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  • enzyme
  • Overexpression of both the cysteinyl leukotriene receptor 1 and the leukotriene C4 synthase enzyme has been shown in respiratory tissue from patients with aspirin-induced asthma, which likely relates to the increased response to leukotrienes and increased production of leukotrienes seen in the disorder. (wikipedia.org)
  • Aspirin inhibits the activation of kallenogen by interfering with the formation of kallikrein enzyme which is essential in the process of activation. (wikipedia.org)
  • nonsteroidal
  • Aspirin-induced asthma, also termed Samter's triad, Samter's syndrome, aspirin-exacerbated respiratory disease (AERD), and recently by an appointed task force of the European Academy of Allergy and Clinical Immunology/World Allergy Organization (EAACI/WAO) Nonsteroidal anti-inflammatory drugs-exacerbated respiratory disease (N-ERD). (wikipedia.org)
  • pain
  • Effervescent formulations of aspirin, such as Alka-Seltzer or Blowfish, relieve pain faster than aspirin in tablets, which makes them useful for the treatment of migraines. (wikipedia.org)
  • Topical aspirin may be effective for treating some types of neuropathic pain. (wikipedia.org)
  • mild
  • The respiratory reactions to aspirin vary in severity, ranging from mild nasal congestion and eye watering to lower respiratory symptoms including wheezing, coughing, an asthma attack, and in rare cases, anaphylaxis. (wikipedia.org)
  • alcohol
  • Use caution with a history of GI disease (bleeding or ulcers), concurrent therapy with aspirin, anticoagulants and/or corticosteroids, smoking, use of alcohol, the elderly or debilitated patients. (wikipedia.org)
  • combination
  • In order to compare the therapeutic effects of AEE and its precursors, aspirin, eugenol and a combination of aspirin and eugenol were designed at the same molar quantities as the AEE medium dose in the control group. (springer.com)
  • however
  • The word Aspirin was Bayer's brand name, however their rights to the trademark were lost or sold in many countries. (wikipedia.org)
  • risk
  • In the United States low dose aspirin is deemed reasonable in those between 50 and 70 years old who have a more than 10% risk of cardiovascular disease and are not at an increased risk of bleeding who are otherwise healthy. (wikipedia.org)
  • active
  • Thus, 15(S)-HETE and 15(S)-HpETE, in addition to having intrinsic biological activities, are key precursors to numerous biologically active derivatives. (wikipedia.org)
  • important
  • By using potassium hydroxide, 4-hydroxybenzoic acid is accessible, an important precursor for the versatile paraben class of biocides used e.g. in personal care products. (wikipedia.org)
  • sometimes
  • In acknowledgement of the role played by aspirin-treated cyclooxygenase 2 in forming these products, the epi-lipoxins are sometimes termed ATL which stands for Aspirin-Triggered Lipoxins. (wikipedia.org)
  • effects
  • In comparison with aspirin and eugenol, AEE produced more positive therapeutic effects than its precursors under the same molar quantity. (springer.com)
  • These side effects and structural instability are related to chemically carboxyl group of aspirin and hydroxyl group of eugenol. (springer.com)
  • blood
  • The attachment of platelets to certain leukocytes in the blood of patients with aspirin-sensitive asthma has also been shown to contribute to the overproduction of leukotrienes. (wikipedia.org)