AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth Care
Delayed Graft FunctionGraft SurvivalKidney TransplantationGraft RejectionCold IschemiaTissue DonorsOrgan PreservationCadaverImmunosuppressive AgentsLiving DonorsTransplantsGraft Occlusion, VascularIslets of Langerhans TransplantationLiver TransplantationWarm IschemiaTime FactorsBrain DeathPrimary Graft DysfunctionTreatment OutcomeCreatinineKidneyTransplantation, HomologousRetrospective StudiesTissue and Organ ProcurementPancreas TransplantationOrgan Preservation SolutionsTacrolimusCyclosporineTissue and Organ HarvestingMycophenolic AcidDeathPostoperative ComplicationsDonor SelectionPostoperative PeriodAntilymphocyte SerumFollow-Up StudiesPredictive Value of TestsReperfusion InjuryKidney Function TestsBlood Vessel ProsthesisRaffinoseAlgorithmsRisk FactorsImmunosuppressionGlomerular Filtration RateBiopsyKidney Tubular Necrosis, AcuteKidney Failure, ChronicNephrectomyLung TransplantationAzathioprineVascular PatencyPolytetrafluoroethyleneProspective StudiesKidney DiseasesComputational BiologyTransplantation, HeterotopicHistocompatibility TestingReoperationSequence Analysis, ProteinBiological MarkersAllograftsHeart TransplantationAcute DiseaseROC CurveAnastomosis, SurgicalRats, Inbred LewSoftwareRisk AssessmentIschemiaPrognosisTransplantation ToleranceMultivariate AnalysisTransplantation, IsogeneicRenal DialysisSurvival RateOliguriaComputer SimulationPolyethylene TerephthalatesLiver FailureSaphenous VeinSurvival AnalysisIncidenceAge FactorsCalcineurinKaplan-Meier EstimateBlood Vessel Prosthesis ImplantationTransplantation ImmunologyIsoantibodiesTransplantation, AutologousTechnetium Tc 99m Aggregated AlbuminProteinsCohort StudiesDiabetes Mellitus, Type 1AllopurinolDatabases, ProteinReproducibility of ResultsVeinsRenal InsufficiencyPrednisone
Coronary2023SurvivalLiver transplantationDonorsProgressionOrganAntigensVascularTransplantationPatientsClinicalAntibodiesDonor kidneyRenal functionPostoperativeCardiacBiomarkerRejectionSignificantlyUnderlying mechanismsVentricular functionTissueFunctionalDiagnosisOccurrenceInfectionRecipientsFailureTreatmentModelImpairmentsLimitationsRisk factorPhysiologicalSymptomsMyocardialKidney functionFoundExcessiveMolecularEventsEarlyAnalysisSkinFactorsContextPoor
Coronary7
  • High risk patients can be successfully treated with invasive procedures such as Percutaneous Coronary Intervention (PCI) or Coronary Artery Bypass Grafting (CABG). (biomedcentral.com)
  • Long-Term Survival, Cardiovascular, and Functional Outcomes after Minimally Invasive Coronary Artery Bypass Grafting in 566 Patients. (ottawaheart.ca)
  • Saltiel J, Lespérance J, Bourassa MG, Castonguay Y, Campeau L, Grondin P. Reversibily of left ventricular dysfunction following aorto-coronary by-pass grafts. (smw.ch)
  • CHICAGO - Coronary angiography within 2 hours of a diagnosis of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) significantly reduced the risk of recurrent ischemic events as compared to angiography delayed for 12 hours or more, based on the results of the EARLY trial presented at the American Heart Association scientific sessions. (the-hospitalist.org)
  • For non-ST-segment-elevation myocardial infarction, reperfusion is via percutaneous intervention or coronary artery bypass graft surgery. (msdmanuals.com)
  • Slightly different criteria are used to diagnose MI during and after percutaneous coronary intervention or coronary artery bypass grafting, and as the cause of sudden death. (msdmanuals.com)
  • Performance could be further improved by using summary risk prediction scores such as the EUROSCORE II for coronary artery bypass graft surgery or the GRACE risk score for acute coronary syndrome. (bvsalud.org)
20231
  • 2023). Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial. . (immunetolerance.org)
Survival10
  • Living donor kidney transplantation (LDKT) has also become a major treatment option, with living donor grafts demonstrating similar or better graft survival rates compared to deceased donors. (ekjt.org)
  • However, this practice leads to an increase in the incidence of delayed graft function (DGF) or graft primary non-function, and affects patients' long-term survival [ 3 ]. (e-ultrasonography.org)
  • A reliable and valid pre-transplant organ quality assessment to minimize unnecessary discards and maximize graft and patient survival has thus become an urgent priority. (e-ultrasonography.org)
  • The Kidney Donor Risk Index (KDRI) is the most widely used model to predict graft survival [ 4 ]. (e-ultrasonography.org)
  • The critical parameter for survival of the patient is his or her residual liver function after surgery, which is not the same as the remaining volume of the liver. (humedics.eu)
  • Background: According to literature, patient and graft survival is better in living donor renal transplants (LRT) than in cadaver renal transplants (CRT). (revistanefrologia.com)
  • Analysis showed that grafts from ECD were poorer in survival ( P = 0.013), while their recipients had comparable ( P = 0.16) survival. (biomedcentral.com)
  • The ECD-derived kidney was worse than the SCD-derived kidney in terms of graft survival and AR occurrence, and trend to an inferior renal function postoperative. (biomedcentral.com)
  • The choice of antiviral medication and duration of treatment are important considerations to ensure optimal patient outcomes and kidney graft function and survival. (lidsen.com)
  • The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. (lookformedical.com)
Liver transplantation3
  • PMID 19879295 Dhillon N, Walsh L, Krüger B, Ward SC, Godbold JH, Radwan M, Schiano T, Murphy BT, Schröppel B. A single nucleotide polymorphism of Toll-like receptor 4 identifies the risk of developing graft failure after liver transplantation. (wikipedia.org)
  • In liver transplantation, it is important to assess both the condition of the donor's liver and the urgency of the need for transplantation in the recipient - the LiMAx test can answer both these questions by determining the real-time liver function capacity of the donor and the recipient. (humedics.eu)
  • How to define initial poor graft function after liver transplantation? (humedics.eu)
Donors3
  • To overcome the shortage of kidney donors, diverse methods have been utilized, including living donor kidney transplantation (LDKT) and extended criteria for deceased donor grafts. (ekjt.org)
  • The aim of this study was to quantify renal microcirculatory perfusion in braindead donors using contrast-enhanced ultrasonography (CEUS), and to establish an accurate, noninvasive, and convenient index for predicting delayed graft function (DGF) post-transplantation. (e-ultrasonography.org)
  • CEUS may be a potential noninvasive tool for bedside examinations before organ procurement and may be used to predict early renal function after kidney transplants kidneys from donors after brain death. (e-ultrasonography.org)
Progression3
  • Novo Nordisk's Kidney Trial Success Stokes Competition Concerns Shares of biotechnology firm CSL fell to a 4-year low on Thursday, after rival Novo Nordisk's Ozempic drug showed early signs of success in delaying the progression of kidney disease in patients with diabetes. (medscape.com)
  • Our group focuses on prediction and prevention of type 1 diabetes (T1D) as well as discovery and validation of biomarkers of disease progression and response to therapy. (benaroyaresearch.org)
  • Dr Bruestle is currently investigating the interaction of Th17 cells and neutrophils and the direct pathological effects of NETs on neurons and the kind of damage seen in MS. She uses genetic- and inhibitor-mediated manipulation of Th17 cell and/or neutrophil function to explore potential drug targets for MS and to identify molecules involved in this process as biomarkers for disease progression and treatment efficacy. (aips.net.au)
Organ2
  • Because of transportation limitations, the time delay from organ procurement to actual transplantation is one of the most critical barriers to DDKT in Jeju. (ekjt.org)
  • It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (lookformedical.com)
Antigens1
  • or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (lookformedical.com)
Vascular2
  • Obstruction of flow in biological or prosthetic vascular grafts. (lookformedical.com)
  • Chest radiographic findings indicative of pulmonary venous hypertension may occur late and persist because of delay in fluid shifts among vascular, interstitial, and alveolar spaces. (medscape.com)
Transplantation1
Patients6
  • KidneyWeek 2022 Balanced Crystalloid Fluids Surpass Saline for Kidney Transplant Low chloride, balanced-crystalloid IV fluid led to significantly fewer delayed graft function events compared with saline in a multicenter trial of patients getting a deceased-donor kidney transplant. (medscape.com)
  • The test has been applied in studies to examine the variation of liver function capacity in patients with liver disorders, including cirrhosis, alcoholic liver disease, viral hepatitis, or non-alcoholic fatty liver disease (NAFLD). (humedics.eu)
  • The LiMAx test has also been applied in patients receiving bariatric surgery to evaluate the improvement of liver function capacity and treatment efficacy. (humedics.eu)
  • Some patients were not cooperative in wearing the brace, in which case best results were obtained by using a fullthickness skin graft in the release site. (medbc.com)
  • Delay in revascularization is associated with increased mortality rate in patients with severe left ventricular dysfunction and viable myocardium on fluorine 18-fluorodeoxyglucose positron emission tomography imaging. (smw.ch)
  • The EARLY trial randomized 740 patients at 16 hospitals in France with NSTE-ACS to one of two timing strategies for intervention: within 2 hours of diagnosis, the early-intervention group, and between 12 and 72 hours after diagnosis, the delayed group. (the-hospitalist.org)
Clinical1
  • More than 35 years of this work recently led to the first FDA approved disease modifying therapy to delay the onset of T1D in at risk individuals, setting a precedent for treatment before the clinical appearance of other autoimmune diseases as well. (benaroyaresearch.org)
Antibodies1
  • At least 1 kidney recipient experienced delayed development of detectable hepatitis A anti-IgM antibodies. (cdc.gov)
Donor kidney1
  • The geography and resulting transportation limitations of Jeju place it at risk for prolonged cold ischemia time (CIT) in deceased donor kidney transplantations, especially in marginal donor grafts. (ekjt.org)
Renal function1
Postoperative1
  • The LiMAx test: a new liver function test for predicting postoperative outcome in liver surgery. (humedics.eu)
Cardiac1
  • Besides, results showed cardiac arrest (uncontrolled vs. controlled, HR 2.49, P = 0.049), HLA mismatch (4-6 loci vs. 0-3 loci, HR 3.61, P = 0.039), and AR occurrence (HR 2.91, P = 0.006) were demonstrated to be independent risk factors for graft loss. (biomedcentral.com)
Biomarker1
  • Given the limitations of serum creatinine as a biomarker of kidney function, different urinary and serum proteins, molecules, and, most recently, microRNAs have been rigorously investigated over the past decade as possible biomarkers for kidney disease. (medscape.com)
Rejection1
Significantly1
  • The best use of AG was seen as a dressing for skin grafts, when it was found to be significantly superior to Furacin, with improved graft take and reduced pain. (medbc.com)
Underlying mechanisms1
  • While trees do not actively 'choose' neighbours to graft to, our findings point to the existence of underlying mechanisms that regulate 'optimal group size' selection related to resource use within cooperating networks. (nature.com)
Ventricular function2
  • The opening of an infarct-related artery may improve ventricular function, collateral blood flow, and ventricular remodeling, and it may decrease infarct expansion, ventricular aneurysm formation, left ventricular (LV) dilatation, late arrhythmia associated with ventricular aneurysms, and mortality. (medscape.com)
  • Imaging is also useful in detecting pericardial effusion, concomitant valvular or congenital heart disease, and marked depression of ventricular function that may interdict treatment in the acute phase with beta-adrenergic blockers. (medscape.com)
Tissue1
  • An induced state of non-reactivity to grafted tissue from a donor organism that would ordinarily trigger a cell-mediated or humoral immune response. (lookformedical.com)
Functional3
  • Still, even if grafts are non-functional, they can increase tree stability as compared to non-grafted trees by sharing anchoring systems 5 . (nature.com)
  • The functional ecology of root grafts in wetland forests, and the effect of environmental stress on network topology remains unexplored. (nature.com)
  • An increase in the serum creatinine level represents a delayed indication of a functional change in GFR that lags behind structural changes that occur early in AKI. (medscape.com)
Diagnosis1
Occurrence1
  • The occurrence of natural root grafts, the union of roots of the same or different trees, is common and shared across tree species. (nature.com)
Infection1
  • AG is recommended as a dressing for skin grafts, provided that there is no excessive risk of infection. (medbc.com)
Recipients1
  • Recipients were divided into DGF and non-DGF groups according to early post-transplant graft function. (e-ultrasonography.org)
Failure3
  • Serum creatinine measurement is not reliably indicative of underlying pathophysiology (ie, it does not allow differentiation of hemodynamically mediated changes in kidney function, such as prerenal azotemia from intrinsic renal failure or obstructive uropathy from structural kidney damage). (medscape.com)
  • This allows for better risk assessment in liver surgery through precise risk prediction of liver failure and residual post-operative liver function. (humedics.eu)
  • Securing Transplanted Meniscal Allografts Using Bone Plugs Results in Lower Risks of Graft Failure and Reoperations: A Meta-analysis. (mayo.edu)
Treatment4
  • Recurrence rates were 81 per cent after treatment with Z-plasties and 62 per cent after releasing incisions with split thickness skin grafts. (medbc.com)
  • The primary end point of this study was to investigate the influence of a multicomponent treatment on microvascular function. (statsignaling.com)
  • Early ACLR and Risk and Timing of Secondary Meniscal Injury Compared With Delayed ACLR or Nonoperative Treatment: A Time-to-Event Analysis Using Machine Learning. (mayo.edu)
  • Upon conservative treatment, full recovery was achieved and normal function of the right upper limb was observed 3 months following the operation. (magiran.com)
Model5
  • A retinal aging score based on a deep-learning prediction model is associated with the risk of developing end-stage kidney disease. (medscape.com)
  • A new index for the joint prediction model of three variables, the contrast-enhanced ultrasonography/Kidney Donor Profile index (CEUS-KDPI), was developed. (e-ultrasonography.org)
  • Such biological realism coupled with mathematical and computer simulation can provide modelling constructs with improved properties for model-based extrapolation and prediction. (eacpt.org)
  • DVMRP Model 26 7.1 Init 26 7.2 Idle 26 7.3 Probe_Send State 26 7.4 Report_Send 26 7.5 Prune _Send 26 7.6 Graft_send 27 7.7 Arr_Pkt 27 7.8 Route_Calc 28 7.9 Timer 28 8. (irt.org)
  • When designing a risk prediction model, patient-proximate variables with a sound theoretical or proven association with the outcome of interest should be used. (bvsalud.org)
Impairments2
  • Activated microglia and subsequent release of pro-inflammatory cytokines result in neuroinflammatory status which further damage neurological function including cognitive impairments in various neurological conditions. (imperial.ac.uk)
  • Impairment of the ability to coordinate the movements required for normal ambulation (WALKING) which may result from impairments of motor function or sensory feedback. (lookformedical.com)
Limitations1
  • In particular, the limitations of machine learning prediction models should be understood, and these models should be appropriately developed, evaluated and reported. (bvsalud.org)
Risk factor1
Physiological2
  • She will then study how neurons grow, form connections and consequently re-attain their physiological circuit functions. (aips.net.au)
  • Besides generating vision, light modulates various physiological functions, including mood. (researchgate.net)
Symptoms1
  • Common signs and symptoms may stem from decreased hepatic synthetic function (eg, coagulopathy), portal hypertension (eg, variceal bleeding), or decreased detoxification capabilities of the liver (eg, hepatic encephalopathy). (medscape.com)
Myocardial1
  • Persistent stunning induces myocardial hibernation and protection: flow/function and metabolic mechanisms. (smw.ch)
Kidney function4
Found3
  • Although abundant APA reprogramming is found in kidney renal clear cell carcinoma (KIRC), which is one of the major malignancies, whether APA functions in KIRC remains unknown. (bvsalud.org)
  • MORC2 was found to function in KIRC by downregulating tumor suppressor DAPK1 via DNA methylation. (bvsalud.org)
  • Grafted trees were found to dominate the upper canopy of the forest, and as the probability of grafting and the frequency of grafted groups increased with a higher environmental stress, the mean number of trees within grafted groups decreased. (nature.com)
Excessive1
  • Unlike Windows XP, again, typically employed in an attempt to mitigate this problem, but if the delay spread is excessive, then most equalizers will not be capable of properly handling the multipath effects. (binaryoptiontradingscam.com)
Molecular1
  • The evolution history suggests that PPO genes from different organisms may share conserved molecular functions. (bild-schoen.com)
Events1
  • Regarding secondary endpoints, rates of recurrent ischemic events were 2.9% for the early group and 19.8% for the delayed group during hospitalization, and 4.1% vs. 20.7% at 30 days. (the-hospitalist.org)
Early4
  • While early research suggested negative effects of root grafting with the risk of pathogen transmission, recent evidence supports the hypothesis that it is an adaptive strategy that reduces stress by facilitating resource exchange. (nature.com)
  • The early group received angiography within 2 hours, and a delayed group received angiography 12 or more hours after NSTE-ACS. (the-hospitalist.org)
  • The MACE rate was 4.4% in the early group and 21.3% in the delayed group. (the-hospitalist.org)
  • On average, angiography was done within 1 hour in the early group and at 18 hours in the delayed group. (the-hospitalist.org)
Analysis1
  • RFC 2490 IP Multicast with RSVP January 1999 simulation of IPmc with RSVP has been generally available for analysis of the performance and prediction of the behavior of these protocols. (irt.org)
Skin4
  • An investigation was made of the ability of this new type of gauze to act as a dressing for skin graft donor sites, partial-thickness burn injuries, and split-thickness skin grafts. (medbc.com)
  • The control dressings used for comparative purposes were as follows: fine mesh gauze for the skin graft donor sites, silver sulphadiazine (Silvadene) on coarse mesh gauze for the partial-thickness burns, and nitrofurazone (Furacin) on fine mesh gauze for the skin grafts. (medbc.com)
  • The recurrence rate was reduced, following skin grafting, to 17 per cent by the use for one year of a neck hyperextension brace. (medbc.com)
  • The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin. (lookformedical.com)
Factors1
  • The arrival time of the kidney segmental artery (12.33 seconds) and cortex (14.34 seconds), and the time interval between the time to peak of segmental artery and cortex (0.04 seconds) were independent factors associated with delayed graft function (DGF). (e-ultrasonography.org)
Context1
  • Context: Focusing on mitochondrial function and thyroid tumorigenesis, we used an integrative approach to identify relevant biomarkers for borderline thyroid lesions. (statsignaling.com)
Poor1
  • The overall prognosis of BPIs iscommonly satisfactory, but the poor function of the upper limb may not be fully recovered in all cases and may end in the permanent sequel in serious injuries. (magiran.com)