• Administer RECARBRIO 1.25 grams (imipenem 500 mg, cilastatin 500 mg, relebactam 250 mg) by intravenous (IV) infusion over 30 minutes every 6 hours in patients 18 years of age and older with creatinine clearance (CLcr) 90 mL/min or greater. (nih.gov)
  • RECARBRIO 1.25 grams for injection is supplied as sterile powder for constitution in a single-dose vial containing imipenem 500 mg (anhydrate equivalent), cilastatin 500 mg (free acid equivalent), and relebactam 250 mg (anhydrate equivalent). (nih.gov)
  • Seizures and Central Nervous System Adverse Reactions: CNS adverse reactions such as seizures have been reported with imipenem/cilastatin, a component of RECARBRIO. (nih.gov)
  • Unlike imipenem, it is stable to dehydropeptidase-1, so can be given without cilastatin. (wikipedia.org)
  • imipenem/cilastatin decreases effects of BCG intravesical live by pharmacodynamic antagonism. (medscape.com)
  • Imipenem and cilastatin injection is used to treat certain serious infections that are caused by bacteria, including endocarditis (infection of the heart lining and valves) and respiratory tract (including pneumonia), urinary tract, abdominal (stomach area), gynecological, blood, skin, bone, and joint infections. (anticancercure.com)
  • Antibiotics such as imipenem and cilastatin injection will not work for colds, flu, or other viral infections. (anticancercure.com)
  • Imipenem and cilastatin injection comes as a powder to be mixed with liquid to be injected intravenously (into a vein) or intramuscularly (into a muscle). (anticancercure.com)
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  • When imipenem and cilastatin is given intramuscularly, it is injected into the muscles of the buttocks or thigh once every 12 hours. (anticancercure.com)
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  • Use imipenem and cilastatin injection exactly as directed. (anticancercure.com)
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  • Ask your healthcare provider what to do if you have any problems injecting imipenem and cilastatin injection. (anticancercure.com)
  • You should begin to feel better during the first few days of treatment with imipenem and cilastatin injection. (anticancercure.com)
  • Use imipenem and cilastatin injection until you finish the prescription, even if you feel better. (anticancercure.com)
  • If you stop using imipenem and cilastatin injection too soon or if you skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. (anticancercure.com)
  • Imipenem and cilastatin injection is also sometimes used to treat patients who have fever and are at high risk for infection because they have a low number of white blood cells. (anticancercure.com)
  • or any of the ingredients in imipenem and cilastatin injection. (anticancercure.com)
  • Read user comments about the side effects, benefits, and effectiveness of imipenem-cilastatin intravenous. (webmd.com)
  • Imipenem is always given in combination with another drug cilastatin and sometimes also relebactam. (msdmanuals.com)
  • Antimicrobial susceptibility was performed by Modified Kirby-Baeur method with the organism tested against ceftazidime (30µg), cefotaxime (30µg), amoxicillin clavulinic acid (20/10µg), cefepime (30µg), ciprofloxacin (5µg), gentamicin (10µg), trimethoprim-sulphamethoxazole (23.75/1.25µg), imipenem (10µg) and doripenem (10µg) (Oxoid, UK). (bvsalud.org)
  • The EPK were resistant to ceftazidime (100%), cefotaxime (94.0%), trimethoprim-sulphamethoxazole (92.0%), gentamicin (70.0%) and ciprofloxacin (70.0%) but 100% susceptible to both doripenem and imipenem. (bvsalud.org)
  • 32% of antibiotics are dispensed without farmers were implemented, laboratory Typhoid fever 598 (11) 654(19) 51 (1) 25 (3) prescription ( Farah et al, 2014 ). (who.int)
  • Imipenem is in a class of medications called carbapenem antibiotics. (anticancercure.com)
  • The consequence of this situation is an excessive diagnosis of neonatal infection and the over-prescription of antibiotics. (scirp.org)
  • Your doctor may prescribe other prescription drugs and antibiotics to treat stomach ulcers. (plushcare.com)
  • Eligible studies were those analyzing original data on the prescription and use of antibiotics in outpatient or inpatient settings in Iran. (biomedcentral.com)
  • the strains showed different levels of resistance to antibiotics including, 42.8% to Tobramycin, 20% to Ceftazidime, and 2.8% to Imipenem. (scholarsresearchlibrary.com)
  • Regarding the high percentage of resistance of isolated Pseudomonas aeruginosa to the antibiotics of the ESBL, the accurate performance of antibiogram tests before the prescription of antibiotics seems to be an unavoidable necessity in the treatment of infections resulted from these bacteria. (scholarsresearchlibrary.com)
  • 1 Eight Asian countries reported frequencies found that 37% of the carbapenem prescriptions were of isolation of Pseudomonas spp. (who.int)
  • Ongoing antimicrobial susceptibility testing and antibiotic prescription surveillance are critical for enhancing antimicrobial stewardship measures. (japsonline.com)
  • We collected administrative, mortality, antibiotic prescription, and blood culture data for hemato-oncology patients. (datexis.com)
  • Carbapenems are the best antibiotic treatment option for infections arising from these organisms although a coordinated rational usage is desired along with functional antibiotic prescription policy to avoid treatment failures. (bvsalud.org)
  • Provider and patient drivers of ototopical antibiotic prescription variability. (medscape.com)
  • Antimicrobial susceptibility profile showed that the majority of the isolates were sensitive to Imipenem and Nitrofurantoin while most were significantly resistant to, augmentin, ampicillin, cotrimoxazole, gentamicin, cefuroxime, cefotaxime, and ceftazidime. (ispub.com)
  • The goal of this study was to characterize P. aeruginosa isolates and identify the prevalence rate of P. aeruginosa resistant to imipenem due to metallo-ßlactamase (MBL) genes. (japsonline.com)
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  • You may develop antibiotic resistance if you don't finish your amoxicillin prescription. (plushcare.com)
  • The MBL genes, bla IMP and bla VIM , were finally identified using the polymerase chain reaction (PCR) within imipenem-resistant strains. (japsonline.com)
  • PCR showed that eight strains of imipenem-resistant P. aeruginosa contained bla VIM , while bla IMP gene was not detected. (japsonline.com)
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  • The results of meta-analysis also showed that the antibiotic prescribing accounted for 45% of prescriptions in outpatient settings and 39.5%, 66%, and 75.3% of patients in all wards, pediatrics wards, and ICU wards of inpatient settings, respectively. (biomedcentral.com)
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