• By definition, blood pressure (BP) is the force that the flow of blood exerts on the walls of the vessels and what drives tissue perfusion. (vin.com)
  • It is believed that a mean arterial blood pressure of 70 mm Hg is required for adequate perfusion of vital organs such as the brain, heart and kidneys. (vin.com)
  • Although there is a controversy as to the exact difference, if any, between noninvasive recording and actual brain perfusion, some theories support correcting blood pressure in the sitting position to account for a gravitational effect on the column of blood between the site of measurement and the brain. (renalandurologynews.com)
  • Phosphine is a respiratory tract irritant that attacks primarily the cardiovascular and respiratory systems causing peripheral vascular collapse, cardiac arrest and failure, and pulmonary edema. (cdc.gov)
  • The principal pharmacological action of ISMN and all organic nitrates in general is relaxation of vascular smooth muscle, producing dilatation of peripheral arteries and veins, especially the latter. (nih.gov)
  • Dilatation of the veins promotes peripheral pooling of blood, decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure and pulmonary capillary wedge pressure (preload). (nih.gov)
  • The pathophysiology behind hypertension in the elderly is a complex process that is not entirely understood, but it is attributed to an increase in peripheral vascular resistance caused by decreased elasticity and increased stiffness due to smooth muscle hypertrophy in arterial walls. (uspharmacist.com)
  • The principal pharmacological action of isosorbide dinitrate is relaxation of vascular smooth muscle and consequent dilatation of peripheral arteries and veins, especially the latter. (prescriptiondrugs.com)
  • Arterial blood gas levels (through an indwelling line [eg, umbilical arterial catheter or preductal peripheral arterial line]): To assess the pH, partial pressure of carbon dioxide (PaCO 2 ) and the partial pressure of oxygen (PaO 2 ) which might be higher in the preductal arterial line. (medscape.com)
  • Diabetes Mellitus (DM) Diabetes mellitus is impaired insulin secretion and variable degrees of peripheral insulin resistance leading to hyperglycemia. (msdmanuals.com)
  • Blockade of the alpha 1 receptor decreases urethral resistance and may relieve the obstruction and BPH symptoms. (nih.gov)
  • The objective of this study was to examine the changes of blood pressure and hemodynamic parameters after oral magnesium supplementation in patients with essential hypertension. (nih.gov)
  • According to the Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7), the SBP should be the primary target for diagnosis and treatment of hypertension in the elderly ( TABLE 1 ). (uspharmacist.com)
  • This article is a review of exciting, recently generated genetic, biochemical and clinical data from studies that have examined the importance of the tissue kallikrein-kinin system in protection from hypertension, vascular remodeling and renal fibrosis. (nature.com)
  • Development of novel therapeutic approaches to bolster kinin activity in the vascular wall and in specific compartments in the kidney might be a highly effective strategy for the treatment of hypertension and its complications, including cardiac hypertrophy and renal failure. (nature.com)
  • In contrast to adult primary pulmonary hypertension, the newborn syndrome is not defined by a specific pressure of the pulmonary circulation. (medscape.com)
  • In relation to the systemic condition, women presented more systemic alterations in comparison with men, showing higher prevalence of diabetes and hypertension. (bvsalud.org)
  • In this group, arterial blood pressure was low, and the cardiac index, systemic vascular resistance index, and left ventricular stroke work index were all reduced, suggesting decreased cardiac contractility and blood vessel tone. (jci.org)
  • 1 Premature infants with respiratory distress syndrome (RDS) may have elevated pulmonary vascular resistance, which may negatively affect the afterload-sensitive premature right ventricle, diminishing cardiac output. (bmj.com)
  • Stroke volume depends on preload (venous return to the heart), afterload (resistance to systolic ejection) and contractility (inotropy or strength of contraction). (vin.com)
  • Repetitive apneic episodes disrupt the normal physiologic function and trigger sympathetic activation, vascular endothelial dysfunction, increased oxidative stress, inflammation, increased platelet aggregability, and metabolic dysregulation. (hindawi.com)
  • The vascular endothelium produces a number of important substances including endothelial-derived relaxing factor or nitric oxide, endothelin-1, prostacyclin, and tissue plasminogen activator. (health.am)
  • 7 Both systolic blood pressure (SBP) and diastolic blood pressure (DBP) rise until about 55 years of age, after which the systolic pressure continues to rise almost linearly and the diastolic shows little to no change or declines by the sixth decade of life. (uspharmacist.com)
  • The treatment markedly improved clinical and hemodynamic parameters and decreased blood plasma markers of vascular fibrosis, injury and inflammation. (nature.com)
  • The pathobiology of pulmonary vascular disease (PVD) and PAH is complex, multifactorial and driven by inflammation and metabolic dysfunction 1 . (nature.com)
  • The operator exerts pressure with both hands in order to compress the uterus between the two hands and stop the hemorrhage (Figure 1). (glowm.com)
  • Studies establishing effectiveness included patients with NYHA Functional Class II-IV symptoms and etiologies of idiopathic or heritable PAH (58%), PAH associated with congenital systemic-to-pulmonary shunts (23%), or PAH associated with connective tissue diseases (19%) [see Clinical Studies ]. (rxlist.com)
  • Heart rate, respiratory rate, arterial blood pressures, and cardiac output remained similar to preanesthetic values throughout TIVA. (avma.org)
  • Blood pressure is measured either indirectly (oscillometric sphygmomanometry or Doppler ultrasonography) or directly when a catheter is placed in an artery and connected to a pressure transducer that allows constant and continuous evaluation of systolic, mean and diastolic blood pressure. (vin.com)
  • The Asklepios study is a longitudinal population study including 2026 apparently healthy middle-aged subjects at inclusion (52% females), who underwent two rounds of measurements of carotid pressure (applanation tonometry) and central flow (ultrasound), with a follow-up time of 10.14 ± 1.39 years. (atlantis-press.com)
  • The beneficial actions of kinins in renal and cardiovascular disease are largely mediated by nitric oxide and prostaglandins, and extend beyond their recognized role in lowering blood pressure to include cardioprotection and nephroprotection. (nature.com)
  • The participants were asked to consume (daily at home) 300 mg of oral magnesium-oxide supplementation product for one month and to have their blood pressure and hemodynamic parameters (thoracic fluid content, stroke volume, stroke index, cardiac output, cardiac index, acceleration index, left cardiac work index and systemic vascular resistance index, heart rate) measured in the hospital before and after the intervention. (nih.gov)
  • As the freediver descends deeper, the partial pressures of gases in the lungs increase due to the increased compression. (deeperblue.com)
  • It may also technically justify either possible failures or deficiencies in dental treatment, for example, by describing the presence of systemic diseases which modify the host's response. (bvsalud.org)
  • Anamnesis and clinicai examination accomplished in the periodontal clinic can establish some demographic, clinical and systemic disease patterns related to the presence of the periodontal disease in patients seeking treatment at dental school clinics. (bvsalud.org)
  • The aim of this study is to evaluate the clinical files of patients to detect the presence and type of existing periodontal disease, as well as to verify the presence of risk factors such as altered systemic condition and the use of medicines to correlate them with gender and age. (bvsalud.org)
  • Additionally, the study aimed to identify some elements of the periodontal and systemic profile correlated to demographic data (gender and age) of the patients undergoing periodontal treatment at the Center of High Education of Campos Gerais (short Cescage), in Ponta Grossa (Parana, Brazil), through clinical record analysis. (bvsalud.org)
  • Most phosphine exposures occur by inhalation of the gas or ingestion of metallic phosphides, but dermal exposure to phosphides can also cause systemic effects. (cdc.gov)
  • Phosphine gas produces no adverse effects on the skin or eyes, and contact does not result in systemic toxicity. (cdc.gov)
  • Wave reflection decreased with ageing, whereas resistance increased in women and decreased in men. (atlantis-press.com)
  • We aimed to assess the feasibility of nebulizing a high-dose of poractant alfa with the eFlow-Neos investigational vibrating-membrane nebulizer in newborn piglets on nasal continuous positive airway pressure (nCPAP) and to determine whether this intervention would yield therapeutic lung doses of phospholipids. (bvsalud.org)
  • COV treatment did not affect lung vascular permeability. (cdc.gov)