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  • seizures
  • Pregnenolone is used to strengthen the heart and treat arthritis, prostate issues, allergic reactions, seizures and depression, explains WebMD. (reference.com)
  • found
  • Pregnenolone has been found to bind with high, nanomolar affinity to microtubule-associated protein 2 (MAP2) in the brain. (wikipedia.org)
  • Pregnenolone was found to induce tubule polymerization in neuronal cultures and to increase neurite growth in PC12 cells treated with nerve growth factor . (wikipedia.org)
  • Research into pregnenolone benefits can be traced back to the 1940's, when it was found to aid the productivity of factory workers, whilst helping to reduce stress . (antiaging-systems.com)
  • It prevents CB1 receptor agonists like tetrahydrocannabinol, the main active constituent in cannabis, from fully activating the CB1 Pregnenolone has been found to bind with high, nanomolar affinity to microtubule-associated protein 2 (MAP2) in the brain. (wikipedia.org)
  • decrease
  • According to the Langone Medical Center at New York University, pregnenolone may also decrease the effectiveness of benzodiazepine drugs, such as Xanax and Valium. (livestrong.com)
  • brain
  • Pregnenolone can effect brain function in a very specific way. (roperandparry.com.au)
  • Cognitex® with Pregnenolone & Brain Shield™ by Life Extension was recommended by. (pureformulas.com)
  • I have only been taking this Cognitex® with Pregnenolone & Brain Shield™ by Life Extension for two weeks. (pureformulas.com)
  • Cognitex® with Pregnenolone & Brain Shield™ Softgels from Life Extension® may guard your brain cells against oxidative stress and age-related conditions. (pureformulas.com)
  • Take Cognitex® with Pregnenolone & Brain Shield™ - 90 Softgels from Life Extension® daily and it could potentially enhance memory and support healthy brain function. (pureformulas.com)
  • The 3β-methyl ether of pregnenolone, 3β-methoxypregnenolone (MAP-4343), retains similar activity to pregnenolone in regards to interaction with MAP2, and is under development for potential clinical use for indications such as the treatment of brain and spinal cord injury and depressive disorders. (wikipedia.org)
  • levels
  • It has also been suggested that Pregnenolone may support a healthy immune system, short term and long term memory, low stress levels, energy, and restful sleep. (bodybuilding.com)
  • It is believed that decreased levels of pregnenolone with aging prevents our ability to think fast and retrieve stored information. (roperandparry.com.au)
  • Anecdote indicates that pregnenolone helps improve energy levels, helps to combat stress, and helps to improve sleep length and quality. (bodybuilding.com)
  • clinical
  • As of January 2015, research on pregnenolone is ongoing and the health benefits have not been proven in professional clinical studies, according to the American Cancer Society. (reference.com)
  • effects
  • High doses of pregnenolone can have harmful side effects, such as irritability, insomnia, acne, aggressiveness and facial hair growth on women, notes WebMD. (reference.com)