• Patients with missing platelet count data (n=3), re-transplantation (n=8), and incomplete postoperative laboratory values (n=6) were excluded from this study. (researchsquare.com)
  • However, most of previous studies focused on platelet posttransplant, and the effect of preoperative platelet count on liver transplantation recipients has not been fully investigated. (researchsquare.com)
  • The effect of preoperative anxiety level. (deu.edu.tr)
  • Thus, we aimed to evaluate the influence of preoperative platelet count on postoperative morbidity after liver transplantation. (researchsquare.com)
  • The aim was to evaluate influence of preoperative thrombogenic factors on incidence of transferred tissue thrombosis in patients undergoing microvascular surgery. (lww.com)
  • The role of platelets on the prognosis of patients with liver transplantation remains unclear. (researchsquare.com)
  • After the inverse probability of treatment weighting analysis, patients in the high platelet count group had significantly higher risk of portal vein complication (OR: 9.210, 95%CI: 1.907 to 44.498, p=0.006) and early allograft dysfunction (OR: 2.087, 95%CI: 1.131 to 3.853, p=0.019). (researchsquare.com)
  • 8, 9] Patients with severe liver disease for liver transplantation have compromised platelet count and function. (researchsquare.com)
  • Preoperative management is a dynamic process in which patients and physicians are interdependent. (medscape.com)
  • Conclusions The preoperative MPV values and propofol consumption at 30 min among patients with high preoperative anxiety scores were high. (deu.edu.tr)
  • to investigate the value of using preoperative neutrophil to lymphocyte and platelet to lymphocyte levels in the patients of borderline ovarian tumors. (biomedcentral.com)
  • The preoperative NLR-PLR was calculated as follows: patients with both elevated NLR (≥2.1) and PLR (≥120) were given a score of 2, and patients with only one or neither were given a score of 1 or 0, respectively. (biomedcentral.com)
  • The preoperative NLR-PLR score is a useful predictor of postoperative survival in the patients with stage I-II gastric cancer and may help identify high-risk patients for rational therapy and timely follow-up. (biomedcentral.com)
  • A study from our center found that an elevated preoperative GPS was superior to NLR and PLR for predicting prognosis of the patients with stage III gastric cancer [ 14 ]. (biomedcentral.com)
  • Therefore, a preoperative predictor of postoperative survival in the patients with stage I-II gastric cancer would be useful. (biomedcentral.com)
  • It has been shown that preoperative ADP-dependent platelet function could predict post-operative bleeding in cardiac surgery and guides waiting time in clopidogrel-treated patients (2,3). (isth.org)
  • Assessment of the correlation of preoperative PCS with platelet count and ADP-dependent platelet function and its association with postoperative blood loss in adult patients undergoing cardiac surgery. (isth.org)
  • Our objective was to observe the effects of extracorporeal circulation (ECC) with different time on platelet count in patients undergoing cardiac surgery. (nature.com)
  • However, there are few studies on the effects of ECC time on platelet count in patients after cardiac surgery, especially the effects of different ECC time on postoperative platelet count has not been reported. (nature.com)
  • The purpose of this study was to conduct a retrospective study to observe the effects of ECC with different time on platelet count in patients undergoing cardiac surgery, so as to provide reference for improving the prognosis of patients undergoing cardiac surgery. (nature.com)
  • Results: There was non significant increase in the reticulin level in bone marrow of any of the patients although platelet count was very highly significant (p-value 0.000) increased as regard day to day follow up after Romiplostim injection with maximum peak from day 15 till day 33 in most of the patients. (omicsonline.org)
  • No postoperative complications in relation to platelet count or bleeding tendency were recorded in patients except for one patient who did not respond by platelet count increase during the time schedule of the study and hence did not undergo surgical intervention. (omicsonline.org)
  • Comparison of Platelet-Rich Plasma Treatment and Partial Plantar Fasciotomy Surgery in Patients with Chronic Plantar Fasciitis: A Randomized, Prospective Study. (iasp-pain.org)
  • Platelet-Rich Plasma (PRP) injection has become a desirable alternative to Partial Plantar Fasciotomy (PPF) surgery and steroid injection for patients with chronic plantar fasciitis (CPF) due to its potential for shorter recovery times, reduced complications, and similar activity scores. (iasp-pain.org)
  • Hypercoagulation detected by fibrinogen/platelet ratio (FPR) ≥ 42 was found in 15/51 (29%) patients, mostly in high thrombotic risk group, 13 (52%) out of 25 had hypercoagulability. (lww.com)
  • Early preoperative identification of potentialy high-risk patients provides a possibility to modify surgical and anesthesiological management in order to improve surgical outcome. (lww.com)
  • To predict the regenerative rate of liver in patients with HCCs after right hepatectomy using texture analysis on preoperative CT combined with clinical features. (hindawi.com)
  • The use of texture analysis on preoperative CT combined with clinical features can be helpful in predicting the liver regeneration rate in patients with HCCs after right hepatectomy. (hindawi.com)
  • Anesthesiologists should know the comprehensive preoperative assessment and underlying pathophysiologic condition, determine an anesthesia plan for patients with HPS, meticulously account for HPS-related hypoxia and PVR conditions, and follow up closely perioperatively for successful outcomes. (transpopmed.org)
  • LT was contraindicated in previous years in ESLD patients with HPS due to potential preoperative and postoperative complications. (transpopmed.org)
  • Platelet and lymphocyte counts are routinely performed in most clinical laboratories worldwide, therefore we evaluated whether pretreatment PLR could predict the clinical outcome of PCa patients treated with ADT. (biomedcentral.com)
  • If the screening history raises the likelihood of defective hemostasis (liver disease, use of anticoagulant drugs or leukemia) a PT and APTT are indicated - a platelet count should be added for patients with leukemia. (clinlabnavigator.com)
  • For patients with a personal or family history of a bleeding disorder a full screening panel is recommended (PT, APTT, platelet count and bleeding time). (clinlabnavigator.com)
  • Several recent studies have shown no benefit in obtaining routine preoperative screening coagulation tests in patients with a negative clinical history related to hemostasis. (clinlabnavigator.com)
  • In one study of 750 preoperative patients, only 13 of 480 patients (2.7%) with a negative history had an abnormal PT or APTT, and in 12 of these 13 patients repeat testing was normal or surgery was uneventful without repeat testing. (clinlabnavigator.com)
  • In addition, a preoperative bleeding time may be warranted in patients with chronic renal failure, which is commonly associated with platelet dysfunction. (clinlabnavigator.com)
  • However, parathyroidectomy (PTx) is performed in patients with severe SHPT refractory to CH. This study investigated the effects of preoperative CH treatment on the operative course and pathological findings of resected parathyroid glands (PTGs) in patients undergoing PTx. (biomedcentral.com)
  • Accordingly, this study investigated whether preoperative CH treatment affects the pathological findings of resected PTGs and the PTx procedure in hemodialysis (HD) patients with refractory SHPT. (biomedcentral.com)
  • We performed a retrospective observational study to evaluate the effects of preoperative CH treatment on the pathological findings of resected hypertrophic PTGs and the intraoperative course in HD patients with refractory SHPT who had undergone PTx between April 2002 and March 2014. (biomedcentral.com)
  • Some patients may be on platelet inhibitors, including aspirin or clopidogrel, and it is unlikely that the surgeon would proceed with surgery while a patient is on these agents. (renalandurologynews.com)
  • No large-scale study has evaluated the clinical implications of preoperative ALI in patients with RCC yet. (biomedcentral.com)
  • Background: Preoperative bridging with a glycoprotein IIb/IIIa inhibitor is often performed in patients with prior coronary stents undergoing surgery who require antiplatelet therapy discontinuation, but its safety and efficacy have received limited study. (elsevierpure.com)
  • Methods: We conducted a weighted meta-analysis of preoperative bridging studies published between 2002 and 2013 in patients with coronary stents undergoing surgery. (elsevierpure.com)
  • Conclusions: Preoperative bridging with a glycoprotein IIb/IIIa inhibitor in patients undergoing surgery after coronary stenting does not abolish the risk of perioperative stent thrombosis and may carry increased risk for bleeding. (elsevierpure.com)
  • A total of 100 patients did not receive medication perioperatively, and 100 subsequent patients received preoperative DDAVP. (wikigenes.org)
  • Therefore, before any surgical procedure, the preoperative evaluation of these patients must include a complete blood count (CBC), PT, international normalized ratio (INR) and APTT 9 . (bvsalud.org)
  • L'objectif de notre étude est de décrire les caractéristiques hématologiques des patients atteints de COVID-19 hospitalisés au niveau du CHU d'Oran en Algérie. (bvsalud.org)
  • Patients et méthodes : Il s'agit d'une étude prospective menée entre le 1er Juillet et le 15 Octobre 2020 ayant inclus des patients hospitalisés et/ou suivis au niveau des unités COVID-19 du CHU Oran en Algérie. (bvsalud.org)
  • citation needed] Bleeding disorders: Individuals with the syndrome have platelet dysfunction. (wikipedia.org)
  • As preoperative inflammatory markers, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been suggested to be useful for discriminating malignant and benign ovarian tumors. (biomedcentral.com)
  • The preoperative neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are associated with poor prognosis of gastric cancer. (biomedcentral.com)
  • After multivariable regression analysis, high platelet count was independently associated with postoperative portal vein complication (odds ratio [OR]: 8.821, 95% confidence interval [CI]: 2.260 to 34.437). (researchsquare.com)
  • High preoperative platelet count could be an adverse prognostic predictor for liver transplantation recipients. (researchsquare.com)
  • Therefore, this retrospective study aimed to determine the relationship between preoperative platelet count and outcome after adult liver transplantation. (researchsquare.com)
  • However, other systemic inflammation-based prognostic scores, including the modified Glasgow prognostic score, the prognostic nutritional index, and the combination of platelet count and NLR, were not. (biomedcentral.com)
  • PCS estimated by the Quantra QPlus System is associated with platelet count and ADP-dependent platelet function (1). (isth.org)
  • PCS demonstrated a weak correlation with platelet count (r=0.42) and MA-ADP (r=0.46) and a negligible correlation with % ADP-inhibition (r=-0.21) and Verify Now PRU (r=0.29). (isth.org)
  • Primary outcome was the platelet count before operation (T 1 ), at the end of operation (T 2 ), on the first day (T 3 ), the second day (T 4 ) and the fifth day after operation (T 5 ). (nature.com)
  • Data on platelet count, blood loss and red blood cell (EC) transfusions during 48 h postoperatively were collected. (eur.nl)
  • Platelet count decreased by 28% after the pre-operative IA. (eur.nl)
  • The laboratory blood tests, including platelet count, protrombin time, activated partial tromboplastin time were normal. (ispub.com)
  • PLR was calculated as the ratio of platelet count to lymphocyte count. (biomedcentral.com)
  • The hemostatic tests available to screen for a wide variety of coagulation and platelet abnormalities include the PT, APTT, platelet count and bleeding time. (clinlabnavigator.com)
  • His preoperative corrected platelet count was within the normal range. (bvsalud.org)
  • Lumbar magnetic resonance imaging demonstrated an SSDH extending from L3 to L4 with a significantly decreased platelet count (30.0 × 109/L). The pain was gradually relieved after 2 weeks of conservative treatment, and no neurological deficit occurred during the 1-year follow-up. (bvsalud.org)
  • Postoperative evaluation of the platelet count (n=80). (cams.cn)
  • 0.001).Significant variation by sex was observed for the platelet count. (bvsalud.org)
  • Abstract PR043: Assessment of Preoperative Thrombogenic Risk. (lww.com)
  • Platelet to Lymphocyte ratio (PLR) is thought to be associated with a worse outcome in multiple types of cancer. (biomedcentral.com)
  • Similarly, platelet to lymphocyte ratio (PLR) is also a systemic inflammation-based parameter. (biomedcentral.com)
  • Conclusion : Certains paramètres tels que la lymphopénie et l'éosinopénie présentent une valeur diagnostique importante, alors que d'autres paramètres tels que le NLR (Neutrophils-to-lymphocytes ratio), le MLR (Monocyte -to-lymphocytes ratio) et le PLR (Platelet-to-lymphocytes ratio) offrent une valeur pronostique très précieuse. (bvsalud.org)
  • mean age 64 years) on platelet P2Y 12 -inhibitors undergoing cardiac surgery (38 CABG, 2 other). (isth.org)
  • To investigate whether the administration of renin-angiotensin system (RAS) inhibitors and statins could alleviate atrial fibrosis via platelet-derived growth factor (PDGF)/Rac1 /nuclear factor-kappa B (NF-κB) axis. (medsci.org)
  • [ 17 , 25 ] Conventional non-selective NSAIDs reversibly inhibit COX and interfere with platelet functions, while selective COX-2 inhibitors have less antiplatelet effects than conventional non-selective NSAIDs. (medscape.com)
  • [ 33 ] Selective COX-2 inhibitors may cause less bleeding than non-selective NSAID, because coxibs do not interfere the normal mechanisms of platelet aggregation and hemostasis, whereas non-selective NSAID produces significant reductions in platelet aggregation and serum thromboxane B 2 . (medscape.com)
  • Normal healthy women undergoing minor procedures may be seen by both the surgeon and the anesthesia personnel on the day of surgery in the preoperative holding area. (medscape.com)
  • 35%, preoperative cardiogenic shock, New York Heart Association (NYHA) ≥ III, history of preoperative administration of antiplatelet agents, presence of congenital heart disease, systemic glucocorticoid medication or perioperative glucocorticoid substitution, immunosuppressive medication, pregnancy, extracorporeal membrane oxygenation (ECMO), or preoperative intra-aortic balloon pump (IABP) initiation. (biomedcentral.com)
  • There has recently been a reevaluation of the need for preoperative testing of hemostasis, driven by a desire to reduce the expense of unnecessary laboratory tests that are of no clinical value. (clinlabnavigator.com)
  • There is no doubt that the most important part of a preoperative screen of hemostasis is a carefully documented clinical history. (clinlabnavigator.com)
  • Platelets can also be increased by the thrombocytosis induced by cancer. (biomedcentral.com)
  • Background: Preoperative thrombocytosis (PTC) is frequently observed in various solid malignancies and often associated with an unfavourable oncological outcome. (uni-muenchen.de)
  • Due to the absence of specific preoperative criteria for BOTs, diagnosis is often made by the pathological examinations of the surgical specimens. (biomedcentral.com)
  • The mechanism of Hermansky-Pudlak syndrome indicates that platelets in affected individuals accumulate abnormally with thrombin, epinephrine, and adenosine diphosphate, furthermore platelets in these individuals have a lower amount of dense bodies The diagnosis of HPS is established by clinical findings of hypopigmentation of the skin and hair, characteristic eye findings, and demonstration of absent dense bodies on whole mount electron microscopy of platelets. (wikipedia.org)
  • TEPs had robustness, compatibility, and universality for preoperative diagnosis of ovarian cancer since it withstood validations in populations of different ethnicities, heterogeneous histological subtypes, and early-stage ovarian cancer. (amsterdamumc.org)
  • Ready, get set, go: Fast preoperative genetic diagnosis is the present future in Lynch syndrome surgical strategy. (cdc.gov)
  • Experimental and clinical studies investigated the role of platelet in candidates for liver transplantation point toward a dualistic result. (researchsquare.com)
  • To the best of our knowledge, although NLR and PLR levels (as preoperative markers) have been the subject of many studies concerning ovarian cancers, no specific studies associated with BOTs were found. (biomedcentral.com)
  • With the extension of ECC time, the drop in platelet counts is more pronounced, the volume of perioperative blood loss and blood products transfusion are more, and the recovery level and speed of platelet counts is lower. (nature.com)
  • 11-13] Although platelet is indispensable for liver tissue repair after liver transplantation, platelet can also contribute to graft injury through ischemia/ reperfusion injury. (researchsquare.com)
  • The future remnant liver was semiautomatically segmented, and the volume of future remnant liver on preoperative CT (LV pre ) and the volume of remnant liver on following-up CT (LV fu ) were measured. (hindawi.com)
  • The activated partial thromboplastin time (APTT) reflects all clotting factors except platelet factor III and factors XIII and VII and is indicative of the function of the coagulation mechanism's intrinsic pathway. (bvsalud.org)
  • In addition, immune function is compromised by systemic inflammatory response (SIR) mediators which then increase the leukocytes, neutrophils, platelets, C reactive protein (CRP) and fibrinogen concentrations. (biomedcentral.com)
  • Data regarding age, menopausal status, preoperative ultrasound findings, ca125 and complete blood counts were reviewed. (biomedcentral.com)
  • In addition, other studies demonstrated that AngII activated platelet-derived growth factor-A (PDGF-A), a novel contributor to cardiac remodelling, to result in atrial fibrosis in pressure-overloaded mouse model [ 13 ] . (medsci.org)
  • The study evaluates the ability of osteoprogenitors treated with platelet-derived growth factor BB (PDGF-BB) delivered on vinyl styrene microbeads (VSM) to regenerate rat calvarial critical-size defects (CSDs). (allenpress.com)
  • Platelet-derived growth factor BB (PDGF-BB) is the most potent mitogenic and chemotactic member of PDGFs. (allenpress.com)
  • It is an analogous biologic agent constituting concentrated platelets, the primary component of which is believed to be products of degradation consisting of transforming growth factor (TGF), the insulin-like growth factor-1 (IGF-1), Platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF) [ 8 ]. (biomedcentral.com)
  • [ 26 , 27 ] In this study, perioperative administration of 400 mg of celecoxib had no significant effects on blood loss, thus confirming indirectly that celecoxib has little effect on serum thromboxane or platelet functions. (medscape.com)
  • There can be a relationship between increased platelet activity and anxiety and depression. (deu.edu.tr)
  • In their follow-up study, preoperative celecoxib 400 mg showed better morphine-sparing effects than a single 200 mg preoperative dose of celecoxib. (medscape.com)
  • The results of the present study suggest that preoperative CH treatment might introduce pathological changes in resected PTGs in PTx for severe SHPT, but it does not affect the operative time. (biomedcentral.com)
  • The platelet is a primary factor in various physiological and pathological processes. (researchsquare.com)
  • Psychological preparedness, including a mutidisciplinary approach to the preoperative preparation including primary care, physical therapy, neurosurgery, and anesthesiology, may allow the most informed and prepared patient. (renalandurologynews.com)
  • Preoperative CCB administration is associated with less incidence of MICS. (biomedcentral.com)
  • Exploratory outcome was the value of TEPs in public pan-cancer platelet transcriptome datasets. (amsterdamumc.org)
  • The association of preoperative PCS with postoperative blood loss is unknown. (isth.org)
  • ROC analysis: preoperative platelet function parameters and severe blood loss (>1000 mL at 24 hours). (isth.org)
  • Since platelets are necessary for blood clotting, individuals will bruise and bleed easily. (wikipedia.org)
  • This is a measure of red cells, white cells and platelets in your blood. (labtestsonline.org.uk)
  • The purpose of the preoperative evaluation is not to provide a general screening examination. (medscape.com)
  • In these circumstances, the balance of risk and benefit may favor immediate surgery even in the face of incomplete preoperative work-up. (renalandurologynews.com)
  • The extent of preoperative laboratory testing in each case depends entirely on the screening history (see Table). (clinlabnavigator.com)
  • The purpose of the preoperative workup is to assist the gynecologic surgeon in preparing their patient for surgery. (medscape.com)
  • Given the risk of corrective surgery and challenges inevitable to the cardiopulmonary and hematologic systems, rigorous preoperative preparation is warranted. (renalandurologynews.com)
  • The main aim of our initial approach was preoperative management of the anemia. (medscape.com)
  • Previous studies have shown that conventional preoperative non-selective NSAIDs increase bleeding risks. (medscape.com)
  • Conclusion: Higher BMI, higher platelet levels, and proctocolectomy were significant predictors of PMVT in multivariate analysis. (sages.org)
  • A thorough medical and surgical history and review of systems regarding significant medical conditions is an important start to the preoperative evaluation. (medscape.com)
  • Results There was a statistically significant difference between the groups in terms of preoperative MPV and demographic data, including age and sex. (deu.edu.tr)
  • Background The mean platelet volume (MPV) is an important indicator of platelet function with large platelets showing higher enzymatic and metabolic activity than other platelets. (deu.edu.tr)
  • Visual Analog Score (VAS) and Roles-Maudsley Scale (RM) were collected during the preoperative visit and 3, 6, and 12 months postoperatively. (iasp-pain.org)
  • Preoperative and postoperative visual analog scale (VAS), Boston carpal tunnel syndrome questionnaire-symptom severity scale (BCTQ-SSS), Boston carpal tunnel syndrome questionnaire-functional status scale (BCTQ-FSS), and grip strength were used to examine the patient's symptoms and function. (biomedcentral.com)
  • Platelet-rich plasma (PRP) has been utilized as a safe treatment form in divergent settings [ 7 ]. (biomedcentral.com)
  • Platelets are reprogrammed by cancer via a process called education, which favors cancer development. (amsterdamumc.org)
  • Yang D, Yuan J, Liu G, Ling Z, Zeng H, Chen Y, Zhang Y, She Q, Zhou X. Angiotensin Receptor Blockers and Statins Could Alleviate Atrial Fibrosis via Regulating Platelet-Derived Growth Factor/Rac1 /Nuclear Factor-Kappa B Axis. (medsci.org)
  • The preoperative regimen should be documented and detailed instructions to the patient should be given, specifically to avoid cessation of opioids to prevent immediate postoperative acute withdrawal, happening at the time of acute increase in pain. (renalandurologynews.com)
  • [ 2 ] Many medical conditions can change or occur within a few weeks, days, or hours after the preoperative evaluation. (medscape.com)