.ua)
  • It occasionally lives on domestic animals, although these are usually colonized by other species of staphylococci. (frontiersin.org)
  • Staphylococcus species were confirmed by an automated (Vitek 2 System,, Hazelwood, MO)) and manual biochemical tests. (biomedcentral.com)
  • In this US-wide study, oxacillin susceptibility rose while clindamycin susceptibility fell over time. (pids.org)
  • Susceptibility to methicillin was phenotypically determined based on sensitivity of isolates to cefoxitin and oxacillin. (biomedcentral.com)
  • Methicillin resistance was determined by using β-lactamase assay and oxacillin disk (Oxoid) susceptibility test. (scialert.net)
  • The resistance to methicillin was highlighted by the use of cefoxitin disks and oxacillin. (biomedcentral.com)
  • When oxacillin disk screening is the only antimicrobial susceptibility method used, the antimicrobial susceptibility profile cannot be definitely determined. (cdc.gov)
  • A probable case of invasive DRSP is defined as either meningitis or bacteremia in which S. pneumoniae cultured from CSF or blood is identified as nonsusceptible by oxacillin screening (i.e., zone size less than or equal to 19 mm) and no further antimicrobial susceptibility testing has been performed. (cdc.gov)
  • the first high-level vancomycin-resistant isolates that have acquired the vanA gene cassette from enterococci are also members of this clone (F. Tenover, pers. (cdc.gov)
  • Identification and prevalence of an enterotoxin-related gene, se-int, in Staphylococcus intermedius isolates from dogs and pigeons. (ac.ir)
  • Resistance to methicillin is mediated by mec - A gene, which encodes the polypeptide PBP2a protein (Oliveira et al. (springeropen.com)
  • Methicillin resistance is encoded by the mecA gene, borne on the staphylococcal cassette chromosome mec (SCC mec ). (ijpsr.com)
  • This study aimed to screen the methicillin resistance gene ( mecA ) in S. aureus isolates from patients as well as health care workers. (ijpsr.com)
  • mecA gene is considered one of the important virulence factors of S. aureus responsible for acquiring resistance against methicillin. (ox.ac.uk)
  • The prevalence of methicillin resistance was 46% (18/39) of which 72.2% (13/18) were positive for mecA gene in PCR assay.ConclusionOne in 4 culture positive isolates from the clinical specimens were S. aureus, of which almost two-thirds were MDR. (ox.ac.uk)
  • This study concludes that the mecA gene is solely dependent for methicillin resistance in S. aureus but the presence of gene is not obligatory. (ox.ac.uk)
  • Distribution of the exfoliative toxin D gene in clinical Staphylococcus aureus isolates in France. (medscape.com)
  • 1994). Discrimination of epidemic and nonepidemic methicillin-resistant Staphylococcus aureus strains on the basis of protein A gene polymorphism. (up.ac.pa)
  • The vanA gene, which is frequently plasmid-borne and confers high-level resistance to vancomycin, can be transferred in vitro from enterococci to a variety of gram-positive microorganisms,[18,19] including S. aureus[20]. (cdc.gov)
  • It is very difficult to detect the inducible clindamycin resistance in the routine laboratory as they appear erythromycin-resistant and clindamycin sensitive in vitro when not placed adjacent to each other. (biomedcentral.com)
  • Two hundred seventy-six RTE food-associated S. aureus isolates were collected from 25 provinces across China in 2018, then characterized by antimicrobial susceptibility testing, virulence factors detecting, multi-locus sequence typing (MLST), spa typing, SCCmec typing and pulsed-field gel electrophoresis (PFGE). (phys.org)
  • Staphylococcus aureus can be classified into different strains based on their genetic characteristics, phenotypic properties and epidemiological features. (stemcelldaily.com)
  • The results of in vitro susceptibility testing of ESBL producers indicate that the activity of non-β-lactam agents (amikacin and ciprofloxacin) significantly decreased during the time period of the study. (cmac-journal.ru)
  • Resistant to cephalexin and cefoxitin was 5.88% and 2.94%, respectively. (ac.ir)
  • Antimicrobial resistant microorganisms are found in people, animals and the environment and can spread globally. (who.int)
  • This resistance to antimicrobial medicines is happening in all parts of the world for a broad range of microorganisms with an increasing prevalence that threatens human and animal health. (who.int)