Arterial pressureReduced systemic vascular resistance and bloodVasodilationVasoconstrictionMmHgPerfusionSVRIHypotensionReductionPeripheralDecreaseDecreasesHypertensionLeft ventricularAfterloadReducesEndothelialRenal blooIntracranial pressureSystolic pressureAntihypertensiveInflammationExertsConcomitantAlterationsIdiopathicRespiratory rateUltrasonographyAcuteCarotidMean arterial blood prUprightCardiovascularHemodynamic parametersDeeperDiseasesClinicalEffectsReflectionLung
Arterial pressure11
- Arteriolar relaxation reduces systemic vascular resistance, systolic arterial pressure and mean arterial pressure (afterload). (nih.gov)
- Because arterial pressure is determined by cardiac output, venous pressure and systemic vascular resistance ( Click here for more details ), a reduction in any of these variables can lead to hypotension. (cvpharmacology.com)
- Verapamil HCl regularly reduces arterial pressure at rest and at a given level of exercise by dilating peripheral arterioles and reducing the total peripheral resistance (afterload) against which the heart works. (drugs.com)
- The diagnosis is confirmed regardless of the pulmonary arterial pressure, as long as it is accompanied by a right-to-left shunt and absence of congenital heart disease. (medscape.com)
- This leads to a decrease in mean arterial pressure and further decrease in cardiac output. (renalandurologynews.com)
- Mean arterial pressure (MAP), heart rate (HR), systemic vascular resistance index (SVRI), cardiac index (CI), and stroke volume index (SVI) were measured continuously during − 0, − 20, and − 40 mmHg LBNP. (springer.com)
- Inhaled nitric oxide (iNO) selectively reduces pulmonary vascular resistance and pulmonary arterial pressure without affecting systemic arterial pressure. (bmj.com)
- The left radial artery was cannulated for direct arterial pressure monitoring and ABG analysis intra and post operatively. (ispub.com)
- Because small arteries and arterioles normally have a high degree of smooth muscle tone , these drugs are effective in dilating these resistance vessels, decreasing systemic vascular resistance, and lowering arterial pressure. (cvpharmacology.com)
- The fall in arterial pressure leads to reflex cardiac stimulation ( baroreceptor -mediated tachycardia). (cvpharmacology.com)
- The measurement of brachial artery pressure is not indicative of the uterine arterial blood pressure because the uterine arterial pressure can be extremely low, even when the blood pressure measurement of the arm is normal. (medscape.com)
Reduced systemic vascular resistance and blood1
- Residual cardiac defects in combination with the circulatory changes observed during pregnancy (increased cardiac output and reduced systemic vascular resistance and blood pressure) may affect pregnancy in women with corrected tetralogy of Fallot. (bmj.com)
Vasodilation5
- Fenoldopam causes arterial/arteriolar vasodilation leading to a decrease in blood pressure by activating peripheral D1 receptors. (wikipedia.org)
- Reduced systemic vascular resistance because of loss of sympathetic tone caused by drugs, autonomic dysfunction, or vasodilation caused by sepsis (septic shock) or anaphylaxis. (cvpharmacology.com)
- Therefore, hypotension is normally a result of a combination of factors such as bradycardia, vasodilation (decreases in systemic vascular resistance), and decreases in cardiac contractility which in turn will reduce stroke volume and cardiac output. (vin.com)
- Other measurable effects include a vasoconstriction of cerebral blood vessels, vasodilation of systemic blood vessels and reduced blood flow. (deeperblue.com)
- The combined effects of systemic vasodilation and cerebral vasoconstriction cause a restriction in blood flow to the brain. (deeperblue.com)
Vasoconstriction3
- Reduction in myocardial contractility results in decreased cardiac output, hypotension, systemic vasoconstriction, and cardiac ischemia. (medscape.com)
- The pathogenesis of arterial hypertension often involves a rise in systemic vascular resistance (vasoconstriction and vascular remodeling) and impairment of salt excretion in the kidney (inappropriate salt retention despite elevated blood pressure). (nature.com)
- It causes vasoconstriction (narrowing of the interior channel of blood vessels), increases heart rate, increases blood pressure, facilitates glycogenolysis (coversion of glycogen to glucose ), and elevates the blood sugar level. (newworldencyclopedia.org)
MmHg4
- For an adult, hypotension exists when the systolic pressure is less than 90 mmHg and the diastolic pressure is less than 60 mmHg. (cvpharmacology.com)
- 12 Changing from a high-sodium diet (4,000 mg/day) to a low-sodium diet (2,000 mg/day) over several years can lower blood pressure by as much as 10 mmHg. (uspharmacist.com)
- Reducing body weight by as little as 10% through a sensible exercise program (i.e., moderate physical activity 30 minutes per day at least five times a week) may decrease blood pressure by 5 to 15 mmHg. (uspharmacist.com)
- The pulse was 88 per minute and the blood pressure 110/70 mmHg. (ispub.com)
Perfusion3
- By definition, blood pressure (BP) is the force that the flow of blood exerts on the walls of the vessels and what drives tissue perfusion. (vin.com)
- It is believed that a mean arterial blood pressure of 70 mm Hg is required for adequate perfusion of vital organs such as the brain, heart and kidneys. (vin.com)
- Although there is a controversy as to the exact difference, if any, between noninvasive recording and actual brain perfusion, some theories support correcting blood pressure in the sitting position to account for a gravitational effect on the column of blood between the site of measurement and the brain. (renalandurologynews.com)
SVRI1
- Values of systemic vascular resistance index (SVRI), heart rate (HR), pulmonary artery wedge pressure (PAWP) and cardiac index (CI) at hours 3, 6, 9 and 12 of the experiment were compared. (nel.edu)
Hypotension1
- Hypotension is a physiologic state in which the arterial blood pressure is abnormally low. (cvpharmacology.com)
Reduction8
- to cause a reduction in systemic vascular resistance. (wikipedia.org)
- The quantitative relationship between plasma verapamil concentrations and blood pressure reduction has not been fully characterized. (drugs.com)
- The blood pressure reduction during the first day is due to an independent mechanism, e.g. a decrease in sympathetic nervous tone. (portlandpress.com)
- With 20% reduction in blood volume, gain for cardiac output fell but gain for systemic vascular resistance rose and its phase-lag became shorter, so that gain for blood pressure was unaltered. (portlandpress.com)
- The enhanced gain for systemic vascular resistance was not sustained with 35% reduction in blood volume, so that gain for blood pressure fell. (portlandpress.com)
- Because the freediver performs a breath-hold at a large lung volume with relaxed respiratory muscles there is an increase in intrathoracic pressure that results in a reduction of cardiac output and intrathoracic blood volume. (deeperblue.com)
- Japanese tub bathing, which typically involves sitting in hot water to shoulder depth, exposes the bather both to heat and to water pressure, which results in an increase in stroke volume and cardiac output with a reduction in systemic vascular resistance. (bmj.com)
- Acute exposure to COV resulted in a reduction in mean arterial and diastolic blood pressures 1 and 28 d after exposure, changes in nitrate-nitrite and H(2)O(2) levels, and in the expression of transcripts and proteins that regulate inflammation, vascular remodeling, and the synthesis of NO in the heart and kidneys. (cdc.gov)
Peripheral7
- Phosphine is a respiratory tract irritant that attacks primarily the cardiovascular and respiratory systems causing peripheral vascular collapse, cardiac arrest and failure, and pulmonary edema. (cdc.gov)
- The principal pharmacological action of ISMN and all organic nitrates in general is relaxation of vascular smooth muscle, producing dilatation of peripheral arteries and veins, especially the latter. (nih.gov)
- Dilatation of the veins promotes peripheral pooling of blood, decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure and pulmonary capillary wedge pressure (preload). (nih.gov)
- The pathophysiology behind hypertension in the elderly is a complex process that is not entirely understood, but it is attributed to an increase in peripheral vascular resistance caused by decreased elasticity and increased stiffness due to smooth muscle hypertrophy in arterial walls. (uspharmacist.com)
- The principal pharmacological action of isosorbide dinitrate is relaxation of vascular smooth muscle and consequent dilatation of peripheral arteries and veins, especially the latter. (prescriptiondrugs.com)
- Arterial blood gas levels (through an indwelling line [eg, umbilical arterial catheter or preductal peripheral arterial line]): To assess the pH, partial pressure of carbon dioxide (PaCO 2 ) and the partial pressure of oxygen (PaO 2 ) which might be higher in the preductal arterial line. (medscape.com)
- Diabetes Mellitus (DM) Diabetes mellitus is impaired insulin secretion and variable degrees of peripheral insulin resistance leading to hyperglycemia. (msdmanuals.com)
Decrease6
- The decrease in blood pressure over the first 24 h period was equal. (portlandpress.com)
- 6. It is concluded that sodium loss contributes to the decrease in blood pressure on the second day of hospital admission and after. (portlandpress.com)
- There is a progressive decrease in sympathetic activity, blood pressure (BP), stroke volume, heart rate, cardiac output, and systemic vascular resistance, during deeper NREM sleep stages [ 4 ]. (hindawi.com)
- 2. With acute, isohaemic increase in blood volume by 20% and 40% the only consistent trend was a decrease in gain for systemic vascular resistance. (portlandpress.com)
- Both the systolic and diastolic blood pressures decrease until mid pregnancy, with gradual recovery to nonpregnant values by late gestation. (medscape.com)
- [ 4 ] The blood pressure decrease likely occurs because of decreased vascular resistance. (medscape.com)
Decreases1
- Blockade of the alpha 1 receptor decreases urethral resistance and may relieve the obstruction and BPH symptoms. (nih.gov)
Hypertension6
- The objective of this study was to examine the changes of blood pressure and hemodynamic parameters after oral magnesium supplementation in patients with essential hypertension. (nih.gov)
- According to the Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7), the SBP should be the primary target for diagnosis and treatment of hypertension in the elderly ( TABLE 1 ). (uspharmacist.com)
- This article is a review of exciting, recently generated genetic, biochemical and clinical data from studies that have examined the importance of the tissue kallikrein-kinin system in protection from hypertension, vascular remodeling and renal fibrosis. (nature.com)
- Development of novel therapeutic approaches to bolster kinin activity in the vascular wall and in specific compartments in the kidney might be a highly effective strategy for the treatment of hypertension and its complications, including cardiac hypertrophy and renal failure. (nature.com)
- In contrast to adult primary pulmonary hypertension, the newborn syndrome is not defined by a specific pressure of the pulmonary circulation. (medscape.com)
- In relation to the systemic condition, women presented more systemic alterations in comparison with men, showing higher prevalence of diabetes and hypertension. (bvsalud.org)
Left ventricular1
- In this group, arterial blood pressure was low, and the cardiac index, systemic vascular resistance index, and left ventricular stroke work index were all reduced, suggesting decreased cardiac contractility and blood vessel tone. (jci.org)
Afterload2
- 1 Premature infants with respiratory distress syndrome (RDS) may have elevated pulmonary vascular resistance, which may negatively affect the afterload-sensitive premature right ventricle, diminishing cardiac output. (bmj.com)
- Stroke volume depends on preload (venous return to the heart), afterload (resistance to systolic ejection) and contractility (inotropy or strength of contraction). (vin.com)
Reduces2
- Hypovolemia caused by hemorrhage or dehydration (reduces venous pressure and cardiac output). (cvpharmacology.com)
- Impaired venous return caused by postural changes, gravitational forces, or venous obstruction (reduces venous pressure and cardiac output). (cvpharmacology.com)
Endothelial2
- Repetitive apneic episodes disrupt the normal physiologic function and trigger sympathetic activation, vascular endothelial dysfunction, increased oxidative stress, inflammation, increased platelet aggregability, and metabolic dysregulation. (hindawi.com)
- The vascular endothelium produces a number of important substances including endothelial-derived relaxing factor or nitric oxide, endothelin-1, prostacyclin, and tissue plasminogen activator. (health.am)
Renal bloo1
- High flow oxygen resulting in hyperoxia also has the potential to cause significant adverse cardiovascular effects with increased systemic vascular resistance and blood pressure, decreased cardiac output and reduced coronary, cerebral and renal blood flow. (bmj.com)
Intracranial pressure2
- it also allows for improved venous and cerebrospinal fluid drainage, potentially lowering intracranial pressure. (renalandurologynews.com)
- Intraoperatively, the patient received dilantin 100mg, dexamethasone 8mg, mannitol 40gm and xylocard 60mg to lower the intracranial pressure and make the brain lax for the surgeon. (ispub.com)
Systolic pressure1
- 7 Both systolic blood pressure (SBP) and diastolic blood pressure (DBP) rise until about 55 years of age, after which the systolic pressure continues to rise almost linearly and the diastolic shows little to no change or declines by the sixth decade of life. (uspharmacist.com)
Antihypertensive1
- In humans, angiotensin-converting enzyme inhibitors, a potent class of antihypertensive agents, lower blood pressure at least partially by favoring enhanced kinin accumulation in plasma and target tissues. (nature.com)
Inflammation2
- The treatment markedly improved clinical and hemodynamic parameters and decreased blood plasma markers of vascular fibrosis, injury and inflammation. (nature.com)
- The pathobiology of pulmonary vascular disease (PVD) and PAH is complex, multifactorial and driven by inflammation and metabolic dysfunction 1 . (nature.com)
Exerts1
Concomitant1
- 4. Thus control of blood pressure by the carotid sinus reflex is remarkably unaffected by acute change in blood volume, and is impaired only when there is depression of gain for cardiac output without a concomitant rise in gain for systemic vascular resistance. (portlandpress.com)
Alterations1
- When the patient is moved after the induction of general anesthesia, the anesthesiologist must be aware of any blood pressure alterations and ensure a safe systemic blood pressure prior to any patient movement. (renalandurologynews.com)
Idiopathic1
- Studies establishing effectiveness included patients with NYHA Functional Class II-IV symptoms and etiologies of idiopathic or heritable PAH (58%), PAH associated with congenital systemic-to-pulmonary shunts (23%), or PAH associated with connective tissue diseases (19%) [see Clinical Studies ]. (rxlist.com)
Respiratory rate1
- Heart rate, respiratory rate, arterial blood pressures, and cardiac output remained similar to preanesthetic values throughout TIVA. (avma.org)
Ultrasonography1
- Blood pressure is measured either indirectly (oscillometric sphygmomanometry or Doppler ultrasonography) or directly when a catheter is placed in an artery and connected to a pressure transducer that allows constant and continuous evaluation of systolic, mean and diastolic blood pressure. (vin.com)
Acute1
- 1. The effects of acute blood volume change in conscious rabbits on a.c. gain of the carotid baroreceptor reflex with respect to heart rate, blood pressure, cardiac output and systemic vascular resistance were studied. (portlandpress.com)
Carotid1
- The Asklepios study is a longitudinal population study including 2026 apparently healthy middle-aged subjects at inclusion (52% females), who underwent two rounds of measurements of carotid pressure (applanation tonometry) and central flow (ultrasound), with a follow-up time of 10.14 ± 1.39 years. (atlantis-press.com)
Mean arterial blood pr1
- It is generally agreed that the onset of hypocapnia causes tachycardia, increased cardiac output and reduced systemic vascular resistance and mean arterial blood pressure. (deeperblue.com)
Upright3
- In awake patients, transitioning from the supine to upright position causes an increase in systemic vascular resistance (SVR) and systemic blood pressure. (renalandurologynews.com)
- Systemic and forearm vascular resistance changes after upright bicycle exercise in man. (elsevierpure.com)
- Dive into the research topics of 'Systemic and forearm vascular resistance changes after upright bicycle exercise in man. (elsevierpure.com)
Cardiovascular1
- The beneficial actions of kinins in renal and cardiovascular disease are largely mediated by nitric oxide and prostaglandins, and extend beyond their recognized role in lowering blood pressure to include cardioprotection and nephroprotection. (nature.com)
Hemodynamic parameters1
- The participants were asked to consume (daily at home) 300 mg of oral magnesium-oxide supplementation product for one month and to have their blood pressure and hemodynamic parameters (thoracic fluid content, stroke volume, stroke index, cardiac output, cardiac index, acceleration index, left cardiac work index and systemic vascular resistance index, heart rate) measured in the hospital before and after the intervention. (nih.gov)
Deeper1
- As the freediver descends deeper, the partial pressures of gases in the lungs increase due to the increased compression. (deeperblue.com)
Diseases1
- It may also technically justify either possible failures or deficiencies in dental treatment, for example, by describing the presence of systemic diseases which modify the host's response. (bvsalud.org)
Clinical3
- Anamnesis and clinicai examination accomplished in the periodontal clinic can establish some demographic, clinical and systemic disease patterns related to the presence of the periodontal disease in patients seeking treatment at dental school clinics. (bvsalud.org)
- The aim of this study is to evaluate the clinical files of patients to detect the presence and type of existing periodontal disease, as well as to verify the presence of risk factors such as altered systemic condition and the use of medicines to correlate them with gender and age. (bvsalud.org)
- Additionally, the study aimed to identify some elements of the periodontal and systemic profile correlated to demographic data (gender and age) of the patients undergoing periodontal treatment at the Center of High Education of Campos Gerais (short Cescage), in Ponta Grossa (Parana, Brazil), through clinical record analysis. (bvsalud.org)
Effects2
Reflection1
- Wave reflection decreased with ageing, whereas resistance increased in women and decreased in men. (atlantis-press.com)
Lung2
- We aimed to assess the feasibility of nebulizing a high-dose of poractant alfa with the eFlow-Neos investigational vibrating-membrane nebulizer in newborn piglets on nasal continuous positive airway pressure (nCPAP) and to determine whether this intervention would yield therapeutic lung doses of phospholipids. (bvsalud.org)
- COV treatment did not affect lung vascular permeability. (cdc.gov)