Loading...
  • placental
  • The value of serum human placental lactogen and Schwangerschaftsprotein 1 to determine gestation in an ante-natal population. (biomedsearch.com)
  • Single assays of Schwangerschaftsprotein 1 (SP1) and serum human placental lactogen (HPL) were performed in 500 consecutive patients attending a routine ante-natal clinic for their first visit. (biomedsearch.com)
  • human
  • The complete isolation of certain glycoproteins, later classified as pregnancy-specific, within human blood serum occurred in the early 1980s, when experimental techniques like molecular cloning became common practice. (wikipedia.org)
  • Human chorionic gonadotropin is glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5 αhCG and 22.2kDa βhCG. (wikipedia.org)
  • Human chorionic gonadotropin interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. (wikipedia.org)
  • Its structure is similar to that of the other glycoprotein hormones, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). (wikipedia.org)
  • The protein dimer contains 2 glycopeptidic subunits, labeled alpha and beta subunits, that are non-covalently associated (i.e., without any disulfide bridge linking them): The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids in human but 96 amino acids in almost all other vertebrate species (glycoprotein hormones do not exist in invertebrates). (wikipedia.org)
  • If pregnancy occurs, LH levels will decrease, and luteal function will instead be maintained by the action of hCG (human chorionic gonadotropin), a hormone very similar to LH but secreted from the new placenta. (wikipedia.org)
  • The PTGER3 gene is located on human chromosome 1 at position p31.1 (i.e. 1p31.1), contains 10 exons, and codes for a G protein coupled receptor (GPCR) of the rhodopsin-like receptor family, Subfamily A14 (see rhodopsin-like receptors#Subfamily A14). (wikipedia.org)
  • promoter
  • The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. (wikipedia.org)
  • Expression
  • We describe the increased expression of a specific member of the pregnancy specific glycoprotein family and show that induction of this gene is a very early event that does not appear to be dependent on activation of β-catenin. (biomedcentral.com)
  • An increased plasma transferrin level is often seen in patients suffering from iron deficiency anemia, during pregnancy, and with the use of oral contraceptives, reflecting an increase in transferrin protein expression. (wikipedia.org)
  • Also, PLP influences expression of glycoprotein IIb by interacting with various transcription factors. (wikipedia.org)
  • alpha subunit
  • It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and β (beta) subunit that is unique to hCG. (wikipedia.org)
  • confers
  • LH has a beta subunit of 120 amino acids (LHB) that confers its specific biologic action and is responsible for the specificity of the interaction with the LH receptor. (wikipedia.org)
  • vial
  • This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. (creativebiomart.net)
  • Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). (creativebiomart.net)
  • The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). (creativebiomart.net)
  • cell
  • The combined agents resulted in significantly increased E-cadherin levels in SW480 cells, and beta-catenin levels in both cell lines (assessed by in-cell westerns). (biomedsearch.com)
  • reactions
  • Allergies are hypersensitivity reactions of the immune system to specific substances called allergens (such as pollen, stings, drugs, or food) that, in most people, result in no symptoms. (wikipedia.org)
  • maintenance
  • CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. (wikipedia.org)
  • infection
  • These tests are more specific for syphilis than non-treponemal tests and, in the presence of a positive test, more likely indicate active infection. (wikipedia.org)