• In addition to expression in the endometrium, bovine uterine serpin is also expressed in the ovary (follicles, corpus luteum, and cumulus-oocyte complex) and by cotyledons of the placenta. (wikipedia.org)
  • Ovaries from abattoirs are grouped into four categories: ovaries without corpus luteum and dominant follicles (-CL and -FD), without corpus luteum and with dominant follicles (-CL and + FD), with corpus luteum and without dominant follicle (+ CL and -FD), and with corpus luteum and dominant follicles (+ CL and + FD). (ifory.id)
  • Certain fetal and maternal conditions have been shown to have environmental and genetic components. (medscape.com)
  • It is hypothesized that NLR family participates in maternal splenic immune regulation during early pregnancy in sheep. (animal-reproduction.org)
  • In this study, maternal spleens were collected on day 16 of the estrous cycle, and days 13, 16 and 25 of gestation (n = 6 for each group) in ewes. (animal-reproduction.org)
  • In addition, expression values of NAIP and NLRP7 mRNA and proteins were improved at days 16 and 25 of pregnancy, and NLRP1 was peaked at days 13 and 16 of pregnancy in the maternal spleen. (animal-reproduction.org)
  • In summary, early pregnancy changes expression of NLR family in the maternal spleen, which may be related with the maternal splenic immunomodulation during early pregnancy in sheep. (animal-reproduction.org)
  • Pattern recognition at the maternal-fetal interface. (animal-reproduction.org)
  • Contrast-enhanced ultrasonography of maternal and fetal blood flows in pregnant bitches [4] "We evaluated the potential usefulness of CEUS to assess fetal-maternal circulation during pregnancy in dogs. (edu.au)
  • The effect of melatonin on the secretion of progesterone in sheep and on the development of ovine embryos in vitro. (veterinarskiglasnik.rs)
  • Reproductive risk of toxicant exposure includes fetal effects, especially congenital anomalies. (medscape.com)
  • The authors present the importance of the melatonin protein hormone by focusing on the reproductive processes in domestic sheep. (veterinarskiglasnik.rs)
  • Nutrition is one of the most important environmental factors affecting reproductive performance in sheep. (biomedcentral.com)
  • Recently, transcriptomic analyses via RNA-seq and microarray analysis of different sheep reproductive organs have provided further insights into the gene expression landscapes of these tissues, and a few novel genes (e.g. (biomedcentral.com)
  • These proteins appear to be inactive protease inhibitors and may function during pregnancy to regulate immune function or participate in transplacental transport. (wikipedia.org)
  • Late in pregnancy, uterine serpin protein can be found in the lumenal epithelium as well, perhaps as glandular epithelial cells move to the uterine lumen. (wikipedia.org)
  • This protease activity has recently been ascribed to serine metalloprotease(s), including pregnancy-associated plasma protein-A (PAPP-A), which was first detected in human follicular fluid nearly 20 yr ago. (bioone.org)
  • Normally performed during the second trimester of a pregnancy, this invasive procedure allows the detection of health problems in the fetus as early as fifteen weeks gestation. (asu.edu)
  • Cao N, Cao L, Gao M, Wang H, Zhang L, Yang L. Changes in mRNA and protein levels of gonadotropin releasing hormone and receptor in ovine thymus, lymph node, spleen, and liver during early pregnancy. (animal-reproduction.org)
  • Feng P, Wu J, Ren Y, Zhang L, Cao J, Yang L. Early pregnancy regulates the expression of prolactin and its receptor in the thymus, the liver, the spleen and lymph nodes in sheep. (animal-reproduction.org)
  • Your dietary needs during pregnancy are different, with greater needs for protein (80-100 grams per day is recommended), greater needs for sodium, and a propensity to low blood sugar. (anneshealthplace.com)
  • Conceptus-endometrial interactions in ruminants are complex and involve carefully orchestrated temporal and spatial alterations in gene expression regulated by hormones from the ovary and conceptus. (bioscientifica.com)
  • To improve our knowledge of the sheep prolificacy traits, we conducted mRNA-miRNA integrated profiling of ovarian tissues from two pure breeds with large (Finnsheep) vs. small (Texel) litter sizes and their F1 crosses, half of which were fed a flushing diet. (biomedcentral.com)
  • Prenatal testosterone (T) excess from days 30-90 of gestation disrupts gonadotropin surge and ovarian follicular dynamics and induces insulin resistance and functional hyperandrogenism in sheep. (biomedcentral.com)
  • This review summarizes evidence for the role of proteolytic enzymes that degrade and inactivate insulin-like growth factor binding proteins (IGFBP) during follicular development in mammals. (bioone.org)
  • In sheep, prenatal T excess from days 30 to 90 of gestation (T30-90) enhances follicular recruitment and persistence [ 13 ] and causes disruptions in several key mediators of folliculogenesis [ 15 - 18 ]. (biomedcentral.com)
  • In particular, sheep uterine serpin can inhibit lymphocyte and natural killer cell function in vitro and reduce natural-killer cell mediated abortion in a mouse model. (wikipedia.org)
  • Oocytes were collected from slaughterhouse-derived ovaries, matured in vitro, and injected with frozen-thawed stallion sperm. (bioone.org)
  • Uterine serpins are members of the A clade of the serine protease inhibitor (serpin) superfamily of proteins and are encoded by the SERPINA14 gene. (wikipedia.org)
  • Uterine serpins were originally described in the uterine secretions of unilaterally-pregnant sheep as a pair of 57 kDa and 55 kDa glycoproteins. (wikipedia.org)
  • Termed uterine milk proteins, their identification as members of the serpin superfamily was based on sequencing of the cDNA for the sheep gene. (wikipedia.org)
  • The pig uterine serpin was first identified because of its association with an iron-binding uterine protein termed uteroferrin. (wikipedia.org)
  • Among the clades in which uterine serpin genes exist are the Cetartiodactyla (dolphin, cow, water buffalo, sheep, goat, pig), Perissodactyla (horse) and some carnivores (dog, giant panda) The uterine serpin gene is not expressed in all carnivores since the only uterine serpin identified in the cat is a pseudogene. (wikipedia.org)
  • Uterine serpins from the sheep and pig are not inhibitory towards a variety of proteases. (wikipedia.org)
  • Two important fertility traits, the ovulation rate and litter size, are of high economic value in sheep [ 1 ]. (biomedcentral.com)
  • The average canine gestation period from ovulation to birth (parturition) is approximately 64 days and there have been identified about 400 congenital disorders relating to dog development. (edu.au)
  • The highly prolific breeds of domestic sheep ( Ovis aries ) are globally valuable genetic resources for sheep industry. (biomedcentral.com)
  • In domestic sheep ( Ovis aries ), a large range of litter sizes (number of offspring from 1 to 9) has been observed among and within breeds, in contrast to several other domestic animal species in which females generally have either 1-2 (cattle, horses and goats) or more than 3 offspring (e.g., dogs and pigs). (biomedcentral.com)
  • The critical effects of acute duration iodomethane exposure are: (1) fetal losses in rabbits, (2) lesions in rat nasal epithelium, and (3) transient neurotoxicity in rats. (cdc.gov)
  • Uteroferrin is transferred across the placenta where it gives up its iron to fetal transferrin. (wikipedia.org)
  • Their placenta lactogen production seems to be well established for the sheep, and Atkinson et al. (ucsd.edu)
  • Expression of NLR family, including NOD1, NOD2, class II transactivator (CIITA), NLR family apoptosis inhibitory protein (NAIP), nucleotide-binding oligomerization domain, Leucine rich repeat and Pyrin domain containing 1 (NLRP1), NLRP3 and NLRP7, was analyzed using quantitative real-time PCR, Western blot and immunohistochemistry analysis. (animal-reproduction.org)
  • Abadía-Molina F, Morón-Calvente V, Baird SD, Shamim F, Martín F, MacKenzie A. Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division. (animal-reproduction.org)
  • Diez E, Yaraghi Z, MacKenzie A, Gros P. The neuronal apoptosis inhibitory protein (Naip) is expressed in macrophages and is modulated after phagocytosis and during intracellular infection with Legionella pneumophila . (animal-reproduction.org)
  • The identification and characterization of differentially expressed genes and miRNAs in the ovaries of sheep provided insights into genetic and environmental factors affecting prolificacy traits. (biomedcentral.com)
  • Earlier studies have indicated that fertility traits in sheep can be regulated by individual genetic markers with major effects, which are known as fecundity genes [ 10 , 11 ], or by polygenic effects, particularly in prolific breeds, such as Finnsheep and Romanov [ 12 ]. (biomedcentral.com)
  • [email protected] Appl Biochem Biotechnol (2013) 169:1727-1751 enzymes- superoxide dismutase, catalase, and glutathione peroxidase-were determined inthe liver, kidney and ovary. (nomedicalcare.com)
  • With well over 5 million U.S. women affected, women with polycystic ovary syndrome (PCOS) are frequent patients in infertility clinics, seeking assistance in becoming pregnant [ 1 ]. (biomedcentral.com)
  • Equatorial segment protein (ESP), a novel 349-amino acid concanavalin-A-binding protein encoded by a two-exon gene ( SP-ESP ) located on chromosome 15 at q22, has been localized to the equatorial segment of ejaculated human sperm. (bioone.org)
  • The purpose of obstetrics is to maintain the health of the pregnant woman and to ensure optimal health of the fetus. (medscape.com)
  • In sheep as a seasonal breeder and short-day animal species, seasonal increases in melatonin production stimulate sexual activity. (veterinarskiglasnik.rs)
  • T treatment from days 60-90 of gestation produces a milder phenotype, albeit with reduced fecundity. (biomedcentral.com)
  • A milder PCOS-like phenotype with reduced fecundity was found in sheep treated prenatally from days 60-90 of gestation (T60-90), where only 40 % of such prenatal T-treated females became pregnant [ 19 ]. (biomedcentral.com)
  • Nine bitches were examined at 23, 30, and 45 days of gestation using an ultrasound machine (LOGIQ E9) and SonoVue® contrast media as echo-signal enhancer. (edu.au)
  • Whether the hormonal control of PAPP-A production/activity by the ovary differs between monotocous and polytocous animals will require further study. (bioone.org)
  • 1993) suggested the production of a family of proteins by binucleate cells. (ucsd.edu)
  • The authors describe innovative possibilities for regulating melatonin levels in sheep production. (veterinarskiglasnik.rs)
  • Ethically, it's very difficult to study pregnant women. (anneshealthplace.com)
  • In the meantime, countless pregnant women are suffering with adrenal fatigue and even full-blown Addison's disease. (anneshealthplace.com)
  • The fact is, we just don't know much about how to help pregnant women with adrenal fatigue. (anneshealthplace.com)
  • The use of radiation for diagnostic imaging in the pregnant woman is usually associated with a high level of anxiety for the woman, her family, and, often, the physician. (medscape.com)
  • The birth and adult development of 'Dolly' the sheep, the first mammal produced by the transfer of a terminally differentiated cell nucleus into an egg, provided unequivocal evidence of nuclear equivalence among somatic cells. (bioscientifica.com)
  • My advice is to always have some good-quality carbohydrates with your protein, to eat plenty of good fats, to salt your food to taste, to drink lots of water (divide your weight in half and drink that many ounces per day), and to avoid simple sugar as much as possible. (anneshealthplace.com)