• trans -2-Aryl-3-nitro-cyclopropane-1,1-dicarboxylates undergo ring-opening rearrangement and the Nef reaction in the presence of BF 3 OEt 2 to give aroylmethylidene malonates. (organic-chemistry.org)
  • 7. A capsule according to the any of the preceding claims wherein the precursor is product of the reaction of a beta-keto ester and an aldehyde. (sumobrain.com)
  • Reaction with a nucleophile followed by removal of the malonate portion of the molecule via oxidation produces the desired secondary amine. (acs.org)
  • In fact, benzoins can be used instead of aldehydes as substrates to achieve the same overall Stetter transformation, because benzoins can be restored to their aldehyde precursors under the reaction conditions. (wikipedia.org)
  • It decomposes in a first-order reaction: CH3N3 → CH3N + N2 Methyl azide might be a potential precursor in the synthesis of prebiotic molecules via nonequilibrium reactions on interstellar ices initiated by energetic galactic cosmic rays (GCR) and photons. (wikipedia.org)
  • In other syntheses, pimelic acid is made from cyclohexene-4-carboxylic acid, and a fourth method also exists based on the 1,4 reaction of malonate systems with acrolein. (wikipedia.org)
  • β-alanine can undergo a transanimation reaction with pyruvate to form malonate-semialdehyde and L-alanine. (wikipedia.org)
  • The Knoevenagel condensation is a key step in the commercial production of the antimalarial drug lumefantrine (a component of Coartem): The initial reaction product is a 50:50 mixture of E and Z isomers but because both isomers equilibrate rapidly around their common hydroxyl precursor, the more stable Z-isomer can eventually be obtained. (wikipedia.org)
  • Non-cyclic products from this starting material include: The anticonvulsant valproic acid Ethyl cyanoacrylate, used as superglue, via reaction with formaldehyde Ethyl cyanoacetate is also used to prepare 3,3-diphenylpropan-1-amine, which is the precursor used in the synthesis of Prenylamine & Droprenilamine. (wikipedia.org)
  • Malonate decarboxylase holo-(acyl-carrier protein) synthase (EC 2.7.7.66, holo ACP synthase, 2'-(5-triphosphoribosyl)-3'-dephospho-CoA:apo ACP 2'-(5-triphosphoribosyl)-3'-dephospho-CoA transferase, MdcG, 2'-(5-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase adenylyltransferase, holo-malonate-decarboxylase synthase) is an enzyme with systematic name 2'-(5-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase 2'-(5-phosphoribosyl)-3'-dephospho-CoA-transferase. (wikipedia.org)
  • Malonyl CoA is formed from acetyl CoA by the action of acetyl-CoA carboxylase, and the malonate is transferred to an acyl carrier protein to be added to a fatty acid chain. (wikipedia.org)
  • Since malonate 1 already possessed the two azide groups within its core, it appeared to be the ideal precursor molecule. (rsc.org)
  • Though there are no crystal structures with a LPA molecule in the substrate pocket, the crystal structure with malonate shows the hydrogen bonding between the enzyme residues and the carbonyl groups that would stabilize the phosphate and hydroxyl groups on the LPA. (wikipedia.org)
  • The one he came up with is easy to make-Kürti's lab regularly prepares its precursor ketone in 400-g quantities. (acs.org)
  • 1. A capsule comprising an odourant oil core surrounded by polymeric capsule wall, the capsule wall being formed of a polymer containing recurring nitrogen to carbonyl carbon bonds wherein the oil core contains an aldehyde precursor. (sumobrain.com)
  • 4. A capsule according to any of the preceding claims wherein the precursor is a precursor of an aldehyde having no substituents at the carbon atoms alpha or beta to the aldehyde carbonyl carbon atom. (sumobrain.com)
  • 5. A capsule according to any of the preceding claims wherein the oil core contains an aldehyde precursor of an aldehyde which has no substituents at the carbon atoms alpha or beta to the aldehyde carbonyl carbon atom, and a perfume ingredient, which has free aldehyde functionality, which ingredient is an aldehyde substituted at the carbon atom alpha or the beta to the aldehyde carbonyl carbon atom. (sumobrain.com)
  • 9. A capsule according to any of the claims 1 to 6 wherein the precursor is a Schiff base of an aldehyde. (sumobrain.com)
  • 11. A method according to claim 10, said method comprising the step of identifying those ingredients forming the oil core that contain aldehyde functionality, and of those ingredients, converting those having no substituents at the carbon atoms alpha or beta to the aldehyde carbonyl carbon atom into the corresponding precursor prior to encapsulation. (sumobrain.com)
  • On the other hand, intermolecular asymmetric reactions are quite confined to specifically matched combinations of acyl anion precursor and Michael acceptor, such as an aliphatic aldehyde with a nitroalkene. (wikipedia.org)
  • 14. A method of reducing aggregation of a plurality of capsules of claim 1 comprising the step of encapsulating an oil in a capsule, by converting any aldehyde-containing oil core ingredients into a precursor therefor, prior to encapsulation. (patentsencyclopedia.com)
  • The incorporation of radioactivity from [2- 14 C]malonate into fatty acids and the labeling of ACP were inhibited by cerulenin and required ATP and Mg 2+ . (pnas.org)
  • The present invention is directed toward an injectable, single- or multiple-component polymeric liquid precursor of an in situ-forming, non-absorbable, flexible, and resilient hydrogel or semi-solid that can be used in non-surgical, minimally invasive treatment of herniated disc. (google.com)
  • This invention relates to injectable polymeric precursors of an in situ-forming, non-absorbable hydrogel or semi-solid for replacing or augmenting the intervertebral discus nucleus pulposus. (google.com)
  • Hutchinson's group went on to develop methods to improve the yield of DXR, from the fermentation process used in its commercial production, not only by introducing Dox A encoding plasmids, but also by introducing mutations to deactivate enzymes that shunt DXR precursors to less useful products, for example baumycin-like glycosides. (wikipedia.org)
  • this salt can react with any alkyl halide which may be the same as or different from, the first alkyl halide to yield a dialkyl malonate . (infobarrel.com)
  • A single nucleophilic attack from a Grignard reagent on a malonate-derived imine leads to an unsymmetrical secondary amine product (top), while a double attack from the same Grignard on the related oxime produces a symmetrical secondary amine (bottom). (acs.org)
  • Chemists, led by László Kürti of Rice University, Daniel H. Ess of Brigham Young University, and Guigen Li of Nanjing University and Texas Tech University, have come up with a series of imines and an oxime-all derived from malonate-in which normally nucleophilic nitrogen becomes an electrophile. (acs.org)
  • The PKS is first loaded with Acetyl-CoA and elongated with methyl-malonate units to arrive at the precursor 2. (wikipedia.org)
  • This was accomplished from non-aromatic precursors, with the source of the ¹³C-atom being [¹³C]methyl iodide. (bl.uk)
  • synthesized a photo sensitive precursor 86 to phenylsulfanylcarbene 87 (Scheme 4.39) . (123doc.org)
  • The precursors for the new ligands were synthesized via a modular scheme that allows for facile diversification. (umontreal.ca)
  • The malonate additive was employed in the catalytic oxidative heterocoupling of electronically dissimilar 2-naphthols. (umontreal.ca)
  • The total synthesis of Portentol utilized a proposed double cyclization cascade beginning with precursor 2, cyclization to intermediate 3, and ending with the formation of PortentolThe stereoisomer of Portentol with respect to C7 was not observed. (wikipedia.org)
  • The compounds [3-(2-Bromocyclohex-2-enyloxy)prop-1-ynyl]- tert -butyl-dimethylsilane 3 , [4-(2-bromocyclohex-2-en-1-yloxy)but-2-yn-1-yloxy]tert-butyldimethylsilane 5 and dimethyl 2-(2-bromocyclohex-2-enyl)-2-(3-( tert -butyldimethylsilanyl)prop-2-ynyl)malonate 9 were prepared and subjected to palladium-catalyzed intra-intermolecular cascade cross couplings incorporating bicyclopropylidene 10 under two types of conditions. (mdpi.com)
  • Two major routes for the synthesis of 2-bromo-1,6-enynes as precursors for palladium-catalyzed cascade cyclizations have previously been developed [ 32 ]. (mdpi.com)
  • Through detection of (1,8a-trans)-1-hydroxyindolizidine and (1,8a-trans-1,2-cis)-1,2-dihydroxyindolizidine-two precursors of swainsonine in the fungus pathway-in the shoots of the plant, Harris et al. (wikipedia.org)
  • Doxorubicin (DXR) is a 14-hydroxylated version of daunorubicin, the immediate precursor of DXR in its biosynthetic pathway. (wikipedia.org)
  • It is found in asparagus and is believed to be the metabolic precursor to odorous sulfur compounds responsible for the distinctive smell of urine which has long been associated with eating asparagus. (wikipedia.org)
  • les additifs à base de pyridine ont fourni des énantiosélectivités modérées tandis que les additifs à base de malonate ont donné des meilleurs rendements de la réaction de couplage oxydatif. (umontreal.ca)
  • Ultérieurement, les additifs à base de malonate ont été appliqués envers l'hétérocouplage de 2-naphthols. (umontreal.ca)
  • β-Alanine is the rate-limiting precursor of carnosine, which is to say carnosine levels are limited by the amount of available β-alanine, not histidine. (wikipedia.org)