Loading...
  • genes
  • Diurnally regulated genes in the prefrontal cortex may be controlled by the circadian system, by sleep:wake states, or by cellular metabolism or environmental responses. (umd.edu)
  • parietal cortex
  • The results of this study are comparable with the conclusions of the previous meta-analysis of working memory mechanisms in children, which was carried out by Marie Arsalidou together with HSE researcher Zachary Yaple: during n-back task performance, not only prefrontal and parietal cortex regions are activated in children, but also other brain areas. (news-medical.net)
  • medial
  • The medial prefrontal cortex (mPFC), including the anterior cingulate subregion, has been implicated in contextual encoding, yet the nature of contextual representations formed by the mPFC is unclear. (pnas.org)
  • The medial prefrontal cortex (mPFC) is involved in various forms of cognition that depend on spatial and contextual information, including context-based cognitive tasks ( 2 ⇓ - 4 ), contextual fear conditioning ( 5 ), and context-induced drug relapse ( 6 ⇓ - 8 ), and is believed to be an important node in the "context" network ( 1 , 9 ⇓ ⇓ - 12 ). (pnas.org)
  • The most general conclusion we can reach is that the prefrontal cortex is extremely plastic and that the medial and orbital prefrontal regions frequently respond very differently to the same experience in the same brain and the rules that govern prefrontal plasticity appear to differ for those of other cortical regions. (uleth.ca)
  • Based on our previous finding that inactivation of the medial prefrontal cortex (mPFC) profoundly impairs rat's ability to discriminate time intervals, we investigated how the mPFC processes temporal information by examining activity of mPFC neurons in rats performing a temporal bisection task. (jneurosci.org)
  • In virtually all medial prefrontal and most orbitofrontal areas, increased expression of Mkp1 was observed after 10 days of cocaine taking, whereas after 60 days, enhanced expression was restricted to caudal parts of medial prefrontal and caudomedial parts of orbitofrontal cortex. (springer.com)
  • neurons
  • We found that rhesus monkeys can control the activity of neurons within the frontal eye field (FEF), an oculomotor area of the prefrontal cortex. (sciencemag.org)
  • To address this question, we examined the consequences of voluntary control of neurons in the frontal eye field (FEF), a visuomotor area within the prefrontal cortex with a known role in the programming of saccadic eye movements ( 9 ) and visual spatial attention ( 10 ), in rhesus monkeys ( Fig. 1A ). (sciencemag.org)
  • dorsal
  • We hypothesized that neuronal activity in striatum would increase in its dorsal part and that activity in frontal cortex would decrease with prolonged cocaine self-administration experience. (springer.com)
  • occurs
  • It is generally accepted that synaptic pruning in the cerebral cortex, including prefrontal areas, occurs at puberty and is completed during early adolescence [Huttenlocher PR, et al. (pnas.org)
  • It is thought that the reduced ability to recall the context of memories that occurs with advancing age, is evidence that the prefrontal cortex is also critical for context processing - a process involved in many cognitive functions. (memory-key.com)
  • basal
  • We demonstrate the performance of our model on two paradigmatic tasks used to investigate prefrontal and basal ganglia function. (frontiersin.org)
  • brain
  • The prefrontal cortex is a part of the brain located at the front of the frontal lobe. (goodtherapy.org)
  • The brain develops in a back to front pattern, and the prefrontal cortex is the last portion of the brain to fully develop. (goodtherapy.org)
  • The prefrontal cortex plays a key role in complicated intellectual processes, including the coordination of different brain areas that are activated during the use of working memory. (news-medical.net)
  • We review the plastic changes of the prefrontal cortex of the rat in response to a wide range of experiences including sensory and motor experience, gonadal hormones, psychoactive drugs, learning tasks, stress, social experience, metaplastic experiences, and brain injury. (uleth.ca)
  • function
  • An excellent example demonstrating the significance of the ventromedial prefrontal cortex's function is in the case of Phineas Gage, a railroad foreman who sustained an explosion-propelled rod through his brain's VmPC and survived. (wisegeek.com)
  • effects
  • 12. Age-dependent effects of lesioning the mesocortical dopamine system upon prefrontal cortex morphometry and PFC-related behaviours (A. Kalsbeek, J.P.C. de Bruin, M.G.P. Feenstra and H.B.M. Uylings). (elsevier.com)
  • evidence
  • 5. The anatomical relationship of the prefrontal cortex with the striatopallidal system, the thalamus and the amygdala: evidence for a parallel organization (H.J. Groenewegen, H.W. Berendse, J.G. Wolters and A.H.M. Lohman). (elsevier.com)