• In the simplest case, the difference between two haplotypes is assessed by counting the number of locations where they have different bases: this is referred to as the number of substitutions (other kinds of differences between haplotypes can also occur, for example, the insertion of a section of nucleic acid in one haplotype that is not present in another). (wikipedia.org)
  • The present invention relates to a method for the specific detection and/or identification of Enterococcus species, in particular Enterococcus faecalis and/or Enterococcus faecium, using new nucleic acid sequences derived from the ITS (Internal Transcribed Spacer) region. (justia.com)
  • The present invention relates also to said new nucleic acid sequences derived from the ITS region, between the 16S and 23S ribosomal ribonucleic acid (rRNA) or rRNA genes, to be used for the specific detection and/or identification of Enterococcus species, in particular of Enterococcus faecalis and/or Enterococcus faecium, in a biological sample. (justia.com)
  • It relates also to nucleic acid primers to be used for the amplification of said spacer region of Enterococcus species in a sample. (justia.com)
  • vi)a nucleic acid sequence according to any of (i) and (ii) which is degenerate as a result of the genetic code. (allindianpatents.com)
  • This invention provides an APP-cleaving protein and related nucleic acid compounds. (everypatent.com)
  • Kunitz-like domain"--A protease inhibitor similar to soybean trypsin inhibitor or a nucleic acid sequence encoding a protease inhibitor which is similar to the soybean trypsin inhibitor. (everypatent.com)
  • The present invention provides novel solution phase hybridization-based methods for detecting and quantitating nucleic acid analytes. (toddbilleci.com)
  • Based on the famous ""mfold"", the UNAFold software package is an integrated collection of programs that simulate nucleic acid folding and hybridization, and its melting pathways for one or two single-stranded molecules. (rpi.edu)
  • At present, it is still a long and expensive process to sequence the entire DNA of an organism (its genome). (wikipedia.org)
  • The completion of the first human genome drafts (Yamey 2000 ) was just a start of the modern DNA sequencing era which resulted in further invention, improved development toward new advanced strategies of high-throughput DNA sequencing, so called the " high-throughput next generation sequencing " (HT-NGS). (springer.com)
  • For the future direction, we need the in-depth genome sequence information and analysis for most of the mammals, including human to fully understand genome variation of economic traits, genetic susceptibility to diseases, and pharmacogenomics of drug response. (springer.com)
  • Year 2011 is celebrated as the 10th anniversary since the human genome was first sequenced ( www.nature.com/natureconferences/hg10years/index.html ). (springer.com)
  • During this period, tremendous success has been achieved in the fields of decoding of human genome, technological advancement of new era of human genome applications, toward personalized genomes and discovery of rare variants, leveraging genome sequencing to impact on cancer researches and mammalian evolution and population structure. (springer.com)
  • The sequencing of the D.melanogaster genome revealed an unexpected small number of genes (~ 14,000) indicating that mechanisms acting on generation of transcript diversity must have played a major role in the evo. (biomedcentral.com)
  • The advantage claimed for using hybridization rather than gene sequencing was that it was based on the entire genotype, rather than on particular sections of DNA. (wikipedia.org)
  • The present invention relates to methods, kits and systems for predicting the benefit from inclusion of taxane in a chemotherapy regimen based on the measurements of gene expression levels in tumor samples of breast cancer patients. (justia.com)
  • Amici argue that the problem with plaintiffs' zealous attack on gene patents in response to 'what they perceive to be a significant public health concern,' however justified by 'Myriad's patent enforcement and business practices,' is that the strategy, and asked-for remedy would invalidate 'a host of patents claiming gene-based inventions, often referred to as 'gene patents' and indeed many other technologies based on making and analyzing DNA. (patentdocs.org)
  • The argument is supported by a thorough analysis of the facts relating to the effects, good and bad, of gene patents on biotechnology, genetics, and medicine. (patentdocs.org)
  • More specifically, the present invention concerns altering tolerance in plants to various environmental stresses and to increasing seed yield by modifying plant haemoglobin gene expression and/or by modifying plant haemoglobin protein levels. (allindianpatents.com)
  • The present invention provides a simple and robust human liver cell-based system in which persistent hepatitis C infection, persistent hepatitis B infection or ethanol exposure induces a clinical Prognostic Liver Signature (PLS) high-risk gene signature. (sumobrain.com)
  • In a comparisonof the first two bacterial genomes sequenced, Mushegian and Kooninprojected that the 256 orthologous genes shared by the Gram negativeHaemophilus influenzae and the Gram positive M. genitalium genomes area close approximation of a minimal gene set for bacterial life(2). (fullblog.com.ar)
  • In1999 some of the present inventors reported the first use of globaltransposon mutagenesis to experimentally determine the genes notessential for laboratory growth of M. genitalium{A). Since then therehave been numerous other experimental determinations of bacterialessential gene sets using our approach and other methods such as sitedirected gene knockouts and antisense RNA (5- 12). (fullblog.com.ar)
  • gene in a series of tissue types, throughout stages of development or cellular However, asymmetric PCR is the most cost effective method for ssDNA production. (nervegarden.com)
  • With the ongoing developments of high throughput sequencing machines and advancement of modern bioinformatics tools at unprecedented pace, the target goal of sequencing individual genomes of living organism at a cost of $1,000 each is seemed to be realistically feasible in the near future. (springer.com)
  • Due to the large number of viral genomes now sequenced it is very imp. (biomedcentral.com)
  • Primer Design Design three adjacent primers from your sequence (priming outwards from the sequence). (nervegarden.com)
  • primers that bind specifically to the known sequence and point in opposite http://www.bio.davidson.edu/courses/genomics/method/NestedPCR.html). (nervegarden.com)
  • Within the known sequence, TAIL-PCR uses a nested pair of primers with differing annealing temperatures. (nervegarden.com)
  • Heterogeneous cDNAs can be amplified with PCR by appending known sequences to one or both ends of the cDNA so primers with known sequences can be used to amplify the heterogeneous cDNAs. (github.io)
  • This invention concerns affinity tools for oligomeric forms of tau protein. (justia.com)
  • Since the structural amount is binding, assistive introns around the physiological protein can be the method either to the lower or the longitudinal non-ignorable sets of joint model. (scoutconnection.com)
  • The1999 report by some of the present inventors on the essential microbialgene for M. genitalium and its closest relative, Mycoplasma pneumoniae,mapped ~2200 transposon insertion sites in these two species, andidentified 130 putatively non-essential M. genitalium protein-codinggenes or M. pneumoniae orthologs of M. genitalium genes. (fullblog.com.ar)
  • 2. Henzel WJ, Billeci TM, Stults, JT, Wong SC, Grimley C and Watanabe C: Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases. (toddbilleci.com)
  • 4. Henzel WJ, Billeci TM, Stults JT, Wong S, Grimley C and Watanabe C: Identifying proteins at the femtomole level by molecular mass searching of peptide fragments in a protein sequence database. (toddbilleci.com)
  • Haplotypes of individuals of closely related, yet different, taxa are also determined. (wikipedia.org)
  • 3. Asymmetric PCR can be used to form single stranded DNA from double stranded DNA, which is then used for DNA sequencing in the mutagenesis method. (nervegarden.com)
  • The compounds of this invention will further the characterization of neurological diseases such as Alzheimer's disease and Down's syndrome. (everypatent.com)
  • The present invention also relates to specific compounds that have been identified, using such screening methods, as useful in the treatment and/or the prevention of HCC/cirrhosis. (sumobrain.com)
  • The particular sequence found in a given organism is referred to as its haplotype. (wikipedia.org)
  • Thisinvention relates, e.g., to the identification of non-essential genesof bacteria, and of a minimal set of genes required to supportviability of a free-living organism. (fullblog.com.ar)
  • The present invention discloses an asymmetric PCR amplification method, its special primer and application, aims to provide a simple, effective PCR amplification for preparation of single-stranded product. (nervegarden.com)
  • Asymmetric PCR: A dot blot is a The creation of amplification methods to generate single-stranded DNA (1,2) has represented a major advance in development of PCR technology. (nervegarden.com)
  • a) Used for generating double-stranded copies for DNA sequence (b) Used for generating single-stranded copies for DNA sequence (c) Both a and b (d) None of the above. (nervegarden.com)
  • Single-stranded DNA produced can be … (1), Multiplex PCR: The first PCR amplifies a sequence as seen in any PCR experiment. (nervegarden.com)
  • Single-stranded target DNAs have been efficiently used in the studies of micro-array hybridization (4-7) and direct sequencing of DNA (1,8). (nervegarden.com)
  • Molecular phylogenetics (/məˈlɛkjʊlər ˌfaɪloʊdʒəˈnɛtɪks, mɒ-, moʊ-/) is the branch of phylogeny that analyzes genetic, hereditary molecular differences, predominantly in DNA sequences, to gain information on an organism's evolutionary relationships. (wikipedia.org)
  • In the period of 1974-1986, DNA-DNA hybridization was the dominant technique used to measure genetic difference. (wikipedia.org)
  • In general, these are considered superior for evolutionary studies, since the actions of evolution are ultimately reflected in the genetic sequences. (wikipedia.org)
  • This landmark ruling opened enormous omline bilities for the commercial growth of genetic en- gineering. (binaryoptionsforex625.com)
  • Director Lorne Townend uses three-dimensional (3D) and four-dimensional (4D) ultrasound imaging and microscopy to depict twin development , genetic and epigenetic variations in the fetuses, and methods of fetal survival in the confines of the womb. (asu.edu)
  • It relates to the field of neurodegeneration, more particularly to the field of tau-related diseases and tauopathy. (justia.com)
  • The invention further provides methods for the detection of aggregated tau, for the diagnosis of diseases involving aggregated tau, and for the identification of compositions interfering with the formation and/or stability of tau aggregates. (justia.com)
  • Moreover, use of the invention may result in treatments for these or other related diseases. (everypatent.com)
  • Obesity-related diseases including heart disease, stroke, type 2 diabetes, and cancer are a leading cause of preventable death. (cshlpress.com)
  • Detection may be by a variety of methods including hybridization based or sequencing. (patsnap.com)
  • Sputum smears microscopy and special staining (Ziehl-Neelsen) for detection of acid-fast bacilli with light microscope can be fast, easy and cost-effective method to detect Mycobacterium tuberculosis . (iomcworld.org)
  • This method includes the detection of tuberculosis with and without drug resistance. (iomcworld.org)
  • Since tuberculosis is related with the immune system, the immune function detection is done to detect presence of a specific cellular immune response directed towards mycobacterial antigens in the absence of clinical infection. (iomcworld.org)
  • system for DNA replication that allows a "target" DNA sequence to be In medical science, PCR is used for the detection of infectious organisms and the detection of mutation in various genes. (nervegarden.com)
  • 1. A purified protease which comprises the amino acid sequence SEQ ID NO:1, or a functional equivalent thereof produced by conservative amino acid alterations which result in a protease which exhibits the same biological, biochemical, chemical, physical and structural properties of the protease of SEQ ID NO:1. (everypatent.com)
  • Typical molecular systematic analyses require the sequencing of around 1000 base pairs. (wikipedia.org)
  • A mixed-methods systematic review was conducted. (bvsalud.org)
  • Our physics remain found by biological( Culture Survey, Organizational Analytics) and strong methods( minutes, formula of borate electropherograms, P regimes). (drpulley.co.uk)
  • This review discusses the various diagnostic methods which include the conventional methods as well as the newer molecular methods along with their advantages and disadvantages. (iomcworld.org)
  • The most commonly used screening method, chest x-ray is not sufficient as it has low specificity in detecting pulmonary tuberculosis [ 5 ]. (iomcworld.org)
  • The high-throughput - next generation sequencing (HT-NGS) technologies are currently the hottest topic in the field of human and animals genomics researches, which can produce over 100 times more data compared to the most sophisticated capillary sequencers based on the Sanger method. (springer.com)
  • The present invention generally relates to the field of Fluorescence Quenching Immunoassays. (trea.com)
  • Along with laboratory investigations, field trips will help relate the chemistry concepts to the world around us. (jrosspeters.com)
  • The present invention provides a new enzyme which is structurally different from those previously described and which will cleave APP to generate amyloidogenic fragments the size expected of a Met.sub.596 -Asp.sub.597 cleavage. (everypatent.com)
  • In different aspects, irradiator apparatus may be configured as disposable devices, and/or used in combination with one or more microfluidic or sensing components, for a variety of medical/laboratory/diagnostic methods and instrumentation implementations. (patentsencyclopedia.com)
  • Patients with pulmonary tuberculosis present with chronic cough with excess sputum production, loss of weight and appetite and sometimes haemoptysis. (iomcworld.org)
  • Cold Spring Harbor, NY -- Cold Spring Harbor Laboratory Press (CSHLP) announced the release of Next-Generation Sequencing in Medicine, available on its website in hardcover and ebook formats. (cshlpress.com)
  • Apparatuses and methods for medical monitoring physiological characteristic values such as blood glucose levels for the treatment of diabetes, are presented. (patsnap.com)
  • Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices. (patsnap.com)
  • Irradiation methods and apparatus configured to deliver power, via electromagnetic fields at a variety of frequencies and power levels, in a localized fashion to a target area. (patentsencyclopedia.com)
  • Such methods and apparatus are particularly useful in a wide variety of processes involving chemical and/or physical interactions in connection with a sample of interest located in the thin region. (patentsencyclopedia.com)
  • The invention also provides methods, materials and assays. (everypatent.com)
  • The present invention concerns a method for altering growth characteristics of plants, in particular a method for altering stress tolerance and yield in plants. (allindianpatents.com)
  • The drawback of this method is during clinical phase, the specific immune response won't give a direct evidence of viable bacilli. (iomcworld.org)
  • The book openaccess release of plasmid methods during stroke is their bacterial bookSignature in predicting site within profiles. (steirer-fans.de)
  • L'invention porte sur de nouveaux procédés à base d'hybridation de détection et quantification d'analytes d'acides nucléiques en phase soluble comprenant l'utilisation de nouveaux polymères de capture et/ou systèmes de signalisation. (toddbilleci.com)
  • Breast cancer is the most common tumor type and the leading cause of cancer-related death in women (Jemal et al. (justia.com)
  • The methods may be used, for example, to estimate the number of separate molecules of a given type or types within a sample. (patsnap.com)
  • Present provides two main operations to X clients: update a region of a window using part of or all the contents of a pixmap PresentPixmap and set the type of presentation events related to a certain window that the client wants to be notified about PresentSelectInput. (kaltner-autohandel.at)
  • This is my very first encounter with functional equation of this kind, and methods of series solution and differential equations are of not much help. (researchgate.net)
  • Aspectsof this invention were made with government support (DOE grant numberDE- FG02-02ER63453). (fullblog.com.ar)
  • All the related parameters are to the expressible infected studies either on the lower Mechanisms of Inorganic and Organometallic or on the longitudinal hazard as penalized in this Paper. (scoutconnection.com)
  • Two investigators reviewed studies for relevance and extracted study population, methods, and results data. (bvsalud.org)
  • Each book openaccess release 22 standard api tutorial of method incorporates a adsorption, the time-to-event membership of cell stage. (steirer-fans.de)
  • When using higher book french animation history use methods, such as % vat, research couple or detector sets a research, as the valuable enlevages will almost find with the linear Estimation. (drpulley.co.uk)
  • The invention is embodied in a system for diabetes management including a medical device (MD) and a consumer electronic device (CED). (patsnap.com)
  • In one embodiment of the invention, a method for a minimally invasive surgical system is disclosed. (patsnap.com)
  • Modern sequence comparison techniques overcome this objection by the use of multiple sequences. (wikipedia.org)
  • Compositions, methods and kits are disclosed for high-sensitivity single molecule digital counting by the stochastic labeling of a collection of identical molecules by attachment of a diverse set of labels. (patsnap.com)
  • To account an kilom of the Glucose invention of Jabir's buffer and to carry the intervention of its solvents, it is individual to anticipate it with what is to us of the special p in the hydrochloric ethnicity. (drpulley.co.uk)
  • The base sequences for the haplotypes are then compared. (wikipedia.org)
  • The difference between organisms is usually re-expressed as a percentage divergence, by dividing the number of substitutions by the number of base pairs analysed: the hope is that this measure will be independent of the location and length of the section of DNA that is sequenced. (wikipedia.org)
  • 2003 ). The NHGRI has categorized new sequencing approaches into those that offer near-term and revolutionary benefits with a 100-fold cost reduction per base pair (bp) within the next five years. (springer.com)
  • This understanding can also help answer questions related to morphology, ethics, medicine, and other pertinent fields of study. (asu.edu)
  • This application contains a Sequence Listing which was submitted in ASCII format and is incorporated by reference in its entirety. (justia.com)
  • Said ASCII copy is a copy of the sequence listing filed with International Application No. PCT/EP2014/051937, filed Jan. 31, 2014. (justia.com)
  • Therefore, concerning this industry, still existing does not need as procedure of processing loaded down with trivial details as the prior art and still can keep the demand of the electrode test piece of enough big current signal simultaneously.The present invention is exactly for solving this problem that has application. (google.com)
  • This technology relates to sound absorption material. (rpi.edu)
  • This technology relates to the decorrelation of audio signals for use in surround sound techniques. (rpi.edu)
  • This technology relates to solid-state devices as replacements for incandescent light bulbs. (rpi.edu)