• Pregnancy management for diabetics needs stringent blood glucose control even in advance of having pregnancy. (wikipedia.org)
  • During a normal pregnancy, many physiological changes occur such as increased hormonal secretions that regulate blood glucose levels, such as a glucose-'drain' to the fetus, slowed emptying of the stomach, increased excretion of glucose by the kidneys and resistance of cells to insulin. (wikipedia.org)
  • 1989: George King, M.D., and colleagues demonstrate that high blood glucose levels activate protein kinase C (PKC), part of a major signaling pathway that causes cellular changes in the eye, kidney and arteries that lead to diabetic complications. (wikipedia.org)
  • She began her pioneering research on pregnancy in the late 1930s and soon showed the importance of strict blood glucose control and early delivery in ensuring the healthy delivery of newborns. (wikipedia.org)
  • Although there were two meta-analyzes that examined the association between health care and adverse pregnancy outcomes, their results were limited because they only included congenital anomaly and perinatal mortality, and they did not clarify the detailed situations of diabetes and health care. (springer.com)
  • Nutrition and weight management before and during pregnancy has a profound effect on the development of infants. (wikipedia.org)
  • He devoted his professional life to the care of diabetic patients and is remembered as the founder of the British Diabetic Association. (wikipedia.org)
  • Alfasigma USA, Inc. produces medical foods for people with diabetic peripheral neuropathy, early memory loss/Alzheimer's, high-risk pregnancy, depression, and other medical conditions. (wikipedia.org)
  • RESULTS A1C levels were significantly increased in late pregnancy, whereas serum glycated albumin showed no significant changes. (diabetesjournals.org)
  • Glycated albumin/A1C ratio, mean corpuscular hemoglobin, serum transferrin saturation, and serum ferritin were significantly decreased in late pregnancy. (diabetesjournals.org)
  • He is known for his hypothesis concerning the correlation of hyperglycemia during pregnancy and disease in later life. (wikipedia.org)
  • Miscarriage, also known as spontaneous abortion and pregnancy loss, is the natural death of an embryo or fetus before it is able to survive independently. (wikipedia.org)
  • Miscarriage is the most common complication of early pregnancy. (wikipedia.org)
  • Bleeding can be a symptom of miscarriage, but many women also have bleeding in early pregnancy and don't miscarry. (wikipedia.org)
  • Bleeding during pregnancy may be referred to as a threatened miscarriage. (wikipedia.org)
  • A chemical pregnancy refers to a pregnancy that was detected by testing but ends in miscarriage before or around the time of the next expected period. (wikipedia.org)
  • How many people are affected by or at risk for pregnancy loss or miscarriage? (wikipedia.org)
  • with these defects, and many other affected pregnancies end in miscarriage and stillbirth. (wikipedia.org)
  • Genetic counseling and genetic testing, such as amniocentesis, is usually offered during a pregnancy if holoprosencephaly is detected. (wikipedia.org)
  • Since pregnancy places a heavy strain on the kidneys , it is imperative that the kidneys be in good shape. (diabeticlive.com)
  • Omental adipose biopsies were collected in term pregnancy from women with normal glucose tolerance (NGT, n = 10) and GDM (n = 10). (ovid.com)
  • OGTT=oral glucose tolerance test Chapter 9: The Diabetic Foot/Wound Care. (e3mproject.eu)
  • This classification was widely adopted and allowed doctors to partially predict the course of a woman with diabetes during pregnancy and the chances of newborn survival. (wikipedia.org)
  • He wrote profusely on his subject and his books The Diabetic Life and The Diabetic ABC did much to simplify treatment for doctors and patients. (wikipedia.org)
  • Remote sites across the United States can now access Joslin's expertise in diabetic eye disease diagnosis and treatment. (wikipedia.org)