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  • membrane
  • CD 16 (also known as FcgRIII), a low affinity receptor for the Fc portion of some IgGs known to be involved in antibody-dependent cellular cytotoxicity (ADCC), is the best-characterized membrane receptor responsible for triggering of target cell lysis by NK cells (Mandelboim et al, 1999, PNAS 96:5640-5644). (allindianpatents.com)
  • 1993
  • FcgRIIIB is present on polymorphonuclear granulocytes (PMN) as a glycosyl-phosphatidylinositol (GPI)-anchored receptor (FcyRIIIB isoform), which cannot trigger tumour cell killing (van de Winkel and Capel, 1993, supra). (allindianpatents.com)
  • amino
  • The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. (mybiosource.com)
  • Human Netrin-4 is synthesized as a 628 amino acid (aa) precursor that contains a 19 aa signal sequence, a 443 aa laminin-related region containing an N-terminal laminin globular domain (domain VI) followed by 3 laminin EGF-like repeats, and a 166 aa C-terminal domain rich in basic aa residues that serves as a heparin binding site. (rndsystems.com)
  • antibodies
  • In addition, FcyRIIIB exists as a soluble receptor in serum, and upon binding to antibodies may trigger side-effects via the formation of immune complexes in vivo. (allindianpatents.com)
  • subunit
  • Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine models of Alzheimer's disease (AD). (uni-muenchen.de)