• Amyloid precursor protein (APP) is a transmembranal protein which is thought to regulate transcription. (proteopedia.org)
  • Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. (proteopedia.org)
  • 86 (1) A licensed dealer and a registered dealer shall, on becoming aware of the transaction, make a record of every transaction occurring in the course of their activities in respect of which there are reasonable grounds to suspect that the transaction is related to the diversion of a precursor to an illicit market or use. (gc.ca)
  • d) a detailed description of the reasons for suspecting that the transaction is related to the diversion of a precursor to an illicit market or use. (gc.ca)
  • In accordance with the Board's mandate under the United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances of 1988, the annual reports on precursors provide an overview of the most important actions taken to implement article 12 of that Convention and to strengthen the functioning of the international precursor control system in any given year. (incb.org)
  • Often referred to as "cooks," these producers synthesize the precursors into illicit synthetic drugs that are then sold to large buyers and transport specialists. (insightcrime.org)
  • The reports also provide a detailed account of the latest trends and developments in legitimate international trade and in trafficking in precursor chemicals under international control, as well as their non-scheduled substitutes and alternatives. (incb.org)
  • The raw materials for these drugs are chemicals referred to as precursors. (insightcrime.org)
  • The sources for these precursor chemicals span the globe. (insightcrime.org)
  • They are currently concentrated in China, where a relatively small number of companies appear to be producing precursor chemicals, in mainly two provinces. (insightcrime.org)
  • This article is part of a year-long investigation that tracked the supply chain of precursor chemicals that aid in the production of methamphetamine and fentanyl in Mexico. (insightcrime.org)
  • A vast number of what are termed "precursor" chemicals assist in the production of synthetic drugs. (insightcrime.org)
  • Our preliminary data suggests that grafting interneuron precursors into the postnatal rodent brain allows for up to a 35% increase in the number of cortical interneurons. (ca.gov)
  • Although spontaneous changes of [Ca 2+ ] i have been examined in immature cortical neurons, the calcium dynamics of cortical precursor cells have received less attention. (jneurosci.org)
  • These results demonstrate distinct patterns of spontaneous [Ca 2+ ] i change in cortical precursor cells and raise the possibility that these dynamics may contribute to the regulation of neurogenesis. (jneurosci.org)
  • The lack of proven screening tools for early detection and the high mortality of ovarian serous carcinoma (OSC), particularly high grade, have focused attention on identifying putative precursor lesions with distinct morphological and molecular characteristics. (hindawi.com)
  • A lack of effective screening tools for early detection of ovarian cancer in high-risk and general populations has led to increased interest in the identification of precursor lesions defined by both morphological and molecular changes that could be the target of not only early detection but prevention efforts. (hindawi.com)
  • The morphological characteristics of these cells and immunohistochemical staining suggested that the coordinated events occurred in gap junction-coupled precursor cells. (jneurosci.org)
  • Combining anatomical information of the new species with other dinosaur and pterosaur precursors shows that morphological disparity of precursors resembles that of Triassic pterosaurs and exceeds that of Triassic dinosaurs . (bvsalud.org)
  • Oligodendrocytes, the myelinating cells of the central nervous system (CNS), are generated from oligodendrocyte precursor cells (OPCs) that express neurotransmitter receptors. (nature.com)
  • Towards the therapeutic development of inhibitory neuron precursor transplantation for human neurological disorders, we have made significant progress in the differentiation of these cells from human ESCs and will complete optimization of this protocol. (ca.gov)
  • During this first year, we have made considerable headway in the optimization of the human interneuron precursor differentiation protocol, verified functional engraftment of these cells in mice, and begun to collect dose, safety and efficacy data for rodent-derived interneuron transplantation. (ca.gov)
  • As we continue to optimize our ES cell differentiation protocol, these primary interneuron precursors will enable initial human cell dose response and behavior experiments and, along with rodent-derived cells, will provide important baseline measures. (ca.gov)
  • If the pathway of differentiation is not followed, characteristic lesions result, and such lesions are regarded as the formal histogenetic precursors of melanoma. (nih.gov)
  • Such a developmental flaw is termed aberrant differentiation, and the resultant precursor lesion is designated melanocytic dysplasia. (nih.gov)
  • Myeloid-related precursor neoplasms derive from precursor cells that have at least one form of myeloid differentiation. (medscape.com)
  • the tumor derives from the precursors of plasmacytoid dendritic cells (ie, plasmacytoid monocytes). (medscape.com)
  • Researchers at the school have devised a way to efficiently coax the cells to become human germ cells -- the precursors of egg and sperm cells -- in the laboratory. (sciencedaily.com)
  • These dosing and safety data will then serve as the baseline for comparison with human interneuron precursors and inform design of preclinical studies of these cells in immunosuppressed mice. (ca.gov)
  • We have also compared the behavior of primary fetal cells to these human interneuron precursor-like cells both in vivo and in vitro. (ca.gov)
  • During the reporting period, we have developed methods to enable the optimization of inhibitory nerve precursor cell, or MGE cell, derivation from human pluripotent stem cells (hPSCs). (ca.gov)
  • Gibco Rat Glial Precursor Cells are isolated and cryopreserved from the cortex of newborn Sprague Dawley Rats. (thermofisher.com)
  • A flexible, ready-to-use, and quality alternative to fresh precursor cells, each vial contains 1 million cells per mL. (thermofisher.com)
  • Immunohistochemical staining confirmed that these events occurred primarily in precursor cells rather than in postmitotic neurons. (jneurosci.org)
  • During this time, precursor cells undergo interkinetic nuclear migration ( Seymour and Berry, 1975 ) in which cells in the DNA synthetic S phase have their nuclei in the upper third of the VZ. (jneurosci.org)
  • Both intrinsic and extrinsic signals are likely to influence the proliferative potential and eventual fates of precursor cells within the VZ. (jneurosci.org)
  • The literature review shows that cognitive precursors of reading and writing, with emphasis on phonological awareness letters name knowledge can be developed by the children in family context, before the beginning of formal education, with positive effects on reading and writing performance as well as beginning formal schooling. (bvsalud.org)
  • Though many modalities of psychotherapy include these ideas, 'Already Well' focuses on, and makes explicit, this miraculous synthesis (wellness) as the precursor for growth and change. (goodtherapy.org)
  • To the best of our knowledge, no report is yet available in the literature on the synthesis of cobalt incorporated pyramidal shaped hematite in using PVA in the precursor. (scirp.org)
  • This entry was posted on Wednesday, February 16th, 2022 at 8:53 pm and is filed under Hacking , precursor . (bunniestudios.com)
  • Aaron counsels a variety of manufacturers, importers, and users of chemical products that contain controlled substance precursors (e.g. (bdlaw.com)
  • The department's Precursor Chemical / Laboratory Apparatus program oversees the record keeping and reporting requirements of Texas Health and Safety Code Sections 481.077 - 481.080. (texas.gov)
  • The specific targeting of precursor proteins synthesized in the cytosol to various cell organelles is a central aspect of intracellular protein traffic. (nih.gov)
  • PTMs from this list in conjunction with a protein sequence and a few precursor masses. (lu.se)
  • And while the hunt for glycine has had a long and inconclusive history, the identification of amino acetonitrile gives us a molecule chemically related to glycine, one whose status as an amino acid precursor is argued in the paper on this work. (centauri-dreams.org)
  • Adolescent precursors of cannabis dependence: findings. (cambridge.org)
  • HOUSTON - Mars One, the Dutch nonprofit focused on the proposed human settlement of the red planet by the mid-2020s, has selected a Portuguese/Spanish/Dutch university level student team to carry out a plant growth experiment aboard an unmanned lander precursor mission it plans to launch in 2018. (aviationweek.com)
  • All of the transformations of the Miranda de Ebro plant are carried out with Montefibre Carbon's proprietary technology, which is based on the original development of precursor fiber by Monsanto at the end of the 1950s in Knoxville, Tenn. (nawindpower.com)
  • For references , please go to https://www.eea.europa.eu/data-and-maps/figures/sector-split-of-emissions-of-ozone-precursors-eu-10 or scan the QR code. (europa.eu)
  • In this work, the preparation strategy of iron oxide from foam-based precursor is reported for the first time. (scirp.org)
  • The experiments underway will yield insights that will be critical to the development of a clinical trial using human interneuron precursors. (ca.gov)
  • For the data analysis nonparametric Spearman correlation related parental encouragement to the development of precursors of reading and writing and the Mann-Whitney tests showed that stimulating the development of predictors of reading and writing contributed significantly to children´s performance. (bvsalud.org)
  • Now researchers from the Max Planck Institute for Radio Astronomy in Bonn have detected amino acetonitrile (NH 2 CH 2 CN), a potential precursor of the simplest amino acid, glycine. (centauri-dreams.org)
  • To obtain the final product, the precursor was calcined at 600˚C in air atmosphere. (scirp.org)
  • Stem cell leukemia/lymphoma (SCLL), which is also known as the 8p11 myeloproliferative syndrome (EMS), is characterized in its typical form by the occurrence, either simultaneously or sequentially, of a bcr/abl-negative myeloproliferative disorder and a lymphoma, usually a precursor T-cell lymphoblastic lymphoma. (medscape.com)
  • The goal of the research in progress here is to ultimately prepare human interneuron precursors for clinical trials. (ca.gov)
  • Explain how neurobiological and scientific research supports the value of self-acceptance as a precursor to ongoing health and wellness. (goodtherapy.org)
  • still used by carbon fiber producers), but has been improved through more than 20 years of research into PAN precursors by the Montefibre group. (nawindpower.com)
  • The relevance of this study is based on the importance of research on the environment in which initial learning takes place, to encourage parents activities and to help formulating social and educational policies to explore the precursors of reading and writing. (bvsalud.org)
  • The Precursors is a video game from Ukrainian developer Deep Shadows. (wikipedia.org)
  • As a test, I made a one hour video that walks through the Precursor tech stack, from hardware to root keys. (bunniestudios.com)
  • We consider the possibility that preparations to return later are already made during precursor fixations. (lu.se)
  • http://www.russobit-m.ru/catalogue/item/predtechi/ Archived 2008-10-20 at the Wayback Machine The Precursors at Russobit-M http://uk.xbox360.ign.com/objects/825/825295.html The Precursors summary Rossignol, Jim (4 January 2011). (wikipedia.org)
  • Together, these data will provide essential information for developing a plan for clinical trials using human interneuron precursors. (ca.gov)
  • Instead, we found many slow-slip precursors - starting miles from the epicenters and migrating across the fault. (newswise.com)
  • We have since reexamined the behavior of 3a, 6a-dimethylglycoluril (one of the adducts of urea and diacetyl) and found that indeed this compound might be a precursor of ethyl carbamate in wines. (avf.org)
  • c) the name and quantity of any Class A precursor that has been lost or wasted in the course of conducting authorized activities during the calendar year. (gc.ca)
  • This paper describes some everyday practices of parents and child, especially related to reading, in two distinct social classes, and its relationship to children's performance at precursors of reading at the last year from kindergarten. (bvsalud.org)
  • The precursor industry - and the synthetic drug industry writ large - is so challenging to disrupt precisely because it works across legal and illegal spheres, involves many layers and different criminal networks, and has many means to obtain its final objective: the sale of synthetic drugs to an increasing number of consumers. (insightcrime.org)
  • Their distinct biosynthetic activity includes an endoperoxidase synthase reaction that oxygenates and cyclizes polyunsaturated fatty acid precursors (eg, arachidonic acid) to form prostaglandin G 2 (PGG2), and a peroxidase reaction that converts PGG2 to prostaglandin H 2 (PGH2), as shown below. (medscape.com)
  • This process would mark precursor fixations as a special category of fixations, that is, distinct in neural activity from other fixation categories such as refixations and fixations to locations visited only once. (lu.se)
  • Double distilled water was used as a solvent to prepare the precursor solution. (scirp.org)
  • there's a new Precursors patch on Mod DB and The Patches Scrolls to update Deep Shadows' shooter to version 1.7. (wikipedia.org)
  • Our group was a little surprised to see so many precursors," Barcheck said. (newswise.com)
  • This investigation sought to understand the flow of these precursors for the production of synthetic drugs in Mexico, specifically methamphetamine and fentanyl. (insightcrime.org)
  • Montefibre Carbon produces large and ultra-large precursor fiber for use in high-volume, cost-sensitive mass markets, such as automotive, marine and wind energy applications. (nawindpower.com)
  • Independent of the effect of saccade length, EEG amplitude was enhanced in precursor fixations compared with the other fixation categories 200 to 400 ms after fixation onsets, most noticeably over the occipital areas. (lu.se)