• The present disclosure relates to implantable, mechanically expandable prosthetic devices, such as prosthetic heart valves, and to methods and delivery assemblies for, and including, such prosthetic devices. (justia.com)
  • In preferred embodiments, the implantable medical device comprises an implantable luminal prosthesis, such as vascular and non-vascular stents and stents grafts. (patsnap.com)
  • There are a number of known repair devices (e.g., stents) and artificial valves, as well as a number of known methods of implanting these devices and valves in humans. (justia.com)
  • The results showed that this original valve exhibited the best haemodynamic performance, at rest and during exercise, when compared with the reported results of all other artificial valves in existence. (wikipedia.org)
  • The experimental and in vitro testing of this novel device took place in 1970, and in March 1971, Ionescu began, for the first time, the implantation of the pericardial valve in all three cardiac positions in humans. (wikipedia.org)
  • He created this artificial bioprosthetic heart valve as a three-cusp structure made of chemically treated bovine pericardium attached to a Dacron cloth-covered titanium frame. (wikipedia.org)
  • entitled "Supported Bioprosthetic Heart Valve with Compliant Orifice Ring," and in U.S. Pat. (justia.com)
  • The experimental and in vitro testing of this novel device took place in 1970, and in March 1971, Ionescu began, for the first time, the implantation of the pericardial valve in all three cardiac positions in humans. (wikipedia.org)
  • This invention relates generally to the field of implantable valvular prostheses, and more particularly to a holding mechanism used for implantation of valvular prostheses. (justia.com)
  • To facilitate the implantation of heart valve prostheses, various types of specialized holders have been developed. (justia.com)
  • Between 1971 and 1976 the valves had been made in Ionescu's own hospital laboratory. (wikipedia.org)
  • Approximately 200,000 pericardial valves manufactured by Shiley Laboratories were distributed around the world between 1976 and 1987 and it is presumed that most of them were implanted in patients. (wikipedia.org)
  • The sewing rim was bolstered for better and safer attachment to the heart annuli and its shape was anatomically contoured into two different configurations to better fit in the aortic and the atrio-ventricular positions. (wikipedia.org)
  • The geometry of the valve was slightly modified due to changes in the shape of the stent and by removing the outside pledgets around the posts. (wikipedia.org)
  • Among the known bioprosthetic valves, there are those which have a semi-rigid or relatively flexible frame or stent with (typically) three leaflets attached thereto, and those which have no stent. (justia.com)
  • The stent in a stented replacement heart valve typically defines a substantially circular base of the valve body, around which an annular suture ring is disposed for suturing the valve to surrounding tissue, and further comprises commissure posts defining the juncture between adjacent leaflets. (justia.com)
  • The entire Delrin structure was covered with seamless Dacron velour and at a later stage, the margins of the scalloped edges were covered with a thin layer of pericardium in an attempt to prevent or reduce the abrasion of the leaflets when in contact with this margin during valve closure. (wikipedia.org)
  • Prosthetic heart valves, at least those which include valve leaflets, can be generally categorized into one of two basic classes of replacement heart valves. (justia.com)
  • The first class includes heart valves which have one or more relatively rigid leaflets formed of a stiff biocompatible material. (justia.com)
  • The second class includes what will be referred to in this disclosure as bioprosthetic valves, which have flexible leaflets, typically made of a biological material. (justia.com)
  • It is flexible and shock absorbent, essential qualities for a tissue heart valve support. (wikipedia.org)
  • One should however keep in mind that any single investigator should resist the temptation to write a review of such a complex matter as tissue heart valves, and to cover the subject completely and fairly. (wikipedia.org)
  • When the commissure posts of the valve are coupled to the fingers, inward movement of the fingers causes the commissure posts to be deflected inward with respect to the valve, improving the implanting surgeon's access to the valve's suture ring and surrounding tissue. (justia.com)
  • Two other additions were made: an integral valve holder which prevents the touching of the valve's cusps, and a 'freeze-watch' indicator as a safe-guard against exposing the valves during transportation or storage at temperatures below 4 degrees Celsius. (wikipedia.org)
  • A holder for a prosthetic heart valve is disclosed. (justia.com)
  • The holder, comprising a holder assembly disposed at the distal end of an elongate handle, includes a plurality of distally-projecting fingers adapted to engage the commissure posts of a stented prosthetic valve. (justia.com)
  • entitled "Disposable Holder for Prosthetic Heart Valve," in U.S. Pat. (justia.com)
  • entitled "Prosthetic Valve Holder," in U.S. Pat. (justia.com)
  • The pericardial heart valve was invented by Marian Ionescu, a British surgeon working at the General Infirmary in Leeds, England. (wikipedia.org)
  • Such holders are intended to enable the implanting surgeon to precisely position the heart valve and suture ring either within the heart passageway or adjacent/above the aortic root of the patient and to securely hold the valve assembly in place until suturing is complete and the sutures are tied Off. (justia.com)
  • Sometimes the patient does not know what exactly is placed in his orbit csgo cheats download enucleation vac ban in one of our cases in which the patient removed the removable eye ball prosthesis before MRI but there was still some part of it in the orbit Figure. (theherdandherb.co.uk)