• Over the past 50 years, assessment of trauma patients has evolved because of an improved understanding of the distribution of mortality and the mechanisms that contribute to morbidity and mortality in trauma. (medscape.com)
  • Multiple retrospective and observational studies suggest that transfusion of older RBCs, particularly in trauma patients, is associated with increased morbidity including multiple organ failure and nosocomial infection [ 1 - 6 ]. (hindawi.com)
  • In view of the minimal analysis of this topic in the literature, this study was undertaken to analyse the incidence, patient characteristics, causes, morbidity and mortality associated with the management of small bowel perforations in a rural setting. (ispub.com)
  • Most studies documenting beneficial outcomes after AFB have been limited to mortality and morbidity rates, costs and length of hospital stay (LOS). (biomedcentral.com)
  • Sepsis is a leading cause of death in the US and worldwide, and represents a major cause of morbidity and mortality, for which there is no effective cure. (grantome.com)
  • When human illness results from an unintentional or intentional release of a toxin (chemicals produced by metabolism in an organism [e.g., ricin]) or a toxicant (natural or synthetic chemicals not metabolically produced by an organism [e.g., nerve agents]) into the environment, uniform reporting is necessary to direct appropriate resources, assess the extent of morbidity and mortality, track poisoned persons, and monitor response to intervention. (cdc.gov)
  • When illness results from an intentional or unintentional chemical release (either known or suspected on the basis of a credible threat) into the environment, uniform reporting is paramount to direct appropriate resources, assess the extent of morbidity and mortality, track poisoned persons, and monitor response to intervention. (cdc.gov)
  • Decisions to admit cancer patients to the ICU are exceptionally complex, as the chances of potentially curative cancer therapy or long-term palliation must be weighed against the associated risk of very high morbidity or mortality and thus possible futile use of more and more limited resources. (biomedcentral.com)
  • Clinical pattern a significant risk for morbidity and mortality. (who.int)
  • Road Traffic Accident represents a significant risk for morbidity and mortality in Ethiopia, of which head injury and multiple sites injury increase injury severity. (who.int)
  • Hypothermia in trauma patients is known to be a cause that increases mortality and morbidity (10). (eurarchmedres.org)
  • Predictors of disease outcomes in these patients need to be urgently assessed to decrease morbidity and societal burden. (ajemjournal.com)
  • To reduce morbidity and mortality as a result of uncontrolled hemorrhage, patients needing a massive transfusion, specifically addressed in detail later in this chapter, must be quickly identified so that immediate interventions can prevent the development of the lethal triad of coagulopathy, hypothermia, and acidosis. (medscape.com)
  • Currently, morbidity and mortality caused by surgical drainage of pseudocysts is 25% and 5%, respectively. (ahealthgroup.com)
  • Late onset nosocomial bacterial infection and septic shock in preterm very low birthweight (VLBW) infants carry a high risk of morbidity and mortality. (bmj.com)
  • Burn injury is one of the leading causes of morbidity and mortality worldwide. (iqnjm.com)
  • Pneumonia is the second most common nosocomial infection in the United States and is associated with substantial morbidity and mortality. (cdc.gov)
  • The USPSTF found adequate evidence that the well-established treatments of preeclampsia result in a substantial benefit for the mother and infant by reducing maternal and perinatal morbidity and mortality. (aafp.org)
  • Preterm birth is one of the major determinants of neonatal morbidity and mortality [ 3 ]. (biomedcentral.com)
  • This study evaluated the predictive value of blood lactate levels at admission and determined the cut-off values for predicting in-hospital mortality in the critically ill pediatric population. (biomedcentral.com)
  • The area under the curve (AUC) for APACHE II scores at 0 h for predicting in-hospital mortality and poor neurologic outcomes (cerebral performance category: 3-5) was more than 0.7, and for SOFA scores from 0 h to 48 h the AUC was less than 0.7. (accjournal.org)
  • The optimal cut-off value of peak TB on predicting in-hospital mortality was 121.2 μmol/L. Patients with post-operation TB ≥ 121 μmol/L was associated with worse long-term survival as well. (biomedcentral.com)
  • Marker of vascular endothelial dysfunction An important prognostic marker for kidney disease in diabetes mellitus in hypertension in post-streptococcal glomerulonephritis Increasing microalbuminuria during the first 48 hours after admission to an intensive care unit predicts elevated risk for acute respiratory failure, multiple organ failure, and overall mortality A risk factor for venous thromboembolism Microalbuminuria is an important adverse predictor of glycemic outcomes in prediabetes. (wikipedia.org)
  • Early recognition of children who are at high risk for mortality allows for timely changes in therapy and improves the overall outcomes. (biomedcentral.com)
  • The aim of this study was to assess the relationship between acute physiologic and chronic health examination (APACHE) II and sequential organ failure assessment (SOFA) scores and outcomes of post-cardiac arrest patients treated with therapeutic hypothermia (TH). (accjournal.org)
  • The primary outcome measure was in-hospital mortality and the secondary outcome measure was neurologic outcomes at the time of hospital discharge. (accjournal.org)
  • APACHE II, but not SOFA score, at the time of ICU admission is a modest predictor of in-hospital mortality and poor neurologic outcomes at the time of hospital discharge for patients who have undergone TH after return of spontaneous circulation following OHCA. (accjournal.org)
  • In sepsis, cell free hemoglobin correlates with outcomes in experimental models and is a predictor of survival in humans with severe sepsis. (grantome.com)
  • Accurate assessment of mortality risk and early identification of high-risk populations with poor prognoses followed by timely intervention are key in improving patient outcomes. (biomedcentral.com)
  • Therefore, the association between hyperglutaminemia and mortality outcomes was studied in a prospective, observational study. (biomedcentral.com)
  • Conventional risk scoring (Simplified Acute Physiology Score and Sequential Organ Failure Assessment) at admission, and mortality outcomes were recorded for all included patients. (biomedcentral.com)
  • Hence, it is necessary to urgently identify reliable predictors of dis- ease severity and mortality for careful allocation of healthcare re- sources and to enable earlier clinical intervention and monitoring to improve clinical outcomes. (ajemjournal.com)
  • Nine studies demonstrated prognostic value of the FOUR score in predicting mortality and functional outcomes. (springer.com)
  • Thirty-two studies demonstrated equivalency or superiority of the FOUR score compared to Glasgow Coma Score in prediction of mortality and functional outcomes. (springer.com)
  • Clinical predictors of poor outcomes in patients with sickle cell disease and COVID-19 infection. (cdc.gov)
  • 1 It has multiple subtypes and potentially serious, even fatal health outcomes. (aafp.org)
  • Disease severity was assessed using Acute Physiology and Chronic Health Evaluation (APACHE) II and Sequential Organ Failure Assessment (SOFA) scores. (biomedcentral.com)
  • All adult SLE patients (age >14 years, as per hospital policy), confirmed by SLICC criteria, and admitted due to infections (determined by quick Sequential Organ Failure Assessment or qSOFA scores) were included in the study. (medscimonit.com)
  • Sequential Organ Failure Assessment Outperforms Quantitative Chest CT Imaging Parameters for Mortality Prediction in COVID-19 ARDS. (cdc.gov)
  • Late trauma mortality peaks from days to weeks after injury and is primarily due to sepsis and multiple organ failure. (medscape.com)
  • Although significant advances in the care of the injured patient have occurred over the last decade, those who survived their initial injury continue to be plagued with the development of multiple organ failure, sepsis and their attributable morbid effects. (nattrauma.org)
  • CRRT was the most commonly used mode for many diseases, including acute kidney injury (AKI), multiple organ failure (MOF), and sepsis. (biomedcentral.com)
  • Multivariate logistic regression analysis revealed that sepsis, ALI, acute liver failure, cardiovascular hypotension, central nervous system disorders, and higher APACHE II scores were significant predictors of higher 28-day mortality. (biomedcentral.com)
  • In addition, AKI is often associated with multiple organ failure (MOF), and the mortality rate of AKI is higher when accompanied by sepsis or MOF. (biomedcentral.com)
  • The severe endothelial dysfunction that results in organ failure is now considered a hallmark of severe sepsis. (grantome.com)
  • These concepts will be considered in the context of the pulmonary endothelium and the development of acute lung injury, as lung injury arguably represents the most common clinical manifestations of organ injury in sepsis. (grantome.com)
  • Sepsis and multiple organ dysfunction were significant predictors of maternal mortality. (who.int)
  • presence of co-morbid condition/s, quality as well as the socioeconomic Study design and setting sepsis, pre-eclampsia, organ dysfunc- development of a population ( 2 ). (who.int)
  • This is derived from the multiple, critical metabolic processes with glutamine involvement, in particular for rapidly dividing cells, with important functions during sepsis and critical illness. (biomedcentral.com)
  • American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference, Definitions for sepsis and organ failure, and guidelines for the use of innovative therapies in sepsis. (jamanetwork.com)
  • Sepsis is a clinical syndrome of life-threatening organ dysfunction caused by a dysregulated response to infection. (msdmanuals.com)
  • Septic shock is a subset of sepsis with significantly increased mortality due to severe abnormalities of circulation and/or cellular metabolism. (msdmanuals.com)
  • Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. (bvsalud.org)
  • However, trauma mortality prediction in individual patients by any scoring system is limited and is in general no better than good clinical judgment. (medscape.com)
  • In contrast to these reports, a recently published clinical study conducted in a retrospective cohort suggested that the blood lactate concentration at PICU admission predicts mortality independent of the pediatric index of mortality (PIM) [ 14 ]. (biomedcentral.com)
  • In order to measure the severity and mortality of CCHF disease, scoring systems comprised of laboratory data and clinical observations have been developed. (bvsalud.org)
  • In this study, it was aimed to develop a scoring system that was easy to use and reliable, with parameters that are often looked at in clinical practice to predict mortality in CCHF disease. (bvsalud.org)
  • Patients with only minor or no clinical predictors but with poor functional capacity are recommended to undergo noninvasive testing prior to this surgery. (biomedcentral.com)
  • Clinical prediction tasks such as patient mortality, length of hospital stay, and disease diagnosis are highly important in critical care research. (biomedcentral.com)
  • 12 ] Recent small clinical studies have also demonstrated potential therapeutic effects of supplementing the fibrinolytic system, where exogenous administration of tissue plasminogen activator (tPA) resulted in improvement of respiratory function and reduced mortality in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS). (thieme-connect.com)
  • Hyperlactatemia upon admission is a documented risk factor for mortality in critically ill adult patients. (biomedcentral.com)
  • However, the predictive significance of a single lactate measurement at admission for mortality in the general population of critically ill children remains uncertain. (biomedcentral.com)
  • 0.001) were independent risk factors for mortality in critically ill children. (biomedcentral.com)
  • A high blood lactate level at admission is independently associated with and predictive of in-hospital mortality in the general population of critically ill children. (biomedcentral.com)
  • Although critical care in pediatric patients has changed dramatically over the last several decades, there has been no consistent marker for obtaining predictions of mortality in a general population of critically ill children. (biomedcentral.com)
  • Managing organ dysfunction in critically ill cancer patients requires specialized skills by the intensivist and close collaboration between the intensivist and oncologist. (springeropen.com)
  • However, their in-hospital mortality rates are not higher compared with critically ill patients with other comorbidities, such as heart failure, liver cirrhosis, or other serious chronic diseases [ 15 ]. (springeropen.com)
  • The highest mortality rates (38% and 45%, respectively) were noted for patients with a SIRS score of 4 on day 2 or 3, suggesting the importance of failure of early resuscitation to ameliorate the proinflammatory response in critically ill patients. (jamanetwork.com)
  • However, severe hyperbilirubinemia could induce oxidative stress and cell apoptosis, which cause respiratory failure, thrombocytopenia, and even neurological dysfunction, and consequently promote multiple organ dysfunction syndrome (MODS) and increase patient in-hospital mortality. (biomedcentral.com)
  • 8 ] [ 9 ] Other organs may also be affected by this form of thrombotic microangiopathy, resulting in multiple organ dysfunction syndrome and eventually death. (thieme-connect.com)
  • Serious AEs such as multiple organ dysfunction syndrome (MODS) and septic shock were commonly reported among patients who required invasive ventilation. (japsonline.com)
  • In addition, the illness takes a serious turn toward septic shock or multiple organ dysfunction syndrome (MODS). (japsonline.com)
  • Multiple organ dysfunction syndrome - is a process during which the function of many organs is altered due to serious, life-threatening disease. (ahealthgroup.com)
  • Findings that lead to an accelerated workup include multiple injuries, extremes of age, evidence of severe neurologic injury, unstable vital signs, and preexisting cardiac or pulmonary disease (see Normal Vital Signs ). (medscape.com)
  • We found an abnormal pattern of coagulation parameters and association of advanced age and comorbidities with a high rate of mortality in severe COVID-19 patients, which should be taken into consideration in their hospital management. (who.int)
  • Reported severe manifestations of P. vivax include cerebral malaria, liver dysfunction, acute kidney injury, severe anemia, acute respiratory distress syndrome, shock, abnormal bleeding, and multiple organ failure ( 2-10 ). (cdc.gov)
  • In AAD patients with severe post-operation hyperbilirubinemia, older age, lower MAP, increased blood transfusion, stage 3 AKI, the use of ECMO, and the increased peak TB lead to increase in-hospital mortality. (biomedcentral.com)
  • For patients undergoing cardiac surgery with cardiopulmonary bypass (CPB), recent study suggested that severe hyperbilirubinemia (5 times the normal upper limit) instead of mild bilirubin significantly increased patient mortality and a maximum bilirubin of 25.5 mg/dl was associated with 99% mortality [ 14 ]. (biomedcentral.com)
  • However, the mortality of patients with severe post-operation hyperbilirubinemia remained significant divergence. (biomedcentral.com)
  • It has been hypothesized that patients with severe COVID-19 have elevated levels of antifibrinolytic proteins, which create a hypofibrinolytic state, with subsequent failure of clot lysis. (thieme-connect.com)
  • Elevated LDH levels were associated with a ~6-fold increase in odds of de- veloping severe disease and a ~16-fold increase in odds of mortality in patients with COVID-19. (ajemjournal.com)
  • Death often occurs due to severe bleeding or multi organ failure. (ahealthgroup.com)
  • 95% CI 5.81, 8.06) were independent predictors of unfavorable outcome. (who.int)
  • Researchers use multiple independent variables (eg, age, injury severity) to predict the dependent variable (or outcome). (medscape.com)
  • Then we measured and recorded patients' outcome including in-hospital mortality and RRT wean-off until 30 June, 2006. (biomedcentral.com)
  • The ability to predict outcome from trauma (ie, mortality) is perhaps the most fundamental use of injury severity scoring, a use that arises from the patient's and the family's desires to know the prognosis. (medscape.com)
  • Multiple regression is advantageous because it allows one to measure the association between a predictor variable and an outcome variable while controlling for other modifying factors. (medscape.com)
  • Multiple logistic regression analysis of the pregnancy, from any cause related hospital in Alexandria, Egypt, in relation was done to determine the predictors to or aggravated by the pregnancy or its to the outcome. (who.int)
  • The primary outcome of interest was patient global outcome, as assessed by any of: mortality, modified Rankin Score, Glasgow Outcome Score, or any other functional or neuropsychiatric outcome. (springer.com)
  • The FOUR score has been shown to be a useful outcome predictor in many patients with depressed level of consciousness. (springer.com)
  • The primary outcome was all-cause mortality at 5-year follow-up. (springer.com)
  • a pooled analysis of the published literature to explore the possible as- sociation between increased LDH values and odds of disease severity and mortality in COVID-19 patients. (ajemjournal.com)
  • disease severity and mortality. (ajemjournal.com)
  • A cohort study by Hemmila et al that included 2,373,130 trauma patients reported statistically significant hospital improvements in major complications and venous thromboembolism, as well as improvements in mortality or hospice after participation in regional collaborative trauma quality improvement programs. (medscape.com)
  • In addition, little information is found in the literature to explain the recent increase in incidence of acute kidney injury and the shift toward multiple complications, specifi cally in India ( 11 ). (cdc.gov)
  • Hyperbilirubinemia is one of the common complications after cardiac surgery and is associated with increased mortality. (biomedcentral.com)
  • Advances in the management of the underlying malignancies and support of organ dysfunctions have led to survival gains in patients with life-threatening complications from the malignancy itself, as well as infectious and toxic adverse effects related to the oncological treatments. (springeropen.com)
  • It is the second leading cause of maternal mortality worldwide 7 , 8 and may also lead to other serious maternal complications, including stroke, eclampsia, and organ failure. (aafp.org)
  • Medical conditions characteristic of respiratory dysfunctions can be lethal as they disrupt the arterial oxygenation level and impair the functional supply of oxygen to major organs. (ceufast.com)
  • Due to respiratory failure and the need for ventilatory support, intensive care units (ICUs) around the world became saturated. (japsonline.com)
  • Severity of disease at ICU admission was a less important predictor of ICU resource use than necessity for specific treatment modalities. (biomedcentral.com)
  • Just as evaluation with the Hitit Index prevents unnecessary hospitalization, it can also contribute to reducing mortality rates with the early identification of CCHF cases. (bvsalud.org)
  • The overall mortality rate was 8.33% (n=2), one was treated conservatively and one surgically. (ispub.com)
  • The rates of mortality and comorbidity in patients aged ≥ 60 years were 73.7% and 78.4% compared to 26.3% and 21.6%, respectively, in patients aged (who.int)
  • In hemato-oncological patients, improvement of organ function within the first 48 hours of the ICU stay was the best predictor of 28-day survival. (biomedcentral.com)
  • A secondary aim was to explore the survival of hemato-oncological patients depending on their pre-existing comorbidities and on the severity of acute illness on admission and during the course of the ICU stay, and in comparison with a nononcological patient population with a similar degree of organ dysfunction. (biomedcentral.com)
  • In predicting the prognosis, there are several scoring indices that have been used as predictors of survival. (wikidoc.org)
  • The mortality prediction performance of this score in CCHF disease was evaluated. (bvsalud.org)
  • Multivariate analysis identified congestive heart disease and APACHE II as independent determinants for mortality. (biomedcentral.com)
  • This study shows that congestive heart disease and APACHE II were risk factors for mortality after AFB surgery. (biomedcentral.com)
  • Mean and quantiles that reflect the central tendency of physiological time series are more suitable for mortality and disease prediction. (biomedcentral.com)
  • The presence of a hemato-oncological disease per se is associated with higher ICU resource use, but not with increased mortality. (biomedcentral.com)
  • The importance of chronic kidney disease (CKD) and anaemia has not been comprehensively studied in asymptomatic patients at risk for heart failure (HF) versus those with symptomatic HF. (springer.com)
  • molecular disease regulates just more congestive than habitual management, including acetic in 32 Myosin of congestive hospitals, and while it may manage a better end than localized heart, it is extremely estimated with available nerve and poorer failure of procedure. (siriuspixels.com)
  • Predictors of cirrhosis: polymorphonuclear leukocytic elements for obtaining liver disease. (myjuicecup.com)
  • Among the initially evaluated laboratory parameters, bleeding, CURB-65 and CURB-65+B scores, the indicator with the highest predictive power for mortality was the CURB-65+B score with a cut-off value of above 3 points. (bvsalud.org)
  • Demographic data, criteria of severity, mortality in ICU, frequency of organ failure, hemodynamic and oxygenation parameters, and laboratory findings were compared in patients with septic shock according to the occurrence of DIC. (qxmd.com)
  • The initial ATIII level was the best laboratory predictor of death in these patients. (qxmd.com)
  • From the view point of an early renal support strategy, the goal of early RRT is to maintain solute clearance and fluid balance to prevent subsequent multi-organ damage, while waiting for the recovery of renal function [ 8 ]. (biomedcentral.com)
  • In-hospital mortality, long-term mortality, acute kidney injury (AKI), and the requirement of continuous renal replacement therapy (CRRT) were assessed as endpoints. (biomedcentral.com)
  • Renal (71.4%), hepatic (69.6%) and hemodynamic (62.5%) failures were the most common. (bvsalud.org)
  • Deaths occurred beyond 24 hours of hospitalization (75%), in patients with comorbidities (65.6%), peritonitis (59.4%), hemodynamic (81.2%) and renal (75%) failures. (bvsalud.org)
  • 0.001) were independent indicators for in-hospital mortality. (biomedcentral.com)
  • 0.001), the amount of blood transfusion after surgery ( P = 0.019), mean arterial pressure (MAP) in the first postoperative day ( P = 0.012), the use of extracorporeal membrane oxygenation (ECMO) ( P = 0.02), and the peak total bilirubin (TB) concentration ( P = 0.023) were independent risk factors of in-hospital mortality. (biomedcentral.com)
  • Because this attachment causes these organs to be susceptible to the toxicity of Shiga toxins, this distribution explains the involvement of the gut, kidney, and brain in STEC-associated hemolytic uremic syndrome (HUS). (marlerblog.com)
  • Early in the course of acute pancreatitis , multiple organ failure is the consequence of various inflammatory mediators that are released from the inflammatory process and from activated leukocytes attracted by pancreatic injury, the so-called systemic inflammatory response syndrome ( SIRS ). (wikidoc.org)
  • Eisenmenger syndrome was initially described in 1897, when Victor Eisenmenger reported on a patient with symptoms of dyspnea and cyanosis from infancy who subsequently developed heart failure and succumbed to massive hemoptysis. (medscape.com)
  • Blood lactate displayed a sensitivity of 61% and a specificity of 86% in predicting mortality at the optimal cut-off value of 5.55 mmol/l, and the positive and negative likelihood ratios were 4.5 and 0.45, respectively. (biomedcentral.com)
  • ALD comprises a substantial portion of the overall cirrhosis burden both in the United States (US) and worldwide and is responsible for rising rates of liver-related mortality in the US, especially amongst younger patients. (globallongevity.tv)
  • the relative contribution of ALD to all cirrhosis mortality is predicted to increase as the proportion of deaths due to HCV cirrhosis declines. (globallongevity.tv)
  • Low maternal education and inadequate antenatal care were significantly associated with maternal mortality. (who.int)
  • Participants Over 5500 solid organ transplant recipients have been enrolled in all six Swiss transplant centres by end of 2019, around three-quarter of them for kidney and liver transplants. (bmj.com)
  • One study of 75 patients admitted to the pediatric intensive care unit (PICU) found that blood lactate levels assessed at 24 hours after admission, but not at 6 hours, had better sensitivity or specificity as a predictor of death [ 15 ]. (biomedcentral.com)
  • Simplified acute physiologic score (SAPS), frequency of acquired organ failure, blood lactate, and transaminase values were significantly higher in the group DIC+. (qxmd.com)
  • In response to COVID-19 infection, activation of T cells along with massive production and release of cytokines occur with subsequent damage to internal organs, and primarily the lungs (2). (who.int)
  • Many laboratories and microbial parameter changes occur in the early phases of post burning, of which Leukocytosis can be a good predictor for infection in burns, especially when it happens in the second week and beyond. (iqnjm.com)
  • Although the initial reports showed dismal prognosis, recent data suggest that an increased number of patients with solid and hematological malignancies benefit from intensive care support, with dramatically decreased mortality rates. (springeropen.com)
  • Patient mortality prediction in intensive care units (ICUs) is a key application for large-scale health data and plays an important role in selecting interventions, planning care, and allocating resources. (biomedcentral.com)
  • The aim of the present study was to assess the amount of intensive care resources needed for, and the effect of treatment of, hemato-oncological patients in the intensive care unit (ICU) in comparison with a nononcological patient population with a similar degree of organ dysfunction. (biomedcentral.com)
  • It sustains also the treatment of failure, cardiac patients, and type. (siriuspixels.com)
  • The Pediatric Risk of Mortality III (PRISM III) scores were calculated during the first 24 hours after admission. (biomedcentral.com)
  • The patients were divided into early dialysis (sRIFLE-0 or Risk) and late dialysis (LD, sRIFLE -Injury or Failure) groups. (biomedcentral.com)
  • A regression analysis showed that hyperglutaminemia was an independent mortality predictor that added prediction value to conventional admission risk scoring and age. (biomedcentral.com)
  • Both conditions were individually and additively associated with increased 5-year mortality risk, with similar PAFs in asymptomatic patients and those with symptomatic HF. (springer.com)
  • However, SIRS criteria have been found to lack sensitivity and specificity for increased mortality risk, which is the main consideration for using such a conceptual model. (msdmanuals.com)
  • failure population: A infarction that consists other lungs off patients and sarcoplasmic diuretics and suggests the levels into Nanas( organizations). (siriuspixels.com)
  • Odds ratios used to determine associations between APACHE II scores from 0 h to 48 h and in-hospital mortality were 1.12 (95% confidence interval [CI], 1.03-1.23), 1.13 (95% CI, 1.04-1.23), and 1.18 (95% CI, 1.07-1.30). (accjournal.org)
  • From there, WBCs carry the toxin to the kidneys and other organs. (marlerblog.com)
  • Mechanisms of failed tissue oxygenation include inadequate ventilation, impaired oxygenation, circulatory collapse, and insufficient end organ perfusion. (medscape.com)
  • As a consequence, perfusion and oxygen delivery is altered and tissues are exposed to the same injurious factors, leading to parenchymal cell injury and dysfunction, and ultimately organ failure. (grantome.com)
  • 2 , 3 Although pregnant women can have other hypertensive conditions along with preeclampsia, preeclampsia is defined as new-onset hypertension (or, in patients with existing hypertension, worsening hypertension) occurring after 20 weeks of gestation, combined with either new-onset proteinuria (excess protein in the urine) or other signs or symptoms involving multiple organ systems. (aafp.org)
  • Variable-length multivariate time series means that more than one physical measurement will be collected from a patient after admission to the ICU and that the sampling frequency of each predictor differs within a given time window. (biomedcentral.com)
  • This parallel processing approach can dramatically reduce the time required to assess and stabilize a patient with multiple injuries. (medscape.com)
  • At admission, the median number of organ failures per patient was three (maximum 5). (bvsalud.org)
  • The mortality is very high. (bvsalud.org)
  • Prolonged exposure to high concentrations of ZDTPs, calcium alkyl phenates, and magnesium, sodium, and calcium sulphonates had significant effects on the reproductive organs of male rabbits (testicular atrophy and reduction or absence of spermatozoa) which appeared to be species specific. (cdc.gov)