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  • serum
  • Matsuura et al 5 reported that a serum protein, β2-glycoprotein I (β2-GP I) with high affinity for anionic phospholipid, is required for binding of aCLs to cardiolipin in autoimmune disease, whereas this requirement is not found in the binding that occurs in association with various infections. (bmj.com)
  • immune system
  • The Purdue Vaccination Studies and Auto-antibodies By Catherine O'Driscoll in Vaccine Articles and News A team at Purdue University School of Veterinary Medicine conducted several studies (1,2) to determine if vaccines can cause changes in the immune system of dogs that might lead to life-threatening immune-mediated diseases. (abovetopsecret.com)
  • specific
  • Neonatal lupus and congenital heart block are more common in newborns of mothers with SLE who carry specific antibodies referred to as anti-Ro (or anti-SSA) and anti-La (or anti-SSB). (livehopelupus.org)
  • types
  • HIV-1 infection and vaccination induce multiple types of antibodies, including antibodies to envelope variable loops, the CD4 binding site, and the chemokine receptor binding site. (sciencemag.org)
  • made
  • It is helpful for the newborn baby's doctor to be made aware if the mother is known to carry these antibodies, even prior to delivery. (livehopelupus.org)
  • levels
  • Decreased degradation was associated with manifestations of glomerulonephritis as well as low complement levels and elevated levels of antibodies directed against histones and DNA. (biomedcentral.com)
  • rare
  • The mAbs 2F5 and 4E10, two additional rare broadly reactive neutralizing mAbs (2G12 and IgG1b12) ( 11 - 13 ), and 31 common human mAbs to HIV-1 Env were tested for reactivity with cardiolipin ( 14 ) ( Table 1 ). (sciencemag.org)
  • human
  • The design of a human immunodeficiency virus-1 (HIV-1) immunogen that can induce broadly reactive neutralizing antibodies is a major goal of HIV-1 vaccine development. (sciencemag.org)
  • A major obstacle to generating a successful human immunodeficiency virus-1 (HIV-1) vaccine is the inability to induce broadly reactive neutralizing antibodies after immunization with HIV-1 envelope proteins (Env) ( 1 ). (sciencemag.org)
  • Microphotograph of a histologic section of human skin prepared for direct immunofluorescence using an anti-IgG antibody. (livehopelupus.org)